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Improving long-term outcomes in pediatric torcular dural sinus malformations with embolization and anticoagulation: a retrospective review of The Hospital for Sick Children experience.

J Neurosurg Pediatr 2021 Jul 30:1-7. Epub 2021 Jul 30.

1Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto.

Objective: Torcular dural sinus malformations (tDSMs) are rare pediatric cerebrovascular malformations characterized by giant venous lakes localized to the midline confluence of sinuses. Historical clinical outcomes of patients with these lesions were poor, though better prognoses have been reported in the more recent literature. Long-term outcomes in children with tDSMs are uncertain and require further characterization. Read More

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Distinct approaches to language pathway tractography: comparison of anatomy-based, repetitive navigated transcranial magnetic stimulation (rTMS)-based, and rTMS-enhanced diffusion tensor imaging-fiber tracking.

J Neurosurg 2021 Jul 30:1-12. Epub 2021 Jul 30.

Departments of1Neurosurgery and.

Objective: Visualization of subcortical language pathways by means of diffusion tensor imaging-fiber tracking (DTI-FT) is evolving as an important tool for surgical planning and decision making in patients with language-suspect brain tumors. Repetitive navigated transcranial magnetic stimulation (rTMS) cortical language mapping noninvasively provides additional functional information. Efforts to incorporate rTMS data into DTI-FT are promising, but the lack of established protocols makes it hard to assess clinical utility. Read More

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Effect of the ultrasonic standing wave frequency on the attractive mineralization for fine coal particle flotation.

Ultrason Sonochem 2021 Jul 23;77:105682. Epub 2021 Jul 23.

School of Chemical Engineering and Technology, China University of Mining and Technology, Xuzhou 221116, Jiangsu, China.

Froth flotation for mineral beneficiation is one of the most important separation techniques; however, it has several challenges for processing fine and ultrafine particles. Attractive mineralization between particles and bubbles by ultrasonic standing wave (USW) is a novel and high-efficiency method that could assist fine particle flotation. Frequency is an important ultrasound parameter, whose effectiveness mechanisms on the attractive mineralization did not compressively address. Read More

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Characterization of the structural and dynamic changes of cell wall obtained by ultrasound-water and ultrasound-alkali treatments.

Ultrason Sonochem 2021 Jul 18;77:105672. Epub 2021 Jul 18.

Beijing Key Laboratory of Wood Science and Engineering, College of Material Science and Technology, Beijing Forestry University, No. 35 Tsinghua East Road Haidian District, Beijing, PR China. Electronic address:

It is well-known that ultrasound has been studied for its cavitation, mechanical and thermal effects. As a pretreatment technology, ultrasonic alkali treatment has attracted much attention in the field of biomass biochemical transformation. In this study, the structural and dynamic changes of wood cell walls during ultrasound-water, alkali, and ultrasound-alkali treatments were investigated by stereoscopic microscopy, confocal Raman microscopy, Fourier-transform infrared spectroscopy, and X-ray diffraction. Read More

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Primary synovial sarcoma of thyroid gland: A case report and review of literature.

Int J Surg Case Rep 2021 Jul 26;85:106245. Epub 2021 Jul 26.

Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Introduction And Importance: Synovial cell sarcoma (SS) is an extremely rare mesenchymal malignancy, representing nearly 10% of all soft-tissue sarcomas. These high-grade soft tissue sarcomas commonly arise in the para-articular regions of lower extremities. However, 15% of Synovial sarcomas has been described at Unusual locations, including head, neck, and trunk. Read More

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Placental lesions and SARS-Cov-2 infection: Diffuse placenta damage associated to poor fetal outcome.

Placenta 2021 Jul 15;112:97-104. Epub 2021 Jul 15.

Institut de Pathologie Multisite des Hospices Civils de Lyon, 69677, Bron Cedex, Lyon, France; SOFFOET-Société Française de Fœtopathologie, 75014, Paris, France; Université Claude Bernard Lyon 1, Faculté de Médecine Lyon Est, 69008, France.

Introduction: Pregnant women with covid-19 are more likely to experience preterm birth. The virus seems to be associated with a wide range of placental lesions, none of them specific.

Method: We collected cases of Covid-19 maternal infection during pregnancy associated with poor pregnancy outcomes, for which we received the placenta. Read More

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Multiscale and multimodal imaging of utero-placental anatomy and function in pregnancy.

Placenta 2021 Jul 23;112:111-122. Epub 2021 Jul 23.

Auckland Bioengineering Institute, University of Auckland, New Zealand.

Placental structures at the nano-, micro-, and macro scale each play important roles in contributing to its function. As such, quantifying the dynamic way in which placental structure evolves during pregnancy is critical to both clinical diagnosis of pregnancy disorders, and mechanistic understanding of their pathophysiology. Imaging the placenta, both exvivo and invivo, can provide a wealth of structural and/or functional information. Read More

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An in silico validation framework for quantitative DCE-MRI techniques based on a dynamic digital phantom.

Med Image Anal 2021 Jul 20;73:102186. Epub 2021 Jul 20.

Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, 201 E 24th St, Austin, TX 78712, United States; Livestrong Cancer Institutes, United States; Departments of Biomedical Engineering, United States; Departments of Diagnostic Medicine, United States; Departments of Oncology, The University of Texas at Austin, Austin, TX 78712, United States; Department of Imaging Physics, MD Anderson Cancer Center, Houston, TX 77030, United States.

Quantitative evaluation of an image processing method to perform as designed is central to both its utility and its ability to guide the data acquisition process. Unfortunately, these tasks can be quite challenging due to the difficulty of experimentally obtaining the "ground truth" data to which the output of a given processing method must be compared. One way to address this issue is via "digital phantoms", which are numerical models that provide known biophysical properties of a particular object of interest. Read More

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Idiopathic pyometra in a postmenopausal patient.

Clin Imaging 2021 Jul 26;80:145-147. Epub 2021 Jul 26.

Department of Radiology, St. Joseph Mercy Oakland Hospital, Pontiac, MI, United States; Huron Valley Radiology, Ypsilanti, MI, United States.

Pyometra is a rare gynecological condition most commonly seen in elderly, postmenopausal women. Malignancy should always be considered as the primary etiology until proven otherwise in the investigation of an intrauterine infection. Clinical signs and symptoms can be vague or nonexistent, and thorough investigation with ultrasound and cross-sectional imaging may be necessary to understand the extent of the disease and best course of treatment. Read More

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Carpal tunnel syndrome treatment and the subsequent alterations in tendon and connective tissue dynamics.

Clin Biomech (Bristol, Avon) 2021 Jul 24;88:105440. Epub 2021 Jul 24.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, United States. Electronic address:

Background: Carpal tunnel syndrome patients demonstrate diminished motion of the median nerve and fibrotic changes in the subsynovial connective tissue within the carpal tunnel. Currently, there are few prognostic factors to help predict the outcome of commonly performed treatments including surgical carpal tunnel release and corticosteroid injections. This study aimed to non-invasively assess the changes in the dynamic response of the subsynovial tissue relative to tendon motion after the intervention and to correlate this with disease severity. Read More

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Clinical and service delivery implications of omitting ultrasound before medication abortion provided via direct-to-patient telemedicine and mail.

Contraception 2021 Jul 27. Epub 2021 Jul 27.

Gynuity Health Projects, 220 East 42nd Street #710, New York, NY 10017. Electronic address:

Objectives: To compare outcomes among patients who did or did not have pre-abortion ultrasound or pelvic exam before obtaining medication abortion (MA) via direct-to-patient telemedicine and mail.

Study Design: We analyzed data from participants screened for enrollment into the TelAbortion study at five sites from March 25-September 15, 2020. We compared participants who had pre-abortion ultrasound or pelvic exam ("test-MA") to those who did not ("no-test MA"). Read More

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The chest radiographic scoring system in initial diagnosis of COVID-19: Is a radiologist needed?

Adv Clin Exp Med 2021 Jul 30. Epub 2021 Jul 30.

Department of General Radiology, Interventional Radiology and Neuroradiology, Wroclaw Medical University, Poland.

Background: Lung imaging, next to a polymerase chain reaction (PCR) test, is a key diagnostic tool in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The degree of abnormalities correlates with clinical outcome. Imaging of the lungs using chest radiography (CXR) at the peak of a pandemic is considered a basic diagnostic tool at the triage stage. Read More

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From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns.

Hum Reprod Update 2021 Jul 30. Epub 2021 Jul 30.

Competence Centre on Health Technologies, Tartu, Estonia.

Background: With the help of ART, an advanced parental age is not considered to be a serious obstacle for reproduction anymore. However, significant health risks for future offspring hide behind the success of reproductive medicine for the treatment of reduced fertility associated with late parenthood. Although an advanced maternal age is a well-known risk factor for poor reproductive outcomes, understanding the impact of an advanced paternal age on offspring is yet to be elucidated. Read More

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Analytical Comparison of Pregnancy-Associated Plasma Protein-A (PAPP-A) Immunoassays for Biochemical Determination of Gestational Age.

J Appl Lab Med 2021 Jul 30. Epub 2021 Jul 30.

Gynuity Health Projects, New York, NY 10017.

Background: Accurate pregnancy dating is critical for maternal and child health and for counseling on safe and effective abortion methods. While last menstrual period and first trimester ultrasound are often used together to determine gestational age (GA), they have limited accuracy and availability, respectively. Prior studies have shown that pregnancy-associated plasma protein-A (PAPP-A) increases exponentially during pregnancy and has the potential to serve as a biochemical marker of GA. Read More

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Deep learning with robustness to missing data: A novel approach to the detection of COVID-19.

PLoS One 2021 30;16(7):e0255301. Epub 2021 Jul 30.

Diagnostic Image Analysis Group, Radboudumc, Nijmegen, The Netherlands.

In the context of the current global pandemic and the limitations of the RT-PCR test, we propose a novel deep learning architecture, DFCN (Denoising Fully Connected Network). Since medical facilities around the world differ enormously in what laboratory tests or chest imaging may be available, DFCN is designed to be robust to missing input data. An ablation study extensively evaluates the performance benefits of the DFCN as well as its robustness to missing inputs. Read More

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Multiparametric Quantitative US Examination of Liver Fibrosis: A Feature-engineering and Machine-learning Based Analysis.

IEEE J Biomed Health Inform 2021 Jul 30;PP. Epub 2021 Jul 30.

Quantitative ultrasound (QUS), which is commonly used to extract quantitative features from the ultrasound radiofrequency (RF) data or the RF envelope signals for tissue characterization, is becoming a promising technique for noninvasive assessments of liver fibrosis. However, the number of feature variables examined and finally used in the existing QUS methods is typically small, to some extent limiting the diagnostic performance. Therefore, this paper devises a new multiparametric QUS (MP-QUS) method which enables the extraction of a large number of feature variables from US RF signals and allows for the use of feature-engineering and machinelearning based algorithms for liver fibrosis assessment. Read More

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Subharmonic Scattering of SonoVueTM Microbubbles within 10-40 mmHg Overpressures in Vitro.

IEEE Trans Ultrason Ferroelectr Freq Control 2021 Jul 30;PP. Epub 2021 Jul 30.

Ultrasound contrast agent microbubbles are considered promising sensors to measure portal vein pressure noninvasively. In this study, we investigated the subharmonic scattering power and optimal incident acoustic pressure of SonoVueTM microbubbles (concentration: 1μL/mL 0.9% NaCl solution) in the ambient pressure range of 10-40 mmHg with 10 mmHg increments at a temperature of 25 °C. Read More

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Quantitative Biomarkers for Cancer Detection Using Contrast-Free Ultrasound High-Definition Microvessel Imaging: Fractal Dimension, Murray's Deviation, Bifurcation Angle & Spatial Vascularity Pattern.

IEEE Trans Med Imaging 2021 Jul 30;PP. Epub 2021 Jul 30.

A growing body of evidence indicates that there is a strong correlation between microvascular morphological features and malignant tumors. Therefore, quantification of these features might allow more accurate differentiation of benign and malignant tumors. The main objective of this research project is to improve the quantification of microvascular networks depicted in contrast-free ultrasound microvessel images. Read More

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Deep Interactive Denoiser (DID) for X-Ray Computed Tomography.

IEEE Trans Med Imaging 2021 Jul 30;PP. Epub 2021 Jul 30.

Low-dose computed tomography (LDCT) is desirable for both diagnostic imaging and image-guided interventions. Denoisers are widely used to improve the quality of LDCT. Deep learning (DL)-based denoisers have shown state-of-the-art performance and are becoming mainstream methods. Read More

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A Flexible Cystoscope Based on Hydrodynamic Cavitation for Tumor Tissue Ablation.

IEEE Trans Biomed Eng 2021 Jul 30;PP. Epub 2021 Jul 30.

Hydrodynamic cavitation involves the formation of bubbles inside a flow due to local reduction of pressure below the saturation vapor pressure. The resulting growth and violent collapse of bubbles lead to a huge amount of released energy. This energy can be implemented in different fields such as heat transfer enhancement, wastewater treatment and chemical reactions. Read More

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Synthesis of magnetic tungsten disulfide/carbon nanotubes nanocomposite (WS/FeO/CNTs-NC) for highly efficient ultrasound-assisted rapid removal of amaranth and brilliant blue FCF hazardous dyes.

J Hazard Mater 2021 Jul 14;420:126644. Epub 2021 Jul 14.

Department of Chemistry, Faculty of Sciences, University of Sistan of Baluchestan, Zahedan, Iran.

In this research, the potentiality of magnetic tungsten disulfide/carbon nanotubes nanocomposite (WS/FeO/CNTs-NC) as an adsorbent for the ultrasound-assisted removal of amaranth (AM) and brilliant blue FCF (BB FCF) dyes was investigated. The experiments were conducted using a central composite design (CCD) with the inputs of solution pH (X: 2.0-10), adsorbent mass (X: 4-20 mg), AM concentration (X: 10-50 mg L), BB FCF concentration (X: 10-50 mg L), and sonication time (X: 2-12 min). Read More

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Simultaneous removal of colonial Microcystis and microcystins by protozoa grazing coupled with ultrasound treatment.

J Hazard Mater 2021 Jul 9;420:126616. Epub 2021 Jul 9.

Jiangsu Province Key Laboratory for Biodiversity and Biotechnology, School of Biological Sciences, Nanjing Normal University, 1 Wenyuan Road, Nanjing 210023, China. Electronic address:

Removal of harmful cyanobacteria is an extremely urgent task in global lake management and protection. Conventional measures are insufficient for simultaneously removing cyanobacteria and hazardous cyanotoxin, efficient and environmental-friendly measures are therefore particularly needed. Herbivorous protozoa have great potentials in controlling algae, however, large-sized colonial Microcystis is inedible for protozoa, which is a central problem to be solved. Read More

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The superior adsorption capacity of 2,4-Dinitrophenol under ultrasound-assisted magnetic adsorption system: Modeling and process optimization by central composite design.

J Hazard Mater 2021 Jun 8;418:126348. Epub 2021 Jun 8.

Department of Environmental Health Engineering, School of Public Health, Hamadan University of Medical Science, Hamadan, Iran.

2,4-Dinitrophenol (DNP) was listed as a priority pollutant; accordingly, DNP-contaminated effluent must be treated before discharging to the receiving resources. In the present study, the hybrid ultrasound-assisted GO-FeO system was employed to decontaminate DNP solution. Ultrasound irradiation makes the mass transfer of adsorbate improved and FeO enables GO separation from liquid phase under external magnetic field. Read More

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Role of driven approach on the piezoelectric ozonation processes: Comparing ultrasound with hydro-energy as driving forces.

J Hazard Mater 2021 Jun 11;418:126392. Epub 2021 Jun 11.

State Key Laboratory of Coal Mine Disaster Dynamics and Control, Chongqing University, Chongqing 400044, PR China; Key Laboratory of the Three Gorges Reservoir Region's Eco-Environment, Ministry of Education, Chongqing University, Chongqing 400045, PR China. Electronic address:

Driven approach is vital for evaluating degradation and energy efficiencies of piezocatalysis process. Thus, piezoelectric ozonation processes driven by hydraulic (HPE-O) and ultrasonic (UPE-O) forces were compared systematically, using BaTiO as piezoelectric material for ibuprofen (IBP) degradation. The synergy indexes of HPE-O and UPE-O processes were 4. Read More

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Aortic Fistulas: Pathophysiologic Features, Imaging Findings, and Diagnostic Pitfalls.

Radiographics 2021 Jul 30:210004. Epub 2021 Jul 30.

From the Department of Radiology, Thomas Jefferson University Hospital, 132 S 10th St, Philadelphia, PA 19107 (A.G., A.D., M.P.); Department of Radiology, University of Kentucky Medical Center, Lexington, Ky (H.K.); and Division of Interventional Radiology, Tata Memorial Hospital, Homi Bhabha University, Mumbai, India (K.G.).

Fistulas between the aorta and surrounding organs are extremely rare but can be fatal if they are not identified and treated promptly. Most of these fistulas are associated with a history of trauma or vascular intervention. However, spontaneous aortic fistulas (AoFs) can develop in patients with weakened vasculature, which can be due to advanced atherosclerotic disease, collagen-vascular disease, vasculitides, and/or hematogenous infections. Read More

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Neoadjuvant Intraperitoneal and Systemic Chemotherapy Versus Neoadjuvant Systemic Chemotherapy With Docetaxel, Oxaliplatin, and S-1 for Gastric Cancer With Peritoneal Metastasis: A Propensity Score Matched Analysis.

Technol Cancer Res Treat 2021 Jan-Dec;20:15330338211036310

Department of Gastrointestinal Surgery, 56652Changzheng Hospital, Naval Medical University, Shanghai, China.

Background: The optimal treatment for gastric cancer with peritoneal metastasis (GCPM) remains debatable. This study aimed to compare the efficacy and safety of neoadjuvant intraperitoneal and systemic chemotherapy (NIPS) versus neoadjuvant systemic chemotherapy (NSC) for GCPM.

Methods: Patients of GCPM received neoadjuvant chemotherapy with docetaxel, oxaliplatin and S-1 between January 2011 and June 2019 were retrospectively evaluated. Read More

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A Role for Ultrasonography in the Diagnostic Evaluation of Lymphedema.

Authors:
S G Rockson

Lymphat Res Biol 2021 Aug;19(4):321

Stanford University School of Medicine.

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Integration of chemically modified nucleotides with DNA strand displacement reactions for applications in living systems.

Wiley Interdiscip Rev Nanomed Nanobiotechnol 2021 Jul 30:e1743. Epub 2021 Jul 30.

Department of Chemistry, Texas A&M University, College Station, Texas, USA.

Watson-Crick base pairing rules provide a powerful approach for engineering DNA-based nanodevices with programmable and predictable behaviors. In particular, DNA strand displacement reactions have enabled the development of an impressive repertoire of molecular devices with complex functionalities. By relying on DNA to function, dynamic strand displacement devices represent powerful tools for the interrogation and manipulation of biological systems. Read More

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The MUSICAL pediatric ultrasound examination - a comprehensive, reliable, time efficient assessment of synovitis.

Arthritis Care Res (Hoboken) 2021 Jul 30. Epub 2021 Jul 30.

Hebrew SeniorLife, IFAR, 1200 Centre St, Boston, Massachusetts, USA.

Objective: To develop and initially validate a comprehensive pediatric musculoskeletal ultrasound (MSUS) joint-specific scoring system. To determine the minimum number of joints needed to identify active disease.

Methods: A semiquantitative scoring system was developed by consensus and initially validated by inter-rater reliability using intraclass correlation coefficients (ICC). Read More

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Radiologic Imaging Modalities for Colorectal Cancer.

Dig Dis Sci 2021 Jul 30. Epub 2021 Jul 30.

Department of Radiology, Jinshan Hospital, Fudan University, 1508 Longhang Rd., Jinshan District, Shanghai, 201508, China.

Background: Studies reported various diagnostic value of radiologic imaging modalities for diagnosis and management of colorectal cancer (CRC).

Aims: To summary the diagnosis and management of CRC using computed tomography colonography (CTC), magnetic resonance colonography (MRC), and positron emission tomography (PET)/computed tomography (CT).

Methods: Comprehensive literature searches were conducted in PubMed, EmBase, and the Cochrane library for studies published before April 2021. Read More

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