Radiol Cardiothorac Imaging 2021 Apr 15;3(2):e190219. Epub 2021 Apr 15.
Department of Biomedical Engineering and Physics (B.D.d.V., I.I.), Cardiovascular Institute (B.D.d.V., I.I.), and Department of Radiology and Nuclear Medicine (I.I.), Amsterdam University Medical Center, Meibergdreef 9, Amsterdam, the Netherlands; and Image Sciences Institute (B.D.d.V., N.L., I.I.) and Department of Radiology (P.A.d.J., I.I.), University Medical Center Utrecht, Utrecht, the Netherlands.
Purpose: To examine the prognostic value of location-specific arterial calcification quantities at lung screening low-dose CT for the prediction of cardiovascular disease (CVD) mortality.
Materials And Methods: This retrospective study included 5564 participants who underwent low-dose CT from the National Lung Screening Trial between August 2002 and April 2004, who were followed until December 2009. A deep learning network was trained to quantify six types of vascular calcification: thoracic aorta calcification (TAC); aortic and mitral valve calcification; and coronary artery calcification (CAC) of the left main, the left anterior descending, and the right coronary artery. Read More