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Comparison of percutaneous endoscopic lumbar discectomy and open lumbar discectomy in the treatment of adolescent lumbar disc herniation: A retrospective analysis.

World Neurosurg 2021 May 11. Epub 2021 May 11.

Department of Orthopedics, Peking University Third Hospital, Beijing, China. Electronic address:

Objective: To compare and analyze the efficacy and safety of percutaneous endoscopic lumbar discectomy (PELD) and open lumbar discectomy (OLD) for adolescent lumbar disc herniation (ALDH).

Methods: The clinical data of 257 patients with single-segment ALDH who underwent surgical treatment at our hospital from January 2015 to December 2019 were retrospectively collected. According to different surgical methods, these patients were divided into PELD group and OLD group. Read More

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Postoperative pain control after arthroscopic rotator cuff repair: Arthroscopy-guided continuous suprascapular nerve block versus ultrasound-guided continuous inter-scalene block.

Arthroscopy 2021 May 11. Epub 2021 May 11.

Department of Orthopaedic Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. Electronic address:

Purpose: We aimed to compare the clinical efficacy and safety of arthroscopy-guided continuous suprascapular nerve block (AS-SSNB) and ultrasound-guided continuous interscalene block (US-ISB) in postoperative analgesia in patients undergoing arthroscopic rotator cuff repair (ARCR).

Methods: A prospective study was performed between March and November 2020. In total, 76 patients were enrolled and divided into two groups: in 38 patients of group 1 (AS-SSNB), an indwelling catheter was introduced via the Neviaser portal under arthroscopic view before closing the portal at the end of the surgery; and in 38 patients of group 2 (US-ISB), an indwelling catheter was inserted directing towards the interscalene brachial plexus prior to the surgery under ultrasound-guidance. Read More

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Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery: Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Neurochirurgie 2021 May 11. Epub 2021 May 11.

Department of Biostatistics, Inonu University Medical Faculty, Malatya, Turkey.

Objectives: Effective postoperative pain management after lumbar disc surgery reduces complications and improves postoperative care. The purpose of this prospective, randomized, double-blind, placebo-controlled clinical study is to evaluate the effects of IV paracetamol and ibuprofen on postoperative pain, morphine consumption and side effects of morphine in patients who underwent lumbar disc surgery.

Materials And Methods: Seventy-five patients aged 18-85 years scheduled for lumbar disk surgery with a single level laminectomy included in this study. Read More

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Feasibility of Ultrasound-Guided Peritoneal Perfusion with Ozone in the Treatment of Chronic Pelvic Pain: A Bicenter Retrospective Analysis.

Pain Physician 2021 May;24(3):E367-E375

School of Anesthesiology, Weifang Medical University, Weifang City, Shandong Province, China; Department of Anesthesiology, Pain and Sleep Medicine, Aviation General Hospital of China Medical University and Beijing Institute of Translational Medicine, Chinese Academy of Sciences, Beijing, China.

Background: Numerous therapies have been developed for the treatment of chronic pelvic pain (CPP). Oxygen-ozone therapy is a new method for the treatment of CPP.

Objectives: This article evaluated the feasibility of ultrasound-guided peritoneal perfusion with ozone in patients with CPP. Read More

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Percutaneous Vertebroplasty Versus Kyphoplasty for Thoracolumbar Osteoporotic Vertebral Compression Fractures in Patients with Distant Lumbosacral Pain.

Pain Physician 2021 May;24(3):E349-E356

Department of Spinal Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.

Background: In clinical practice, we have found that the pain caused by thoracolumbar osteoporotic vertebral compression fracture (OVCF) is sometimes not limited to the level of the fractured vertebrae but instead occurs in areas far away from the injured vertebrae, such as the lower back, area surrounding the iliac crest, or buttocks, and this type of pain is known as distant lumbosacral pain. The pathogenesis of pain in distant regions caused by thoracolumbar OVCF remains unclear.

Objectives: To compare the clinical efficacy and imaging outcomes of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) in the treatment of distant lumbosacral pain accompanied by thoracolumbar OVCF and to explore the possible pathogenesis of distant lumbosacral pain caused by thoracolumbar OVCF. Read More

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Can Additional Facet Joint Block Improve the Clinical Outcome of Kyphoplasty for Acute Osteoporotic Vertebral Compression Fractures?

Pain Physician 2021 May;24(3):283-291

Department of Orthopedics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China; Geriatric Clinical Research Center of Chongqing, Chongqing, China.

Background: Percutaneous kyphoplasty (PKP) has been reported to provide a favorable analgesic effect for pain caused by osteoporotic vertebral compression fractures (OVCFs). However, a systematic review demonstrated that pain relief was only reported for approximately 86% of kyphoplasty treatments.

Objectives: To explore whether an additional facet joint block (FJB) can minimize pain and improve the clinical outcome of PKP in patients with acute OVCFs. Read More

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Full-Endoscopic Decompression with the Application of an Endoscopic-Matched Ultrasonic Osteotome for Removal of Ossification of the Thoracic Ligamentum Flavum.

Pain Physician 2021 May;24(3):275-281

Department of Orthopaedics, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

Background: Resection of the ossification of the thoracic ligamentum flavum (OTLF) with a high-speed burr may cause a high rate of perioperative complications, such as dural laceration and/or iatrogenic spinal cord injury.

Objectives: The aim of this study was to investigate the safety and feasibility of the endoscopic-matched ultrasonic osteotome in full-endoscopic spinal surgery for direct removal of OTLF.

Study Design: Retrospective study. Read More

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The Effect of Pethidine Analgesia on Labor Duration and Maternal-Fetal Outcomes.

Acta Biomed 2021 May 12;92(2):e2021065. Epub 2021 May 12.

Health Sciences University, Istanbul Kanuni Sultan Suleyman Research and Training Hospital, Department of Obstetrics and Gynecology, Istanbul/TURKEY.

Background: Opioid analgesics had been used from time to time for treating labor pain. However, their use have been concerning. The aim of this study is to evaluate the effect of pethidine on duration of active phase of labor, labor pain and maternal-neonatal outcomes. Read More

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Comparison of the modified sinus tarsi approach versus the extensile lateral approach for displaced intra-articular calcaneal fractures.

Ann Transl Med 2021 Apr;9(8):695

Department of Hand and Foot Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, China.

Background: This study sought to assess and compare the clinical efficacy and complications of a modified sinus tarsi approach (MSTA) and the extensile lateral approach (ELA) in the treatment of displaced intra-articular calcaneal fractures.

Methods: This retrospective study enrolled 108 patients (117 feet) with Sanders II-IV calcaneal fractures, including 52 patients (56 feet) in the MSTA group and 56 patients (61 feet) in the ELA group. The functional and radiological results of the affected feet were analysed retrospectively. Read More

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Single-Stage Combined Anterior Corpectomy and Posterior Instrumented Fusion in Tuberculous Spondylitis With Varying Degrees of Neurological Deficit.

Int J Spine Surg 2021 May 13. Epub 2021 May 13.

Metro Hospital, New Delhi, India.

Background: A combined anterior decompression and stabilization followed by posterior instrumented fusion promotes fusion of the affected segment of spine and prevents further progression of deformity. The objective of this study is to report on outcome of patients with tuberculous spondylitis, progressive neurologic deficit, and kyphotic deformity who underwent single-stage anterior corpectomy and fusion and posterior decompression with instrumented fusion.

Methods: A total of 49 patients (29 males, 20 females) with varying grades of neurological deficit due to tuberculosis of the spine (thoracic, thoracolumbar, and lumbar) were included in this prospective study. Read More

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The impact of common chronic conditions on health-related quality of life: a general population survey in Iran using EQ-5D-5L.

Cost Eff Resour Alloc 2021 May 13;19(1):28. Epub 2021 May 13.

Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Poursina Ave, 1417613191, Tehran, Iran.

Background: Diseases have undeniable effects on Health-Related Quality of Life (HRQoL). Chronic diseases, in particular, limit the productive potentials and HRQoL of individuals. EQ-5D is a very popular generic instrument, which can be used to estimate HRQoL scores in any diseases. Read More

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Role of paracervical block in reducing postoperative pain after laparoscopic hysterectomy: A systematic reivew and meta-analysis of randomized controlled trials.

J Gynecol Obstet Hum Reprod 2021 May 10:102156. Epub 2021 May 10.

Department of Obstetrics and Gynecology, Faculty of Medicine, Al Azhar University for Girls, Cairo, Egypt.

Objective: We aimed to perform a systematic review and meta-analysis in order to evaluate the effect of paracervical anesthetic block among women undergoing laparoscopic hysterectomy.

Methods: A systematic search was done in Cochrane Library, PubMed, ISI web of science, and Scopus during January 2021. We selected randomized clinical trials (RCTs) compared paracervical anesthetic block versus normal saline (control group) among women undergoing laparoscopic hysterectomy. Read More

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The effect of different micro-osteoperforation depths on the rate of orthodontic tooth movement: A single-center, single-blind, randomized clinical trial.

Korean J Orthod 2021 May;51(3):157-165

Department of Orthodontics, Faculty of Dentistry, Ondokuz Mayıs University, Atakum, Samsun, Turkey.

Objective: This study aimed to identify the clinical effectiveness of two different penetration depths of micro-osteoperforations (MOPs) on the rate of orthodontic tooth movement.

Methods: Twenty-four patients requiring the removal of the upper first premolar teeth were selected and randomly divided into two groups. The control group participants did not undergo MOPs. Read More

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A comparison of adductor canal block before and after thigh tourniquet during knee arthroscopy: A randomized, blinded study.

Korean J Anesthesiol 2021 May 13. Epub 2021 May 13.

Department of Anesthesiology, Istanbul Medipol University, School of Medicine, Istanbul, Turkey.

Background: Adductor canal block (ACB) provides effective analgesia management after arthroscopic knee surgery. However, there is insufficient data about performing ACB before or after inflation of a thigh tourniquet. We aimed to investigate the efficacy of ACB when it is performed before and after thigh tourniquet and evaluate motor weakness. Read More

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Wound infiltration of dexmedetomidine as an adjunct to local anesthesia in postoperative analgesia for lumbar surgery: a systematic review and meta-analysis.

Minerva Anestesiol 2021 May 13. Epub 2021 May 13.

Department of Orthopedics, Northern Jiangsu People's Hospital, Clinical Medical College of Yangzhou University, Yangzhou, China -

Introduction: The vast majority of patients undergoing lumbar surgery experience varying degrees of incision pain, leading to prolonged postoperative recovery and poor satisfaction with treatment. The objective of this meta-analysis was to evaluate the efficacy and safety of dexmedetomidine as an adjunct to local anesthesia for postoperative pain control after lumbar surgery.

Evidence Acquisition: Two authors independently searched eligible random controlled trials in electronic databases, including PubMed, Embase, Cochrane Library, Web of Science, CNKI (China National Knowledge Infrastructure), CBM (The Chinese BioMedical database) using the search terms 'dexmedetomidine', 'infiltration', and 'lumbar'. Read More

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Non-pharmacological therapies for pain management in Parkinson's disease: A systematic review.

Acta Neurol Scand 2021 May 13. Epub 2021 May 13.

Neurology, Parkinson's Clinic of Eastern Toronto & Movement Disorders Centre, Toronto, ON, Canada.

Among the various non-motor symptoms of Parkinson's disease (PD), pain is often cited as the most common and debilitating feature. Currently, the literature contains gaps in knowledge with respect to the various forms of treatment available, particularly non-pharmacological therapies. Thus, the purpose of this systematic review is to provide an examination of the literature on non-pharmacological therapies for pain in PD. Read More

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Evaluation of nasal symptoms to distinguish eosinophilic from noneosinophilic nasal polyps based on peripheral blood.

Allergy Asthma Proc 2021 May;42(3):214-221

From the Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China.

Patients with eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) have poorer outcomes after endoscopic sinus surgery and a higher recurrence rate. This study aimed to investigate the profile of clinical symptoms of eCRSwNP and the related risk factors. We prospectively enrolled 298 inpatients with CRSwNP from February 2019 to December 2019. Read More

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Patient-specific instrumentation combined with a new tool for gap balancing is useful in total knee replacement: a 3-year follow-up of a retrospective study.

J Orthop Surg Res 2021 May 12;16(1):309. Epub 2021 May 12.

Department of Orthopaedics, The Third Hospital of Changsha, Changsha, China.

Objective: The purpose of this study was to determine whether the gap-balancing technique with patient-specific instrumentation (PSI) and a new balancing device in total knee arthroplasty (TKA) can improve knee function to a greater extent than can the measured resection technique.

Materials And Methods: Data from 150 patients who underwent TKA from August 2014 to June 2016 were studied retrospectively. The gap-balancing technique assisted by PSI and the new balancing device was used in 80 patients (82 knees), and the measured resection technique was used in 70 patients (70 knees). Read More

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Impact of sleep duration, physical activity, and screen time on health-related quality of life in children and adolescents.

Health Qual Life Outcomes 2021 May 12;19(1):145. Epub 2021 May 12.

Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Room 115, 1/F, New Clinical Building, 102 Pokfulam Road, Queen Mary Hospital, Hong Kong, SAR, China.

Background: Existing studies on health-related quality of life (HRQoL) mainly covered single growth stages of childhood or adolescence and did not report on the trends in the relationships of HRQoL with sleep duration, physical activity, and screen time. This study aimed to establish the population norm of HRQoL in children and adolescents aged 6-17 years and examine the associations of screen time, sleep duration, and physical activity with HRQoL in this population.

Methods: We conducted a large-scale cross-sectional population-based survey study of Hong Kong children and adolescents aged 6 to 17 years. Read More

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Volar locking plate versus external fixation for unstable distal radius fractures: a systematic review and meta-analysis based on randomized controlled trials.

BMC Musculoskelet Disord 2021 May 12;22(1):433. Epub 2021 May 12.

Department of Orthopedics, The First People's Hospital of Longquanyi District, 610100, Chengdu, China.

Background: The outcomes for volar locking plate (VLP) and external fixation (EF) in distal radius fracture cases remain controversial. The current study of randomized controlled trials (RCTs) aimed to assess VLP and EF, which might benefit distal radius fracture cases.

Methods: RCTs comparing VLP and EF in distal radius fracture cases, until 18 March 2020, were systematically reviewed and summarized. Read More

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Radiological changes in sagittal parameters after C1-C2 arthrodesis and their clinical correlation: Is there a difference between traumatic and non-traumatic causes?

Int J Neurosci 2021 May 12:1-10. Epub 2021 May 12.

Department of Spine Service, Indian Spinal Injuries Centre, Vasant Kunj, New Delhi, India.

: Compensatory changes in cervical sagittal alignment after C1-C2 arthrodesis have been reported in a few studies. No studies have explored the differences in these compensatory changes between traumatic and non-traumatic pathologies. Conflicting reports exist on the correlation between cervical sagittal parameters and neck pain or function. Read More

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Reliability of the Patient and Observer Scar Assessment Scale in Evaluating Linear Scars after Thyroidectomy.

Adv Skin Wound Care 2021 Jun;34(6):1-6

In the Department of Plastic and Reconstructive Surgery, Korea University Hospital, Seoul, Republic of Korea, Jae-Ho Chung, MD, PhD, is Clinical Assistant Professor; Sang-Ho Kwon, MD, is a resident; Ki-Jae Kim, MD, MS, is a resident; Jae-Min Lee, MD, MS, is a resident; Jeong-Min Yoon, MD, MS, is Public Health Physician; Jeong-Hyun Cheon, MD, MS, is Clinical Instructor; Eul-Sik Yoon, MD, PhD, is Professor; Seung-Ha Park, MD, PhD, MBA, is Professor. The authors have disclosed no financial relationships related to this article. Submitted October 19, 2020; accepted in revised form December 4, 2020.

Objective: To compare the reliability of the Patient and Observer Scar Assessment Scale (POSAS) with the Vancouver Scar Scale (VSS) in evaluating thyroidectomy scars.

Methods: At 6 months after the operation, 112 patients who underwent thyroid surgery via collar neck incision were evaluated by two blinded plastic surgeons and two senior residents using the VSS and the observer component of the POSAS. In addition, the observer-reported VAS score and patient-reported Likert score were evaluated. Read More

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Short-term functional outcome after fast-track primary total knee arthroplasty: analysis of 623 patients.

Acta Orthop 2021 May 12:1-6. Epub 2021 May 12.

Department of Orthopaedics, Reinier Haga Orthopedisch Centrum, Zoetermeer, the Netherlands.

Background and purpose - Early functional outcome after total knee arthroplasty (TKA) has been described before, but without focus on the presence of certain functional recovery patterns. We investigated patterns of functional recovery during the first 3 months after TKA and determined characteristics for non-responders in functional outcome.Patients and methods - All primary TKA in a fast-track setting with complete patient-reported outcome measures (PROMs) preoperatively, at 6 weeks, and 3 months postoperatively were included. Read More

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Preoperative Fluoroscopically Guided Regional Erector Spinae Plane Blocks Reduce Opioid Use, Increase Mobilization, and Reduce Length of Stay Following Lumbar Spine Fusion.

Global Spine J 2021 May 12:21925682211010740. Epub 2021 May 12.

University of Utah, Salt Lake City, UT, USA.

Study Design: Retrospective review.

Objective: To determine the effectiveness of erector spinae plane (ESP) blocks at improving perioperative pain control and function following lumbar spine fusions.

Methods: A retrospective analysis was performed on patients undergoing 3 level posterolateral lumbar fusions. Read More

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An evaluation of the correlation between the severity and frequency of migraine and the Buss-Perry Aggression Scale.

Acta Neurol Belg 2021 May 11. Epub 2021 May 11.

Department of Neurology, University of Health Sciences, Prof.Dr.Cemil Taşçıoğlu City Hospital, Istanbul, Turkey.

It is important to identify concomitant psychological factors such as depression and aggression in patients with migraine. In this study, our objective was to demonstrate the difference of aggression scores in patients with migraine compared with normal scores, and whether the severity of the disease and the frequency of pain had an impact. Ninety-nine patients with migraine and 67 healthy controls who presented to the Okmeydanı Training and Research Hospital were included in the study. Read More

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Excellent response to asfotase alfa treatment in an adolescent patient with hypophosphatasia.

JIMD Rep 2021 May 3;59(1):10-15. Epub 2021 Feb 3.

Department of Clinical Genetics Copenhagen University Hospital Copenhagen Denmark.

Hypophosphatasia (HPP) is a rare inherited metabolic disorder characterized by deficient activity of alkaline phosphatase, causing defective mineralization of bones and teeth. The symptoms vary from no symptoms to stillbirth or skeletal manifestations. Since 2015, asfotase alfa, an enzyme replacement treatment, has been approved for pediatric use in some jurisdictions. Read More

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The impact of post-urethroplasty erectile dysfunction on the quality of life and treatment satisfaction.

Cent European J Urol 2021 15;74(1):116-120. Epub 2021 Jan 15.

Medical University of Gdańsk, Department of Urology, Gdańsk, Poland.

Introduction: The aim of this article was to assess the influence of sexual disorders after urethroplasty on patient's quality of life (QoL) and satisfaction of treatment.

Material And Methods: We studied 106 sexually active patients who underwent urethroplasty due to urethral stricture. Patients completed the Urethral Stricture Surgery - Patient Reported Outcome Measure (USS - PROM) and International Index of Erectile Function (IIEF-5) questionnaires before and after the treatment. Read More

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January 2021

Comparative evaluation of retrograde intrarenal surgery, antegrade ureterorenoscopy and laparoscopic ureterolithotomy in the treatment of impacted proximal ureteral stones larger than 1.5 cm.

Cent European J Urol 2021 23;74(1):57-63. Epub 2021 Jan 23.

Department of Urology, Haseki Traning and Research Hospital, Haseki, Turkey.

Introduction: The aim of this article was to compare retrograde intrarenal surgery (RIRS), antegrade ureterorenoscopy (URS), and laparoscopic ureterolithotomy (LU) for impacted proximal ureter stones larger than 1.5 cm in terms of operative data, success, complications, auxiliary treatment rates, and visual analog scale (VAS) scores.

Material And Methods: Medical records of patients undergoing RIRS, antegrade URS, or LU were retrospectively reviewed. Read More

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January 2021

Responsiveness of the self-measured 6-minute walking test and the Timed Up and Go test in patients with degenerative lumbar disorders.

J Neurosurg Spine 2021 May 7. Epub 2021 May 7.

Department of Neurosurgery, University Hospital Zurich and Clinical Neuroscience Center, University of Zurich.

Objective: The 6-minute walking test (6WT) and the Timed Up and Go (TUG) test are two of the most commonly applied standardized measures of objective functional impairment that help support clinical decision-making for patients undergoing surgery for degenerative lumbar disorders. This study correlates smartphone-app-based 6WT and TUG results to evaluate their responsiveness.

Methods: In a prospective study, 49 consecutive patients were assessed preoperatively and 6 weeks postoperatively using the 6WT, the TUG test, and commonly used patient-reported outcome measures. Read More

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The predictive ability of EQ-5D-3L compared to the LACE index and its association with 30-day post-hospitalization outcomes.

Qual Life Res 2021 May 11. Epub 2021 May 11.

2-040 Li Ka Shing Centre for Health Research Innovation, Alberta PROMs and EQ-5D Research and Support Unit (APERSU), School of Public Health, University of Alberta, EdmontonAlberta, AB, T6G 2E1, Canada.

Purpose: To examine whether the EQ-5D-3L at the time of discharge from hospital provides additional prognostic information above the LACE index for 30-day post-discharge hospital readmission and to explore the association of EQ-5D-3L with readmissions, emergency department (ED) visits, and death within the same period.

Methods: Using data (n = 495; mean age 62.9 years (SD 18. Read More

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