533,553 results match your criteria urinary tract


Should Transanal Total Mesorectal Excision Be Implemented in Medium-Sized Colorectal Unit? Technical and Oncological Outcome.

Ann Coloproctol 2021 Jul 28. Epub 2021 Jul 28.

Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.

Purpose: This study was performed to evaluate the outcome of implementation of transanal total mesorectal excision (TaTME) for low rectal cancer in a regional hospital and in comparison to laparoscopic (Lap) TME.

Methods: Consecutive patients with low rectal cancer of which the lowest border of the tumour was located beween 1 and 5 cm from the puborectalis who underwent TME at North District Hospital between January 2013 and December 2019 were included. Clinical, operative, and pathologic outcomes were compared between Lap TME and TaTME. Read More

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The hot cross bun sign in corticobasal degeneration.

Neuropathology 2021 Jul 28. Epub 2021 Jul 28.

Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Nagakute, Japan.

The hot cross bun (HCB) sign encompasses a cross-shaped hyperintensity area in the pons on axial T2-weighted magnetic resonance imaging (MRI). The HCB sign is characteristic of multiple system atrophy (MSA) and has occasionally been observed in other neurological disorders. Here, we report an autopsied case of corticobasal degeneration (CBD) that showed the HCB sign. Read More

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Factors associated with the stone-free status after retrograde intrarenal surgery in children.

Int J Clin Pract 2021 Jul 28:e14667. Epub 2021 Jul 28.

Department of Urology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Introduction: Pediatric urolithiasis has a recurrent nature because it is frequently associated with metabolic or anatomical disorders or infectious conditions. The rising incidence of the disease with its recurrent nature emphasizes the need for minimally invasive therapeutic options. In this study, we aimed to evaluate efficacy and factors affecting the success of retrograde intrarenal surgery (RIRS) in children. Read More

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Predictive Accuracy of Prenatal Ultrasound Findings for Lower Urinary Tract Obstruction: A systematic review and Bayesian meta-analysis.

Prenat Diagn 2021 Jul 27. Epub 2021 Jul 27.

Division of Urology, The Hospital for Sick Children (SickKids), Toronto, Ontario, Canada.

Lower urinary tract obstruction (LUTO) is a rare but critical fetal diagnosis. Different ultrasound markers have been reported with varying sensitivity and specificity. The objective of this systematic review and meta-analysis was to identify the diagnostic accuracy of ultrasound markers for LUTO. Read More

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Lower urinary tract dysfunction in Parkinsonian syndromes.

Neurol Sci 2021 Jul 28. Epub 2021 Jul 28.

Department of Uro‑Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

Purpose Of Review: The aim of this review is to outline the clinical presentation, pathophysiology and evaluation of lower urinary tract (LUT) dysfunction in Parkinson's disease and other parkinsonian syndromes including multiple system atrophy, dementia with Lewy bodies, progressive supranuclear palsy and corticobasal degeneration.

Recent Findings: LUT dysfunction commonly occurs in neurological disorders, including patients with parkinsonian syndromes. The pattern of LUT dysfunction and its severity are variable, depending upon the site of lesion within the neural pathways. Read More

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A mechanism linking perinatal 2,3,7,8 tetrachlorodibenzo-p-dioxin exposure to lower urinary tract dysfunction in adulthood.

Dis Model Mech 2021 Jul 27;14(7). Epub 2021 Jul 27.

Molecular and Environmental Toxicology Center, University of Wisconsin-Madison,Madison, WI 53705, USA.

Benign prostatic hyperplasia/lower urinary tract dysfunction (LUTD) affects nearly all men. Symptoms typically present in the fifth or sixth decade and progressively worsen over the remainder of life. Here, we identify a surprising origin of this disease that traces back to the intrauterine environment of the developing male, challenging paradigms about when this disease process begins. Read More

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Telocytes, c-Kit positive cells, Smooth muscles, and collagen in the ureter of pediatric patients with congenital primary obstructive megaureter: elucidation of etiopathology.

Ultrastruct Pathol 2021 Jul 27:1-9. Epub 2021 Jul 27.

Department of Urology, Theodor Bilharz Research Institute, Cairo, Egypt.

Congenital primary obstructive megaureter (POM) is an uncommon pediatric anomaly that is due to obstructive distal ureter leading to the loss of peristalsis with consequent ureterohydronephrosis causing loss of kidney function. The objectives are to elucidate the etiology of POM by demonstrating the presence of interstitial cells of Cajal (ICC), telocytes, smooth muscles, and collage in the obstructive and dilated ureteral segments. The study was carried out on 15 surgical specimens of congenital POM in pediatric patients, age range was 4 to 24 months, they were operated upon by excision of the obstructed segment, tailoring the dilated ureter, and anastomosing it to the bladder. Read More

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Amyloidosis of the urinary bladder: a systematic review and a proposed management algorithm.

Urology 2021 Jul 24. Epub 2021 Jul 24.

Urology Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece; Urology Department, The Pennine Acute Hospitals NHS Trust, Manchester, UK.

Objective: To propose an algorithm for the management of bladder amyloidosis based on a systematic review of the literature, given that the bladder is the second most commonly affected organ of the urinary tract in the course of systemic or localized amyloidosis.

Methods: We searched PubMed, Cochrane Library and Scopus databases utilizing PRISMA methodology from inception to November 30, 2020 (PROSPERO: CRD42020207855).

Results: We included 76 studies with 184 patients (9 case series and 67 case reports). Read More

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Perioperative impact of body mass index on upper urinary tract and renal robot-assisted surgery: a single high-volume centre experience.

J Robot Surg 2021 Jul 27. Epub 2021 Jul 27.

Specialist Centre for Kidney Cancer, Royal Free London NHS Foundation Trust, Hampstead, London, UK.

To assess the impact of body mass index (BMI) on peri-operative outcomes of kidney and upper tract robot-assisted surgery. Medical audit of patients who underwent robot-assisted kidney and upper tract cancer surgery at a single institution between 2017 and 2019, categorized on BMI into obese patients with a BMI ≥ 30 kg/m and a control group with BMI < 25 kg/m. Patient and tumour characteristics, surgery time, intraoperative blood loss, intraoperative adverse events (AE) according to the European Association of Urology Intraoperative Adverse Incidents Classification (EAUiaiC), conversion- to-open/radical rate as well as 30-day postoperative AE according to Clavien-Dindo (CD) and length of inpatient stay were analyzed. Read More

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Shorter Courses of Antibiotics for Urinary Tract Infection in Men.

JAMA 2021 07;326(4):309-310

Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore.

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Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial.

JAMA 2021 07;326(4):324-331

Minneapolis Veterans Affairs Health Care System, Minneapolis, Minnesota.

Importance: Determination of optimal treatment durations for common infectious diseases is an important strategy to preserve antibiotic effectiveness.

Objective: To determine whether 7 days of treatment is noninferior to 14 days when using ciprofloxacin or trimethoprim/sulfamethoxazole to treat urinary tract infection (UTI) in afebrile men.

Design, Setting, And Participants: Randomized, double-blind, placebo-controlled noninferiority trial of afebrile men with presumed symptomatic UTI treated with ciprofloxacin or trimethoprim/sulfamethoxazole at 2 US Veterans Affairs medical centers (enrollment, April 2014 through December 2019; final follow-up, January 28, 2020). Read More

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Thulium laser vapo-enucleation treatment for prostates >100 cc following urinary retention.

Urologia 2021 Jul 27:3915603211016325. Epub 2021 Jul 27.

University Hospitals of Leicester NHS Trust, Leicester, UK.

Introduction: Practical advantages of Thulium in the endoscopic treatment of BPH include its technical versatility, precision and safety, offering reduced need for haemostasis and risk of injury. Evidence has shown Holmium laser to be effective in the treatment of chronic retention, however no studies address the use of Thulium laser for larger prostates after urinary retention.

Objectives: We have selected this group in our retrospective analysis on the efficacy of Thulium laser vapo-enucleation for men with both urinary retention and large prostate volumes greater than 100 cc. Read More

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Dysbiosis of the Urinary Bladder Microbiome in Cats with Chronic Kidney Disease.

mSystems 2021 Jul 27:e0051021. Epub 2021 Jul 27.

Centre for Companion Animal Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Konggrid.35030.35, Hong Kong SAR.

Although feline urinary tract diseases cause high morbidity and mortality rates, and subclinical bacteriuria is not uncommon, the feline urinary microbiome has not been characterized. We conducted a case-control study to identify the feline urinary bladder microbiome and assess its association with chronic kidney disease (CKD), feline idiopathic cystitis (FIC), and positive urine cultures (PUCs). Of 108 feline urine samples subjected to 16S rRNA gene sequencing, 48 (44. Read More

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Effectiveness of standard urotherapy (basic bladder advice) and combination therapies in managing bladder dysfunction in children with treated behavioral disorders: Results of a prospective cohort (DABBED) study.

Low Urin Tract Symptoms 2021 Jul 27. Epub 2021 Jul 27.

John Hunter Children's Hospital, New Lambton Heights, New South Wales, Australia.

Aims: We evaluated the efficacy of standard urotherapy and combination therapies in treatment of bladder dysfunction in children with treated behavioral disorders.

Methods: Prospective study of children (6-16 years) with bladder dysfunction and behavioral disorders was conducted between March 2018-2020. Eligible children were initially offered standard urotherapy and those with no response at 3 months were offered combination therapies. Read More

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Urinary tract infection by atypical uropathogens in dogs.

Vet Ital 2021 May 11;57(1):89-92. Epub 2021 May 11.

Department of Veterinary Medicine, University of Milan, Lodi, Italy.

Bacterial urinary tract infection (UTI) is a common condition affecting dogs. Urine culture and antimicrobial susceptibility test, associated with the identification of underlying cause, are of primary importance in order to select a correct treatment, especially in presence of comorbidities. Two cases of immunecompromised dogs affected by urinary tract infection (UTI) have been described: the first, probably immunosuppressed due to old age, was in poor body condition, with severe odontolithiasis and periodontitis; the second was affected by chronic kidney disease in advanced stage. Read More

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Envisioning treating genetically-defined urinary tract malformations with viral vector-mediated gene therapy.

J Pediatr Urol 2021 Jul 7. Epub 2021 Jul 7.

Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, UK. Electronic address:

Human urinary tract malformations can cause dysfunctional voiding, urosepsis and kidney failure. Other affected individuals, with severe phenotypes on fetal ultrasound screening, undergo elective termination. Currently, there exist no specific treatments that target the primary biological disease mechanisms that generate these urinary tract malformations. Read More

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Adverse events associated with mirabegron 50mg versus placebo: A systematic review and meta-analysis.

Authors:
J Hou F Xu H Du N Li

Prog Urol 2021 Jul 23. Epub 2021 Jul 23.

Department of Urology, Fourth Affiliated Hospital, China Medical University, 4 Chong Shan East Road, Shenyang, Liaoning, China. Electronic address:

Purpose: The safety of mirabegron 50mg monotherapy was comprehensively assessed versus placebo for overactive bladder.

Methods: A systematic literature search was conducted up to June, 2020 using PUBMED, EMBASE and Cochrane Library. Randomized controlled trials evaluating safety of mirabegron in overactive bladder were collected, and safety was assessed according to 15 adverse events. Read More

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Renal agenesis-related genes are associated with Herlyn-Werner-Wunderlich syndrome.

Fertil Steril 2021 Jul 23. Epub 2021 Jul 23.

Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Chaoyang, Beijing, People's Republic of China; Beijing Maternal and Child Health Care Hospital, Chaoyang, Beijing, People's Republic of China. Electronic address:

Objective: To explore the genetic causes of Herlyn-Werner-Wunderlich syndrome (HWWS) using whole-exome sequencing.

Design: Retrospective genetic study.

Setting: Academic medical center. Read More

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Asymptomatic But Altered? When Urinalysis Holds the Key.

Sr Care Pharm 2021 Aug;36(8):381-386

Altered mental status (AMS) is a common symptom in geriatric patients, especially in the long-term care setting. Traditionally, AMS has been associated with urinary tract infections (UTIs) in older people. However, data correlating UTIs with AMS are lacking. Read More

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Lower urinary tract signs and symptoms in patients with COVID-19.

BMC Infect Dis 2021 Jul 26;21(1):706. Epub 2021 Jul 26.

Uniklinik RWTH Aachen, Pauwelsstrasse 30, 52074, Aachen, Germany.

Background: The type of pneumonia that is caused by the new coronavirus (SARS-CoV-2) has spread across the world in a pandemic. It is not clear if COVID-19 patients have any lower urinary tract signs or symptoms.

Methods: The effect of COVID-19 on lower urinary tract function was studied in a prospective multi-centre, observational study including 238 patients who were admitted with symptoms caused by COVID-19 to the university hospital of Aachen in Germany and Tabriz in Iran. Read More

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Hip hemiarthroplasty for the treatment of femoral neck fractures in dialysis patients.

Hip Int 2021 Jul 26:11207000211028151. Epub 2021 Jul 26.

Department of Orthopaedic Surgery, The George Washington University, Washington, DC, USA.

Objectives: This study sought to delineate the postoperative outcomes in dialysis patients undergoing hip hemiarthroplasty (HHA) for the treatment of femoral neck fractures (FNF) in order to better optimise pre- and postoperative management and minimise short-term morbidity and mortality rates.

Methods: 16,955 patients who had undergone HHA for femoral neck fractures from 2005 to 2018 were isolated from a multi-institutional surgical registry, of which 343 (2.0%) were on dialysis and 16,612 (98. Read More

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Clinical outcomes and prognostic factors associated with nonsteroidal anti-inflammatory drug overdose in dogs presented to an emergency room.

J Vet Emerg Crit Care (San Antonio) 2021 Jul 23. Epub 2021 Jul 23.

Department of Clinical Sciences and Advanced Medicine, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA.

Objective: To describe case presentations, clinical signs, and outcomes following nonsteroidal anti-inflammatory drug (NSAID) overdose in a clinical population of dogs and to identify factors associated with various outcomes including death or euthanasia, acute kidney injury, and suspected gastrointestinal ulceration (GIU).

Design: Retrospective study.

Setting: University teaching hospital. Read More

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Phenotypic and Genotypic Characteristics of Uropathogenic Isolates from Kenya.

Microb Drug Resist 2021 Jul 23. Epub 2021 Jul 23.

Department of Emerging Infectious Diseases, United States Army Medical Research Directorate-Africa, Kenya/Kenya Medical Research Institute, Nairobi, Kenya.

Uropathogenic (UPECs) are a significant cause of urinary tract infections (UTIs). In Kenya, UTIs are typically treated with β-lactam antibiotics without antibiotic susceptibility testing, which could accelerate antibiotic resistance among UPEC strains. This study determined the occurrence of UPEC producing extended-spectrum β-lactamases (ESBLs), the genes conferring resistance to β-lactams, and the phylogenetic groups associated with ESBLs in Kenyan UPECs. Read More

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Frequency, Distribution, and Antimicrobial Resistance of Coagulase-Negative Staphylococci Isolated from Clinical Samples in Dogs and Cats.

Microb Drug Resist 2021 Jul 23. Epub 2021 Jul 23.

Department of Pre-clinic and Applied Animal Science, Faculty of Veterinary Science, Mahidol University, Nakhon Pathom, Thailand.

This study aimed to investigate the frequency, distribution, and antimicrobial resistance of coagulase-negative staphylococci (CoNS) obtained from clinical samples from dogs and cats and to classify any methicillin-resistant CoNS (MRCoNS). The samples were collected in 2017-2018, and species identification and antimicrobial susceptibility testing were routinely performed using the Vitek2 system. Among 1,056 staphylococci, 185 CoNS (17. Read More

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Purple urine bag syndrome in a patient on haemodialysis.

Med J Aust 2021 Jul 22. Epub 2021 Jul 22.

Nepean Hospital, Sydney, NSW.

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Corrigendum to "Update of the EAU/ESPU guidelines on urinary tract infections in children" [J Pediatr Urol 17 (2021) 200-207].

J Pediatr Urol 2021 Jul 19. Epub 2021 Jul 19.

Center for Pediatric, Adolescent and Reconstructive Urology, Medical Faculty Mannheim, University of Medical Center Mannheim, Heidelberg University, Mannheim, Germany.

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Letter to the Editor re 'Update of the EAU/ESPU guidelines on urinary tract infections in children'.

J Pediatr Urol 2021 Jul 6. Epub 2021 Jul 6.

University Children's Hospital, Uppsala, Sweden. Electronic address:

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Effect of shape and anthocyanin capping on antibacterial activity of CuI particles.

Environ Res 2021 Jul 23;200:111759. Epub 2021 Jul 23.

Department of Integrative Biology, School of Biosciences and Technology, Vellore Institute of Technology, Vellore, India.

The recent upsurge of antibiotic-resistant infections has posed to be a serious health concern worldwide. In the present paper, the effect of shape & capping agent on the antibacterial activity (on Skin and Urinary Tract Infection (UTI) causing bacteria) of copper iodide (CuI) particles was probed. CuI synthesized without a capping agent was leaf-like, and that with one was prismatic in shape. Read More

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