175,602 results match your criteria university illinois


Comparison of Short-term Results after Laparoscopic Complete Mesocolic Excision and Standard Colectomy for Right-Sided Colon Cancer: Analysis of a Western Center Cohort.

Ann Coloproctol 2021 Apr 22. Epub 2021 Apr 22.

Division of General and Hepatobiliary Surgery, Department of Surgical Sciences, Dentistry, Gynecology, and Pediatrics, University of Verona Hospital Trust, University of Verona, Italy.

Purpose: Laparoscopic complete mesocolic excision (CME) right colectomy is a technically demanding procedure infrequently employed in Western centers. This retrospective cohort study aims to analyze the safety of laparoscopic CME colectomy compared to standard colectomy for right-sided colon cancer in a Western series.

Methods: Prospectively collected data from 60 patients who underwent laparoscopic CME right colectomy were compared to the ones of 55 patients who underwent laparoscopic standard right colectomy. Read More

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A telehealth initiative to decrease no-show rates in a pediatric asthma mobile clinic.

J Pediatr Nurs 2021 Apr 19;59:143-150. Epub 2021 Apr 19.

University of Illinois at Chicago, 845 S Damen Ave, Chicago, IL 60612, United States of America. Electronic address:

Background/problem: Failed patient care appointments (no-shows) can lead to negative patient health outcomes and increased healthcare costs. There is evidence that telehealth is a safe, effective, and a cost-efficient option for those unable to attend in-person visits. No-show rates in pediatrics are unique due to reliance on caregivers to attend appointments. Read More

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Budesonide Oral Suspension Improves Outcomes in Patients With Eosinophilic Esophagitis: Results from a Phase 3 Trial.

Clin Gastroenterol Hepatol 2021 Apr 19. Epub 2021 Apr 19.

Center for Esophageal Diseases and Swallowing, Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Background & Aims: Eosinophilic esophagitis (EoE) is a chronic, immune-mediated disease for which there is currently no pharmacologic therapy approved by the US Food and Drug Administration.

Methods: In this double-blind, placebo-controlled, phase 3 trial, patients aged 11-55 years with EoE and dysphagia were randomized 2:1 to receive budesonide oral suspension (BOS) 2.0 mg b. Read More

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A SWEET surprise: Anaerobic fungal sugar transporters and chimeras enhance sugar uptake in yeast.

Metab Eng 2021 Apr 19. Epub 2021 Apr 19.

Department of Chemical Engineering, University of California Santa Barbara, Santa Barbara, CA, 93106, USA; Joint BioEnergy Institute (JBEI), Emeryville, CA, 94608, USA. Electronic address:

In the yeast Saccharomyces cerevisiae, microbial fuels and chemicals production on lignocellulosic hydrolysates is constrained by poor sugar transport. For biotechnological applications, it is desirable to source transporters with novel or enhanced function from nonconventional organisms in complement to engineering known transporters. Here, we identified and functionally screened genes from three strains of early-branching anaerobic fungi (Neocallimastigomycota) that encode sugar transporters from the recently discovered Sugars Will Eventually be Exported Transporter (SWEET) superfamily into Saccharomyces cerevisiae. Read More

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Vancomycin Pre-soaking of ACL Tendon Grafts Is Highly Cost-Effective For Preventing Infection.

Arthroscopy 2021 Apr 19. Epub 2021 Apr 19.

Department of Orthopaedic Surgery, Tufts University Medical Center, Boston, Massachusetts, U.S.A.. Electronic address:

Purpose: This study aimed to (1) determine if intraoperative graft soaking with vancomycin is a cost-effective measure for preventing infection after arthroscopic ACL reconstruction and (2) provide an adaptable model for providers and institutions to determine the cost effectiveness of this strategy over a range of initial infection rates, infection-related care costs, and vancomycin costs.

Methods: Baseline postoperative infection rates, and the costs of antibiotics and infection-related care were gathered from the literature. The cost of treating infection was determined for two alternative protocols-irrigation and debridement with revision ACL reconstruction or ACL graft retention. Read More

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EPA and DHA differentially modulate membrane elasticity in the presence of cholesterol.

Biophys J 2021 Apr 19. Epub 2021 Apr 19.

Department of Biomedical Engineering, Northwestern University, Evanston, IL 60657, USA; Center for Synthetic Biology, Northwestern University, Evanston, IL 60657, USA. Electronic address:

Polyunsaturated fatty acids (PUFAs) modify the activity of a wide range of membrane proteins and are increasingly hypothesized to modulate protein activity by indirectly altering membrane physical properties. Among the various physical properties affected by PUFAs, the membrane area expansion modulus (K), which measures membrane strain in response to applied force, is expected to be a significant controller of channel activity. Yet the impact of PUFAs on membrane K has not been measured previously. Read More

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The Impact of Failed Antidepressant Trials on Outcomes in Children and Adolescents with Anxiety and Depression: A Systematic Review and Meta-Analysis.

J Child Adolesc Psychopharmacol 2021 Apr 21. Epub 2021 Apr 21.

Anxiety Disorders Research Program, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

To identify predictors of medication-placebo differences in double-blind placebo-controlled antidepressant trials in children and adolescents with anxiety and depression. Clinical trials in patients <18 years of age with major depressive disorder or generalized, separation or social anxiety disorders were obtained from PubMed, the Cochrane Database and clinicaltrials.gov searches from inception through 2019. Read More

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Disturbance type and species life history predict mammal responses to humans.

Glob Chang Biol 2021 Apr 22. Epub 2021 Apr 22.

Center for Integrated Spatial Research, University of California, Santa Cruz, California, 95064, USA.

Human activity and land use change impact every landscape on Earth, driving declines in many animal species while benefiting others. Species ecological and life history traits may predict success in human-dominated landscapes such that only species with "winning" combinations of traits will persist in disturbed environments. However, this link between species traits and successful coexistence with humans remains obscured by the complexity of anthropogenic disturbances and variability among study systems. Read More

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The Burden of Immune-Mediated Skin Disease in HIV/AIDS Inpatients.

Br J Dermatol 2021 Apr 22. Epub 2021 Apr 22.

Department of Dermatology, Stanford University, Palo Alto, California, USA.

Immune-mediated skin disease (IMSD) in human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) may manifest during acute infection, AIDS, or as part of immune reconstitution inflammatory syndrome. People living with HIV/AIDS have an increased incidence of psoriasis and eosinophilic folliculitis . Numerous other IMSDs have been described in the context of HIV/AIDS in case reports and series. Read More

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Love Anyway.

Authors:
Kari Beth Watts

Fam Med 2021 Apr;53(4):305-306

University of Illinois College of Medicine at Peoria, Department of Family and Community Medicine, Peoria, IL.

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Commentary: Smoking Is an Independent Risk Factor for 90-Day Readmission and Reoperation Following Posterior Cervical Decompression and Fusion.

Neurosurgery 2021 Apr 22. Epub 2021 Apr 22.

The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.

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The role of oxygen intake and liver enzyme on the dynamics of damaged hepatocytes: Implications to ischaemic liver injury via a mathematical model.

PLoS One 2021 22;16(4):e0230833. Epub 2021 Apr 22.

PRECESIONheor, Los Angeles, CA, United States of America.

Ischaemic Hepatitis (IH) or Hypoxic Hepatitis (HH) also known as centrilobular liver cell necrosis is an acute liver injury characterized by a rapid increase in serum aminotransferase. The liver injury typically results from different underlying medical conditions such as cardiac failure, respiratory failure and septic shock in which the liver becomes damaged due to deprivation of either blood or oxygen. IH is a potentially lethal condition that is often preventable if diagnosed timely. Read More

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Essential competencies for physical therapist managing individuals with spinal muscular atrophy: A delphi study.

PLoS One 2021 22;16(4):e0249279. Epub 2021 Apr 22.

Department of Rehabilitation, Columbia University Irving Medical Center, New York City, New York, United States of America.

Background And Purpose: With the availability and development of disease-modifying therapies for individuals with spinal muscular atrophy (SMA), new emerging phenotypes must be characterized, and potential new treatment paradigms tested. There is an urgent demand to develop an educational program that provides physical therapists (PTs) worldwide the necessary knowledge and training to contribute to best-practice care and clinical research. A competency based education framework is one that would focus on outcomes not process and where progression of learners would occur only after competencies are demonstrated. Read More

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Characterizing Healthcare Delays and Interruptions in the US During the COVID-19 Pandemic: Data from an Internet-Based Cross-Sectional Survey.

J Med Internet Res 2021 Apr 20. Epub 2021 Apr 20.

Columbia University, New York, US.

Background: The COVID-19 pandemic has broader geographic spread and potentially longer lasting effects than previous disasters. Necessary preventive precautions for the transmission of COVID-19 resulted in delays of in-person healthcare services, especially at the outset of the pandemic.

Objective: Among a US sample, we examined the rates of delays (defined as cancellations and postponements) to healthcare at the outset of the pandemic and characterized the reasons for delays. Read More

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Position Statement: Mass Gathering Medical Care.

Prehosp Emerg Care 2021 Apr 22:1-4. Epub 2021 Apr 22.

Division of Emergency Medicine, University of Chicago School of Medicine, Chicago, Illinois, USA.

The National Association of EMS Physicians (NAEMSP) recognizes the continued growth and complexity of mass gathering events and the integral role of the medical director in their planning and management. There is a growing body of literature that provides additional insight into patient presentations as well as preparation, staffing, and planning for these events. The clinical practice of EMS medicine encompasses the provision of care in a variety of out-of-hospital environments, including those defined as mass gathering events. Read More

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Realization of Electron Antidoping by Modulating the Breathing Distortion in BaBiO.

Nano Lett 2021 Apr 22. Epub 2021 Apr 22.

School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.

The recent proposal of antidoping scheme breaks new ground in conceiving conversely functional materials and devices; yet, the few available examples belong to the correlated electron systems. Here, we demonstrate both theoretically and experimentally that the main group oxide BaBiO is a model system for antidoping using oxygen vacancies. The first-principles calculations show that the band gap systematically increases due to the strongly enhanced Bi-O breathing distortions away from the vacancies and the annihilation of Bi 6/O 2 hybridized conduction bands near the vacancies. Read More

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Nanoparticles Interfere with Chemotaxis: An Example of Nanoparticles as Molecular "Knockouts" at the Cellular Level.

ACS Nano 2021 Apr 22. Epub 2021 Apr 22.

Department of Chemistry, University of Illinois at Urbana-Champaign, 600 S. Mathews Avenue, Urbana, Illinois 61801, United States.

Engineered colloidal nanoparticles show great promise in biomedical applications. While much of the work of assessing nanoparticle impact on living systems has been focused on the direct interactions of nanoparticles with cells/organisms, indirect effects the extracellular matrix have been observed and may provide deeper insight into nanoparticle fate and effects in living systems. In particular, the large surface area of colloidal nanoparticles may sequester molecules from the biological milieu, make these molecules less bioavailable, and therefore function indirectly as "molecular knockouts" to exert effects at the cellular level and beyond. Read More

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Reevaluation of Poly(ethylene--propylene)--Polydimethylsiloxane Phase Behavior Uncovers Topological Close-Packing and Epitaxial Quasicrystal Growth.

ACS Nano 2021 Apr 22. Epub 2021 Apr 22.

Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota 55455, United States.

Reanalysis of an asymmetric poly(ethylene--propylene)--polydimethylsiloxane (PEP-PDMS) diblock copolymer first investigated in 1999 has revealed a rich phase behavior including a dodecagonal quasicrystal (DDQC), a Frank-Kasper σ phase, and a body-centered cubic (BCC) packing at high temperature adjacent to the disordered state. On subjecting the sample to large amplitude oscillatory shear well below the σ-BCC order-order transition temperature (), small-angle X-ray scattering evidenced the emergence of a twinned BCC phase that, on heating, underwent a phase transition to an unusually anisotropic DDQC state. Surprisingly, we observe no evidence of this apparent epitaxy on heating or cooling through the equilibrium σ-BCC transition. Read More

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Ammonia Capture within Zirconium Metal-Organic Frameworks: Reversible and Irreversible Uptake.

ACS Appl Mater Interfaces 2021 Apr 22. Epub 2021 Apr 22.

Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United States.

Ammonia uptake by high-capacity and high-porosity sorbents is a promising approach to its storage and release, capture and mitigation, and chemical separation. Here, we examined the ammonia sorption behavior of several versions of an archetypal zirconium-based metal-organic framework (MOF) material, NU-1000-a meso- and microporous crystalline compound having the empirical formula (1,3,6,8-tetrakis(-benzoate)pyrene) Zr(μ-O)(μ-OH)(HO)(OH) with linkers and nodes arranged to satisfy a topology. Depending on the thermal treatment protocol used prior to sorption measurements, ammonia can physisorb to NU-1000 via hydrogen-bonding and London-dispersion interactions and chemisorb via Brønsted acid-base reactions with node-integrated proton donors (μ-hydroxos) and node-ligated proton donors (terminal hydroxos), via simple coordination at open Zr(IV) sites, or via dissociative coordination to Zr(IV) as NH and protonation of a node-based μ-oxo. Read More

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Understanding Risk Factors for Persistent Opioid Use Among Youths.

JAMA Netw Open 2021 Apr 1;4(4):e214904. Epub 2021 Apr 1.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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Presence-Absence Sampling Plans for Stink Bugs (Hemiptera: Pentatomidae) in the Midwest Region of the United States.

J Econ Entomol 2021 Apr 22. Epub 2021 Apr 22.

Department of Entomology, University of Minnesota, Saint Paul, MN, USA.

Stink bugs represent an increasing risk to soybean production in the Midwest region of the United States. The current sampling protocol for stink bugs in this region is tailored for population density estimation and thus is more relevant to research purposes. A practical decision-making framework with more efficient sampling effort for management of herbivorous stink bugs is needed. Read More

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Cost-reducing traits for agonistic head collisions: a case for neurophysiology.

Integr Comp Biol 2021 Apr 22. Epub 2021 Apr 22.

Brown University, Providence, RI USAMJF.

Many animal species have evolved extreme behaviors requiring them to engage in repeated high-impact collisions. These behaviors include mating displays like headbutting in sheep and drumming in woodpeckers. To our knowledge, these taxa do not experience any notable acute head trauma, even though the deceleration forces would cause traumatic brain injury in most animals. Read More

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Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study.

JAMA Pediatr 2021 Apr 22. Epub 2021 Apr 22.

Nuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, United Kingdom.

Importance: Detailed information about the association of COVID-19 with outcomes in pregnant individuals compared with not-infected pregnant individuals is much needed.

Objective: To evaluate the risks associated with COVID-19 in pregnancy on maternal and neonatal outcomes compared with not-infected, concomitant pregnant individuals.

Design, Setting, And Participants: In this cohort study that took place from March to October 2020, involving 43 institutions in 18 countries, 2 unmatched, consecutive, not-infected women were concomitantly enrolled immediately after each infected woman was identified, at any stage of pregnancy or delivery, and at the same level of care to minimize bias. Read More

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Remote Research and Clinical Trial Integrity During and After the Coronavirus Pandemic.

JAMA 2021 Apr 22. Epub 2021 Apr 22.

Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.

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Evaluation of Safety of Stereotactic Body Radiotherapy for the Treatment of Patients With Multiple Metastases: Findings From the NRG-BR001 Phase 1 Trial.

JAMA Oncol 2021 Apr 22. Epub 2021 Apr 22.

Ohio State University Comprehensive Cancer Center, Columbus.

Importance: Stereotactic body radiotherapy (SBRT) for oligometastases is hypothesized to improve survival and is increasingly used. Little evidence supports its safe use to treat patients with multiple metastases.

Objective: To establish safety of SBRT dose schedules in patients with 3 to 4 metastases or 2 metastases in close proximity to each other. Read More

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Assessing Practices, Beliefs, and Attitudes about Palliative Care among People with Cystic Fibrosis, Their Caregivers, and Clinicians: Results of a Content Analysis.

J Palliat Med 2021 Apr 20. Epub 2021 Apr 20.

Emory University, Atlanta, Georgia, USA.

Individuals with cystic fibrosis (CF) experience symptoms affecting quality of life and may benefit from palliative care (PC). To present results of content analysis from open-ended survey questions assessing knowledge and experiences with PC among CF stakeholders. Online surveys were sent to CF stakeholders through CF-specific listservs predominantly in the United States. Read More

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Food insecurity associated with elevated eating disorder symptoms, impairment, and eating disorder diagnoses in an American University student sample before and during the beginning of the COVID-19 pandemic.

Int J Eat Disord 2021 Apr 22. Epub 2021 Apr 22.

Department of Psychology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Objective: This study tested the association between food insecurity and eating disorder (ED) pathology, including probable ED diagnosis, among two cohorts of university students before and during the beginning of the COVID-19 pandemic.

Method: Students (n = 579) from a large Midwestern American university completed self-report questionnaires assessing frequency of ED behaviors, ED-related impairment, and individual food insecurity as measured by the Eating Disorder Diagnostic Scale 5, Clinical Impairment Assessment, and Radimer/Cornell, respectively. Chi-square tests and MANOVA with post-hoc corrections were conducted to compare demographic characteristics, ED pathology, and probable ED diagnosis prevalence between students with and without individual food insecurity. Read More

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Pattern of Cumulative Treatment Hours on Pain Impact and PROMIS Outcomes.

Mil Med 2021 Apr 22. Epub 2021 Apr 22.

Department of Biobehavioral Nursing Science, College of Nursing, University of Illinois at Chicago, Chicago, IL 60607, USA.

Introduction: Participation in interdisciplinary treatments is associated with improvement in pain intensity, physical function, and additional pain-related outcome domains. However, the effect of cumulative treatment hours on outcomes remains unknown among military patients. The present analysis examined the relationship between cumulative interdisciplinary treatment hours and pain management outcomes at a single interdisciplinary pain management center (IPMC). Read More

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Estimating optimal willingness to pay thresholds for cost-effectiveness analysis: A generalized method.

Health Econ 2021 Apr 21. Epub 2021 Apr 21.

CNO Financial Group, Chicago, Illinois, USA.

Operationalizing cost-effectiveness analysis (CEA) requires that decisionmakers select maximum willingness to pay thresholds (K). We generalize previous methods used to estimate K using highly flexible hyperbolic absolute risk aversion (HARA) utility functions that encompass a wide range of risk behavior. For HARA utility, we calculate formulas for relative risk aversion (r*) and relative prudence (π ), using literature-based estimates to calibrate our HARA model. Read More

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It's Been a Long Journey: Do We Know Where We Are Going?

J Med Toxicol 2021 Apr 21. Epub 2021 Apr 21.

Toxikon Consortium, Division of Toxicology, Department of Emergency Medicine, Cook County Health, 1950 West Polk Street, 7th floor, Chicago, IL, 60612, USA.

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