AJOG Glob Rep 2021 Feb 27;1(1). Epub 2021 Jan 27.
Department of Obstetrics/Gynecology, Thomas Jefferson University, Philadelphia, PA (Drs Short and Derman); Department of Obstetrics and Gynecology, Christiana Care, Newark, DE (Dr Hoffman); KLE Academy of Higher Education and Research Jawaharlal Nehru Medical College, Belagavi, Karnataka, India (Drs Metgud, Kavi, and Goudar); Kinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo (Drs Okitawutshu and Tshefu); University of North Carolina at Chapel Hill, Chapel Hill, NC (Dr Bose); University Teaching Hospital, Lusaka, Zambia (Drs Mwenechanya and Chomba); Department of Obstetrics/Gynecology, University of Alabama at Birmingham, Birmingham, AL (Dr Carlo); Instituto de Nutrición de Centro América y Panamá, Guatemala City, Guatemala (Drs Figueroa and Garces); University of Colorado School of Medicine, Aurora, CO (Dr Krebs); Aga Khan University, Karachi, Pakistan (Drs Jessani and Saleem); Department of Obstetrics/Gynecology, Columbia University, New York, NY (Dr Goldenberg); Lata Medical Research Foundation, Nagpur, India (Drs Das and Patel); Department of Global Health, Boston University School of Public Health, Boston, MA (Dr Hibbert); Department of Child Health and Paediatrics, Moi University School of Medicine, Eldoret, Kenya (Ms Achieng, Mr Nyongesa, and Dr Esamai); Indiana University School of Medicine, Indianapolis, IN (Dr Bucher); Research Triangle Institute International, Research Triangle Park, NC (Ms Nowak); Social, Statistical and Environmental Health Sciences, Research Triangle Institute International, Research Triangle Park, NC (Mr Goco, and Drs Nolen and McClure); Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD (Drs Koso-Thomas and Miodovnik).
Background: The daily use of low-dose aspirin may be a safe, widely available, and inexpensive intervention for reducing the risk of preterm birth. Data on the potential side effects of low-dose aspirin use during pregnancy in low- and middle-income countries are needed.
Objective: This study aimed to assess differences in unexpected emergency medical visits and potential maternal side effects from a randomized, double-blind, multicountry, placebo-controlled trial of low-dose aspirin use (81 mg daily, from 6 to 36 weeks' gestation). Read More