36 results match your criteria ulcerative paronychia

The role of topical timolol in wound healing and the treatment of vascular lesions: A narrative review.

Dermatol Ther 2021 Mar 13;34(2):e14847. Epub 2021 Feb 13.

Department of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Beta-2 adrenergic receptors are the only subgroup of beta-adrenergic receptors expressed in the membrane of large cells, including skin keratinocytes, fibroblasts, and melanocytes. Alterations in the function or concentration of β2 adrenoreceptors related to keratinocytes are associated with some skin conditions. Some findings suggest the role of β2 adrenoreceptors in maintaining the function and integrity of the epidermis. Read More

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Atypical and unusual morphological variants of cutaneous leishmaniasis.

Int J Clin Pract 2020 Oct 26:e13730. Epub 2020 Oct 26.

Department of Pathology, Harran University Medical Faculty, Sanliurfa, Turkey.

Objective: Cutaneous leishmaniasis (CL) is a skin disease characterised by prolonged nodulo-ulcerative lesions of the skin that heals with atrophic scar. Clinical features of CL vary depending on the type of parasite and host immune resistance. The aim of this study was to investigate the clinical features of atypical and unusual morphological variants of CL patients diagnosed in our clinic. Read More

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October 2020

Low-Dose Erlotinib Treatment in Elderly or Frail Patients With EGFR Mutation-Positive Non-Small Cell Lung Cancer: A Multicenter Phase 2 Trial.

JAMA Oncol 2020 07 9;6(7):e201250. Epub 2020 Jul 9.

Department of Respiratory Medicine and Medical Oncology, Yokohama Municipal Citizen's Hospital, Yokohama, Japan.

Importance: Although the efficacy of epidermal growth factor receptor tyrosine kinase inhibitors for EGFR gene mutation-positive non-small cell lung cancer is well established, optimal dosing remains to be established, especially in elderly or frail patients.

Objective: To investigate the efficacy and safety of low-dose erlotinib in elderly or frail patients with EGFR mutation-positive non-small cell lung cancer.

Design, Setting, And Participants: Single-arm phase 2 trial with the Southwest Oncology Group (SWOG) 2-stage design that enrolled frail patients from 21 Japanese institutions after meeting the inclusion criteria. Read More

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Skin Infections and Outpatient Burn Management: Skin Infections in Patients With Diabetes.

Maulik M Dhandha

FP Essent 2020 Feb;489:21-26

Maine-Dartmouth Family Medicine Residency, 15 East Chestnut St, Augusta, ME 04330.

Diabetes is associated with many complications, including foot ulcers. Individuals with diabetes have a 15% to 25% likelihood of developing a foot ulcer in their lifetime. The pathophysiologic mechanisms are multifactorial but the major etiologic factors are peripheral vascular disease and diabetic neuropathy. Read More

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February 2020

Non-healing ulcerative paronychia.

Lancet 2017 04 23;389(10080):1740. Epub 2016 Dec 23.

Division of Dermatology, McGill University, Montreal, Quebec, Canada.

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Non healing legs ulcers infected with Stenotrophomonas maltophilia.

Ann Ital Chir 2013 Apr 12;84(ePub). Epub 2013 Apr 12.

Department of Plastic, Reconstructive and Aesthetic Surgery, University of Rome Sapienza, Policlinico Umberto I, 00141 Rome, Italy.

Stenotrophomonas maltophilia (S.M.) is a Gram-negative bacillus, naturally resistant to cephalosporins and carbapenems, which can colonize different sites and may be responsible for serious infections for which treatment is a real challenge. Read More

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[The acrolentiginous melanoma: how to recognise and when to refer?].

Ned Tijdschr Geneeskd 2012 ;156(34):A4927

Maastricht Universitair Medisch Centrum, afd. Dermatologie, Maastricht, the Netherlands.

In Caucasians, the acrolentiginous melanoma is a rare type of melanoma and may appear on hands, feet and subungually. It has the worst prognosis of all melanomas, due to the high rate of misdiagnosis. In 30% of the patients, it presents amelanotic and may resemble for example a common wart, paronychia, ulceration or mycosis. Read More

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A rare case of diabetic hand ulcer caused by Streptococcus agalactiae.

Int J Low Extrem Wounds 2012 Sep 2;11(3):174-6. Epub 2012 Aug 2.

Shanghai Jiao Tong University, Shanghai, Peoples' Republic of China.

This study reports the case of a 71-year-old woman with type 2 diabetes whose paronychia rapidly progressed to the right middle finger and then to the whole dorsal aspect necrosis of the right hand. After admission, the diagnosis of diabetic hand ulcer was established and Streptococcus agalactiae found as the pathogen. The authors controlled glucose, used 3% hydrogen peroxide and sulfadiazine silver in routine dressing, as well as surgical debridement, topical negative pressure, and skin grafting. Read More

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September 2012

An unusual presentation of juvenile systemic lupus erythematosus.

Clin Exp Dermatol 2012 Apr;37(3):249-51

Department of Dermatology, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.

Systemic lupus erythematosus (SLE) is a multisystem disorder with a diverse spectrum of clinical abnormality. Despite advances in our understanding of the disease, the aetiology and outcome remains unknown. We describe a 13-year-old boy who presented with paronychia, mouth ulcers and associated neutropenia. Read More

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Non healing leg ulcer infected with Stenotrophomonas maltophilia: first reported case from India.

Int Wound J 2013 Jun 31;10(3):356-8. Epub 2012 Jan 31.

Department of Dermatology, IPGMER & SSKM Hospital, Kolkata, India.

Stenotrophomonas maltophilia is a recently described organism which was mainly reported either in nosocomial setup, or in immunosuppresed individuals. This was rarely reported as cutaneous pathogenic organism causing cellulitis-like lesion, paronychia, mucocutaneous ulcers and ecthyma gangrenosum in immunocompromised individuals. Here we describe a case of leg ulcer caused by S. Read More

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A classification of diabetic foot infections using ICD-9-CM codes: application to a large computerized medical database.

BMC Health Serv Res 2010 Jul 6;10:192. Epub 2010 Jul 6.

Center for Health Quality Outcomes and Economic Research, Bedford VA Medical Center, 200 Springs Road, Bedford, MA 01730, USA.

Background: Diabetic foot infections are common, serious, and varied. Diagnostic and treatment strategies are correspondingly diverse. It is unclear how patients are managed in actual practice and how outcomes might be improved. Read More

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Herpes Simplex Virus Type 1 infection: overview on relevant clinico-pathological features.

J Oral Pathol Med 2008 Feb;37(2):107-21

Department of Biomedical Sciences and Human Oncology, Oral Medicine Section, University of Turin, Turin, Italy.

Herpes Simplex Virus Type 1 (HSV-1) is a nuclear replicating enveloped virus, usually acquired through direct contact with infected lesions or body fluids (typically saliva). The prevalence of HSV-1 infection increases progressively from childhood, the seroprevalence being inversely related to socioeconomic background. Primary HSV-1 infections in children are either asymptomatic or following an incubation period of about 1 week gives rise to mucocutaneous vesicular eruptions. Read More

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February 2008

[Chancre of the finger. A circuitous route to diagnosis].

Hautarzt 2008 Jun;59(6):499-502

Klinik für Dermatologie, Allergologie und Venerologie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.

A 33-year-old woman presented with a 4-months history of a granulating ulcer on the right index finger. Paronychia was suspected and nail extraction with subsequent histopathologic examination of the removed tissue was performed. Two months later, it became known that the patient's sexual partner had been treated for syphilis. Read More

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Antimicrobial resistance of Staphylococcus aureus isolated from impetigo patients between 1994 and 2000.

Int J Dermatol 2003 Jan;42(1):23-5

Department of Dermatology and Bacterial Medicine Laboratories, Kansa Medical University, Kori Hospital, Neyagawa, Osaka, Japan.

Background: The incidence of strains of Staphylococcus aureus resistant to the antimicrobial agents used in treating impetigo has been increasing.

Aim: To determine the antimicrobial susceptibility of S. aureus in impetigo. Read More

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January 2003

Subungual squamous cell carcinoma: report of 2 cases.

J Formos Med Assoc 2000 Aug;99(8):646-9

Department of Orthopedic Surgery, Cardinal Tien Hospital, Taipei, Taiwan.

Subungual squamous cell carcinoma (SCC) is a rare malignant tumor with an indolent course. Its etiology is unknown. It often involves the distal phalanx of the thumb or the index finger, and often presents as a chronic ulcer that is commonly misdiagnosed as chronic paronychia, pyogenic granuloma or verruca vulgaris. Read More

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An unusual case of pemphigus vulgaris presenting as bilateral foot ulcers.

H H Tan Y K Tay

Clin Exp Dermatol 2000 May;25(3):224-6

National Skin Centre, Singapore.

We describe an unusual presentation of pemphigus vulgaris, an autoimmune intraepidermal blistering skin disease associated with autoantibodies to the desmosome glycoprotein, desmoglein 3. A 60-year-old man presented with bilateral ulceration on the dorsum of the feet. These clinical features persisted for 4 months before more characteristic signs of pemphigus vulgaris, including mouth ulceration and skin erosions, developed. Read More

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Diseases of the foot and nails: humans, cats, and dogs.

Clin Dermatol 1994 Oct-Dec;12(4):573-7

Apple Valley Veterinarians, Plantsville, Connecticut 06030.

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Intravenous iloprost treatment of Raynaud's phenomenon and ischemic ulcers secondary to systemic sclerosis.

J Rheumatol 1992 Sep;19(9):1407-14

Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ.

Objective: We conducted this study to assess the clinical usefulness and physiologic effects of intravenous iloprost in patients with Raynaud's phenomenon secondary to systemic sclerosis.

Methods: Thirty-five patients with Raynaud's phenomenon secondary to systemic sclerosis, including 11 with digital ischemic ulcerations, were enrolled in a double blind placebo controlled parallel study in 2 centers. Following a 2 week washout, subjects received intravenous iloprost (0. Read More

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September 1992

Fixed-drug eruption presenting as an acute paronychia.

R Baran C Perrin

Br J Dermatol 1991 Dec;125(6):592-5

Department of Dermatology, Cannes General Hospital, France.

A case of fixed-drug eruption due to cefalexine presented with acute paronychia. Twenty days after a further challenge with a single dose of the drug, a biopsy of the affected skin showed intense expression for ICAM-1. Read More

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December 1991

Unusual presentation of Pseudomonas aeruginosa infections: a review.

Bol Asoc Med P R 1991 Apr;83(4):160-3

Infections Disease Program, University of Puerto Rico School of Medicine, San Juan Department of Veterans Affairs 00927-5800.

Pseudomonas aeruginosa is an opportunistic, gram negative bacillus that causes serious hospital acquired infections. However, it also causes infections with unusual presentations which are acquired in a non-hospital environment. This report will discuss the pathogenesis, clinical manifestations, and therapy of this uncommon infection, such as: 1) Pseudomonas folliculitis: a superficial or deep bacterial infection associated with the use of public hot tubs, whirlpools and swimming pools. Read More

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The influence of external precipitating factors and peripheral neuropathy on the development and outcome of diabetic foot ulcers.

J Diabet Complications 1990 Jan-Mar;4(1):21-5

Department of Internal Medicine, University Hospital, Lund, Sweden.

The influence of external precipitating factors and the presence of peripheral neuropathy on the development and outcome of foot ulcers were evaluated in 314 consecutive diabetic patients. All patients were treated by the same foot care team. Each patient was represented by one ulcer, and primary healing was defined as intact skin for at least six months. Read More

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[Zinc deficiency in artificial nutrition].

F Nürnberger

Z Hautkr 1987 ;62 Suppl 1:104-10

Hautklinik und Poliklinik, Freien Universität, Berlin Universitätsklinikum Rudolf Virchow.

A 35-year-old patient was parenterally fed for a total of 170 days because of a twice reoperated gastric ulcer followed by a gastric-antrum small intestinal fistula. This lead to a complete acute zinc deficiency syndrome with pronounced acrodermatitis enteropathica-like skin changes in the face and the genital region, paronychia, flat blistering on the hands and feet, loss of hair, fingernail ridging (Beau's) and serious physical changes. A dramatic improvement and healing of all these skin changes, the antrum and small intestinal fistula as well as physical disorders occurred after intravenous and subsequent oral intake of zinc. Read More

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Cutaneous stigmata frequently found in the diabetic limb.

M A Brenner

Clin Podiatr Med Surg 1986 Jul;3(3):523-32

Dr. Brenner provides us with a look at some of the common skin problems seen in patients who have diabetes mellitus. As he points out, several of these skin conditions precede the actual clinical and laboratory diagnosis of diabetes by several months to several years. Read More

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[Bowen disease of the nail apparatus. Report of 5 cases and review of the 20 cases of the literature (author's transl)].

Ann Dermatol Venereol 1979 Mar;106(3):227-33

Five cases of Bowen disease of the nail apparatus were studied and the 20 cases published to date reviewed. The lesion was characterized by either periungual redness with scaling and erosions, whitish cuticle, hyperkeratotic or papilomatous process, fissure or crusted ulcer in the lateral nail fold or the nail bed with eventual partial or total destruction of the nail plate and sometimes soreness on the pressure. The key of the diagnosis is the histological picture, identical with that of Bowen diseases of other skin areas. Read More

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Livedo with ulceration.

B R Jones

Br J Dermatol 1973 Feb;88(2):202-4

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February 1973