Exp Neurol 2021 May 2:113735. Epub 2021 May 2.
Department of Physical Therapy, University of Florida, Gainesville, FL, United States; Brooks Rehabilitation, Jacksonville, FL, United States; Breathing Research and Therapeutics Center, University of Florida, Gainesville, FL, United States. Electronic address:
After spinal cord injury (SCI) respiratory complications are a leading cause of morbidity and mortality. Acute intermittent hypoxia (AIH) triggers spinal respiratory motor plasticity in rodent models, and repetitive AIH may have the potential to restore breathing capacity in those with SCI. As an initial approach to provide proof of principle for such effects, we tested single-session AIH effects on breathing function in adults with chronic SCI. Read More