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Prevalence and Factors Affecting Postoperative Delirium in a Neurosurgical Intensive Care Unit.

J Neurosci Nurs 2021 Jun 10. Epub 2021 Jun 10.

Questions or comments about this article may be directed to Gulsah Kose, Lecturer, PhD RN, at G.K. is Assistant Professor, Health Science Faculty, Department of Nursing, Mugla Sitki Kocman University, Muğla, Turkey. Keziban Şirin, RN, is Chief Nurse, Cerrahpasa Medical Faculty, Department of Neurosurgery, Istanbul University-Cerrahpasa, Istanbul, Turkey. Mehtap Balin Inel, is NSICU Nurse and Neurosurgical Nurse, Cerrahpasa Medical Faculty, Department of Neurosurgery, Istanbul University-Cerrahpasa, Istanbul, Turkey. Sevcan Mertoglu, is NSICU Nurse and Neurosurgical Nurse, Cerrahpasa Medical Faculty, Department of Neurosurgery, Istanbul University-Cerrahpasa, Istanbul, Turkey. Raziye Aksakal, is NSICU Nurse and Neurosurgical Nurse, Cerrahpasa Medical Faculty, Department of Neurosurgery, Istanbul University-Cerrahpasa, Istanbul, Turkey. Şule Kurucu, is NSICU Nurse and Neurosurgical Nurse, Cerrahpasa Medical Faculty, Department of Neurosurgery, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Abstract: PURPOSE: The aim of this study was to identify the prevalence of, and factors affecting, postoperative delirium (POD) in patients in the neurosurgical intensive care unit. METHODS: A cross-sectional study of 127 Turkish neurosurgical intensive care unit patients admitted between May 2018 and May 2019 was conducted. Patients were assessed for the development of POD using the Intensive Care Delirium Screening Checklist. Read More

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Structural changes in endocrine pancreas of male Wistar rats due to chronic cola drink consumption. Role of PDX-1.

PLoS One 2021 11;16(6):e0243340. Epub 2021 Jun 11.

Facultad de Medicina, CONICET, Universidad de Buenos Aires, Instituto Alberto C. Taquini de Investigaciones en Medicina Traslacional (IATIMET), Buenos Aires, Argentina.

Aim: The objective of this work was to analyze the structural changes of the pancreatic islets in rats, after 6 month consuming regular and light cola for 6 months. Also, we have analyzed the possible role of PDX-1 in that process. Finally, with the available knowledge, we propose a general working hypothesis that explains the succession of phenomena observed. Read More

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Implants Placed in Adolescents Followed for Up to 15.5 Years: A Retrospective Case Series.

Int J Oral Maxillofac Implants 2021 May-Jun;36(3):561-568

Purpose: To evaluate the clinical outcomes of unsplinted implant-supported single crowns placed in adolescents, ages 10 to 19 years, and followed up from 5 to 15 years.

Materials And Methods: This retrospective case series evaluated the outcomes of implant-supported single crowns placed in adolescents between June 2002 and January 2015. The patients were treated with locking-taper connection implants under a two-stage rehabilitation technique. Read More

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Quality of Life and Functioning of People With Mental Disorders Who Underwent Deinstitutionalization Using Assisted Living Facilities: A Cross-Sectional Study.

Front Psychol 2021 25;12:622973. Epub 2021 May 25.

Graduate Program in Pharmaceutical Sciences, University of Sorocaba, Sorocaba, Brazil.

Context: People with mental disorders can acquire long-term disabilities, which could impair their functioning and quality of life (QoL), requiring permanent care and social support. Systematic data on QoL and functioning, which could support a better management of these people, were not available.

Objective: To analyze the QoL, level of functioning and their association with sociodemographic and clinical factors of people with mental disorders who underwent deinstitutionalization using assisted living facilities. Read More

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The impact of human papilloma virus status on the prediction of head and neck cancer chemoradiotherapy outcomes using the pre-treatment apparent diffusion coefficient.

Br J Radiol 2021 Jun 11:20210333. Epub 2021 Jun 11.

School of Biomedical Engineering and Imaging Sciences, St Thomas' Hospital, King's College, London, SE1 7EH, United Kingdom.

Objective: To determine the impact of Human Papilloma Virus (HPV) oropharyngeal cancer (OPC) status on the prediction of head and neck squamous cell cancer (HNSCC) chemoradiotherapy (CRT) outcomes with pre-treatment quantitative diffusion-weighted magnetic resonance imaging (DW-MRI).

Methods: Following ethical approval, 65 participants (53 male, age 59.9 ± 7. Read More

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Circumcision versus Preputioplasty for BXO - a randomised controlled feasibility trial.

BJU Int 2021 Jun 10. Epub 2021 Jun 10.

Alder Hey Children's Hospital, Liverpool, United Kingdom.

Objectives: To determine: (i) feasibility for an RCT comparing circumcision to preputioplasty and intralesional triamcinolone (PIT) to treat Balanitis Xerotica Obliterans (BXO) and (ii) patient outcomes to inform future study design.

Patients And Methods: Approval was obtained from HRA/REC (16/NW/0364) and trial protocol registered (NCT02854995). Twenty boys (2-16 years) with BXO were randomized to either circumcision or PIT (online parallel group 1:1 allocation, non blinded). Read More

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Inflammatory biomarkers in the pathogenesis of respiratory dysfunction in people living with HIV.

Curr HIV Res 2021 Jun 6. Epub 2021 Jun 6.

Infectious Diseases Unit, General University Hospital of Alicante, Alicante, Spain.

Background: Although the association between HIV infection and airway obstruction is well known, its etiopathogenesis is not clear.

Objectives: Our aim was to analyze the association between biomarkers of systemic inflammation and bacterial translocation and pulmonary function tests in HIV-infected patients and compare the results between smokers and non-smokers.

Method: It was a cross-sectional, observational study. Read More

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Nationwide multicentre comparison of preoperative biometry and predictability of cataract surgery in Japan.

Br J Ophthalmol 2021 Jun 9. Epub 2021 Jun 9.

Ophthalmology, Kanazawa Medical University, Kahoku-gun, Japan.

Aim: To compare the preoperative biometric data and the refractive accuracy of cataract surgery among major surgical sites in a nationwide multicentre study.

Methods: We prospectively obtained the preoperative biometric data of 2143 eyes of 2143 consecutive patients undergoing standard cataract surgery at major 12 facilities and compared the preoperative biometry as well as the postoperative refractive accuracy among them.

Results: We found significant differences in most preoperative variables, such as axial length (one-way analysis of variance, p=0. Read More

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Binge eating symptoms are associated with the severity of premenstrual symptoms among university students, cross sectional study from Palestine.

J Eat Disord 2021 Jun 9;9(1):68. Epub 2021 Jun 9.

Program of Therapeutic Nutrition, College of Medicine and Health Sciences, Palestine Polytechnic University, Hebron, Palestine.

Background: Premenstrual syndrome (PMS) is considered one of the most prevailing disorders among childbearing age women that could considerably interfere with daily living activities life. PMS is underrecognized in Palestine. It is reported that binge eating symptoms are significantly related to premenstrual syndrome. Read More

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Impairment of left atrial function in pediatric patients with repaired tetralogy of Fallot: a cardiovascular magnetic resonance imaging study.

Int J Cardiovasc Imaging 2021 Jun 8. Epub 2021 Jun 8.

Diagnostic Imaging Center, Shanghai Children's Medical Center Affiliated With Shanghai Jiao Tong University School of Medicine, 1678 Dong Fang Road, Shanghai, 200127, People's Republic of China.

We aimed to assess left atrial (LA) strain before LA dilatation in patients with repaired tetralogy of Fallot (rTOF) compared with healthy controls. We also determined the effects of right atrial (RA) dilatation on LA performance using cardiovascular magnetic resonance-feature tracking (CMR-FT). Forty-nine pediatric patients with rTOF and 36 age- and sex-matched healthy controls were prospectively recruited between June 2017 and August 2019. Read More

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Determining Anterior Fontanel Size and Associated Factors Among Term Neonates on the First Day of Life Born at Jimma University Medical Center (JUMC), Southwest Ethiopia: A Linear Regression Model.

Pediatric Health Med Ther 2021 1;12:269-278. Epub 2021 Jun 1.

School of Medicine, College of Health and Medical Science, Haramaya University, Harar, Ethiopia.

Background: Knowledge of the normal variation in AF size may be helpful to cue early diagnosis of congenital hypothyroidism, hyperthyroidism, cardiac disease, meningitis, degree of dehydration or provide a clue to disorders of neural and skeletal development. However, the data is scarce. Therefore, this study was aimed to determine AF size and associated factors among term neonates on the first day of life born in Jimma University Medical Center (JUMC), Southwest Ethiopia. Read More

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A prospective randomized clinical study of perioperative oral thyroid hormone treatment for children undergoing surgery for congenital heart diseases.

Ann Pediatr Cardiol 2021 Apr-Jun;14(2):170-177. Epub 2021 Feb 16.

Department of Pediatric Cardiothoracic Surgery, Fortis Escorts Heart Institute, New Delhi, India.

Context: Thyroid hormone deficiency is known to occur after cardiac surgery and known as nonthyroid illness (NTI). The beneficial role of perioperative thyroid hormone supplementation in children has been debatable more so with oral supplementation.

Aims: The aim is to evaluate the role of pre-operative oral thyroid hormone therapy in preventing NTI. Read More

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February 2021

[Predictive value of lactate concentration combined with lactate clearance rate in the prognosis of neonatal septic shock].

Zhonghua Er Ke Za Zhi 2021 Jun;59(6):489-494

Department of Neonatal Intensive Care, Xi'an Children's Hospital, Xi'an Jiao Tong University, Xi'an 710003, China.

To investigate the predictive value of lactate concentration within 1 h after admission combined with lactate clearance rate (LC) at 6 h after fluid resuscitation in prognosis of neonatal septic shock. In this retrospective study, 58 newborns with septic shock admitted to the Neonatal Intensive Care Unit of Xi'an Children's Hospital,Xi'an Jiao Tong University from June 2016 to March 2020 were enrolled. According to the mortality within 60 days after admission,which was also set as the end point, the patients were divided into death group and survival group. Read More

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Effects of the COVID-19 Lockdown on Neuromuscular Performance and Body Composition in Elite Futsal Players.

J Strength Cond Res 2021 Jun 3. Epub 2021 Jun 3.

UCAM Research Center for High Performance Sport, Catholic University of Murcia, Murcia, Spain; Faculty of Sport Sciences, Catholic University of Murcia, Murcia, Spain; Strength and Conditioning Society, Rome, Italy; Research Group Murcia Soccer Federation, Murcia, Spain; Sports Science Center (CCD), Colombian Ministry of Sport (Mindeporte), Bogotá, Colombia; Masira Research Institute, University of Santander (UDES), Bucaramanga, Colombia; Laboratory of Analysis of Sport Performance, University of Basque Country, Vitoria, Spain; Faculty of Kinesiology, University of Zagreb, Zagreb, Croatia; NAR-Nucleus of High Performance in Sport, São Paulo, Brazil; Department of Human Movement Sciences, Federal University of São Paulo, São Paulo, Brazil; and Department of Sport and Exercise, University of South Wales, Pontypridd, Wales.

Abstract: Spyrou, K, Alcaraz, PE, Marín-Cascales, E, Herrero-Carrasco, R, Cohen, DD, Calleja-Gonzalez, J, Pereira, LA, Loturco, I, and Freitas, TT. Effects of the COVID-19 lockdown on neuromuscular performance and body composition in elite futsal players. J Strength Cond Res XX(X): 000-000, 2021-Recent world events (i. Read More

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A comparative study of Terumo radial Band® and PreludeSYNC hemostasis compression device after transradial coronary catheterization.

Anatol J Cardiol 2021 Jun;25(6):402-406

Rawalpindi Institute of Cardiology; Rawalpindi-Pakistan.

Objective: Novel hemostasis strategies, including PreludeSYNC DISTAL, Merit Medical Systems, Inc. South Jordan, UT, USA (PSD) radial compression device for distal radial artery (DRA) access, have been described for radial access protocols. This study aimed to compare the safety profile of PSD and Terumo radial (TR) Band®. Read More

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Age related treatment effect in type II Spinal Muscular Atrophy pediatric patients treated with nusinersen.

Neuromuscul Disord 2021 Apr 2. Epub 2021 Apr 2.

Pediatric Neurology, Università Cattolica del Sacro Cuore, Rome, Italy; Centro Clinico Nemo, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy. Electronic address:

Previous natural history studies suggest that type II SMA patients remain stable over one year but show some progression over two years. Since nusinersen approval, there has been increasing attention to identify more specific age-related changes. The aim of the study was to establish 12-month changes in a cohort of pediatric type II SMA treated with nusinersen and to establish possible patterns of treatment effect in relation to different variables such as age, baseline value and SMN2 copy number. Read More

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[Transcranial sonographic characteristics of Parkinson's disease with symptoms of restless legs syndrome].

Zhonghua Yi Xue Za Zhi 2021 Jun;101(21):1566-1571

Department of Neurology, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China.

To evaluate the transcranial sonographic characteristics in patients with Parkinson's disease (PD) with symptoms of restless legs syndrome (RLS). Patients with diagnosis of definite PD from the Second Affiliated Hospital of Soochow University and 3 other participating hospitals between September 2018 and December 2019 were consecutively enrolled. Concurrent RLS symptoms were determined using Non-motor Symptoms Questionnaire. Read More

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Ten-year follow-up of social functioning and behaviour problems in people with schizophrenia and related disorders.

Int J Soc Psychiatry 2021 Jun 6:207640211023083. Epub 2021 Jun 6.

Mental Health Service, University Hospital Virgen del Rocío, Seville, Spain.

Background: In recent years, several variables in the course of schizophrenia and related psychotic disorders have been studied. However, an instrumental analysis of the evolution of social functioning and behaviour problems has scarcely been explored.

Aim: To analyse the evolution of social functioning and behaviour problems and find any diagnosis or gender differences. Read More

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Factors influencing the removal torque of palatal implant used for orthodontic anchorage.

Prog Orthod 2021 Jun 7;22(1):16. Epub 2021 Jun 7.

Clinic of Orthodontics and Pediatric Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, CH-8032, Zurich, Switzerland.

Background: A non-invasive method has recently been introduced to remove osseo-integrated palatal implants by using the implantation ratchet which is designed to screw in or unscrew the implants. Although a proof of concept has been published, the torque involved to successfully explant have not been investigated so far. The aim of this study was to assess the removal torque required to explant osseo-integrated and orthodontically utilized palatal implants, and to identify potentially influencing variables. Read More

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Moral Resilience in Nursing Education: Exploring Undergraduate Nursing Students Perceptions of Resilience in Relation to Ethical Ideology.

SAGE Open Nurs 2021 Jan-Dec;7:23779608211017798. Epub 2021 May 21.

Faculty of Nursing, University of Regina, Regina, Saskatchewan, Canada.

Introduction: Moral resilience has recently been proposed as one strategy to address moral distress in nurses and nursing students. Central to nursing students' capacity for moral resilience is how they understood and enact resilience with an element of realism, suggesting an ethical, ideological influence. Resilience is shown to differ significantly across students, and possibly because of a disconnect between a students' perceived resilience and their ethical ideology. Read More

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Asphyxia and Neonatal Respiratory Distress Syndrome Are Independent Predictors of the Non-response to Inhaled Nitric Oxide in the Newborns With PPHN.

Front Pediatr 2021 20;9:665830. Epub 2021 May 20.

Neonatology Department, Anhui Provincial Children Hospital, Hefei, China.

Not all the neonates respond with improvement in oxygenation following inhaled nitric oxide treatment (iNO) treatment. The aim of this study was to assess the independent risk factors associated with non-response to iNO during the 2 weeks of postnatal treatment in neonates diagnosed with persistent pulmonary hypertension (PPHN). This retrospective cohort study included all newborns with PPHN who received iNO treatment for more than 24 h. Read More

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Associations Between Single-Child Status and Metabolic Syndrome in Children and Adolescents in China.

Front Pediatr 2021 20;9:661164. Epub 2021 May 20.

Menzies Health Institute Queensland, Griffith University, Brisbane, QLD, Australia.

To evaluate the associations between single-child status and metabolic syndrome (MS) and to identify the highest risk group of MS among single children. Differences in participants' characteristics by sex were examined by Student's -test for continuous variables and Pearson's chi-squared test for categorical variables. Multivariate logistic regression analysis was performed to estimate the odds ratios () and 95% confidence intervals () for MS and its components according to the single-child status. Read More

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Comparison of Analgesic Efficacy of Dexamethasone versus Tramadol in Combination with Ropivacaine in Caudal Anesthesia for Children Undergoing Lower Abdominal Surgeries.

Anesth Essays Res 2020 Jul-Sep;14(3):515-520. Epub 2021 Mar 22.

Department of Anaesthesia and Intensive Care, GMC, Jammu, Jammu and Kashmir, India.

Background: Caudal anesthesia has emerged as a reliable and effective anesthetic technique in the pediatric age group. However, the limited duration of action of the local anesthetic drugs proves to one of the major hindrances in the complete utilization of caudal block as an effective analgesic technique. To overcome this shortcoming, adjuvant drugs were introduced into clinical practice. Read More

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Comparison of Videolaryngoscope and Intubating Laryngeal Mask Airway for Tracheal Intubation with Manual-in-line Stabilization in Patients Undergoing Cervical Spine Surgery.

Anesth Essays Res 2020 Jul-Sep;14(3):485-491. Epub 2020 Nov 26.

Department of Anaesthesiology and Critical Care, Vardhaman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

Background: This prospective, randomized study compared CMAC videolaryngoscope with intubating laryngeal mask airway (ILMA) for intubation under manual-in-line-stabilization (MILS) in patients undergoing cervical spine surgery. Settings and Design: Sixty-five ASA Physical Status Classes I and II patients aged 18-65 years undergoing elective cervical spine surgery were randomly allocated into two groups: group CM-intubation with CMAC videolaryngoscope ( = 33) and Group IL-intubation using ILMA ( = 32).

Materials And Methods: Intubation was performed in all patients after the application of MILS. Read More

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November 2020

Comparison of Analgesic Efficacy of Ultrasound-Guided Transversus Abdominus Plane Block and Caudal Block for Inguinal Hernia Repair in Pediatric Population: A Single-Blinded, Randomized Controlled Study.

Anesth Essays Res 2020 Jul-Sep;14(3):478-484. Epub 2021 Mar 22.

Department of Anesthesiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

Background: Caudal analgesia was a widely practiced regional anesthesia technique in pediatric population. Transversus abdominus plane block (TAP) block has recently emerged as a promising analgesic method in pediatric lower abdominal surgeries.

Aim: This study aimed to compare the analgesic efficacy of ultrasound-guided TAP block and caudal block. Read More

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Comparison of Propofol-Dexmedetomidine-Based Intravenous and Sevoflurane-Based Inhalational Anesthesia in Patients Undergoing Modified Radical Mastectomy.

Anesth Essays Res 2020 Jul-Sep;14(3):420-424. Epub 2021 Mar 22.

Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India.

Background And Aim: Total intravenous anesthesia (TIVA) has proven advantage over inhalational anesthesia in terms of stable hemodynamic, eco-friendly, and good recovery profile, but apprehension regarding adequate depth of anesthesia and intraoperative recall is still pertaining. This study aims to compare propofol-dexmedetomidine-based TIVA with sevoflurane-based inhalational anesthesia in modified radical mastectomy in terms of depth of anesthesia, intraoperative recall, recovery profile, and hemodynamic status.

Settings And Design: This prospective randomized controlled study was conducted at a tertiary care center over a time frame of 1 year. Read More

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Comparison of Oral Clonidine and Gabapentin Premedication for Attenuation of Pressor Response to Laryngoscopy and Endotracheal Intubation.

Anesth Essays Res 2020 Jul-Sep;14(3):412-419. Epub 2021 Mar 22.

Batra Hospital and Medical Research Centre, New Delhi, India.

Background: During the administration of general anesthesia, direct laryngoscopy and endotracheal intubation cause an increase in heart rate, arterial pressure, and dysrhythmias in upto 90% of patients. These changes can be particularly hazardous for patients with cerebral or coronary diseases. Both clonidine and gabapentin have been used for anesthetic effects, but a better drug for controlling hemodynamic parameters is being investigated. Read More

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Real-World Claims Analyses of Comorbidity Burden, Treatment Pattern, Healthcare Resource Utilization, and Costs in Pediatric Psoriasis.

Adv Ther 2021 Jun 6. Epub 2021 Jun 6.

St. Luke's Children's Hospital, Boise, ID, USA.

Introduction: There are limited real-world data on treatment patterns, comorbidities, and healthcare burden in pediatric patients with psoriasis. We examined patient demographics, comorbidity burden, treatment patterns, and healthcare use and costs in pediatric psoriasis.

Methods: A retrospective, real-world, exploratory study was conducted using US claims databases. Read More

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Parent's sociodemographic factors, physical activity and active commuting are predictors of independent mobility to school.

Int J Health Geogr 2021 Jun 6;20(1):26. Epub 2021 Jun 6.

Department of Physical Education and Sports, PROFITH "PROmoting FITness and Health Through Physical Activity" Research Group, Sport and Health University Research Institute (iMUDS), Faculty of Sport Sciences, University of Granada, Granada, Spain.

Background: Independent mobility (IM) provides young people with many opportunities to increase their autonomy and physical activity (PA). This study aimed to analyse whether the parent's PA, active commuting to work and sociodemographic factors serve as predictors of IM to school in children and adolescents.

Methods: A total of 684 parents (52. Read More

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Accuracy of bracket position using thermoplastic and 3D-printed indirect bonding trays.

Int J Comput Dent 2021 Jun;24(2):133-145

Aim: The positional accuracy of bracket placement planned through tooth setup vs actual placement was evaluated by means of conventional thermoplastic indirect bonding trays and customized 3D-printed indirect bonding trays.

Materials And Methods: A total of 280 bracket positions placed on the crowns of 10 dental plaster models were evaluated. The manual setup method and a thermoplastic indirect bonding tray were used for the manual group. Read More

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