271,309 results match your criteria values group

Percentile values for serum levels of vitamins A and D in Iranian children and adolescents: The CASPIAN-V study.

Nutrition 2021 Apr 30;90:111307. Epub 2021 Apr 30.

Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.

Objectives: The reference values to determine vitamin A and D deficiency may vary based on ethnicity, age, and region of residence. The aim of this study was to determine the reference interval of circulating vitamin A and D levels among Iranian children and adolescents based on sex, age, and region of residence.

Methods: This nationwide cross-sectional study was performed with 2596 students 7 to 18 y of age from the CASPIAN-V (Childhood and Adolescence Surveillance and Prevention of Adult Non- communicable disease) study. Read More

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Copeptin combined with National Early Warning Score for predicting survival in elderly critical ill patients at emergency department.

Am J Emerg Med 2021 Jun 8;49:153-157. Epub 2021 Jun 8.

Emergency Department, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, PR China. Electronic address:

Objective: Copeptin, reflecting vasopressin release, as well as the National Early Warning Score (NEWS), reflecting the severity of critical illness, might qualify for survival prediction in elderly patients with critical illness. This prospective observational study aims at assessing the predictive value of copeptin combined with NEWS on the prognosis of elderly critical ill patients at emergency department (ED).

Methods: We analyzed serum copeptin levels and the NEWS at admission to the ED in a prospective, single-center, and observational study comprising 205 elderly patients with critical illness. Read More

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Use of available crop by-products as alternative bedding materials to wheat straw for rearing broilers.

Animal 2021 Jun 8;15(7):100260. Epub 2021 Jun 8.

Poultry Production Department, Agriculture College, Damietta University, Damietta 34517, Egypt.

The provision of suitable bedding for rearing broilers is an ongoing challenge for poultry producers. The aim of the present study was to evaluate the effect of using different types of crop residues as alternative bedding materials to wheat straw on growth performance, carcass traits, health, and welfare of broilers; moreover, the effects on the bedding and air quality were analyzed. We randomly assigned 180 1-day-old chickens (Cobb 500) across six bedding groups (three replicates of 10 birds each). Read More

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Altered neuroaxonal integrity in schizophrenia and major depressive disorder assessed with neurofilament light chain in serum.

J Psychiatr Res 2021 Jun 2;140:141-148. Epub 2021 Jun 2.

Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zürich, University of Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.

Background: Schizophrenia (SZ) and major depressive disorders (MDD) have been frequently linked to anatomical brain alterations. However, the relationship between brain pathology, inflammation and clinical symptoms in these disorders is still unclear. Thus, by applying novel blood markers of neuroaxonal integrity such as neurofilament light chain (NfL), we can now address main issues in psychiatric research and potentially offer innovative diagnostic tools toward better clinical characterizations and monitoring in both SZ and MDD. Read More

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Reliability, validity, and maturation-related differences of frontal and sagittal plane landing kinematic measures during drop jump and tuck jump screening tests in male youth soccer players.

Phys Ther Sport 2021 May 28;50:206-216. Epub 2021 May 28.

Department of Physical Activity and Sport, Faculty of Sport Sciences, Campus of Excellence Mare Nostrum, University of Murcia, Murcia, Spain; Sports and Musculoskeletal System Research Group (RAQUIS), University of Murcia, Murcia, Spain.

Objectives: To determine the inter-rater and intra-rater reliability of frontal and sagittal plane landing kinematic measures during drop jump (DVJ) and tuck jump (TJA) tasks in male youth soccer players, to assess the concurrent validity between DVJ and TJA tests, and to evaluate the ability of both tasks to detect differences between players' stage of maturation.

Design: Cross-sectional study.

Participants: 223 male youth soccer players. Read More

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4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors.

Bioorg Chem 2021 May 26;113:105024. Epub 2021 May 26.

Institut des Biomolécules Max Mousseron, UMR5247 CNRS, Université de Montpellier, ENSCM, Faculté de Pharmacie, 34093 Montpellier Cedex 5, France. Electronic address:

In Gram-negative bacteria, the major mechanism of resistance to β-lactam antibiotics is the production of one or several β-lactamases (BLs), including the highly worrying carbapenemases. Whereas inhibitors of these enzymes were recently marketed, they only target serine-carbapenemases (e.g. Read More

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Toxicologic effect and transcriptome analysis for short-term orally dosed enrofloxacin combined with two veterinary antimicrobials on rat liver.

Ecotoxicol Environ Saf 2021 Jun 8;220:112398. Epub 2021 Jun 8.

College of Veterinary Medicine, China Agricultural University, Beijing 100193, China; Beijing Key Laboratory of Animal-derived Food Safety Testing Technology, Beijing 100193, China; Chinese National Reference Laboratory for Veterinary Drug Residues, Beijing 100193, China. Electronic address:

Presently, toxicological assessment of multiple veterinary antimicrobials has not been performed on mammals. In this study, we assessed the short-term toxicity of enrofloxacin (E) combined with colistin (C) and quinocetone (Q). Young male rats were orally dosed drug mixtures and single drugs in 14 consecutive days, each at the dose of 20, 80, and 400 mg/(kg·BW) for environmental toxicologic study. Read More

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Medial olivary complex reflex in term newborns with hyperbilirubinemia.

Int J Pediatr Otorhinolaryngol 2021 May 21;147:110777. Epub 2021 May 21.

Dept. of Otolaryngology, Faculty of Medicine, Baskent University, Ankara, Turkey.

Objective: This study aimed to compare the integrity of the efferent auditory pathways of newborns that had high hyperbilirubinemia levels and required treatment due to these and healthy newborns.

Methods: Term-born (37 weeks or later) infants that were brought to the Newborn Polyclinic of the Başkent University Hospital were included in the study. The study included a total of 84 infants including healthy newborns (n = 42) and those that had jaundice and were receiving phototherapy (n = 42). Read More

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Environmental risks related to organic compounds from the combustion of paper briquettes in domestic boilers.

J Hazard Mater 2021 Jun 2;418:126291. Epub 2021 Jun 2.

Centre ENET - Energy Units for Utilization of Non-Traditional Energy Sources, VŠB - Technical University of Ostrava, 17. listopadu 15/2172, 708 00 Ostrava-Poruba, Czech Republic. Electronic address:

Environmental risks connected with the combustion of paper/cardboard briquettes are still not sufficiently known. This paper aims to bring attention to the risks related to the utilisation of paper briquettes in local boilers and to characterise these risks by means of the identification of organic compounds in deposits from exhaust flues. The identification of the chemical compounds was performed by pyrolysis gas chromatography with mass spectrometric detection. Read More

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CtNorm: Real time PCR cycle of threshold (Ct) normalization algorithm.

Amin Ramezani

J Microbiol Methods 2021 Jun 8:106267. Epub 2021 Jun 8.

Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Science, Shiraz, Iran; Department of Medical Biotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

In relative quantification with Real Time PCR (qRT-PCR,), accurate analysis requires equal amplification efficiency for both genes (Gene of interest and reference gene) and equal threshold values for all the samples. In this quantification method the expression level in treated samples will be calculated in comparison to the control group. We conducted the present study to design an algorithm for converting the data obtained from different runs containing identical standard samples into one run with the same amplification efficiency and threshold value. Read More

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Prognostic significance of preoperative haemoglobin A1c level in patients with lung adenocarcinoma.

Interact Cardiovasc Thorac Surg 2021 Jun 11. Epub 2021 Jun 11.

Department of Thoracic Surgery, Hyogo Cancer Center, Akashi, Japan.

Objectives: We investigated the influence of the preoperative haemoglobin A1c (HbA1c) value on the prognosis and pathology of patients with lung adenocarcinoma who underwent surgery.

Methods: We reviewed the medical records of 400 lung adenocarcinoma patients who underwent lobectomy with mediastinal lymph node dissection between 2009 and 2013 using a prospectively maintained database. We stratified 400 patients into 4 groups according to the preoperative HbA1c value as follows: HbA1c ≤ 5. Read More

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Epidermal growth factor as a potential prognostic and predictive biomarker of response to platinum-based chemotherapy.

PLoS One 2021 11;16(6):e0252646. Epub 2021 Jun 11.

Laboratorium of Experimental Medicine and Pediatrics and Member of the Infla-Med Centre of Excellence, University of Antwerp, Antwerp, Belgium.

In this study, we investigated serum epidermal growth factor (EGF) in an oncological population of head- and neck and pulmonary neoplasms and whether serum EGF could serve as a prognostic marker of survival and as a predictive marker for treatment response to platinum-based chemotherapy. A total of 59 oncological patients and a control group of age- and sex-matched healthy volunteers were included in this study. Pre-treatment serum EGF from both groups was determined. Read More

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Making voluntary medical male circumcision services sustainable: Findings from Kenya's pilot models, baseline and year 1.

PLoS One 2021 11;16(6):e0252725. Epub 2021 Jun 11.

National STD/AIDS Control Program (NASCOP), Ministry of Health, Nairobi, Kenya.

Voluntary medical male circumcision is a crucial HIV prevention program for men in sub-Saharan Africa. Kenya is one of the first countries to achieve high population coverage and seek to transition the program to a more sustainable structure designed to maintain coverage while making all aspects of service provision domestically owned and implemented. Using pre-defined metrics, we created and evaluated three models of circumcision service delivery (static, mobile and mixed) to identify which had potential for sustaining high circumcision coverage among 10-14-year-olds group, a historically high-demand and accessible age group, at the lowest possible cost. Read More

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Zirconium and Aluminum MOFs for Low-Pressure SO Adsorption and Potential Separation: Elucidating the Effect of Small Pores and NH Groups.

ACS Appl Mater Interfaces 2021 Jun 11. Epub 2021 Jun 11.

Institut für Anorganische Chemie und Strukturchemie, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, 40225 Düsseldorf, Germany.

Finding new adsorbents for the desulfurization of flue gases is a challenging task but is of current interest, as even low SO emissions impair the environment and health. Four Zr- and eight Al-MOFs (Zr-Fum, DUT-67(Zr), NU-1000, MOF-808, Al-Fum, MIL-53(Al), NH-MIL-53(Al), MIL-53(tdc)(Al), CAU-10-H, MIL-96(Al), MIL-100(Al), NH-MIL-101(Al)) were examined toward their SO sorption capability. Pore sizes in the range of about 4-8 Å are optimal for SO uptake in the low-pressure range (up to 0. Read More

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Effect of a sonic toothbrush on the abrasive dentine wear using toothpastes with different abrasivity values.

Int J Dent Hyg 2021 Jun 11. Epub 2021 Jun 11.

Department of Preventive Dentistry and Oral Epidemiology, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.

Objective: This in-vitro study aimed to investigate the effect of a sonic toothbrush on the resulting abrasive dentine wear using toothpastes with different abrasivities compared to the use of a manual toothbrush.

Methods: Ninety-six bovine dentine samples were divided into six groups and subjected to brushing sequence (sonic: 20 min, 0.9 N, 10 strokes/min, manual: 20 min, 1. Read More

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Cu, Ni, and Zn effects on basic physiological and stress parameters of Raphidocelis subcapitata algae.

Environ Sci Pollut Res Int 2021 Jun 11. Epub 2021 Jun 11.

Department of Environmental Ecology, Faculty of Natural Sciences, Comenius University in Bratislava, Ilkovičova 6, 842 15, Bratislava, Slovak Republic.

The submitted work observed Cu, Ni, and Zn effects on selected physiological and stress parameters of the alga Raphidocelis (Pseudokirchneriella) subcapitata. In 96-h experiments, EC50 values for algal specific growth rates (SGR) inhibition in Cu, Ni, and Zn presence were estimated as 0.15, 0. Read More

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The diagnostic utility of size and apparent diffusion coefficient values for cervical lymph nodes in patients with osteomyelitis of the jaw bone.

Oral Radiol 2021 Jun 11. Epub 2021 Jun 11.

Department of Radiology, Nihon University School of Dentistry At Matsudo, 2-870-1 Sakaecho-Nishi, Matsudo, Chiba, 271-8587, Japan.

Purpose: The purpose of this study was to (1) clarify the size and apparent diffusion coefficient (ADC) value of lymph nodes (LN) in each state in their quantitative evaluation diffusion-weighted imaging, and (2) to determine the diagnostic utility of size and ADC values in the quantitative evaluation of LNs using diffusion-weighted imaging.

Methods: This was a retrospective cohort study at our hospital conducted between April 2017 and March 2019. A total of 50 patients (20 men, 30 women) with 118 LNs, aged 34-90 years (mean age 61. Read More

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Mineralogy, geochemistry, C and O isotopic characteristics of urinary stones in Iran, a case study of Lorestan Province.

Environ Geochem Health 2021 Jun 11. Epub 2021 Jun 11.

Department of Environment, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran.

Owing to the importance of urinary stones as one of the biominerals in the human body, it is necessary to investigate their chemical composition and mineralogy. In this matter, a mineralogical study using X-ray diffraction and scanning electron microscopy indicated that urinary stones in Lorestan Province were divided into 5 groups of calcium oxalate, urate, cysteine, phosphate and mixed stones (Whewellite, uric acid, phosphate). In this regard, the microscopic studies revealed that Whewellite was the most important mineral phase among various phases. Read More

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Consistent scaling of whole-shoot respiration between Moso bamboo (Phyllostachys pubescens) and trees.

J Plant Res 2021 Jun 11. Epub 2021 Jun 11.

Department of Agro-environmental Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, 080-8555, Japan.

Both Moso bamboo (Phyllostachys pubescens) and tree forests have a large biomass; they are considered to play an important role in ecosystem carbon budgets. The scaling relationship between individual whole-shoot (i.e. Read More

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Effects of Different Bone Substitutes on Reactive Oxygen Species Release in Leukocytes in Vitro: A Pilot Study.

Int J Oral Maxillofac Implants 2021 May-Jun;36(3):e42-e50

Purpose: To evaluate the formation of reactive oxygen species in human leukocytes promoted by bone substitutes that are different in origin and morphology used for jawbone tissue regeneration.

Materials And Methods: This preclinical prospective randomized crossover study involved 10 subjects, from whom venous blood samples were taken. Leukocytes were separated and standardized. Read More

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Dynamic Gait Parameters in Patients with Nonunion of the Tibia Following Treatment with the Ilizarov Method.

J Biomech Eng 2021 Jun 10. Epub 2021 Jun 10.

al. Witosa 26,Opole, Poland Wroclaw,, 45-401 Poland.

Introduction: The purpose of this study was a comprehensive assessment of the dynamic parameters of gait in patients who underwent Ilizarov treatment for nonunion of the tibia.

Materials And Methods: The experimental group consisted of24 individuals treated with the Ilizarov method for nonunion of the tibia.The control group comprised31healthy individuals,matched for BMI,sex,and age. Read More

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Correlation of medial longitudinal arch morphology with body characteristics and locomotive function in community-dwelling older women: A cross-sectional study.

J Orthop Surg (Hong Kong) 2021 May-Aug;29(2):23094990211015504

School of Rehabilitation, Osaka Kawasaki Rehabilitation University, Osaka, Japan.

Purpose: This cross-sectional study aimed to investigate the effects of foot arch deformities on physical characteristics, muscular strength, and motor function in older women depending on the presence or absence of pain.

Methods: Overall, 145 community-dwelling women aged 65 to 90 years were included in this study. We measured the foot arch height ratio (AHR, dorsal height/truncated foot length) and classified participants with AHR values above, below, or within 1. Read More

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Arterial Stiffness Assessed by Cardio-Ankle Vascular Index in Patients With Abdominal Aortic Aneurysm and Its Alterations After Treatment.

Vasc Endovascular Surg 2021 Jun 11:15385744211023281. Epub 2021 Jun 11.

Department of Vascular Surgery, Medical School, 68989University of Athens, Athens, Greece.

Purpose: The aim of the present study was to investigate a potential difference on the arterial stiffness among aneurysm patients and non-aneurysm controls, as well as to explore potential changes between patients treated either with endovascular or open repair.

Materials And Methods: A 110 patients with an infrarenal AAA were prospectively enrolled in this study. Fifty-six patients received an EVAR, whereas 54 patients received an open surgical repair. Read More

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Efficacy and Safety of Bioabsorbable Bone Hemostatic Agent in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial.

Clin Appl Thromb Hemost 2021 Jan-Dec;27:10760296211023589

Department of Orthopedic Surgery, 37990Seoul National University College of Medicine, Jongno-gu, Seoul, South Korea.

Although a bioabsorbable bone hemostatic agent (BBHA) was developed approximately 20 years ago to overcome the shortcomings of conventional bone wax, its bleeding control capacity has not yet been studied. This study was aimed at investigating the efficacy and safety of BBHA in total knee arthroplasty (TKA). Sixty-two patients who underwent unilateral primary TKA for knee osteoarthritis were included and randomized to the control or BBHA group. Read More

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Electroacupuncture Pretreatment at Neiguan (PC6) attenuates autophagy in rats with myocardial ischemia reperfusion through the phosphatidylinositol 3-kinase-Akt-mammalian target of rapamycin pathway.

J Tradit Chin Med 2021 Jun;41(3):455-462

Institute of Internal medicine, Huangjiahu Hospital of Hubei University of Traditional Chinese Medicine, Wuhan 430065, China.

Objective: To investigate the protective efficacy of electroacupuncture (EA) pretreatment at Neiguan (PC6) on myocardial ischemia-reperfusion (I/R) in rats.

Methods: Fifty rats were randomly divided into five groups (n = 10): sham operation group, model group (underwent in vivo myocardial I/R), EA pretreatment group [EA at Neiguan (PC 6) 1 week before I/R], wortmannin group (1 week before I/R, the PI3K inhibitor, wortmannin, was injected), EA pretreatment + wortmannin group (both pretreatments were performed simultaneously). After establishing the I/R model, 2,3,5-triphenyltetrazolium chloride (TTC) staining was used to analyze the weight and area of the myocardial infarction tissue. Read More

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Effect of Rongchang capsule on seizure behavior, cognitive impairment, and hippocampal DNA damage and inflammatory factors in epileptic rat.

J Tradit Chin Med 2021 Jun;41(3):438-446

Department of pediatrics, Graduate School of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.

Objective: To observe the behavioral changes and changes in DNA fragments and related inflammatory factors in the hippocampus of epileptic rats pretreated with Rongchang capsule ().

Methods: Eighty Sprague-Dawley rats were randomly divided into the normal group (NG), model group (MG), sodium valproate group (VG), and Rongchang capsule group (RG) (n = 20 in each group). Pentylentetrazol was administered to the MG, VG, and RG to induce epilepsy. Read More

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Untargeted metabolomics analysis by gas chromatography/time-of-flight mass spectrometry of human serum from methamphetamine abusers.

Addict Biol 2021 Jun 10:e13062. Epub 2021 Jun 10.

School of Food Science, State Key Laboratory of Food Science and Technology, National Engineering Research Center for Functional Foods, School of Food Science Synergetic Innovation Center of Food Safety and Nutrition, Joint International Research Laboratory on Food Safety, Jiangnan University, Wuxi, China.

Methamphetamine (METH) abuse has become a global public health problem. However, the potential mechanisms involving METH-induced metabolic disorders have thus far remained poorly understood. Metabolomics can provide a clue for the cause of apparent changes and consequently be used to investigate the METH-induced dysregulation of metabolite expression and the mechanism of metabolic disorder mechanism. Read More

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Neurofilament light chain as a biomarker of meningoencephalitis of unknown etiology in dogs.

J Vet Intern Med 2021 Jun 10. Epub 2021 Jun 10.

Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.

Background: Neurofilament light chain (NfL) is a neuron-specific cytoskeletal protein expressed in axons. Damaged axons of the central nervous system release NfLs into the cerebrospinal fluid (CSF) and the blood. In humans with neurologic diseases, NfL is used as a biomarker. Read More

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Genetic basis of some physiological traits and yield in early and late sowing conditions in bread wheat (Triticum aestivum L.).

J Appl Genet 2021 Jun 10. Epub 2021 Jun 10.

Wheat Breeding Group, Plant Breeding and Genetics Division, Nuclear Institute for Agriculture and Biology, Jhang Road, Faisalabad, Pakistan.

The rise in human population necessitates the use of all available tools to enhance wheat productivity. In this regard, pre-breeding has mobilized novel underutilized genetic variation into breeding programs. However, this germplasm needs to be characterized for its efficient utilization. Read More

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Administration of Silver Nanoparticles in Diabetes Mellitus: A Systematic Review and Meta-analysis on Animal Studies.

Biol Trace Elem Res 2021 Jun 10. Epub 2021 Jun 10.

Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Biological features of silver nanoparticles in rising the insulin level of diabetic animal models were considered in recent years, which resulted in decreasing hyperglycemia condition. We reviewed the published literature to investigate the possible role of silver nanoparticles (Ag-NPs) throughout the treatment of diabetes mellitus in animal studies. In this systematic review and meta-analysis, we performed a search throughout the English literature of electronic databases, including Scopus, PubMed, and ISI Web of Science, up to the date of May 22, 2020. Read More

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