185,179 results match your criteria urea molecules

Differences in kinetic metabolomics in Eisenia fetida under single and dual exposure of imidacloprid and dinotefuran at environmentally relevant concentrations.

J Hazard Mater 2021 May 8;417:126001. Epub 2021 May 8.

Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China. Electronic address:

Metabolomic responses of earthworms to neonicotinoids are important for understanding their molecular-level toxicity and assessing their ecological risks, but little is known until now. We investigated impact of imidacloprid (IMI, 52.6 ng/g) and dinotefuran (DIN, 52. Read More

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Nitrate leaching and NH volatilization during soil reclamation in the Yellow River Delta, China.

Environ Pollut 2021 May 10;286:117330. Epub 2021 May 10.

Yellow River Delta Ecological Research Station of Coastal Wetlands, Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, 264003, China.

The agricultural ecological system is an important part of the Yellow River Delta (YRD); however, soil reclamation may trigger environmental concerns about nitrate leaching and NH volatilization in this area. To assess nitrogen losses during soil reclamation, a two-year field experiment was conducted with plastic film mulch, which is an effective way to alleviate water-salt stress. The Hydrus-2D software package was used to calculate nitrogen transport, transformation and losses. Read More

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The arachidonic acid metabolite 11,12-epoxyeicosatrienoic acid alleviates pulmonary fibrosis.

Exp Mol Med 2021 May 14. Epub 2021 May 14.

Department of Pulmonary and Critical Care Medicine, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid that are rapidly metabolized into diols by soluble epoxide hydrolase (sEH). sEH inhibition has been shown to increase the biological activity of EETs, which are known to have anti-inflammatory properties. However, the role of EETs in pulmonary fibrosis remains unexplored. Read More

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Modulatory effects of carvacrol against cadmium-induced hepatotoxicity and nephrotoxicity by molecular targeting regulation.

Life Sci 2021 May 11;277:119610. Epub 2021 May 11.

Erzurum Veterinary Control Institute, 25070 Erzurum, Turkey.

Aim: Cadmium (Cd) is a toxic heavy metal that causes severe toxic effects on different tissues including liver and kidney. Therefore the research for alternatives to reduce the damage caused by Cd has substantial importance. This study was performed to examine the possible modulatory effects of carvacrol (CRV) against Cd-induced hepatorenal toxicities and the possible mechanisms underlying these effects. Read More

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Biosensing approaches to detect potential milk contaminants: a comprehensive review.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2021 May 14:1-24. Epub 2021 May 14.

Chemistry Department, School of Sciences & Engineering, The American University in Cairo, New Cairo, Egypt.

Accidentally present contaminants or intentionally added adulterants in milk lead potentially to delivering not only unhealthy but seriously hazardous products. Thorough, fast and sensitive analytical tools are essential for monitoring of milk quality, and for screening of any objectionable contaminants. Biosensors represent an innovative, time-efficient and on-site solution to assess milk quality in addition to their specificity towards target analytes alongside high accuracy within such complex matrices. Read More

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Inhibition of the p38 MAPK pathway attenuates renal injury in pregnant rats with acute necrotizing pancreatitis.

Immunol Res 2021 May 14. Epub 2021 May 14.

Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, People's Republic of China.

The p38 mitogen-activated protein kinase (MAPK) pathway is an important intracellular signalling pathway that leads to increased expression of pro-inflammatory mediators. Our previous studies have shown that the p38 MAPK pathway was changed in the acute renal injury (ARI) in acute pancreatitis in late pregnancy (APIP), whereas the role of p38 MAPK in APIP-induced ARI has been poorly understood. The present study was undertaken to investigate the participation of the p38 MAPK signalling pathway and the protective effect of SB203580, an inhibitor of p38 MAPK in ARI in APIP. Read More

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Enhanced protein and amino acids of corn-ethanol co-product by Mucor indicus and Rhizopus oryzae.

Bioprocess Biosyst Eng 2021 May 14. Epub 2021 May 14.

Department of Bioproducts and Biosystems Engineering, University of Minnesota, 1390 Eckles Ave, Saint Paul, MN, 55108-6005, USA.

Upcycle of co-products from corn-ethanol plant into protein-rich animal feed with balanced key amino acids via solid-state fermentation is a promising approach to economically support both biofuel and animal feed industries. However, there are multiple types of solid-state fermentation microorganisms and growth conditions that have not been tested. In this study, Mucor indicus and Rhizopus oryzae were used to ferment corn-based wet distiller's grains with solubles (WDGS). Read More

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Synthesis, characterization and molecular docking studies of new indol(1-3-yl)pyrimidine derivatives: Insights into their role in DNA interaction.

Nucleosides Nucleotides Nucleic Acids 2021 May 14:1-16. Epub 2021 May 14.

Department of Studies in Chemistry, Bangalore University, Bangalore, Karnataka, India.

This study reports the synthesis of new indol(1-3-yl) pyrimidine derivatives using various substituted indole-3-carbaldehydes, urea and malononitrile in the presence of ammonium chloride. The resulting compounds were characterized using analytical and spectroscopic methods. The molecular docking study exhibits that among the synthesized compounds, have great binding ability toward B-DNA. Read More

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Mitigation of yield-scaled greenhouse gas emissions from irrigated rice through Azolla, Blue-green algae, and plant growth-promoting bacteria.

Environ Sci Pollut Res Int 2021 May 13. Epub 2021 May 13.

Division of Microbiology, ICAR-Indian Agricultural Research Institute, New Delhi, 110012, India.

Irrigated transplanted flooded rice is a major source of methane (CH) emission. We carried out experiments for 2 years in irrigated flooded rice to study if interventions like methane-utilizing bacteria, Blue-green algae (BGA), and Azolla could mitigate the emission of CH and nitrous oxide (NO) and lower the yield-scaled global warming potential (GWP). The experiment included nine treatments: T (120 kg N ha urea), T (90 kg N ha urea + 30 kg N ha fresh Azolla), T (90 kg N ha urea + 30 kg N ha Blue-green algae (BGA), T (60 kg N ha urea + 30 kg N ha BGA + 30 kg N ha Azolla, T (120 kg N ha urea + Hyphomicrobium facile MaAL69), T (120 kg N ha by urea + Burkholderia vietnamiensis AAAr40), T (120 kg N ha by urea + Methylobacteruim oryzae MNL7), T (120 kg N ha urea + combination of Burkholderia AAAr40, Hyphomicrobium facile MaAL69, Methylobacteruim oryzae MNL7), and T (no N fertilizer). Read More

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Effects of alfalfa and alfalfa-grass mixtures with nitrogen fertilization on dry matter yield and forage nutritive value.

J Anim Sci Technol 2021 Mar 31;63(2):305-318. Epub 2021 Mar 31.

Department of Agronomy, Kansas State University, Manhattan, KS 66506, USA.

Alfalfa ( L.) is an important forage legume grown in Kansas, USA and its productivity with cool-season grasses however is unknown. The objective of this study was to determine the dry matter yield (DMY) and forage nutritive value of alfalfa-grass mixtures compared to those of alfalfa and grasses grown in monoculture with and without nitrogen fertilization. Read More

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Growth performance and blood profiles of Hanwoo steers at fattening stage fed Korean rice wine residue.

J Anim Sci Technol 2020 Nov 30;62(6):812-823. Epub 2020 Nov 30.

Ruminant Nutrition and Anaerobe Laboratory, Department of Animal Science and Technology, Sunchon National University, Suncheon 57922, Korea.

The aim of this study was to investigate the effects of Korean rice wine residue (RWR) on the growth performance and blood profiles of Hanwoo steers in the fattening stage. and experiments were conducted to analyze rumen fermentation characteristics and total tract digestibility, respectively. Three cannulated Hanwoo steers (mean body weight: 448 ± 30 kg) were used in both analyses. Read More

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November 2020

False-positive colloidal gold-based immunochromatographic strip assay reactions for antibodies to SARS-CoV-2 in patients with autoimmune diseases.

Ann Transl Med 2021 Apr;9(7):534

The Department of Laboratory Medicine, Peking University Third Hospital, Beijing, China.

Background: The outbreak of the novel 2019 coronavirus disease (COVID-19) was declared a global pandemic by the World Health Organization (WHO) on March 11, 2020. The diagnosis of COVID-19 is frequently based on a positive serological test. We noted the occurrence of false-positive results for COVID-19 in the colloidal gold-based immunochromatographic strip (ICS) assay in sera from patients with autoimmune diseases (ADs). Read More

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Boldenone Undecylenate-Mediated Hepatorenal Impairment by Oxidative Damage and Dysregulation of Heat Shock Protein 90 and Androgen Receptors Expressions: Vitamin C Preventive Role.

Front Pharmacol 2021 27;12:651497. Epub 2021 Apr 27.

Department of Biochemistry, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.

Boldenone Undecylenate (BLD) is a synthetic derivative of testosterone and a widely used anabolic androgenic steroid. The health risk of BLD use as a pharmaceutical or dietary supplement is still underestimated and under-reported. Vitamin C (VC) has been recognized as an antioxidant with prominent hepatorenal protective effects. Read More

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Bone loss in hepatitis B virus-infected patients can be associated with greater osteoclastic activity independently of the retroviral use.

Sci Rep 2021 May 13;11(1):10162. Epub 2021 May 13.

Department of Clinical Medicine, Ribeirão Preto Medical School, University of São Paulo - FMRP/USP, São Paulo, Brazil.

Nucleoside/nucleotide analogs such as tenofovir, have been used as long-term therapy for the treatment of hepatitis B and side effects such as the reduction in bone mineral density have been associated with their use. To determine the relationships between bone, hormonal, biochemical, and mineral parameters in patients with hepatitis B treated with nucleoside/nucleotide antiviral. A cross-sectional study was conducted with 81 adult patients with chronic hepatitis B infection. Read More

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Blood parameters of young calves at abattoirs are related to distance transported and farm of origin.

J Dairy Sci 2021 May 10. Epub 2021 May 10.

Animal Welfare Science Centre, The University of Melbourne, Parkville, Victoria 3052, Australia; Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Werribee, Victoria 3030, Australia.

Nonreplacement dairy calves, or bobby calves, are fasted and transported to abattoirs from as young as 5 d of age in Australia. The aims of this cross-sectional observational study were (1) to assess the welfare status, as measured by blood parameters, of bobby calves in the commercial supply chain after transport and lairage, and (2) to assess whether distance and duration of transport are risk factors for poor bobby calf welfare, as measured by blood parameters. We hypothesized that bobby calves transported greater distances would be more likely to show evidence of compromised welfare, as measured by blood indicators of hydration, energy status, and muscle fatigue or damage. Read More

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Use of the Comprehensive Climate Index to estimate heat stress response of grazing dairy cows in a temperate climate region.

J Dairy Res 2021 May 14:1-8. Epub 2021 May 14.

Facultad de Ciencias Agrarias y Alimentarias, Instituto de Producción Animal, Universidad Austral de Chile, Valdivia, Chile.

The aim of the study was to assess the effect of the summer thermal environment on physiological responses, behaviour, milk production and its composition on grazing dairy cows in a temperate climate region, according to the stage of lactation. Twenty-nine Holstein Friesian multiparous cows were randomly selected and divided into two groups, according to the days in milk, as mid-lactation (99 to 170 d in milk, n = 15) and late lactation (225 to 311 d in milk, n = 14). The comprehensive climate index (CCI) was used to classify the hour of each day as thermoneutral or heat stress, considering a threshold value of CCI of 20°C. Read More

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Simultaneous remediation and fertility improvement of heavy metals contaminated soil by a novel composite hydrogel synthesized from food waste.

Chemosphere 2021 Jul 20;275:129984. Epub 2021 Feb 20.

The State Key Laboratory of Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Tongji University, 1239 Siping Road, Shanghai, 200092, China; Shanghai Institute of Pollution Control and Ecological Security, 1515 North Zhongshan Rd. (No. 2), Shanghai, 200092, PR China. Electronic address:

Soil contamination by heavy metals constitutes a serious global environmental problem, and numerous remediation technologies have been developed. In this study, a novel soil remediation agent, namely composite hydrogel (leftover rice-g-poly(acrylic acid)/montmorillonite/Urea, LR-g-PAA/MMT/urea), was prepared based on free radical polymerization cross-linking technology. Experimental results indicated that the LR-g-PAA/MMT/urea dosage increased from 0% to 10%, the oxidizable state proportions of Cd, Cu, Pb and Zn in contaminated soil increased from 8. Read More

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Synergistic effect of glutaric acid and ammonia/amine/amide on their hydrates in the clustering: A theoretical study.

Chemosphere 2021 Jul 22;275:130063. Epub 2021 Feb 22.

Institute of Functional Material Chemistry, National & Local United Engineering Lab for Power Battery, Faculty of Chemistry, Northeast Normal University, Changchun, 130024, People's Republic of China. Electronic address:

The formation of molecular clusters makes influence on the atmosphere. The clusters of glutaric acid (GA) and common ammonia (A), amine (methylamine MA, dimethylamine DMA) and representative amide (urea U) along with water molecule were systematically studied theoretically. GA-A-nW (n = 1, 2), GA-MA-nW (n = 1, 2), GA-DMA-1W and GA-U-nW (n = 1-6) are predicted to be feasible thermodynamically with the hydrogen bonds as interaction force. Read More

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Thiosulfate enhanced degradation of organic pollutants in aqueous solution with g-CN under visible light irradiation.

Chemosphere 2021 Jul 26;275:130119. Epub 2021 Feb 26.

School of Chemistry and Chemical Engineering, Wuhan Textile University, Wuhan, 430200, PR China; Engineering Research Center for Clean Production of Textile Dyeing and Printing, Ministry of Education, Wuhan, 430200, PR China. Electronic address:

Developing new strategies to design more practicable and efficient g-CN based photocatalysts is important to solve the environmental issues. Thiosulfate (STS) is a common residual product found in wastewater and removal of STS remains a matter of great environmental concern. In this work, however, STS is activated by g-CN under visible light irradiation, resulting in a fast degradation of Rhodamine B (RhB) and other pollutants. Read More

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Agomelatine prevents gentamicin nephrotoxicity by attenuating oxidative stress and TLR-4 signaling, and upregulating PPARγ and SIRT1.

Life Sci 2021 May 10:119600. Epub 2021 May 10.

Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Egypt.

Kidney injury is a relatively common complication of the use of aminoglycosides. Inflammation and oxidative stress play a key role in gentamicin (GM) nephrotoxicity. We investigated the protective effect of the melatonergic agonist agomelatine (AGM) on GM nephrotoxicity, emphasizing the involvement of TLR-4 signaling, SIRT1 and PPARγ. Read More

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Beclin-1, an autophagy-related protein, is associated with the disease severity of COVID-19.

Life Sci 2021 May 10:119596. Epub 2021 May 10.

Hatay Mustafa Kemal University, Faculty of Medicine, Department of Infection Disease and Clinical Microbiology, Hatay, Turkey.

Aims: Coronavirus disease 2019 (COVID-19), which is a highly contagious disease, is an ongoing outbreak worldwide with high morbidity and mortality. The approaches targeting the autophagy processes might have promising diagnostic and therapeutic values against Coronavirus infection. Here, we aimed to investigate the relationship of Beclin-1 (BECN1), an autophagy-related protein, with blood parameters and the clinical severity in patients with COVID-19. Read More

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Amelioration of lithiatic injury to renal tissue by candesartan and sodium thiosulfate in a rat model of nephrolithiasis.

PLoS One 2021 13;16(5):e0251408. Epub 2021 May 13.

Department of Biochemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt.

Aim: Nephrolithiasis is a chronic metabolic condition affecting 10% of population worldwide. The present study aimed to investigate the possible protective role of candesartan (CAND) and sodium thiosulfate (STS) in ameliorating ethylene glycol (EG) induced nephrolithiasis.

Methods: One hundred male Wistar rats were divided into five groups: Normal control group, nephrolithiasis (EG) group (1% EG in drinking water), Cystone (CYS) group (EG + 750 mg/kg CYS, orally, once daily), STS group (EG + 0. Read More

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Effect of borates on the synthesis of nanoscale hexagonal boron nitride by a solid-state method.

Microsc Res Tech 2021 May 13. Epub 2021 May 13.

Department of Mechanical Engineering, Bolu Abant Izzet Baysal University, Bolu, Turkey.

This study delves deeply into the effect of different borates (lithium tetraborate, sodium tetraborate, calcium metaborate, ammonium pentaborate) on the production and fundamental characteristic features of nanoscale hexagonal boron nitride (hBN) structure with the assistant of standard characteristic measurement methods, namely, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning and transmission electron microscopy (SEM and TEM). The hBN samples are synthesized by reaction of powder urea, boron oxide, and different kinds of borates via the modified O'Connor method (performed at a relatively lower main heat treatment temperature of 1,100°C). All the results obtained show that the usage of borates affects positively the formation of nanoscale hBN structure. Read More

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Anatomy of a deep eutectic solvent: structural properties of choline chloride : sesamol 1 : 3 compared to reline.

Phys Chem Chem Phys 2021 May 13. Epub 2021 May 13.

Department of Chemistry, University "La Sapienza", P.le A. Moro 5, 00185, Rome, Italy.

The structural properties of the deep eutectic solvent (DES) formed by choline chloride (ChCl) and sesamol in 1 : 3 ratio have been investigated and compared to those of reline (ChCl : urea 1 : 2). An integrated approach combining small and wide angle X-ray scattering with molecular dynamics simulations has been employed and the simulation protocol has been validated against the experimental data. In the ChCl : sesamol DES, strong hydrogen bonds (HBs) are formed between the chloride anion and the hydroxyl groups of the choline and of sesamol molecules. Read More

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Age- and sex-specific reference intervals for blood urea nitrogen in Chinese general population.

Sci Rep 2021 May 12;11(1):10058. Epub 2021 May 12.

Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China.

Blood urea nitrogen (BUN) is a nitrogenous end product of protein metabolism. This study aims to explore the age- and sex-specific distribution of BUN among healthy Chinese adults. A total of 24,006 BUN values from healthy adults (14,148 males and 9858 females) were included in the cross-sectional study. Read More

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Nitrogen form, concentration, and micronutrient availability affect microcystin production in cyanobacterial blooms.

Harmful Algae 2021 Mar 27;103:102002. Epub 2021 Feb 27.

Center for Reservoir and Aquatic Systems Research, Baylor University, Waco, TX 76798, United States; Department of Biology, Baylor University, Waco, TX 76798, United States.

Harmful algal blooms (HABs) are increasing in magnitude, frequency, and duration caused by anthropogenic factors such as eutrophication and altered climatic regimes. While the concentrations and ratios of nitrogen (N) and phosphorus are correlated with bloom biomass and cyanotoxin production, there is less known about how N forms and micronutrients (MN) interact to regulate HABs and cyanotoxin production. Here, we used two separate approaches to examine how N and MN supply affects cyanobacteria biomass and cyanotoxin production. Read More

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Transcriptome responses of the dinoflagellate Karenia mikimotoi driven by nitrogen deficiency.

Harmful Algae 2021 Mar 27;103:101977. Epub 2021 Jan 27.

Fujian Engineering Research Center for Comprehensive Utilization of Marine Products Waste, Fuzhou University, Fujian 350116, China; Fujian Key Laboratory of Marine Enzyme Engineering, Fuzhou University, Fujian 350116, China. Electronic address:

The availability of ambient N nutrient is often correlated with the occurrences of harmful algal bloom formed by certain dinoflagellates, making it important to understand how these species might be responding to such conditions. Here, transcriptome sequencing of Karenia mikimotoi was conducted to understand the underlying molecular mechanisms by which this dinoflagellate copes with nitrogen (N) deficiency. Transcriptomic analysis revealed 8802 unigenes (3. Read More

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Metabolic differences among newborns born to mothers with a history of leukemia or lymphoma.

J Matern Fetal Neonatal Med 2021 May 12:1-8. Epub 2021 May 12.

Department of Epidemiology, University of Iowa, Iowa City, IA, USA.

Background: Leukemia and lymphoma are cancers affecting children, adolescents, and young adults and may affect reproductive outcomes and maternal metabolism. We evaluated for metabolic changes in newborns of mothers with a history of these cancers.

Methods: A cross-sectional study was conducted on California births from 2007 to 2011 with linked maternal hospital discharge records, birth certificate, and newborn screening metabolites. Read More

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Mobility of insecticide residues and main intermediates in a clay-loam soil, and impact of leachate components on their photocatalytic degradation.

Chemosphere 2021 Jul 15;274:129965. Epub 2021 Feb 15.

Department of Agricultural Chemistry, Geology and Pedology, Faculty of Chemistry, University of Murcia, Campus Universitario de Espinardo, 30100, Murcia, Spain.

This work assesses the behavior (adsorption, degradation and leaching) of four insecticides (chlorantraniliprole, thiametoxam, imidacloprid and pirimicarb) and their main reaction intermediates in a clay-loam textured soil (1.6% OM). Following the batch equilibrium method, the K (as log values) ranged from 1. Read More

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