15,960 results match your criteria vaccination rates

Characterization and purification of pentameric chimeric protein particles using asymmetric flow field-flow fractionation coupled with multiple detectors.

Anal Bioanal Chem 2021 Apr 10. Epub 2021 Apr 10.

C2P s.r.o. (NEXARS), The Campus Science Park, Palachovo náměstí 726/2, 625 00, Brno, Czech Republic.

Porcine circovirus causes the post-weaning multi-systemic wasting syndrome. Despite the existence of commercial vaccines, the development of more effective and cheaper vaccines is expected. The usage of chimeric antigens allows serological differentiation between naturally infected and vaccinated animals. Read More

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An Immune Recovery-Based Revaccination Protocol for Pediatric Hematopoietic Stem Cell Transplant Recipients: Revaccination Outcomes Following Pediatric HSCT.

Transplant Cell Ther 2021 Apr 28;27(4):317-326. Epub 2021 Jan 28.

Division of Pediatric Infectious Diseases, University of Colorado Anschutz Medical Campus and Children's Hospital Colorado, Aurora, Colorado.

Following hematopoietic stem cell transplant (HSCT), patients are at increased risk of vaccine-preventable diseases (VPDs) and experience worse outcomes of VPDs compared to immunocompetent patients. Therefore, patients are routinely vaccinated post-HSCT to restore VPD immunity. Published guidelines recommend revaccination based on time post-HSCT, although optimal revaccination timing and the value of using other clinical and laboratory variables to guide revaccination remain unclear. Read More

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SARS-CoV-2 presented moderately during two episodes of the infection with lack of antibody responses.

Virus Res 2021 Apr 6:198421. Epub 2021 Apr 6.

Clinical Research Department, Pasteur Institute of Iran, Tehran, Iran. Electronic address:

The world has gone through the critical phase of SARS-CoV-2 crisis caused by the new variants of the virus. The globally concerted effort to characterize viral genomic mutations across different clades has revealed several changes in the coding and also non-coding regions which might lead to a violent presentation or re-infection occurrence. Here, we studied a COVID-19 subject who represented the symptoms following the full recovery of the first infection. Read More

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Extended-spectrum beta-lactamase-producing strains among diarrheagenic Escherichia coli-prospective traveler study with literature review.

J Travel Med 2021 Apr 8. Epub 2021 Apr 8.

Department of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Background: Antibiotics are no longer the primary approach for treating all travelers' diarrhea (TD): most cases resolve without antibiotics and using them predisposes to colonization by multidrug-resistant bacteria. Data are accumulating on increasing resistance among TD pathogens, yet research into the most common agents, diarrheagenic Escherhichia coli (DEC), remains limited.

Methods: A total of 413 travelers to the (sub)tropics were analyzed for travel-acquired diarrheal pathogens and ESBL-PE. Read More

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Initial Effects of COVID-19 on Patients with ESKD.

J Am Soc Nephrol 2021 Apr 8. Epub 2021 Apr 8.

Chronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota.

Background: Reports from around the world have indicated a fatality rate of patients with coronavirus disease 2019 (COVID-19) in the range of 20%-30% among patients with ESKD. Population-level effects of COVID-19 on patients with ESKD in the United States are uncertain.

Methods: We identified patients with ESKD from Centers for Medicare and Medicaid Services data during epidemiologic weeks 3-27 of 2017-2020 and corresponding weeks of 2017-2019, stratifying them by kidney replacement therapy. Read More

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Are patients with rheumatic diseases on immunosuppressive therapies protected against preventable infections? A cross-sectional cohort study.

RMD Open 2021 Apr;7(1)

Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany.

Objective: To evaluate the prevalence of infections, prevalence of hospitalisation due to infections, the vaccination status and perceived screening of infections prior to the start of biologic disease modifying antirheumatic drugs (bDMARDs) of a patient cohort with chronic inflammatory rheumatic diseases (CIRD).

Methods: Consecutive CIRD patients reporting to our specialised centre were prospectively included (n=975) in this cross-sectional study. Data on comorbidities including infections, treatment, vaccination status, screening for latent tuberculosis infection (LTBI) and hepatitis B (HepB) were collected. Read More

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Public health practitioner perspectives on dealing with measles outbreaks if high anti-vaccination sentiment is present.

BMC Public Health 2021 04 9;21(1):578. Epub 2021 Apr 9.

Australian Centre for Health Engagement, Evidence & Values (ACHEEV), School of Health and Society, Faculty of the Arts, Social Sciences & Humanities, University of Wollongong, Northfields Ave, Wollongong, NSW, Australia.

Background: Communities with low vaccination rates are at greater risk during outbreaks of vaccine preventable diseases. Most Australian parents support vaccines, but some refuse and are often judged harshly by their community, especially during an outbreak. We sought the perspectives of Australian public health experts on the key issues faced when managing a measles outbreak in an area with high anti-vaccination sentiment. Read More

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T-B cell epitope peptides induce protective immunity against Mycoplasma pneumoniae respiratory tract infection in BALB/c mice.

Immunobiology 2021 Mar 24;226(3):152077. Epub 2021 Mar 24.

Institute of Pathogenic Biology, Hengyang Medical College, University of South China; Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control; Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang 421001, China. Electronic address:

Mycoplasma pneumoniae is the most common pathogen of community-acquired pneumonia in humans. Due to its high rates of antibiotic resistance, vaccination has become the best method to control the dissemination of M. pneumoniae. Read More

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Rubella and tick-borne encephalitis vaccination rates among staff and students at Austrian University of Applied Sciences.

Cent Eur J Public Health 2021 Mar;29(1):18-22

University of Applied Sciences Wiener Neustadt, Wiener Neustadt, Austria.

Objectives: Rubella and tick-borne encephalitis (TBE) are infectious diseases caused by viruses. Rubella is an air-borne infection. TBE, on the other hand, is transmitted by virus-infected ticks. Read More

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State of the Science: Screening, Surveillance, and Epidemiology of HPV-Related Malignancies.

Am Soc Clin Oncol Educ Book 2021 Mar;41:1-12

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.

Oropharyngeal, cervical, vulvar, and anal cancers share a common risk factor of HPV infection. HPV vaccination is currently recommended at age 11 or 12 to prevent new HPV infections for all genders with catch-up vaccination recommened up to age 26. Despite the known effectiveness of HPV vaccination to prevent HPV-related cancer, there is continued low uptake in the United States; only 40% of eligible persons were vaccinated in 2018, though rates are 70% among teenagers. Read More

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Single-dose BNT162b2 vaccine protects against asymptomatic SARS-CoV-2 infection.

Elife 2021 Apr 8;10. Epub 2021 Apr 8.

Department of Medicine, University of Cambridge, Cambridge, United Kingdom.

The BNT162b2 mRNA COVID-19 vaccine (Pfizer-BioNTech) is being utilised internationally for mass COVID-19 vaccination. Evidence of single-dose protection against symptomatic disease has encouraged some countries to opt for delayed booster doses of BNT162b2, but the effect of this strategy on rates of asymptomatic SARS-CoV-2 infection remains unknown. We previously demonstrated frequent pauci- and asymptomatic SARS-CoV-2 infection amongst healthcare workers (HCWs) during the UK's first wave of the COVID-19 pandemic, using a comprehensive PCR-based HCW screening programme (Rivett et al. Read More

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Cervical Cancer Screening Among Immigrant Women Residing in Australia: A Systematic Review.

Asia Pac J Public Health 2021 Apr 8:10105395211006600. Epub 2021 Apr 8.

The University of Queensland, Woolloongabba, Queensland, Australia.

Since the introduction of systematic population-based cervical cancer screening in Australia in 1991, age-standardized incidence of cervical cancer has halved. Given recent advances in human papillomavirus (HPV) vaccination and screening, cervical cancer may be eliminated nationally within 20 years. However, immigrant women are not equitably reached by screening efforts. Read More

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Relationship Between Influenza, Temperature, and Type 1 Myocardial Infarction: An Ecological Time-Series Study.

J Am Heart Assoc 2021 Apr 8:e019608. Epub 2021 Apr 8.

Clinical Pharmacology Unit Hospital Universitario Príncipe de Asturias Alcalá de Henares Madrid Spain.

Background Previous studies investigating the relationship of influenza with acute myocardial infarction (AMI) have not distinguished between AMI types 1 and 2. Influenza and cold temperature can explain the increased incidence of AMI during winter but, because they are closely related in temperate regions, their relative contribution is unknown. Methods and Results The temporal relationship between incidence rates of AMI with demonstrated culprit plaque (type 1 AMI) from the regional primary angioplasty network and influenza, adjusted for ambient temperature, was studied in Madrid region (Spain) during 5 influenza seasons (from June 2013 to June 2018). Read More

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The moderating effect of autonomy on promotional health messages encouraging healthcare professionals' to get the influenza vaccine.

J Exp Psychol Appl 2021 Apr 8. Epub 2021 Apr 8.

Department of Management.

Rates of flu vaccination among healthcare professionals often remain lower than recommended guidelines. We tested whether autonomy-supportive communication styles could improve the effectiveness of statements seeking to promote professionals' flu vaccination uptake. A pilot study established that statements presented in an autonomy-supportive communication style (i. Read More

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Determinants of COVID-19 vaccine acceptance in a high infection-rate country: a cross-sectional study in Russia.

Pharm Pract (Granada) 2021 Jan-Mar;19(1):2276. Epub 2021 Mar 22.

Department of Chemistry, College of Natural Sciences, Can Tho University. Can Tho (Vietnam).

Background: COVID-19 vaccine development is proceeding at an unprecedented pace. Once COVID-19 vaccines become widely available, it will be necessary to maximize public vaccine acceptance and coverage.

Objective: This research aimed to analyze the predictors of COVID-19 vaccine acceptance in Russia. Read More

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Rabies vaccination and multiple sclerosis relapse: A retrospective cohort study.

Mult Scler Relat Disord 2021 Mar 18;51:102906. Epub 2021 Mar 18.

Department of Neurosciences, Division of Neurology, Unit of Neuroimmunology and Neuromuscular Diseases, Geneva University Hospitals, Geneva, Switzerland; Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland; Division of Laboratory Medicine, Department of Diagnostic, Geneva University Hospitals, Geneva, Switzerland. Electronic address:

Background: No studies assessing rabies vaccine (RV) tolerability in persons with multiple sclerosis (MS) have been conducted. Given the lack of safety data, RV is recommended essentially only for post-exposure prophylaxis, which is difficult to administer effectively in many rabies-endemic countries. We sought to determine whether RV administration as pre-exposure prophylaxis was associated with MS relapse. Read More

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Emergency Department-Based COVID-19 Vaccination: Where Do We Stand?

Acad Emerg Med 2021 Apr 7. Epub 2021 Apr 7.

Department of Emergency Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.

Cautious optimism suggests the COVID-19 pandemic in the United States (U.S.) has reached a turning point. Read More

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Tetanus in a rural low-income intensive care unit setting.

Brain Commun 2021 16;3(1):fcab013. Epub 2021 Feb 16.

Gulu University Faculty of Medicine, Gulu, Uganda.

Tetanus is a potentially severe but preventable infection. In resource-rich settings, vaccination programmes have reduced tetanus to a rare disease, though still carrying an overall mortality of some 13%. However, in low-income settings, tetanus remains common, and is a significant cause of mortality-though major World Health Organisation programmes are successfully targeting neonatal and maternal disease. Read More

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February 2021

COVID-19 vaccine impact on rates of SARS-CoV-2 cases and post vaccination strain sequences among healthcare workers at an urban academic medical center: a prospective cohort study.

medRxiv 2021 Mar 31. Epub 2021 Mar 31.

Background: COVID-19 vaccine trials and post-implementation data suggest vaccination decreases SARS-CoV-2 infections.

Objective: Estimate COVID-19 vaccination's impact on SARS-CoV-2 case rates and viral diversity among healthcare workers (HCW) during a high community prevalence period.

Design Setting Participants: A prospective cohort study from Boston Medical Center (BMC)'s HCW vaccination program, where staff received two doses of BNT162b2 or mRNA-1273. Read More

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Increasing hepatitis B vaccination coverage of healthcare workers - global lessons for South Africa.

Curr Opin Immunol 2021 Apr 2;71:6-12. Epub 2021 Apr 2.

South African Vaccination and Immunisation Centre, Sefako Makgatho Health Sciences University, Pretoria, South Africa; Division of Public Health Pharmacy and Management, Sefako Makgatho Health Sciences University, Pretoria, South Africa.

Healthcare workers (HCWs) are at high risk of contracting hepatitis B (HB), a severe blood-borne vaccine-preventable disease, caused by HB virus (HBV) infection. Low HB vaccine (HepB) coverage has resulted in suboptimal protection and high HBV infection rates in South African HCWs. Studies from Africa have identified cost; unavailability/lack of access to HepB; and lack of awareness/knowledge of HB and HepB, as barriers to HCW uptake. Read More

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COVID-19 infection in cancer patients: what has been the contribution of Associazione Italiana Oncologia Medica (AIOM) to oncological care since the beginning of the first pandemic wave?

ESMO Open 2021 Mar 19;6(2):100100. Epub 2021 Mar 19.

Medical Oncology Unit, Antonio Perrino Hospital, Brindisi, Italy. Electronic address:

High mortality rates in elderly patients or in those with underlying chronic illnesses and/or a compromised immune system is a peculiar feature of COVID-19 infection. The possible coexistence of a cancer and COVID-19 infection in the same individual prompted concerns regarding their synergistic effect on prognosis. In order to balance patients' needs with the risks related to the infection, the question oncologists have asked from the beginning of the first wave of the pandemic has been: 'how can we deal with COVID-19 infection in cancer patients?' In pursuing its mission, the Associazione Italiana Oncologia Medica (AIOM) has made every possible effort to support cancer patients, health care professionals and institutions in the decision-making processes the pandemic has engendered within this scenario. Read More

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Combatting Anti-Vaccination Misinformation: Improving Immunization Rates of Black/African American Children at UW Health.

WMJ 2021 Mar;120(S1):S31-S38

University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

Introduction: Vaccine hesitancy is a rising public health threat, thwarting progress to reduce vaccine-preventable diseases. While drivers of racial disparities in childhood immunization rates (CIR) have been described, none have explored these disparities at UW Health, and few have highlighted the role of anti-vaccination (anti-vaxx) campaigns in the Black/African American (BAA) community.

Objectives: This quality improvement study evaluates childhood immunization data for racial and ethnic disparities, identifies possible drivers, and proposes equitable solutions. Read More

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Vaccination Rates and Family Barriers Among Children with Inflammatory Bowel Disease.

Crohns Colitis 360 2020 Jul 7;2(3). Epub 2020 Jul 7.

Assistant Professor of Pediatrics, Pediatric Gastroenterology, Hepatology and Nutrition and Adolescent Comparative Effectiveness Research, Indiana University School of Medicine, 705 Riley Hospital Drive ROC 4210, Indianapolis, IN 46202, 317-944-3774.

Background: Many children with inflammatory bowel disease (IBD) are taking immunosuppressant medications that place them at risk for vaccine preventable diseases. Despite national guidelines, children with IBD have low vaccination rates. Adult data suggest that there is concern about the safety of vaccines. Read More

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Toward the Impact of Non-pharmaceutical Interventions and Vaccination on the COVID-19 Pandemic With Time-Dependent SEIR Model.

Front Artif Intell 2021 18;4:648579. Epub 2021 Mar 18.

Department of Mathematics and Statistics, Auburn University, Auburn, AL, United States.

The outbreak of COVID-19, caused by the SARS-CoV-2 coronavirus, has been declared a pandemic by the World Health Organization (WHO) in March, 2020 and rapidly spread to over 210 countries and territories around the world. By December 24, there are over 77 cumulative confirmed cases with more than 1.72 deaths worldwide. Read More

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Addressing Parental Vaccine Hesitancy and Other Barriers to Childhood/Adolescent Vaccination Uptake During the Coronavirus (COVID-19) Pandemic.

Front Immunol 2021 18;12:663074. Epub 2021 Mar 18.

Oak Ridge National Laboratory, Center for Biomedical Informatics, Department of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, United States.

Routine childhood immunizations are proven to be one of the most effective public health interventions at controlling numerous deadly diseases. Therefore, the CDC recommends routine immunizations for children and adolescent populations against vaccine-preventable diseases e.g. Read More

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Clinical repercussions in pertussis infants post-Tdpa vaccination of pregnant woman: An immunization success?

Vaccine 2021 Apr 1. Epub 2021 Apr 1.

Universidade de Pernambuco, Brazil. Electronic address:

Introduction: In 2014, there was an epidemic of pertussis in Brazil that caused the death of 129 infants. To control the disease amongst infants under 6 months of age, and especially those under 2 months, the Brazilian Ministry of Health introduced Tdap immunization for all pregnant women.

Methods: This study aimed to describe the morbidity and mortality variables of pertussis cases in 969 infants aged under 6 months, comparing the periods before and after the introduction of Tdap vaccine in pregnant women. Read More

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Oral and laryngeal HPV infection: Incidence, prevalence and risk factors, with special regard to concurrent infection in head, neck and genitals.

Vaccine 2021 Mar 31. Epub 2021 Mar 31.

Amsterdam UMC, University of Amsterdam, Department of Otorhinolaryngology, Head and Neck Surgery, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands. Electronic address:

This review focuses on the importance of oral and laryngeal HPV infection which is present in majority of sexually active individuals at least once in their lifetime. Despite testing, still little is known about prevalence rates, determinants and, especially, the concurrent HPV infection in head and neck, and genitals. The purpose of this review is to clarify some issues of oral HPV incidence, prevalence, and to demonstrate the difficulties in identification of asymptomatic oral HPV carriers. Read More

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Prioritising COVID-19 vaccination in changing social and epidemiological landscapes: a mathematical modelling study.

Lancet Infect Dis 2021 Mar 31. Epub 2021 Mar 31.

Department of Applied Mathematics, University of Waterloo, Waterloo, ON, Canada. Electronic address:

Background: During the COVID-19 pandemic, authorities must decide which groups to prioritise for vaccination in a shifting social-epidemiological landscape in which the success of large-scale non-pharmaceutical interventions requires broad social acceptance. We aimed to compare projected COVID-19 mortality under four different strategies for the prioritisation of SARS-CoV-2 vaccines.

Methods: We developed a coupled social-epidemiological model of SARS-CoV-2 transmission in which social and epidemiological dynamics interact with one another. Read More

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Dynamic prioritization of COVID-19 vaccines when social distancing is limited for essential workers.

Proc Natl Acad Sci U S A 2021 04;118(16)

Department of Environmental Science and Policy, University of California, Davis, CA 95616

COVID-19 vaccines have been authorized in multiple countries, and more are under rapid development. Careful design of a vaccine prioritization strategy across sociodemographic groups is a crucial public policy challenge given that 1) vaccine supply will be constrained for the first several months of the vaccination campaign, 2) there are stark differences in transmission and severity of impacts from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) across groups, and 3) SARS-CoV-2 differs markedly from previous pandemic viruses. We assess the optimal allocation of a limited vaccine supply in the United States across groups differentiated by age and essential worker status, which constrains opportunities for social distancing. Read More

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