Comput Biol Med 2021 04 22;131:104264. Epub 2021 Feb 22.
Department of Mathematics, Michigan State University, MI, 48824, USA; Department of Electrical and Computer Engineering, Michigan State University, MI, 48824, USA; Department of Biochemistry and Molecular Biology, Michigan State University, MI, 48824, USA. Electronic address:
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a worldwide devastating effect. Understanding the evolution and transmission of SARS-CoV-2 is of paramount importance for controlling, combating and preventing COVID-19. Due to the rapid growth in both the number of SARS-CoV-2 genome sequences and the number of unique mutations, the phylogenetic analysis of SARS-CoV-2 genome isolates faces an emergent large-data challenge. Read More