134,324 results match your criteria type iii


TAFA4 relieves injury-induced mechanical hypersensitivity through LDL receptors and modulation of spinal A-type K current.

Cell Rep 2021 Oct;37(4):109884

Aix-Marseille Université, CNRS, Institut de Biologie du Développement de Marseille, UMR 7288, Case 907, 13288 Marseille Cedex 09, France. Electronic address:

Pain, whether acute or persistent, is a serious medical problem worldwide. However, its management remains unsatisfactory, and new analgesic molecules are required. We show here that TAFA4 reverses inflammatory, postoperative, and spared nerve injury (SNI)-induced mechanical hypersensitivity in male and female mice. Read More

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October 2021

Functional response and preference of Diachasmimorpha longicaudata (Hymenoptera: Braconidae) in Ceratitis capitata and Anastrepha fraterculus (Diptera: Tephritidae).

An Acad Bras Cienc 2021 22;93(4):e20190935. Epub 2021 Oct 22.

Secretaria de Agricultura, Pecuária e Desenvolvimento Rural, Departamento de Diagnóstico e Pesquisa Agropecuária, R. Gonçalves Dias, 570, 90130-060 Porto Alegre, RS, Brazil.

Diachasmimorpha longicaudata is the most used braconid in biological control programs for Tephritidae fruit flies worldwide. The aim of this work was to assess the functional response and preference of this parasitoid to larvae of Ceratitis capitata and Anastrepha fraterculus, in different densities of hosts. The functional response of females of D. Read More

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October 2021

Dynamic prediction model of spontaneous combustion risk in goaf based on improved CRITIC-G2-TOPSIS method and its application.

PLoS One 2021 27;16(10):e0257499. Epub 2021 Oct 27.

School of Coal Engineering, Shanxi Datong University, Datong, P.R. China.

Due to the problems related to the numerous factors affecting the spontaneous combustion of goaf coal, such as sudden, uncertain, and dynamic changes, and the fact that the weight of the indexes in the prediction model of the spontaneous combustion risk is difficult to determine, an improved Criteria Importance Through Inter-criteria Correlation (CRITIC) modified Technique for Order of Preference by Similarity to Ideal Solution G2-(TOPSIS) dynamic prediction model of goaf spontaneous combustion was developed. An optimal decision-making model was established by introducing the Euclidean distance function, and the function-driven type G2 weighting method was modified using the differential-driven type weighting method of the CRITIC. In addition, the comprehensive weights of each index were obtained. Read More

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October 2021

Smooth versus Textured Implant Breast Reconstruction: Patient-Reported Outcomes and Complications.

Plast Reconstr Surg 2021 Nov;148(5):959-967

From the Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center.

Background: The association between textured surface breast implants and breast implant-associated anaplastic large cell lymphoma has led to an increase in surgical procedures to exchange textured devices to smooth surface implants. Because patient satisfaction is an integral part of breast reconstruction, the purpose of this study was to compare patient-reported outcomes between smooth and textured implant recipients.

Methods: Patients aged 18 years or older who underwent implant-based postmastectomy breast reconstruction with either smooth or textured devices from 2009 to 2017 and completed the BREAST-Q patient-reported outcome measure following reconstruction were included in this analysis. Read More

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November 2021

Distinct Roles of Type I and Type III Interferons During a Native Murine β Coronavirus Lung Infection.

J Virol 2021 Oct 27:JVI0124121. Epub 2021 Oct 27.

Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.

Coronaviruses are a major healthcare threat to humankind. Currently, the host factors that contribute to limit disease severity in healthy young patients are not well defined. Interferons are key antiviral molecules, especially type I and type III interferons. Read More

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October 2021

New Topical Therapies for Psoriasis.

Am J Clin Dermatol 2021 Oct 27. Epub 2021 Oct 27.

Department of Dermatology, Centro Hospitalar Universitário do Porto, Centro Hospitalar do Porto, Edifício das Consultas Externas, Ex. CICAP, Rua D. Manuel II, s/n, 4100, Porto, Portugal.

Psoriasis is a chronic immune-mediated skin disease with a significant impact on patients' quality of life. Mild-to-moderate forms of the disease usually require long-term topical treatment, but prolonged use of corticosteroids and vitamin D analogues is limited by adverse effects. With further understanding of psoriasis pathogenesis, new molecules are emerging aiming to fulfil these clinical needs. Read More

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October 2021

Population pharmacokinetic/pharmacodynamic assessment of imipenem/cilastatin/relebactam in patients with hospital-acquired/ventilator-associated bacterial pneumonia.

Clin Transl Sci 2021 Oct 27. Epub 2021 Oct 27.

Merck & Co., Inc., Kenilworth, New Jersey, USA.

In the phase III RESTORE-IMI 2 study (ClinicalTrials.gov: NCT02493764), the combination antibacterial agent imipenem/cilastatin/relebactam (IMI/REL) demonstrated noninferiority to piperacillin/tazobactam for the end points of all-cause mortality at day 28 and favorable clinical response at the early follow-up visit in adult participants with gram-negative hospital-acquired bacterial pneumonia/ventilator-associated bacterial pneumonia (HABP/VABP). Existing population pharmacokinetic models for imipenem (IPM) and REL were updated using data from patients with HABP/VABP from RESTORE-IMI 2. Read More

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October 2021

Glucose 6-P dehydrogenase delays the onset of frailty by protecting against muscle damage.

J Cachexia Sarcopenia Muscle 2021 Oct 26. Epub 2021 Oct 26.

Freshage Research Group, Department of Physiology, School of Medicine, University of Valencia, CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain.

Background: Frailty is a major age-associated syndrome leading to disability. Oxidative damage plays a significant role in the promotion of frailty. The cellular antioxidant system relies on reduced nicotinamide adenine dinucleotide phosphate (NADPH) that is highly dependent on glucose 6-P dehydrogenase (G6PD). Read More

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October 2021

Blood meal analysis of tsetse flies ( : Glossinidae) reveals higher host fidelity on wild compared with domestic hosts.

Wellcome Open Res 2021 23;6:213. Epub 2021 Aug 23.

Institute of Biodiversity, Animal Health and Comparative Medicine (BAHCM), University of Glasgow, University Place, Glasgow, G12 8QQ, UK.

Changes in climate and land use can alter risk of transmission of parasites between domestic hosts and wildlife, particularly when mediated by vectors that can travel between populations. Here we focused on tsetse flies (genus ), the cyclical vectors for both Human African Trypanosomiasis (HAT) and Animal African Trypanosomiasis (AAT). The aims of this study were to investigate three issues related to from Kenya: 1) the diversity of vertebrate hosts that flies fed on; 2) whether host feeding patterns varied in relation to type of hosts, tsetse feeding behaviour, site or tsetse age and sex; and 3) if there was a relationship between trypanosome detection and host feeding behaviours or host types. Read More

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Monoclonal antibody-mediated neutralization of SARS-CoV-2 in an IRF9-deficient child.

Proc Natl Acad Sci U S A 2021 Nov;118(45)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children 75015 Paris, France;

We describe an unvaccinated child at risk for life-threatening COVID-19 due to an inherited deficiency of IRF9, which governs ISGF-3-dependent responses to type I and III interferons (IFN). She was admitted, with a high nasal SARS-CoV-2 load on day 1 of upper respiratory tract infection. She was viremic on day 2 and received casirivimab and imdevimab. Read More

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November 2021

Surgery in Locally Advanced Esophageal Adenocarcinoma for Patients of Advanced Age or Significant Comorbidities.

Int J Radiat Oncol Biol Phys 2021 Nov;111(3S):e49

Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX.

Purpose/objective(s): The addition of surgery to chemoradiation (CRT) for esophageal adenocarcinoma has shown improved overall survival (OS) in many retrospective studies but has not demonstrated improved OS in randomized trials. Patients with comorbidities or advanced age are more likely to be given definitive CRT without surgery. Using the National Cancer Database (NCDB), we aim to identify if there is medical equipoise between trimodality therapy (TMT) with neoadjuvant CRT compared to definitive CRT for patients with locally advanced esophageal adenocarcinoma with advanced age or with significant comorbidities. Read More

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November 2021

Prevalence of Palliative Radiotherapy Abstracts Presented at Annual Scientific Meetings of the Canadian Association of Radiation Oncology: 2009-2020.

Int J Radiat Oncol Biol Phys 2021 Nov;111(3S):e489

Division of Radiation Oncology, Cross Cancer Institute, Edmonton, AB, Canada.

Purpose/objective(s): Approximately half of all radiotherapy is delivered with palliative intent. Clinical research in palliative radiotherapy (PRT) aims to manage symptoms, improve quality of life (QoL), evaluate supportive care interventions, and determine optimal dose-fractionation schedules, amongst other goals. The Canadian Association of Radiation Oncology (CARO) Annual Scientific Meeting (ASM) provides opportunities to discuss new developments and disseminate knowledge. Read More

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November 2021

Genomic Profiling Reveals Novel Predictive Biomarkers for Chemo-Radiotherapy Toxicity and Efficacy in Non-Small-Cell Lung Cancer.

Int J Radiat Oncol Biol Phys 2021 Nov;111(3S):e437

Department of Radiation Oncology, Shandong Cancer Hospital, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.

Purpose/objective(s): Chemo-radiotherapy (CRT) remains the main treatment modality for non-small-cell lung cancer (NSCLC). However, its clinical efficacy is largely limited by individual variations in radio-sensitivity and risk of radiation-induced thoracic toxicity (RITT). There is an urgent need to identify genetic determinants that can explain patients' likelihood to develop recurrence and RITT following CRT. Read More

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November 2021

Clinical Significance of Total Radiation Dose for Patients With Treatment Delays in Stage III Non-Small Cell Lung Cancer.

Int J Radiat Oncol Biol Phys 2021 Nov;111(3S):e431-e432

Fox Chase Cancer Center, Philadelphia, PA.

Purpose/objective(s): Delays during definitive radiation treatment are not uncommon, as highlighted by the ongoing COVID-19 pandemic, and are associated with worse survival. We aim to utilize the National Cancer Database (NCDB) to determine whether prolonged chemoradiation (CRT) treatment time in stage III non-small cell lung cancer (NSCLC) can be compensated for by an increase in total radiation dose.

Materials/methods: We identified 26,101 patients who were treated curatively with CRT using standard doses (59. Read More

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November 2021

The Role of FDG-PET in Staging and Treatment for Stage III NSCLC in Ontario, Canada Between 2009-2017.

Int J Radiat Oncol Biol Phys 2021 Nov;111(3S):e430

Juravinski Cancer Centre, Hamilton, ON, Canada.

Purpose/objective(s): Fluoro-2-deoxyglucose positron-emission tomography (PET) is now considered standard of care in the staging evaluation for new cases of stage III NSCLC however, there is not level 3 evidence demonstrating efficacy of PET. Using retrospective population-based data, we sought to examine the role and timing that PET scans play in influencing treatment choice, as well as survival in patients treated with chemoradiation (CRT) for stage III NSCLC.

Materials/methods: A retrospective cohort of patients diagnosed with stage III NSCLC from 2009-2017 in Ontario, Canada were identified from the Institute of Clinical Evaluative Sciences (ICES). Read More

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November 2021

Predicting Changes in Circulating Immune Cells During Thoracic Radiation in Patients With Lung Cancer.

Int J Radiat Oncol Biol Phys 2021 Nov;111(3S):e425-e426

The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.

Purpose/objective(s): To exam the changes in circulating immune cells during radiation therapy (RT) and study whether radiation dose to organ at risk of immune system is associated with such changes in patients with lung cancer.

Materials/methods: Study population included stage I-IV lung cancer patients treated with RT to the thorax from March 2015 to December 2019 Patients with complete blood counts with differentials at baseline and weekly or bi-weekly during the course of RT were eligible. Circulating immune cells, including rapidly circulating ones in the heart, lung and blood vessels, and slowly circulating ones in the lymphatic system and blood reservoirs (a portion of veins/capillaries), were considered as a surrogate for organ at risk of immune system. Read More

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November 2021

Tumor Infiltrating Lymphocytes (TILs) and T Cell Fraction in Human Papillomavirus (HPV) Associated Oropharyngeal Squamous Cell Carcinoma.

Int J Radiat Oncol Biol Phys 2021 Nov;111(3S):e409

Mayo Clinic, Rochester, MN.

Purpose/objective(s): The percentage of tumor infiltrating lymphocytes (TILs) is indicative of immune response and prognostic in many malignancies, although TILs data within HPV associated oropharyngeal cancer are limited. Our prior analyses of HPV associated malignancy revealed that both a higher fraction of T cells (TCF) to total cells present in the primary tumor specimen and a higher percentage of TILs were associated with a decreased chance of cancer recurrence. Herein, we investigated the relationship between these two immune related prognostic factors, TILs and TCF. Read More

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November 2021

Predictive Value of Ki-67 for Neoadjuvant Chemotherapy in Locally Advanced Nasopharyngeal Carcinoma.

Int J Radiat Oncol Biol Phys 2021 Nov;111(3S):e387

Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

Purpose/objective(s): To assess the predictive value of Ki-67 expression for adjuvant chemotherapy in patients with locally advanced nasopharyngeal carcinoma (LA-NPC).

Materials/methods: The authors retrospectively evaluated 1374 patients with stage III-IVa nasopharyngeal carcinoma in Sichuan Cancer Hospital from 2013 to 2019, of which 638 patients received induction chemotherapy plus concurrent chemoradiotherapy (IC+CCRT), and 736 patients received concurrent chemoradiotherapy (CCRT) alone. Clinical and pathological features of the patients with LA-NPC were retrieved from the hospital records. Read More

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November 2021

Financial Toxicity in Women with Breast Cancer Receiving Radiotherapy: Final Results of a Prospective Observational Study.

Int J Radiat Oncol Biol Phys 2021 Nov;111(3S):e166

University of Louisville, Department of Radiation Oncology, Louisville, KY.

Purpose/objective(s): Financial toxicity (FT), encompassing costs from both direct medical expenses and indirect sources of financial strain, is an increasingly recognized dilemma for cancer patients. We sought to quantify the burden of FT present in a prospective cohort of women with breast cancer (BC) receiving radiotherapy (RT), identify clinically relevant predictors of FT, and to correlate FT with health-related quality of life (QoL) using validated instruments.

Materials/methods: After signing informed consent, consecutive patients with stage 0-III BC completed the Functional Assessment of Cancer Therapy-G7 QoL score (FACT-G7), a tailored FT questionnaire, and the Comprehensive Score for Financial Toxicity (COST) score-a measure of FT validated in cancer patients. Read More

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November 2021

Identification of De Novo Pyrimidine Synthesis as a Targetable Vulnerability in a Novel IDH1 Mutant Engineered Astrocytoma Model.

Int J Radiat Oncol Biol Phys 2021 Nov;111(3S):S86

Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX.

Purpose/objective(s): Despite high prevalence of IDH1-R132H mutations in grade II-III gliomas, effective therapies remain limited. We sought to identify tumor-specific vulnerabilities induced by the IDH1-R132H oncogene and test the translational relevance of targeting them using a new genetically engineered mouse model (GEMM) of IDH1 mutant anaplastic astrocytoma.

Materials/methods: We conducted a synthetic lethality screen using isogenic IDH1 mutant and IDH1 wild-type (WT) glioma cells and a novel drug screening platform developed by our group, called MAPS. Read More

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November 2021

The equine mesenchymal stromal cell secretome inhibits equid herpesvirus type 1 strain Ab4 in epithelial cells.

Res Vet Sci 2021 Oct 20;141:76-80. Epub 2021 Oct 20.

Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, 14853, NY, United States. Electronic address:

Equid herpesvirus 1 (EHV-1) outbreaks occur when virus spreads from infected horses to in-contact horses, primarily via nasal shedding. This study evaluated the efficacy of factors secreted by equine peripheral blood derived mesenchymal stromal cells (PB-MSCs), collectively named the secretome, to inhibit the growth of EHV-1 in (i) 2D epithelial cell cultures (RK-13) in vitro, (ii) 3D equine nasal explants in vitro and (iii) an EHV-1 infection mouse model in vivo. The PB-MSC secretome was found to inhibit EHV-1 in RK-13 cells as well as in the epithelium of equine nasal explants. Read More

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October 2021

Disease modeling on tumor organoids implicates AURKA as a therapeutic target in liver metastatic colorectal cancer.

Cell Mol Gastroenterol Hepatol 2021 Oct 23. Epub 2021 Oct 23.

German Cancer Research Center (DKFZ), Heidelberg, Germany; German Cancer Consortium (DKTK), Partner site Munich, Germany; DKTK Research Group, Oncogenic Signaling Pathways of Colorectal Cancer, Institute of Pathology, Ludwig-Maximilians-University (LMU) Munich, Germany; Institute of Pathology, Ludwig-Maximilians-University (LMU) Munich, Germany. Electronic address:

Background & Aims: Patient-derived tumor organoids recapitulate the characteristics of colorectal cancer (CRC) and provide an ideal platform for preclinical evaluation of personalized treatment options. We aimed to model the acquisition of chemotolerance during first-line combination chemotherapy in metastatic CRC organoids.

Methods: We performed next generation sequencing to study the evolution of KRAS wild-type CRC organoids during adaptation to irinotecan-based chemotherapy combined with EGFR-inhibition. Read More

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October 2021

A Validated Pre-Operative Risk Prediction Tool For Discharge to Skilled Nursing or Rehabilitation Facility Following Anatomic or Reverse Shoulder Arthroplasty.

J Shoulder Elbow Surg 2021 Oct 23. Epub 2021 Oct 23.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA.

Background: As bundled payment models continue spread, understanding the primary drivers of cost excess helps providers avoid penalties and ensure equal healthcare access. Recent work has shown discharge to rehabilitation and skilled nursing facilities (SNF) to be a primary cost driver in total joint arthroplasty, and an accurate preoperative risk calculator for shoulder arthroplasty would not only help counsel patients in clinic during shared decision-making conversations, but also identify high-risk individuals who may benefit from preoperative optimization and discharge planning.

Methods: Shoulder arthroplasty cohorts from two geographically diverse, high-volume centers were reviewed, including 1,773 cases from Institution #1 (56% anatomic) and 3,637 from Institution #2 (50% anatomic). Read More

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October 2021

Biogenic iron sulfide functioning as electron-mediating interface to accelerate dissimilatory ferrihydrite reduction by Shewanella oneidensis MR-1.

Chemosphere 2021 Oct 23:132661. Epub 2021 Oct 23.

Nanchang Key Laboratory of Microbial Resources Exploitation & Utilization from Poyang Lake Wetland, College of Life Sciences, Jiangxi Normal University, Nanchang, 330022, China; Institute of Advanced Cross-field Science, Qingdao University, Qingdao, 200671, China. Electronic address:

Microbially driven iron and sulfur geochemical cycles co-exist ubiquitously in subsurface environments and are of environmental relevance. Shewanella species (dissimilatory metal-reducing bacteria) are capable of reducing Fe(III)-(oxyhydr)oxide minerals and diverse sulfur sources using corresponding metabolic pathways and producing FeS secondary minerals. In spite of the ability in promoting bacterial extracellular electron transfer (EET), the specific role of FeS in mediating EET between microbe/mineral interface is still unclear. Read More

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October 2021

Precursor to Gas Sensor: A Detailed Study of the Suitability of Copper Complexes as an MOCVD Precursor and their Application in Gas Sensing.

Inorg Chem 2021 Oct 26. Epub 2021 Oct 26.

Centre for Nano Science and Engineering (CeNSE), Indian Institute of Science, Bangalore 560012, India.

There are very few p-type semiconductors available compared to n-type semiconductors for positive sensing response for oxidizing gases and other important electronic applications. Cupric oxide (CuO) is one of the few oxides that show p-type conductivity, useful for sensing oxidizing gases. Many researchers obtained CuO using the chemical and solid-state routes, but uniformity and large-area deposition have been the main issues. Read More

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October 2021

Can Jones-Dole's B-Coefficient be a Consistent Structure-Making/Breaking Marker? Rigorous Molecular-Based Analysis and Critical Assessment of Its Marker Uniqueness.

J Phys Chem B 2021 Oct 26. Epub 2021 Oct 26.

Department of Chemical Engineering, University of Florida, Gainesville, Florida 32611, United States.

We analyzed the consistency, or lack thereof, of the conjectured connection between the sign of Jones-Dole's B-coefficient, or its isobaric-temperature derivative, and the structure-making/breaking ability of a solute in a dilute solution. We sought to shed light on some crucial issues, including (i) whether Jones-Dole's B-coefficient contains any embedded microstructural information, (ii) whether we can either assign any definite foundation to the widely used assumption about the sign of the B-coefficient and its structure-making/breaking trend or provide a rational justification for its use as a structure-making/breaking marker, and (iii) whether we actually need Jones-Dole's B-coefficient and its isobaric-temperature derivative as markers for the interpretation of structure-making/breaking trends. Thus, we first addressed the fundamental (statistical mechanical) microscopic to (thermodynamic) macroscopic foundations of a rigorous approach to the structure-making/breaking ability of a solute, regardless of the type of solvent or nature of the solute-solvent intermolecular interaction asymmetries, and its exact relationships to the resulting solution thermodynamics. Read More

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October 2021

Interferon responses to norovirus infections: current and future perspectives.

J Gen Virol 2021 Oct;102(10)

Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.

Human noroviruses (HuNoVs) are increasingly becoming the main cause of transmissible gastroenteritis worldwide, with hundreds of thousands of deaths recorded annually. Yet, decades after their discovery, there is still no effective treatment or vaccine. Efforts aimed at developing vaccines or treatment will benefit from a greater understanding of norovirus-host interactions, including the host response to infection. Read More

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October 2021

Expression of the Type III Secretion System Genes in Epiphytic Cells on Apple Stigmas Benefits Endophytic Infection at the Hypanthium.

Mol Plant Microbe Interact 2021 Oct 26:MPMI06210152R. Epub 2021 Oct 26.

Department of Plant Pathology and Ecology, The Connecticut Agricultural Experiment Station, New Haven, CT 06504, U.S.A.

causes fire blight on rosaceous plants. One of the major entry points of into hosts is flowers, where proliferates epiphytically on stigmatic and hypanthium surfaces and, subsequently, causes endophytic infection at the hypanthium. The type III secretion system (T3SS) is an important virulence factor in Although the role of T3SS during endophytic infection is well characterized, its expression during epiphytic colonization and role in the subsequent infection is less understood. Read More

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October 2021

Association of Lower Extremity Vascular Disease, Coronary Artery, and Carotid Artery Atherosclerosis in Patients with Type 2 Diabetes Mellitus.

Comput Math Methods Med 2021 16;2021:6268856. Epub 2021 Oct 16.

Arba Minch Institute of Technology, Arba Minch University, Ethiopia.

The motive of this article is to present the case study of patients to investigate the association between the ultrasonographic findings of lower extremity vascular disease (LEAD) and plaque formation. Secondly, to examine the association between the formation of coronary artery and carotid artery atherosclerosis in patients with type 2 diabetes mellitus. 124 patients with type 2 diabetes (64 males and 60 females with the age group 25-78 years) are considered for the research studies who have registered themselves in the Department of Endocrinology and Metabolism from April 2017 to February 2019. Read More

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October 2021

Effect of Applying Binocular Visual Training after Slanted Lateral Rectus Recession on Orthophoric Rate and Binocular Visual Function Recovery on Patients with Convergence Insufficiency-Type Intermittent Exotropia.

Evid Based Complement Alternat Med 2021 16;2021:7202319. Epub 2021 Oct 16.

Department of Strabismus and Pediatric Ophthalmology, Hebei Eye Hospital, Xingtai 054000, Hebei Province, China.

Objective: To explore the effect of applying binocular visual training after slanted lateral rectus recession on orthophoric rate and binocular visual function recovery on patients with convergence insufficiency-type intermittent exotropia (CI-IXT).

Methods: A total of 76 CI-IXT child patients treated at the Strabismus and Pediatric Ophthalmology Department of our hospital from June 2019 to June 2020 were selected as the research objects, and those who met the inclusion criteria were equally divided into group A (63 eyes) and group B (61 eyes) according to the sealed envelope randomization. All child patients accepted the slanted lateral rectus recession, and after that, those in group A accepted the binocular visual training and those in group B accepted the conventional visual function rehabilitation training, so as to compare their position of eye, the best corrected visual acuity, etc. Read More

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October 2021