34,080 results match your criteria unique complications

Splenic Injury After a Colonoscopy: Threading the Scope Carefully in Heritable Connective Tissue Disorders.

Cureus 2021 Jun 4;13(6):e15444. Epub 2021 Jun 4.

Gastroenterology and Hepatology, Ascension Genesys Hospital, Grand Blanc, USA.

Colonoscopies have reduced colorectal cancer (CRC) burden in the United States, and their utility has expanded to include various diagnostic and therapeutic indications. Complications are seen in up to 1% and increase with age and polypectomy. As colonoscopies become widespread, specific populations seem to be at a much higher risk; notably patients with heritable connective tissue disorders (HCTD). Read More

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Helping the Surgeon Recover: Peer-to-Peer Coaching after Bile Duct Injury.

J Am Coll Surg 2021 May 21. Epub 2021 May 21.

Temerty Faculty of Medicine, University of Toronto, Toronto, Canada; Division of General Surgery, University of Toronto, Toronto, Canada; HPB Service, St. Joseph's Health Centre, Unity Health Toronto, Toronto, Canada. Electronic address:

Background: Bile duct injury sustained during laparoscopic cholecystectomy is associated with high morbidity and mortality and can be a devastating complication for a General Surgeon. We introduce a novel individualized surgical coaching program for surgeons who recently injured a bile duct in laparoscopic cholecystectomy. We aim to explore the perception of coaching among these surgeons and to assess surgeons' experiences in the coaching program. Read More

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Case report: iatrogenic left ventricular outflow tract to right atrium fistula after trans-femoral transcatheter aortic valve implantation associated with asymmetric septal hypertrophy.

Eur Heart J Case Rep 2021 Mar 10;5(3):ytab020. Epub 2021 Mar 10.

Department of Cardiology, University Hospital of Brest, Tanguy Prigent Boulevard, 29609 Brest Cedex, France.

Background : The transcatheter aortic valve implantation (TAVI) is becoming a leading treatment option for symptomatic aortic stenosis for patients in all surgical risk categories. Recognition and management of potential complications are essential to ensure patient life and comfort. We present here a case report of a left ventricular outflow tract (LVOT) to right atrium (RA) fistula which is an extremely rare complication after TAVI. Read More

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Radiological anatomy of the intracranial vertebral artery in a select South African cohort of patients.

Sci Rep 2021 Jun 9;11(1):12138. Epub 2021 Jun 9.

Discipline of Clinical Anatomy, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4000, South Africa.

The intracranial segment of the vertebral artery (VA) is the unique part of the artery where the two VAs join to form a single vascular channel, viz. the basilar artery. In addition to this typical description, anatomical variations have been described; the presence of anatomical variation has been associated with some pathological processes, neurological complications, and the risk of vascular diseases in the posterior circulatory territory. Read More

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Cultural Complications Curriculum: Applicability to Surgical Oncology Programs and Practices.

Ann Surg Oncol 2021 Jun 9. Epub 2021 Jun 9.

Department of Surgery, University of Maryland Medical Center, Baltimore, MD, USA.

Background: Recognizing the need to raise awareness of core diversity, equity, and inclusion (DEI) issues in the healthcare system, our previously developed Cultural Complications Curriculum aims to support institutions in reducing cultural error. As we continue program deployment, we discuss the opportunity to apply the Cultural Complications Curriculum to multidisciplinary audiences, such as in cancer programs.

Methods: We discuss applicability of the Cultural Complications Curriculum to cancer programs and practices, including how to tailor case discussions to oncology audiences. Read More

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Epidemiology of Pars Plana Vitrectomy in the Elderly: A Retrospective 10-Year Survey of 592 Cases.

Clin Interv Aging 2021 1;16:1007-1012. Epub 2021 Jun 1.

Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel.

Purpose: To report the epidemiology of the surgical indications of pars plana vitrectomy in patients aged 75 years or older.

Patients And Methods: The medical records of patients who underwent vitrectomy surgery in a single center between 2008 and 2018 were evaluated retrospectively for demographics, medical background, and surgical indications. Data on patients aged 75-85 were compared to those of patients older than 85 years and those recorded between 2008-2013 and 2014-2018. Read More

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Informed Consent and Informed Decision-Making in High-Risk Surgery: A Quantitative Analysis.

J Am Coll Surg 2021 Jun 5. Epub 2021 Jun 5.

University of Wisconsin School of Medicine and Public Health, Department of Surgery, Madison, WI.

Background: Informed consent is an ethical and legal requirement that differs from informed decision-making-a collaborative process that fosters participation and provides information to help patients reach treatment decisions. The objective of this study was to measure informed consent and informed decision-making prior to major surgery.

Methods: We audio-recorded 90 preoperative patient-surgeon conversations prior to major cardiothoracic, vascular, oncologic, and neurosurgical procedures at 3 centers in the U. Read More

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Understanding context: A qualitative analysis of the roles of family caregivers of people living with cancer in Vietnam and the implications for service development in low-income settings.

Psychooncology 2021 Jun 8. Epub 2021 Jun 8.

School of Nursing and Midwifery, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road Belfast.

Objectives: Research on the needs of family caregivers of people living with cancer remains disproportionately focused in high income contexts. This research gap adds to the critical challenge on global equitable delivery of cancer care. This study describes the roles of family caregivers of people living with cancer in Vietnam and possible implications for intervention development. Read More

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Preoperative Cardiopulmonary Exercise Test Associated with Postoperative Outcomes in Patients Undergoing Cancer Surgery: A Systematic Review and Meta-Analyses.

Ann Surg Oncol 2021 Jun 8. Epub 2021 Jun 8.

Surgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital (RPAH), Sydney, NSW, Australia.

Backgrounds: There is mixed evidence on the value of preoperative cardiorespiratory exercise test (CPET) to predict postoperative outcomes in patients undergoing a cancer surgical procedure. The purpose of this review was to investigate the association between preoperative CPET variables and postoperative complications, length of hospital stay, and quality of life in patients undergoing cancer surgery.

Methods: A search was conducted on MEDLINE, Embase, AMED, and Web of science from inception to April 2020. Read More

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Imaging retinal microvascular manifestations of carotid artery disease in older adults: from diagnosis of ocular complications to understanding microvascular contributions to cognitive impairment.

Geroscience 2021 Jun 8. Epub 2021 Jun 8.

Department of Ophthalmology, Semmelweis University, 39 Mária Street, 1085, Budapest, Hungary.

Carotid artery stenosis (CAS) is a consequence of systemic atherosclerotic disease affecting the aging populations of the Western world. CAS is frequently associated with cognitive impairment. However, the mechanisms contributing to the development of vascular cognitive impairment (VCI) associated with CAS are multifaceted and not fully understood. Read More

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Major Complications After Textured Versus Non-textured Breast Implants in Direct-to-Implant Breast Reconstruction: A Propensity Score Analysis.

Aesthetic Plast Surg 2021 Jun 7. Epub 2021 Jun 7.

Division of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY, 10029, USA.

Background: While the risks and benefits of smooth versus textured implants for breast reconstruction and primary breast augmentation are thoroughly supported in the literature, few studies have examined the relationship between implant shell texture and complications following direct-to-implant (DTI) breast reconstruction.

Objectives: The present study examines the relationship between implant shell texture and complications in patients receiving DTI breast reconstruction.

Methods: Retrospective chart review of patients undergoing DTI breast reconstruction between 2011 and 2018 by a single surgeon was performed. Read More

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Permanent IVC filter strut penetration into an abdominal aortic aneurysm.

BMJ Case Rep 2021 Jun 7;14(6). Epub 2021 Jun 7.

Vascular Surgery, Toronto General Hospital, Toronto, Ontario, Canada.

An 85-year-old man with a known history of abdominal aortic aneurysm (AAA) presented to a vascular surgery clinic with a severely swollen, tender and erythematous left leg. An urgent CT angiogram demonstrated a left-sided, proximal deep vein thrombosis, and a permanent, Bird's Nest inferior vena cava (IVC) filter (Cook, Inc., Bloomington, Ind. Read More

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Percutaneous transhepatic treatment of a unique portal vein malformation with portal hypertension in a pediatric patient.

CVIR Endovasc 2021 Jun 7;4(1):47. Epub 2021 Jun 7.

Department of Radiology - Papa Giovanni XXIII Hospital, University of Milano Bicocca, Piazza OMS 1, 24127, Bergamo, Italy.

Background: Anomalies of the portal venous system can be congenital or acquired, the latter being related to spontaneous thrombosis or iatrogenic alterations such as complications of perinatal catheterization of the umbilical vein. These conditions can be clinically silent for years and then manifest abruptly causing severe clinical emergencies.

Case Presentation: This case report describes the diagnosis and interventional management of a singular abnormality in the portal venous system of an 8-year-old female that led to severe portal hypertension and acute variceal bleeding. Read More

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A biography of the point contact fixator (PC-Fix).

S Tepic S Bresina

Eur Cell Mater 2021 Jun 7;41:633-647. Epub 2021 Jun 7.

Scyon Orthopaedics AG, Hardturmstrasse 103, CH-8005, Zurich,

Starting in the mid-eighties, the AO (from the German "Arbeitsgemeinschaft für Osteosynthesefragen") Research Institute (ARI), Davos, Switzerland together with the commercial partners of the AO Foundation embarked on a decade-long project to design, develop, test in experimental animals and human clinical trials as well as bring to clinical use a new system for surgical osteosynthesis. The new plating system, what became known as the Point Contact Fixator (PC-Fix), addressed the shortcomings of the conventional plating by Dynamic Compression Plate (DCP) discovered either by careful examination of the clinical complications or by chance observation and informed inquiry in experimental animals. The focus was on avoiding iatrogenic damage to bone vascularisation caused by the implant design and mechanical function and, thus, aiding efforts of surgeons to preserve vital bone tissue needed for healing. Read More

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Beneficial effects of -fermented black barley on high fat diet-induced fatty liver in rats.

Food Funct 2021 Jun 6. Epub 2021 Jun 6.

Department of Food Science & Technology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.

A long-term high-fat (HF) diet can cause metabolic disorders, which might induce visceral obesity and ectopic triglyceride storage (e.g., hepatic steatosis), and increase hepatic oxidative stress. Read More

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Molecular and Nonmolecular Imaging of Macrophages in Atherosclerosis.

Front Cardiovasc Med 2021 19;8:670639. Epub 2021 May 19.

Department of Cardiology, First Affiliated Hospital of Harbin Medical University, Harbin, China.

Atherosclerosis is a major cause of ischemic heart disease, and the increasing medical burden associated with atherosclerotic cardiovascular disease has become a major public health concern worldwide. Macrophages play an important role in all stages of the dynamic progress of atherosclerosis, from its initiation and lesion expansion increasing the vulnerability of plaques, to the formation of unstable plaques and clinical manifestations. Early imaging can identify patients at risk of coronary atherosclerotic disease and its complications, enabling preventive measures to be initiated. Read More

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Emergent Management of Clostridium difficle Infection in a Patient With Chronic Inflammatory Bowel Disease.

Cureus 2021 Apr 29;13(4):e14751. Epub 2021 Apr 29.

General Surgery, MacDill Air Force Base (AFB), Tampa, USA.

Clostridium difficle (C. diff) is a well known cause of infectious diarrhea across hospitals in the developed world. An anaerobic, gram positive rod bacteria, C. Read More

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Efficacy of Mudan Granule (Combined With Methylcobalamin) on Type 2 Diabetic Peripheral Neuropathy: Study Protocol for a Double-Blind, Randomized, Placebo-Controlled, Parallel-Arm, Multi-Center Trial.

Front Pharmacol 2021 20;12:676503. Epub 2021 May 20.

Department of Endocrinology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

Diabetic peripheral neuropathy (DPN) characterized by nerve damage is a common and disabling chronic microvascular complication in patients with type 2 diabetic mellitus (T2DM), affecting at least half of patients diagnosed with T2DM. Unfortunately, the current treatment for DPN is not ideal. Traditional Chinese medicine (TCM), with a unique theoretical system, has made outstanding contributions in the treatment of T2DM and related complications. Read More

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Complementary use of priors for pulmonary imaging with electrical impedance and ultrasound computed tomography.

J Comput Appl Math 2021 Oct 20;395. Epub 2021 Apr 20.

Department of Mathematics and School of Biomedical Engineering, Colorado State University, CO 80523 USA.

For medical professionals caring for patients undergoing mechanical ventilation due to respiratory failure, the ability to quickly and safely obtain images of pulmonary function at the patient's bedside would be highly desirable. Such images could be used to provide early warnings of developing pulmonary pathologies in real time, thereby reducing the incidence of complications and improving patient outcomes. Electrical impedance tomography (EIT) and low-frequency ultrasound computed tomography (USCT) are two imaging techniques with the potential to provide real-time non-ionizing pulmonary monitoring in the ICU setting, and each method has its own unique advantages as well as drawbacks. Read More

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October 2021

Potentials of MicroRNA in Early Detection of Ovarian Cancer by Analytical Electrical Biosensors.

Crit Rev Anal Chem 2021 Jun 7:1-13. Epub 2021 Jun 7.

Institute of Microengineering and Nanoelectronics, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia.

The importance of nanotechnology in medical applications especially with biomedical sensing devices is undoubted. Several medical diagnostics have been developed by taking the advantage of nanomaterials, especially with electrical biosensors. Biosensors have been predominantly used for the quantification of different clinical biomarkers toward detection, screening, and follow-up the treatment. Read More

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Predictive models of individual risk of elective caesarean section complications: a systematic review.

Eur J Obstet Gynecol Reprod Biol 2021 May 8. Epub 2021 May 8.

University of Aberdeen, Institute of Applied Health Sciences, UK.

Introduction: With increasing caesarean section (c-section) rates, personalized communication of risk has become paramount. A reliable tool to predict complications would support evidence-based discussions around planned mode of birth. This systematic review aimed to identify, synthesize and quality appraise prognostic models of maternal complications of elective c-section. Read More

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Efficacy of Two Unique Combinations of Nerve Blocks on Postoperative Pain and Functional Outcome After Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Study.

J Arthroplasty 2021 May 19. Epub 2021 May 19.

Department of Orthopaedics Surgery, West China Hospital, Sichuan University, Chengdu, People's Republic of China.

Background: This study aimed to explore the efficacy of two unique combinations of nerve blocks on postoperative pain and functional outcome after total knee arthroplasty (TKA).

Methods: Patients scheduled for TKA were randomized to receive a combination of adductor canal block (ACB) + infiltration between the popliteal artery and capsule of the posterior knee block (IPACK) + sham obturator nerve block (ONB) + sham lateral femoral cutaneous nerve block (LFCNB) (control group), or a combination of ACB + IPACK + ONB + sham LFCNB (triple nerve block group), or a combination of ACB + IPACK + ONB + LFCNB (quadruple nerve block group). All patients received local infiltration analgesia. Read More

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Management of chronic Achilles ruptures: a scoping review.

Int Orthop 2021 Jun 5. Epub 2021 Jun 5.

Department of Trauma and Orthopaedic Surgery, University Hospitals Leicester NHS Trust, University Hospitals of Leicester Headquarters, Balmoral Building, Level 3, Leicester, UK.

Purpose: This scoping review aims to systematically map and summarise the available evidence on the management of chronic Achilles ruptures, whilst identifying prognostic factors and areas of future research.

Methods: A scoping review was performed according to the frameworks of Arksey and O'Malley, Levac and Peters. A computer-based search was performed in PubMed, Embase, EmCare, CINAHL, ISI Web of Science and Scopus, for articles reporting treatment of chronic Achilles ruptures. Read More

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Chronic intentional chicken bone ingestion mimicking inflammatory bowel disease.

BMJ Case Rep 2021 Jun 4;14(6). Epub 2021 Jun 4.

Internal Medicine, Naval Medical Center Portsmouth, Portsmouth, Virginia, USA.

Ingestion of food by-products, such as peach pits, chicken bones and fish bones, may lead to intestinal complications. The ingestion of the foreign body is often acute and non-intentional. Acute and life-threatening complications include intestinal perforation or obstruction. Read More

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Intradural Extramedullary Primary Central Nervous System Melanoma of the Craniovertebral Junction during Pregnancy: Observations and Outcomes.

Surg Neurol Int 2021 3;12:198. Epub 2021 May 3.

Department of Surgery, University of Texas Rio Grande Valley, Edinburg, Texas, United States.

Background: Primary central nervous system (CNS) melanoma is a rare lesion derived from neural crest precursors. While its management is analogous to metastatic spinal melanoma, the literature does not describe this entity clearly in pregnant patients and the unique implications it presents. Here, we describe the case of a pregnant patient who presented with primary CNS melanoma of the cervical spine. Read More

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The unique molecular mechanism of diabetic nephropathy: a bioinformatics analysis of over 250 microarray datasets.

Clin Kidney J 2021 Jun 18;14(6):1626-1638. Epub 2021 Mar 18.

Department of Nephrology, Nanjing Medical University Affiliated Wuxi People's Hospital, Wuxi, Jiangsu, China.

Background/aims: Diabetic nephropathy (DN) is one of the main causes of end-stage kidney disease worldwide. Emerging studies have suggested that its pathogenesis is distinct from nondiabetic renal diseases in many aspects. However, it still lacks a comprehensive understanding of the unique molecular mechanism of DN. Read More

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MMP12 is a potential therapeutic target for Adamantinomatous craniopharyngioma: Conclusions from bioinformatics analysis and experiments.

Oncol Lett 2021 Jul 19;22(1):536. Epub 2021 May 19.

Department of Neurosurgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.

Adamantinomatous craniopharyngioma (ACP) is considered a benign intracranial tumor, but it can also exhibit aggressive characteristics. Due to its unique location in the suprasellar, which brings it close to important nerves and vascular structures, ACP can often lead to significant neuroendocrine diseases. The current treatments primarily include surgical intervention, radiation therapy or a combination of the two, but these can lead to serious complications and adversely affect the quality of life of patients. Read More

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Bilateral gemination of permanent maxillary canine with labial and palatal talon's cusps: A rare entity.

J Oral Maxillofac Pathol 2021 Mar 19;25(Suppl 1):S71-S75. Epub 2021 Mar 19.

Department of Oral Pathology and Microbiology, Dental College, Regional Institute of Medical Sciences, Imphal, Manipur, India.

Gemination is a morphologic anomaly of the tooth characterized by the formation of a macrodont. Bilateral presentation is rarely reported in permanent canines. Talon's cusp is an accessory cusp projecting lingually from the cingulum to the incisal edge and may be seen facially sometimes. Read More

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Comparable outcomes after alternative and matched sibling donor hematopoietic stem cell transplantation and the role of molecular measurable residual disease for acute myeloid leukemia in elderly patients.

Transplant Cell Ther 2021 May 31. Epub 2021 May 31.

Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Leukemia Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address:

Background: Allogeneic hematopoietic stem cell transplantation (HSCT) remains the most effective post-remission therapy conferring the chance of cure for acute myeloid leukemia (AML), including elderly patients. Although the number of transplants for elderly patients with AML (eAML) is increasing owing to greater availability of various graft sources together with the adoption of advanced supportive care and reduced-intensity conditioning (RIC) regimen, there are relatively limited data on the impact of donor type in eAML compared to younger patients. In addition, few studies have evaluated the role of pre-transplant measurable residual disease (MRD) in elderly population. Read More

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Decision models in type 2 diabetes mellitus: A systematic review.

Acta Diabetol 2021 Jun 3. Epub 2021 Jun 3.

Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, 730000, Gansu Province, China.

Aims: To reduce the burden of type 2 diabetes (T2DM), the disease decision model plays a vital role in supporting decision-making. Currently, there is no comprehensive summary and assessment of the existing decision models for T2DM. The objective of this review is to provide an overview of the characteristics and capabilities of published decision models for T2DM. Read More

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