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Merging N-hydroxyphthalimide into Metal-Organic Frameworks for Highly Efficient and Environmentally Benign Aerobic Oxidation.

Chemistry 2021 May 10. Epub 2021 May 10.

Tongji University, School of Chemical Science and Engineering, Chifeng Road No.67, Shanghai, CHINA.

Two highly efficient metal-organic framework catalysts TJU-68-NHPI and TJU-68-NDHPI have been successfully synthesized through solvothermal reactions of which the frameworks are merged with N-hydroxyphthalimide (NHPI) units for the first time, resulting in the decoration of pore surfaces with highly active nitroxyl catalytic sites. When t-butyl nitrite (TBN) is used as co-catalyst, the as synthesized MOFs are demonstrated to be highly efficient and recyclable catalysts for a novel three-phase heterogeneous oxidation of activated C-H bond of primary, secondary alcohols and benzyl compounds under mild conditions. Based on the high efficiency and selectivity, an environmental benign system with good sustainability, mild condition, simple work-up procedure has been established for practical oxidation of a wide range of substrates. Read More

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Burn Center Organization & Cellular Therapy Integration: Managing Risks and Costs.

J Burn Care Res 2021 May 10. Epub 2021 May 10.

Plastic, Reconstructive and Hand Surgery Service, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.

The complex management of severe burn victims requires an integrative collaboration of multidisciplinary specialists in order to ensure quality and excellence in healthcare. This multidisciplinary care has quickly led to the integration of cell therapies in clinical care of burn patients. Specific advances in cellular therapy together with medical care have allowed for rapid treatment, shorter residence in hospitals and intensive care units, shorter durations of mechanical ventilation, lower complications and surgery interventions, and decreasing mortality rates. Read More

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Homicides of black people in Brazil: A study of different regions, using generalized additive regression models-with a geo-spatial component.

Geospat Health 2021 May 5;16(1). Epub 2021 May 5.

Federal University of Technology, Paraná (UTFPR), Cornélio Procópio city (PR).

The number of homicides in Brazil has reached record numbers, and when the race/colour of the victims is considered-an extreme inequality is evident- with a particularly high number of deaths in black and brown populations. The goal of this work was to analyse homicide rates of black people in Brazil from the years 2000 to 2016, using generalized additive regression models, with a geo-spatial component. The statistics were applied to understand the social reasons for homicide risks in the black population in Brazil's 26 states and Federal District with reference to the human development index and its components (education, longevity and income) as well as social inequality indices (Gini and Theil). Read More

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Surge in calls to Irish Skin Foundation's 'Ask a nurse' helpline during Covid.

Clin Exp Dermatol 2021 May 10. Epub 2021 May 10.

Irish Skin Foundation, Charles Institute for Dermatology, University College Dublin, Dublin, D04 V1W8, Ireland.

The Irish Skin Foundation (ISF) is a national charity dedicated to improving quality of life for people living with skin conditions. The ISF offers a unique 'Ask a Nurse' helpline service delivered by Dermatology Clinical Nurse Specialists, all of whom work in clinical practice, in hospital dermatology units in Ireland, and are up to date with best practice/current treatments. The ISF 'Ask a nurse' helpline has provided a valuable service (as evidenced by the 97% user satisfaction rating since the service was set up in 2016) in addressing the concerns of callers and supporting patients; and even more so during the Covid-19 pandemic. Read More

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Non-domestic wastewater treatment with fungal/bacterial consortium followed by sp., and thermal conversion of the generated sludge.

3 Biotech 2021 May 20;11(5):227. Epub 2021 Apr 20.

Laboratorio de Microbiología Ambiental y de Suelos, Unidad de Investigaciones Agropecuarias (UNIDIA), Departamento de Microbiología. Pontificia Universidad Javeriana, Carrera 7ma No 43-82, Edifício 50 Lab. 106, Código Postal 110-23 Bogotá DC, Colombia.

Liquid waste from biological stains is considered non-domestic wastewater difficult to treat, generating high environmental impact. Therefore, the objective of this work was to carry out secondary and tertiary treatment of these effluents at a pilot scale, using a fungal/bacterial consortium followed by sp., for 15 days. Read More

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The prevalence of exposure to potentially morally injurious events among physicians during the COVID-19 pandemic.

Eur J Psychotraumatol 2021 Apr 16;12(1):1898791. Epub 2021 Apr 16.

Faculty of Psychology and Educational Sciences, "Alexandru Ioan Cuza" University, Iasi, Romania.

: Given the profound psychological distress caused by the Covid-19 pandemic, healthcare workers are at high risk of being exposed to potentially morally injurious events (PMIEs). : We aimed to explore the prevalence and associated factors with PMIEs in a sample of Romanian physicians, of which almost half worked in Covid-19 treatment medical units. : We ran a web-based survey in April 2020, three weeks after the general lockdown to contain the novel coronavirus. Read More

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Determination of COVID-19 pneumonia based on generalized convolutional neural network model from chest X-ray images.

Expert Syst Appl 2021 Oct 4;180:115141. Epub 2021 May 4.

Akdeniz University, Vocational School of Health Services, Department of Medical Imaging Techniques, Antalya 07070, Turkey.

X-ray units have become one of the most advantageous candidates for triaging the new Coronavirus disease COVID-19 infected patients thanks to its relatively low radiation dose, ease of access, practical, reduced prices, and quick imaging process. This research intended to develop a reliable convolutional-neural-network (CNN) model for the classification of COVID-19 from chest X-ray views. Moreover, it is aimed to prevent bias issues due to the database. Read More

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October 2021

American Medical Society for Sports Medicine sports ultrasound curriculum for sports medicine fellowships.

Br J Sports Med 2021 May 9. Epub 2021 May 9.

Emergency Medicine, The University of Arizona College of Medicine Tucson, Tucson, Arizona, USA.

Sports ultrasound is commonly used by sports medicine physicians to enhance diagnostic and procedural accuracy. This expert consensus statement serves as an update to the 2015 American Medical Society for Sports Medicine recommended sports ultrasound curriculum for sports medicine fellowships. Although written in the context of the American sports medicine fellowship training model, we present a stepwise progression in both diagnostic and interventional sports ultrasound that may be applicable to the broader sports medicine community. Read More

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Region-level epimutation rates in Arabidopsis thaliana.

Heredity (Edinb) 2021 May 8. Epub 2021 May 8.

Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany.

Failure to maintain DNA methylation patterns during plant development can occasionally give rise to so-called "spontaneous epimutations". These stochastic methylation changes are sometimes heritable across generations and thus accumulate in plant genomes over time. Recent evidence indicates that spontaneous epimutations have a major role in shaping patterns of methylation diversity in plant populations. Read More

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Advanced characterization of polyphenols from Myrciaria jaboticaba peel and lipid protection in in vitro gastrointestinal digestion.

Food Chem 2021 Apr 27;359:129959. Epub 2021 Apr 27.

INRAE, Avignon University, UMR408 SQPOV, F-84000 Avignon, France. Electronic address:

Ultrasound-assisted and solvent extractions resulted in similar levels of hydrolyzable tannins (10.3-6.0 mg/g), anthocyanins (7. Read More

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Breastfeeding knowledge in university nursing students. A multicentre study in Spain.

Nurse Educ Today 2021 May 4;103:104945. Epub 2021 May 4.

Nursing Department, Universitat Jaume I, Avda Sos Baynat s/n, 12071 Castellón, Spain. Electronic address:

Background: Exclusive breastfeeding is one of the main health and infant survival elements. To start and maintain breastfeeding, health professionals must receive culturally sensitive evidence-based breastfeeding training to offer future mothers the required information and support. While studying the nursing degree, acquiring the necessary knowledge and skills to successfully perform this work is essential. Read More

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Organic carbon bioavailability: Is it a good driver to choose the best biological nitrogen removal process?

Sci Total Environ 2021 Apr 29;786:147390. Epub 2021 Apr 29.

Western Paraná State University, 85819-110 Cascavel, PR, Brazil; Federal University of Fronteira Sul, 99700-000 Erechim, Brazil; Embrapa Suínos e Aves, 89715-899 Concórdia, SC, Brazil. Electronic address:

Organic carbon can affect the biological nitrogen removal process since the Anammox, heterotrophic and denitrifying bacteria have different affinities and feedback in relation to carbon/nitrogen ratio. Therefore, we reviewed the wastewater carbon concentration, its biodegradability and bioavailability to choose the appropriate nitrogen removal process between conventional (nitrification-denitrification) and Anammox-based process (i.e. Read More

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"We can't just have a casual conversation": An institutional ethnography-informed study of work in labour and birth.

Soc Sci Med 2021 Apr 29;279:113975. Epub 2021 Apr 29.

Wilson Centre for Research in Education, University Health Network, University of Toronto, Canada; University of Toronto's Centre for Interprofessional Education, University Health Network, Canada; Department of Speech-Language Pathology, University of Toronto, Canada.

Labour and delivery units often become contested workplaces with tensions between obstetrics, nursing, and midwifery practices. These tensions can impede communication and raise concerns about provider wellness and patient safety. Remedying such tensions requires inquiry into the drivers of recurrent problems in interprofessional practice. Read More

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Exploring the influence of impact severity and posture on vertebral joint mechanics in an in-vitro porcine model.

J Biomech 2021 Apr 25;122:110479. Epub 2021 Apr 25.

Department of Kinesiology, University of Waterloo, Waterloo, ON, Canada. Electronic address:

To date, no in vitro studies have been conducted to explore lumbar soft tissue injury potential and altered mechanical properties from exposure to impact forces. After a motor vehicle collision (MVC), the cause of reported acute onset low back pain is difficult to associate with potential soft tissue strain injury sites including the facet joint and innervated facet joint capsule ligament (FJC). Thus, the purpose of this investigation was to quantify intervertebral anterior-posterior (AP) translation and facet joint capsule strain under varying postures and impact severities. Read More

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Interdependencies between Toll-Like Receptors in Leishmania infection.

Immunology 2021 May 8. Epub 2021 May 8.

Tripura University, Agartala, Tripura, India.

Multiple pathogen-associated molecular patterns (PAMPs) on a pathogen's surface imply their simultaneous recognition by the host cell membrane-located multiple PAMP-specific Toll-Like Receptors (TLRs). The TLRs on endosomes recognize internalized pathogen-derived nucleic acids and trigger anti-pathogen immune responses aimed at eliminating the intracellular pathogen. Whether the TLRs influence each others expression and effector responses- termed TLRs inter-dependency- remains unknown. Read More

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Exceptional Cocatalyst-Free Photo-Enhanced Piezocatalytic Hydrogen Evolution of Carbon Nitride Nanosheets from Strong In-Plane Polarization.

Adv Mater 2021 May 8:e2101751. Epub 2021 May 8.

Beijing Key Laboratory of Materials Utilization of Nonmetallic Minerals and Solid Wastes, National Laboratory of Mineral Materials, School of Materials Science and Technology, China University of Geosciences, Beijing, 100083, China.

Utilizing mechanical energy to produce hydrogen is emerging as a promising way to generate renewable energy, but is challenged by low efficiency and scanty cognition. In this work, graphitic carbon nitride (g-C N ) with an atomically thin sheet-like structure is applied for prominent piezocatalytic and photo-enhanced piezocatalytic H production. It is revealed that the anomalous piezoelectricity in g-C N originates from the strong in-plane polarization along the a-axis, contributed by the superimposed polar tri-s-triazine units and flexoelectric effect derived from the structured triangular cavities, which provides powerful electrochemical driving force for the water reduction reaction. Read More

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Transfusion support during childbirth for a woman with anti-U and the allele.

Immunohematology 2021 Mar;37(1):1-4

Laboratory Services Section, Department of Transfusion Medicine, NIH Clinical Center, National Institutes of Health , 10 Center Drive, Bethesda, MD 20892.

D- red blood cells (RBCs), always in short supply, and Rh immune globulin (RhIG) are not needed for patient care if D+ RBCs can safely be transfused. According to a recent work group recommendation, patients with the allele can be considered D+. We report an African American woman who presented for delivery at the end of the third trimester, at which time anti-U and a serologic weak D phenotype were recognized, requiring U-, D- RBC units. Read More

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Venous Thromboembolism among Noncritically Ill Hospitalized Children: Key Considerations for the Pediatric Hospital Medicine Specialist.

Semin Thromb Hemost 2021 May 7. Epub 2021 May 7.

Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Venous thromboembolism (VTE) is a leading cause of morbidity and preventable harm among noncritically ill hospitalized children. Several clinical factors relevant to the noncritically ill hospitalized child significantly increase the risk of VTE including the presence of central venous catheters, systemic inflammation, and prolonged immobilization. Although risk mitigation strategies have been described, the diagnosis, treatment, and prevention of VTE require standardization of institutional practices combined with multidisciplinary collaboration among pediatric hospitalists, hematologists, and other care providers. Read More

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Higher 1-year mortality in women admitted to intensive care units after cardiac arrest: A nationwide overview from the Netherlands between 2010 and 2018.

J Crit Care 2021 Apr 17;64:176-183. Epub 2021 Apr 17.

Department of Intensive Care, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Cardiology, Erasmus University Medical Center, Rotterdam, the Netherlands.

Purpose: We study sex differences in 1-year mortality of out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA) patients admitted to the intensive care unit (ICU).

Data: A retrospective cohort analysis of OHCA and IHCA patients registered in the NICE registry in the Netherlands. The primary and secondary outcomes were 1-year and hospital mortality, respectively. Read More

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Knowledge, attitude, and practice of nurses in intensive care unit on preventing medical device-related pressure injury: A cross-sectional study in western China.

Int Wound J 2021 May 7. Epub 2021 May 7.

School of Nursing, Lanzhou University, Lanzhou, Gansu, People's Republic of China.

The knowledge, attitude, and practice of nurses in intensive care units (ICUs) are determinants for the efficacy of preventing the medical device-related pressure injury (MDRPI). The aim of this study was to determine the level and factors of knowledge, attitude, and practice of nurses' ICUs on preventing medical MDRPI in western China. An annual cross-sectional study was conducted in hospitals of western China from May 2020 to September 2020. Read More

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Sharing a written medical summary with patients on the post-admission ward round: A qualitative study of clinician and patient experience.

J Eval Clin Pract 2021 May 7. Epub 2021 May 7.

THIS Institute (The Healthcare Improvement Studies Institute), University of Cambridge Clinical School, Cambridge, UK.

Rationale, Aims And Objectives: Sharing aspects of the traditional medical record with patients has been successful in primary and antenatal care, but has not been investigated in the UK inpatient setting. Our aim was to evaluate the impact on patient and clinician experience of providing patients with a written lay summary of their care-plan in the acute care setting.

Method: We carried out a qualitative interview study on two acute medicine wards in an NHS University Teaching Hospital for a 4-week period in 2019. Read More

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Wind tunnel-based testing of a photoelectrochemical oxidative filter-based air purification unit in coronavirus and influenza aerosol removal and inactivation.

Indoor Air 2021 May 7. Epub 2021 May 7.

Department of Mechanical Engineering, College of Science and Engineering, University of Minnesota, Minneapolis, MN, USA.

Recirculating air purification technologies are employed as potential means of reducing exposure to aerosol particles and airborne viruses. Toward improved testing of recirculating air purification units, we developed and applied a medium-scale single-pass wind tunnel test to examine the size-dependent collection of particles and the collection and inactivation of viable bovine coronavirus (BCoV, a betacoronavirus), porcine respiratory coronavirus (PRCV, an alphacoronavirus), and influenza A virus (IAV), by a commercial air purification unit. The tested unit, the Molekule Air Mini, incorporates a MERV 16 filter as well as a photoelectrochemical oxidating layer. Read More

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Self-assembly of Amphiphilic Porphyrins to Construct Nanoparticles for Highly Efficient Photodynamic Therapy.

Chemistry 2021 May 7. Epub 2021 May 7.

Chinese Academy of Sciences, Techn. Inst. Phys & Chem, No.29, Zhongguancun East Road, Haidian District, 100190, Beijing, CHINA.

Hydrophobic photosensitizers greatly affect the cell permeability and enrichment in tumours. They cannot be used directly for clinical applications because they always reunite in water, preventing their circulation in the blood and accumulation in tumour cells. As a result, amphiphilic photosensitizers are highly desirable. Read More

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Supply-chain strategies for essential medicines in rural western Kenya during COVID-19.

Bull World Health Organ 2021 May 10;99(5):388-392. Epub 2021 Feb 10.

Department of Population Health, New York University Grossman School of Medicine, New York, USA.

Problem: The coronavirus disease 2019 (COVID-19) pandemic has disrupted health systems worldwide and threatened the supply of essential medicines. Especially affected are vulnerable patients in low- and middle-income countries who can only afford access to public health systems.

Approach: Soon after physical distancing and curfew orders began on 15 March 2020 in Kenya, we rapidly implemented three supply-chain strategies to ensure a continuous supply of essential medicines while minimizing patients' COVID-19 exposure risks. Read More

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American Medical Society for Sports Medicine Sports Ultrasound Curriculum for Sports Medicine Fellowships.

Clin J Sport Med 2021 May 11. Epub 2021 May 11.

Departments of Orthopedics & Rehabilitation, Radiology, and Family Medicine, University of Iowa Sports Medicine, Iowa City, Iowa; Departments of Pediatrics and Orthopedics and Rehabilitation, University of Wisconsin, Madison, Wisconsin; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota; Departments of Orthopedics and Radiology, Essentia Health, Duluth, Minnesota; Rothman Orthopaedics New York, New York, New York; Department of Orthopedics and Physical Medicine and Rehabilitation, Emory University, Atlanta, Georgia; Department of Family Medicine, University of Washington, Seattle, Washington; Departments of Emergency Medicine and Physical Medicine and Rehabilitation, University of California, Davis, Davis, California; Departments of Physical Medicine and Rehabilitation, Radiology, and Clinical Anatomy, Mayo Clinic College of Medicine, Rochester, Minnesota; and Department of Emergency Medicine, The University of Arizona, Tucson, Arizona.

Abstract: Sports ultrasound is commonly used by sports medicine physicians to enhance diagnostic and procedural accuracy. This expert consensus statement serves as an update to the 2015 American Medical Society for Sports Medicine recommended sports ultrasound curriculum for sports medicine fellowships. Although written in the context of the American sports medicine fellowship training model, we present a stepwise progression in both diagnostic and interventional sports ultrasound that may be applicable to the broader sports medicine community. Read More

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The Financial Implications of Telehealth Visits Within a Hand and Wrist Surgery Clinical Practice During the COVID-19 Pandemic.

J Hand Surg Am 2021 Apr 6. Epub 2021 Apr 6.

Rothman Orthopaedic Institute, Philadelphia, PA; Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA. Electronic address:

Purpose: Telehealth use is likely to increase as a result of practice changes during the COVID-19 pandemic, although the overall picture surrounding the billing, coding, and continued insurance coverage of these visits remains uncertain. The purpose of this study was to identify potential financial implications of continued telehealth use in hand and wrist surgery clinical practice.

Methods: Two hundred telehealth visits were randomly selected and matched 1:1 based on primary diagnosis code to in-person visits. Read More

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Evaluation of the Relationship Between Aspects of Medical Complexity and Work Relative Value Units (wRVUs) for Foot and Ankle Surgical Procedures.

J Foot Ankle Surg 2021 May-Jun;60(3):448-454. Epub 2020 Jul 3.

Clinical Associate Professor, Department of Podiatric Surgery, Temple University School of Podiatric Medicine, Philadelphia, Pennsylvania.

Work relative value units (wRVUs) have been assigned to current procedural terminology codes in an effort to help establish physician compensation. However, the ability of these to accurately and efficiently capture the time, technical, and perioperative managerial aspects required of various procedures has recently been called into question for several surgical subspecialties. Therefore, the objective of this investigation was to evaluate various measures of medical complexity against wRVUs for foot and ankle surgical procedures. Read More

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Enhanced diversity and rock-weathering potential of bacterial communities inhabiting potash trachyte surface beneath mosses and lichens - A case study in Nanjing, China.

Sci Total Environ 2021 Apr 26;785:147357. Epub 2021 Apr 26.

Key Laboratory of Agricultural and Environmental Microbiology, Ministry of Agriculture, College of Life Science, Nanjing Agricultural University, Nanjing 210095, PR China.

Mosses and lichens have been shown to play an important role in enhancing global chemical weathering of the surface rock. However, there are no studies concerning the effects of mosses and lichens on the microbial communities inhabiting rock surfaces. In this study, culture-dependent and culture-independent analyses were employed to compare the diversity, composition, and rock-weathering activity of bacterial communities inhabiting potash trachyte surfaces covered by mosses (MR) and lichens (LR) with those inhabiting surrounding bare rock surfaces (BR). Read More

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Development of the fluorescent carbon nanosensor for pH and temperature of liquid media with artificial neural networks.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 21;258:119861. Epub 2021 Apr 21.

Department of Physics, Lomonosov Moscow State University, Moscow 119991, Russia; Skobeltsyn Institute of Nuclear Physics, Lomonosov Moscow State University, Moscow 119991, Russia.

The present study is devoted to the creation of optical nanosensors for pH and temperature of liquid media based on carbon dots (CD) prepared via hydrothermal synthesis. The application of artificial neural networks to the CD fluorescence spectra database provided simultaneous determination of pH and ambient temperature values with an accuracy of 0.005 pH units and 0. Read More

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