141,556 results match your criteria vaginal

Induction of labour as compared with spontaneous labour in low-risk women: A multicenter study in Catalonia.

Sex Reprod Healthc 2021 Jul 26;29:100648. Epub 2021 Jul 26.

School of Health Sciences Blanquerna, Universitat Ramon Llull, Carrer Padilla 326, 08025 Barcelona, Spain; Catalan Health Service, Government of Catalonia, Travessera de les Corts 131, 08028 Barcelona, Spain. Electronic address:

Objective: To compare birth and neonatal outcomes in low-risk women undergoing induced labour with those undergoing spontaneous onset.

Methods: This retrospective multicentre study included 30 public maternity hospitals in Catalonia between 2016 and 2017. The study population consisted of 5,717 women. Read More

View Article and Full-Text PDF

Neonatal morbidity and mortality by mode of delivery in very preterm neonates.

Am J Obstet Gynecol 2021 Jul 28. Epub 2021 Jul 28.

Washington University in St. Louis, Division of Maternal Fetal Medicine; Hadassah University Medical Center, Jerusalem, Israel.

Background: The safest mode of delivery for very preterm infants is an ongoing topic of debate. There are many reasons for cesarean delivery (CD) in extremely preterm and very preterm infants, including labor, fetal distress, maternal indications, and malpresentation.

Objectives: This study aimed to determine whether CD is associated with significantly improved neonatal morbidity. Read More

View Article and Full-Text PDF

Group B Streptococcus Colonisation, Prevalence, Associated Risk Factors and Antimicrobial Susceptibility Pattern Among Pregnant Women Attending Antenatal Care at Dschang District Hospital, West Region of Cameroon: A hospital-based Cross-Sectional Study.

Int J Clin Pract 2021 Jul 31:e14683. Epub 2021 Jul 31.

Research Unit of Microbiology and Antimicrobial Substances, Department of Biochemistry, University of Dschang, Cameroon.

Background: Group B Streptococcus (GBS), also known as Streptococcus agalactiae, is a Gram-positive bacterium known for its ability to colonise the vaginal and rectal areas of the mother and is a leading cause of neonatal mortality and morbidity. This study aimed at determining the prevalence, associated risk factors and antimicrobial susceptibility of GBS colonization among pregnant women attending antenatal Care (ANC) at Dschang District Hospital.

Methods: This hospital-based cross-sectional study used a multistage sampling method to recruit a total of 621 consented pregnant women who attended ANC in Dchang District Hospital. Read More

View Article and Full-Text PDF

The relation between cigarette smoking with delivery outcomes. An evaluation of a database of more than nine million deliveries.

J Perinat Med 2021 Jul 30. Epub 2021 Jul 30.

Division of Reproductive Endocrinology and Infertility, McGill University Health Care Center, Montreal, QC, Canada.

Objectives: Smoking in pregnancy is associated with an increased risk of preterm birth (PTB), intrauterine growth restriction, placental abruption and perinatal death. The association between smoking and other delivery outcomes, such as chorioamnionitis, mode of delivery or post partum hemorrhage (PPH), however, is insufficient as only few studies addressed these issues. The aim of the study was to evaluate the association between prenatal smoking and delivery outcomes in a large database, while controlling for confounding effects. Read More

View Article and Full-Text PDF

Is there agreement between the preference of examiner and women for unidigital and bidigital vaginal palpation? A qualitative study.

Int Urogynecol J 2021 Jul 30. Epub 2021 Jul 30.

Women's Health Research Laboratory, Physical Therapy Department, Federal University of São Carlos, Rodovia Washington Luís, km 235, Monjolinho, São Carlos, SP, 13565-905, Brazil.

Introduction And Hypothesis: The International Continence Society recommends vaginal palpation as a method for assessing pelvic floor muscle (PFM) function. Our aim was to analyze the agreement between preferences of examiner and participants according to unidigital and bidigital vaginal palpation during PFM assessment. The second aim was to investigate qualitatively women's perception of vaginal palpation. Read More

View Article and Full-Text PDF

Short term complications in mesh augmented vaginal repair of pelvic organ prolapse are not higher when compared with native tissue repair.

Int Urogynecol J 2021 Jul 30. Epub 2021 Jul 30.

Department of Obstetrics and Gynecology, Division of Urogynecology and Pelvic Reconstructive Surgery, The Ottawa Hospital, Ottawa, ON, Canada.

Introduction And Hypothesis: Accumulating evidence regarding the negative long-term consequences of transvaginal mesh-based procedures for pelvic organ prolapse has led to a sharp decline in mesh-based procedures. We aimed to evaluate the short-term complications of mesh-based procedures for carefully selected patients with pelvic organ prolapse after Food and Drug Administration warnings.

Methods: A retrospective database review of the ACS NSQIP database was completed to examine 30-day complications including re-operation, prolonged length of stay, blood transfusion, surgical site infection, urinary tract infection, readmission and wound dehiscence in mesh-augmented and native tissue-based transvaginal procedures for pelvic organ prolapse. Read More

View Article and Full-Text PDF

A case of neovagina surgical creation using the uterine cervix remnant in a patient with Mayer-Rokitansky-Küster-Hauser syndrome.

Fertil Steril 2021 Jul 27. Epub 2021 Jul 27.

Limited Liability Company "Clinika Doktora Medvedeva", Dnipro, Ukraine.

Objective: To study the efficacy of a novel approach to vaginoplasty in a patient with vaginal aplasia and a preserved cervix.

Design: We present the case of a 28-year-old patient who was referred with a history of absent menstruation and vaginal intercourse was absent as well as abnormal development of the internal genitals. The patient underwent a laparoscopic cystectomy in 2012 because of an ovarian cyst and later that year underwent laparotomic supracervical hysterectomy with bilateral salpingectomy because of severe pain caused by a hematometra in their uterine remnant. Read More

View Article and Full-Text PDF

Update on Italian-validated questionnaires for pelvic floor disorders.

Minerva Obstet Gynecol 2021 Jul 30. Epub 2021 Jul 30.

Department Obstetrics and Gynaecology EOC - Beata Vergine Hospital, Mendrisio, Switzerland.

Objectives: Pelvic floor disorders (PFDs), which include urinary incontinence, pelvic organ prolapse, sexual dysfunction and gastrointestinal disorders, affect over 20% of the adult population. Prevalence may also be underestimated, since a certain portion of patients may be reluctant to talk to physicians about PFDs due to embarassment. Consequently, there is a need for self-assessed diagnostic tools with the capability to screen population and collect clinical information. Read More

View Article and Full-Text PDF

Should we inform women about the recognised risks of childbirth?

Aust N Z J Obstet Gynaecol 2021 Jul 30. Epub 2021 Jul 30.

Department of Colorectal Surgery, St Vincent's Hospital, Sydney, Australia.

Background: At present in Australia women are not routinely, systematically informed of the risks of childbirth.

Aims: It is hoped this presentation of the perspective of some women who suffer unexpected obstetric complications will encourage change.

Materials And Methods: The experience of women involved in obstetric medicolegal reports prepared by a colorectal surgeon over ten years is analysed. Read More

View Article and Full-Text PDF

[Advances in the use of lactic acid bacteria as mucosal delivery vectors of therapeutic molecules].

Zhu Zeng

Sheng Wu Gong Cheng Xue Bao 2021 Jul;37(7):2272-2282

College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, China.

Lactic acid bacteria (LAB) are generally recognized as safe food-grade microorganisms and are widely used in food production, preservation, and as probiotics to promote human health. Given the need to develop effective drug delivery strategies, LAB have become attractive live vehicles for the oral, intranasal and vaginal delivery of therapeutic molecules. Being live and safe organisms, LAB are able to directly produce and deliver target proteins for therapeutic purpose, which remarkably reduces the cost for drug production. Read More

View Article and Full-Text PDF

Nonablative, Noncoagulative Multipolar Radiofrequency and Pulsed Electromagnetic Field Treatment Improves Vaginal Laxity and Sexual Function.

Womens Health Rep (New Rochelle) 2021 27;2(1):285-294. Epub 2021 Jul 27.

Association of Laser Medicine and Cosmetology, Cogerent Laser Clinic, Kyiv, Ukraine.

This study investigated nonablative/noncoagulative multipolar radiofrequency and pulsed electromagnetic field (RF/PEMF) treatment for vaginal laxity (VL) and its impact on sexual function in parous women. This prospective, open-label single-center study enrolled 34 female subjects, 23-59 years of age, with ≥1 vaginal delivery and self-reported VL. Three monthly intravaginal treatments with RF/PEMF energy were performed. Read More

View Article and Full-Text PDF

Ureaplasma parvum alters the immune tolerogenic state in placental tissue and could cause miscarriage.

Fertil Steril 2021 Jul 26. Epub 2021 Jul 26.

Microbiology and Immunology Laboratory, Federal University of Bahia, Anísio Teixeira Campus, Vitória da Conquista, Brazil. Electronic address:

Objective: To study the inflammatory profile and genes involved in the response to bacterial infections in women who developed spontaneous abortion in the presence of Ureaplasma parvum.

Design: Cross-sectional study.

Setting: A maternal and child referral center. Read More

View Article and Full-Text PDF

Vedolizumab combined with surgical resection successfully treated perforating Crohn's disease with peritoneal space to rectal and vaginal fistulas: a case report.

BMC Gastroenterol 2021 Jul 29;21(1):299. Epub 2021 Jul 29.

Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou Branch, Chang Gung University College of Medicine, 5, Fu-Hsin Street, Guei-Shan District, Taoyuan City, 33305, Taiwan.

Background: Intestinal perforations and fistulas are common complications of Crohn's disease. However, chronic perforation with peritoneal space to rectal and vaginal fistulas have not been previously reported.

Case Presentation: A 38-year-old female suffered from progressive lower abdominal pain, diarrhea and weight loss. Read More

View Article and Full-Text PDF

Impact of domestic violence against pregnant women in Minia governorate, Egypt: a cross sectional study.

BMC Pregnancy Childbirth 2021 Jul 29;21(1):535. Epub 2021 Jul 29.

Department of Obstetrics and Gynecology, Faculty of Medicine, Minia University, Minia, 61511, Egypt.

Background: Domestic violence is a common problem that is related to many serious short-term and long-term health hazards around the world.

Methods: During obtaining the medical history from the participants, the questions used to assess the abuse were derived from the widely used Abuse Assessment Screen (AAS). Potential risk factors including a variety of socio-demographic and reproductive health-relation indicators were assessed. Read More

View Article and Full-Text PDF

The efficacy and safety of MR-HIFU and US-HIFU in treating uterine fibroids with the volume <300 cm: a meta-analysis.

Int J Hyperthermia 2021 ;38(1):1126-1132

Department of Gynecology, Jiangsu Province Hospital, Nanjing, China.

Background: High-intensity focused ultrasound (HIFU) is a promising and non-invasive therapy for symptomatic uterine fibroids. Currently, the main image-guided methods for HIFU include magnetic resonance-guided (MR-HIFU) and ultrasound-guided (US-HIFU). However, there are few comparative studies on the therapeutic efficacy and safety of MR-HIFU and US-HIFU in treating symptomatic uterine fibroids with a volume <300 cm. Read More

View Article and Full-Text PDF
January 2021

Predictive models to identify Holstein cows at risk of metritis and clinical cure and reproductive/productive failure following antimicrobial treatment.

Prev Vet Med 2021 Jul 13;194:105431. Epub 2021 Jul 13.

Department of Large Animal Clinical Sciences, University of Florida, Gainesville, 32610, USA; Department of Animal Sciences, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, 32610, USA. Electronic address:

Precision dairy farming, specifically the design of management strategies according to the animal's needs, may soon become the norm since automated technologies that generate large amounts of data for each individual are becoming more affordable. Our objectives were to determine whether the use of behavioral changes could improve the accuracy of prediction of the risk of metritis and the risk of clinical cure of cows diagnosed with metritis. Addition of behavioral data to the algorithms to predict the outcomes of interest increased their accuracy by 7 to 32%. Read More

View Article and Full-Text PDF

Has the prevalence of levator avulsion after forceps delivery changed over the last six decades? A retrospective study in a urogynaecological population.

Eur J Obstet Gynecol Reprod Biol 2021 Jul 14;264:184-188. Epub 2021 Jul 14.

Sydney Medical School Nepean, University of Sydney, Penrith, NSW, Australia.

Objective: Forceps delivery is associated with a higher risk of maternal birth trauma. It is speculated that it is due to sub-optimal use of forceps in inexperienced hands. The aim of this study was to determine the association between time of forceps birth and prevalence of levator avulsion over the last six decades. Read More

View Article and Full-Text PDF

Vaginal estrogen and association with dementia: A nationwide population-based study.

Alzheimers Dement 2021 Jul 28. Epub 2021 Jul 28.

Department of Gynaecology, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Introduction: Use of systemic hormone therapy has been positively associated with development of dementia. Little is known about the dose-dependent effect of vaginal estradiol on dementia risk.

Methods: We assessed associations between cumulative dose of vaginal estradiol tablets and dementia in a case-control study nested in a nationwide Danish cohort of women aged 50 to 60 years at study initiation, who did not use systemic hormone therapy. Read More

View Article and Full-Text PDF

Congenital Pouch Colon: Case Series and Review of Evidences for Resection.

J Indian Assoc Pediatr Surg 2021 May-Jun;26(3):153-161. Epub 2021 May 17.

Department of Salute della Donna e del Bambino, Division of Pediatric Surgery, University of Padova, Padova, Italy.

Background: Congenital pouch colon (CPC) is a rare variant of anorectal malformations (ARM) with its highest reported incidence in India. We aimed to describe five patients affected by CPC, in which the tissue from the terminal dilated colon has been successfully used and to discuss our results on the light of an extended revision of the literature.

Materials And Methods: The clinical details of five cases treated for CPC in two Italian Centers were retrospectively reviewed assessing the fate of the terminal dilated colon. Read More

View Article and Full-Text PDF

A Clinicopathological Diagnostic and Therapeutic Approach to Cytolytic Vaginosis: An Extremely Rare Entity that may Mimic Vulvovaginal Candidiasis.

J Cytol 2021 Apr-Jun;38(2):88-93. Epub 2021 May 8.

Ege University Medical Faculty, Department of Gynecology and Obstetrics, Izmir, Turkey.

Objectives: Cytolytic vaginosis is a very rare entity that may be clinically misdiagnosed as vulvovaginal candidiasis. The aim of this study was to determine the incidence of cytolytic vaginosis in patients displaying symptoms similar to vulvovaginal candidiasis and to develop a clinicopathological diagnostic and therapeutic approach.

Materials And Methods: In total, 3000 cervical smear samples were evaluated at our center between 2015 and 2018. Read More

View Article and Full-Text PDF

Mycoplasma Genitalium Infection is not Associated with Genital Tract Inflammation among Adolescent and Young Adult Women in Baltimore, Maryland.

Sex Transm Dis 2021 Jul 28. Epub 2021 Jul 28.

Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland Department of Pediatrics, Adolescent /Young Adult Medicine Division, Johns Hopkins University School of Medicine, Baltimore, Maryland Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland Immunology Training Program, Johns Hopkins School of Medicine Department of Medicine, Infectious Disease Division, Johns Hopkins University School of Medicine, Baltimore, Maryland Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Background: Mycoplasma genitalium (MG) is a prevalent sexually transmitted infection, but little is known about the associated inflammatory signatures in the genital tract of adolescents and young adult (AYA) women.

Methods: AYA women age 13 to 24 were recruited. Demographic information, sexual behavior history, and medical history were collected. Read More

View Article and Full-Text PDF

DEveloping Tests for Endometrial Cancer deTection (DETECT): protocol for a diagnostic accuracy study of urine and vaginal samples for the detection of endometrial cancer by cytology in women with postmenopausal bleeding.

BMJ Open 2021 Jul 28;11(7):e050755. Epub 2021 Jul 28.

Division of Cancer Sciences, The University of Manchester, Manchester, UK

Introduction: Postmenopausal bleeding (PMB), the red flag symptom for endometrial cancer, triggers urgent investigation by transvaginal ultrasound scan, hysteroscopy and/or endometrial biopsy. These investigations are costly, invasive and often painful or distressing for women. In a pilot study, we found that voided urine and non-invasive vaginal samples from women with endometrial cancer contain malignant cells that can be identified by cytology. Read More

View Article and Full-Text PDF

Development and in vivo evaluation of chitosan-gel containing Mitracarpus frigidus methanolic extract for vulvovaginal candidiasis treatment.

Biomed Pharmacother 2020 Oct 14;130:110609. Epub 2020 Aug 14.

Bioactive Natural Products Laboratory and Protein Structure and Function Laboratory, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Campus, Juiz de Fora, MG, Brazil.

Vulvovaginal candidiasis (VVC) is characterized by inflammatory changes in the vaginal mucosa caused by abnormal colonization of Candida species. Traditional topical therapies using reference antifungal drugs usually present several issues and limitations for VVC treatment. Thus, the interest in new vaginal formulations, mainly those based on compounds from natural origin, has been growing over the last years. Read More

View Article and Full-Text PDF
October 2020

Coping with dyspareunia, the importance of inter and intrapersonal context on women's sexual distress: a population-based study.

Reprod Health 2021 Jul 28;18(1):161. Epub 2021 Jul 28.

Department of Reproductive Health, Tehran University of Medical Sciences, Tehran, Iran.

Background: Recently known as the genito-pelvic pain/penetration disorder (GPPPD), Dyspareunia is considered a negative factor affecting a couple's sexual health. This paper analyzes pain in Dyspareunia cases and determines protective factors causing lower levels of sexual distress among patients.

Methods: In a population-based cross-sectional study conducted in 2017, the cluster quota sampling technique was adopted to randomly select 590 Iranian married women aged 18-70 years from 30 health centers. Read More

View Article and Full-Text PDF

Outer membrane vesicles derived from Typhimurium can deliver 2a O-polysaccharide antigen to prevent 2a infection in mice.

Appl Environ Microbiol 2021 Jul 28:AEM0096821. Epub 2021 Jul 28.

Department of Medical Microbiology, School of Medicine, Nanchang University, Nanchang, China, 330006.

Shigellosis has become a serious threat to health in many developing countries due to the severe diarrhea it causes. 2a ( 2a) is the principal species responsible for this endemic disease. Despite multiple attempts to design a vaccine against shigellosis, no effective vaccine has not yet been developed. Read More

View Article and Full-Text PDF

detection in urogenital specimens from symptomatic and asymptomatic men and women using the cobas TV/MG test.

J Clin Microbiol 2021 Jul 28:JCM0026421. Epub 2021 Jul 28.

Louisiana State University Health Sciences Center, New Orleans, LA, USA.

is a prevalent sexually transmitted infection (STI). Diagnosis has historically relied on either microscopic analysis or culture, the latter being the previous gold standard. However, these tests are not readily available for male diagnosis, generally only perform well for symptomatic women, and are not as sensitive as nucleic acid amplification tests (NAATs). Read More

View Article and Full-Text PDF

Microbiota and epigenetics: promising therapeutic approaches?

Environ Sci Pollut Res Int 2021 Jul 28. Epub 2021 Jul 28.

Department of Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.

The direct/indirect responsibility of the gut microbiome in disease induction in and outside the digestive tract is well studied. These results are usually from the overpopulation of certain species on the cost of others, interaction with beneficial microflora, interference with normal epigenetic control mechanisms, or suppression of the immune system. Consequently, it is theoretically possible to cure such disorders by rebalancing the microbiome inside our bodies. Read More

View Article and Full-Text PDF

Risk factors for recurrence of pelvic organ prolapse after vaginal surgery among Ugandan women: a prospective cohort study.

Int Urogynecol J 2021 Jul 28. Epub 2021 Jul 28.

Department of Obstetrics and Gynecology, Makerere University College of Health Sciences, Kampala, Uganda.

Introduction And Hypothesis: This study was aimed at determining the recurrence rate and risk factors for the recurrence of pelvic organ prolapse (POP), at 1 year post-vaginal reconstructive surgery in a resource-limited setting.

Methods: We enrolled women who underwent vaginal surgery for POP at the urogynecology unit of Mbarara Regional Referral Hospital (MRRH) in southwestern Uganda between December 2018 and February 2020. The surgeries that were performed include anterior colporrhaphy for cystocele, posterior colporrhaphy for rectocele, vaginal hysterectomy with vault suspension for uterine prolapse, and cervicopexy in those with uterine prolapse where uterine-sparing surgery was desired. Read More

View Article and Full-Text PDF