15,795 results match your criteria twin pregnancies


Pregnancy related and postpartum admissions to intensive care unit in the obstetric tertiary care center - an 8-year retrospective study.

Ginekol Pol 2021 Apr 12. Epub 2021 Apr 12.

Department of Obstetrics and Perinatology, Jagiellonian University Medical College, Cracow, Poland.

Objectives: The purpose of the study was to analyze the incidence of maternal morbidity and mortality of pregnant and postpartum women admitted to the intensive care unit (ICU).

Material And Methods: Retrospective analysis of all pregnant and postpartum patients admitted to ICU of the obstetric tertiary care center between January 1, 2007 and December 31, 2014.

Results: A total of 266 patients with pregnancy and postpartum related morbidity were admitted to ICU (12. Read More

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A case of total hysterectomy due to massive maternal bleeding immediately after fetoscopic laser surgery for twin-twin transfusion syndrome.

J Obstet Gynaecol Res 2021 Apr 11. Epub 2021 Apr 11.

Department of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Ube, Japan.

Twin-twin transfusion syndrome (TTTS) complicates approximately 10% of monochorionic twin pregnancies and is associated with almost 90% mortality if left untreated. Fetoscopic laser photocoagulation (FLP) is the first-line therapy for TTTS, and an overall twin survival rate of 75% and at least one survival rate of 90% have been established. We report a case of TTTS complicated with bleeding from the uterine wall by inserting the procedure after FLP. Read More

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Cell-free DNA testing of maternal blood in screening for trisomies in twin pregnancy: cohort study at 10-14 weeks and updated meta-analysis.

Ultrasound Obstet Gynecol 2021 Apr 10. Epub 2021 Apr 10.

Harris Birthright Research Centre of Fetal Medicine, King's College Hospital, London, UK.

Objective: To expand the limited knowledge on cell-free (cf)DNA analysis of maternal blood for trisomies 21, 18 and 13 in twin pregnancies by updating the data from the Fetal Medicine Foundation (FMF) on prospective first trimester screening and those arising from systematic review of the literature.

Methods: The FMF data were derived from prospective screening for trisomies 21, 18 and 13 in twin pregnancies at 10 -14 weeks' gestation using the Harmony® prenatal test of Roche/Ariosa Diagnostics, Inc. Search of Medline, Embase, CENTRAL (The Cochrane Library), ClinicalTrials. Read More

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Relaparotomy post-cesarean delivery: characteristics and risk factors.

Arch Gynecol Obstet 2021 Apr 10. Epub 2021 Apr 10.

Department of Obstetrics and Gynecology, Department of Neonatology, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel.

Purpose: Relaparotomy following cesarean delivery (CD) is performed at a rate of 0.2-1% of CD. The objective of the present study was to identify risk factors for relaparotomy following CD, and to examine whether there is a difference in the risk of relaparotomy between CD performed during different hours of the day. Read More

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[Results of non-invasive prenatal testing for 2473 women with twin pregnancy].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2021 Apr;38(4):313-316

Genetic and Prenatal Diagnosis Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.

Objective: To assess the value of non-invasive prenatal testing (NIPT) for the detection of fetal chromosomal aneuploidies in women with twin pregnancy.

Methods: A total of 2473 women with twin pregnancy underwent the NIPT test to assess the risk for fetal chromosomal aneuploidies from January 2016 to September 2019. Those with a high risk by NIPT were confirmed by amniocentesis or chorionic villus sampling. Read More

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Vitamin D status in women with dichorionic twin pregnancies and their neonates: a pilot study in China.

BMC Pregnancy Childbirth 2021 Apr 8;21(1):279. Epub 2021 Apr 8.

International Collaborative Laboratory of Reproduction and Development of Chinese Ministry of Education, Chongqing Medical University, Chongqing, 400016, China.

Background: Vitamin D deficiency is a global public health issue in women and children and is associated with adverse impacts on child growth, such as rickets. However, prior studies have mainly focused on measuring vitamin D levels in singleton pregnant women and their offspring, and very limited studies have revealed the prevalence of vitamin D deficiency in twin pregnant women and their offspring. The aim of this study was to investigate vitamin D levels in twin-pregnant women and their neonates. Read More

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Concordance and discordance between maternal and newborn drug test results.

Am J Obstet Gynecol MFM 2021 Apr 5:100366. Epub 2021 Apr 5.

Friend Research Institute, Baltimore MD.

Background: Screening for substance use is recommended during pregnancy and many clinicians rely on urine drug screening to identify newborns at potential risk for withdrawal.

Objective: To determine the concordance and discordance rates between maternal and neonatal drug testing at or near the time of delivery.

Study Design: This retrospective chart review was performed at a single institution that employs universal testing for those who consent. Read More

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Maternal lipid levels in preeclampsia: singleton vs. twin pregnancies.

J Matern Fetal Neonatal Med 2021 Apr 7:1-8. Epub 2021 Apr 7.

Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, PR China.

Objective: To compare the maternal lipid levels in preeclampsia (PE) patients between singleton and twin pregnancies.

Methods: In this retrospective study, pregnant women with PE were divided into singleton group ( = 702) and twin group ( = 198). Serum lipids which include total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were measured and the TC/HDL-C ratio, TG/HDL-C ratio, and LDL-C/HDL-C ratio were calculated and compared between the two groups. Read More

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The Detection, Outcome, and Presentation of Twin-Twin Transfusion Syndrome in Monochorionic Diamniotic Twin Pregnancies Followed with a Protocol of Fortnightly Ultrasound Examination.

Fetal Diagn Ther 2021 Apr 6:1-8. Epub 2021 Apr 6.

Department of Obstetrics and Gynecology, University Hospitals Leuven, Leuven, Belgium.

Background: Evidence to support a fortnightly scan protocol for monochorionic diamniotic (MCDA) pregnancies to detect twin-twin transfusion syndrome (TTTS) is scarce. Also, TTTS-related mortality in an unselected cohort is not well documented. Finally, common knowledge suggests that a more frequent follow-up may pick up the disease at a milder stage, but little is known on the ultrasound findings before the diagnosis. Read More

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A comparative study of two immunoassays of maternal placental growth factor.

Scand J Clin Lab Invest 2021 Apr 6:1-6. Epub 2021 Apr 6.

National Perinatal Epidemiology Centre, University College Cork, Cork, Ireland.

Circulating maternal levels of placental growth factor correlates well with placental function and numerous studies advocate its role to help rule-out preterm pre-eclampsia. A number of automated immunoassay platforms to quantify placental growth factors are currently available. The aim of this study was to highlight the importance of developing and validating appropriate reference ranges and clinical cut-offs for immunoassays, by comparing the results obtained from two different immunoassays of placental growth factor; the Quantikine ELISA and the automated Triage test. Read More

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Individualized embryo selection strategy developed by stacking machine learning model for better in vitro fertilization outcomes: an application study.

Reprod Biol Endocrinol 2021 Apr 5;19(1):53. Epub 2021 Apr 5.

Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095, Jiefang Road, Wuhan, 430030, China.

Background: To minimize the rate of in vitro fertilization (IVF)- associated multiple-embryo gestation, significant efforts have been made. Previous studies related to machine learning in IVF mainly focused on selecting the top-quality embryos to improve outcomes, however, in patients with sub-optimal prognosis or with medium- or inferior-quality embryos, the selection between SET and DET could be perplexing.

Methods: This was an application study including 9211 patients with 10,076 embryos treated during 2016 to 2018, in Tongji Hospital, Wuhan, China. Read More

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Births: Final Data for 2019.

Natl Vital Stat Rep 2021 Apr;70(2):1-51

Objectives-This report presents 2019 data on U.S. births according to a wide variety of characteristics. Read More

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Outcomes of donor versus partner sperm in IUI in women aged 38 years and older.

Int J Gynaecol Obstet 2021 Apr 2. Epub 2021 Apr 2.

Department of Obstetrics and Gynecology, McGill University Health Centre, McGill University, Montreal, QC, Canada.

Objective: To compare pregnancy rates of donor versus partner sperm in intrauterine insemination cycles in women aged 38 years and above.

Methods: A retrospective cohort study was performed using data from 944 women aged 38 to 43 years old who underwent a combined 1596 intrauterine insemination cycles at an academic fertility clinic in Montreal, Canada between February 2009 to April 2018.

Results: Partner sperm was used in 1421 cycles (89. Read More

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Genomic Prediction for Twin Pregnancies.

Animals (Basel) 2021 Mar 16;11(3). Epub 2021 Mar 16.

Zoetis Genetics, 333 Portage Street, Kalamazoo, MI 49007, USA.

Twinning is a multifactorial trait influenced by both genetic and environmental factors that can negatively impact animal welfare and economic sustainability on commercial dairy operations. To date, using genetic selection as a tool for reducing twinning rates on commercial dairies has been proposed, but not yet implemented. In response to this market need, Zoetis (Kalamazoo, MI, USA) has developed a genomic prediction for twin pregnancies, and included it in a comprehensive multitrait selection index. Read More

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Twin-to-Twin Transfusion Syndrome: Diagnostic Imaging and Its Role in Staving Off Malpractice Charges and Litigation.

Diagnostics (Basel) 2021 Mar 4;11(3). Epub 2021 Mar 4.

Department of Anatomical, Histological, Forensic, and Orthopedic Sciences, Sapienza University of Rome, 00161 Rome, Italy.

The study aims to expound upon the imaging-based diagnostic methodologies aimed at identifying twin-to-twin transfusion syndrome (TTTS), a serious, somewhat rare prenatal condition that takes place in pregnancies where identical twins, or other multiples, share a placenta (monochorionic placenta), highlighting how medico-legal outcomes can be affected by provable compliance with consolidated diagnostic guidelines or best practices. It is of utmost importance to produce a prompt identification of TTTS instances; an early diagnosis is in fact critical in order to effectively treat and manage TTTS. By virtue of TTTS being a highly progressive condition, a delay in diagnosis can result in disastrous outcomes; just a few weeks delay in the diagnosis of TTTS can turn out fatal for one or both twins. Read More

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Twin-To-Twin Transfusion Syndrome Donor and Recipient and Their Subsequent Cognitive Functioning in Late Childhood as Juvenile Athletes-A Case Study.

Int J Environ Res Public Health 2021 Mar 4;18(5). Epub 2021 Mar 4.

Institute of Psychology, Faculty of Social Sciences, University of Gdansk, 80-309 Gdansk, Poland.

: It is estimated that twin-to-twin transfusion syndrome (TTTS) occurs in 10-15% of monochorionic twin pregnancies. One of the fetuses takes on the role of donor and the other of recipient. The treatment administered involves serial amnioreduction and laser photocoagulation of the communicating blood vessels. Read More

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May-Thurner Syndrome Is Aggravated by Pregnancy.

Medicina (Kaunas) 2021 Mar 1;57(3). Epub 2021 Mar 1.

Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

This study aims to emphasize that asymptomatic patients with undiagnosed and asymptomatic May-Thurner syndrome (MTS) may firstly develop severe compression during pregnancy. A 40-year-old woman, G1P0, at 22 weeks of twin gestation presented with left lower extremity edema and pain. One twin was structurally normal while the other had bilateral renal agenesis with oligohydramnios. Read More

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Early Ultrasound Identification of Cord Entanglement in Monochorionic Monoamniotic Twin Pregnancy.

Diagnostics (Basel) 2021 Mar 15;11(3). Epub 2021 Mar 15.

Department of Obstetrics and Gynecology, Filantropia Clinical Hospital, 011171 Bucharest, Romania.

Monochorionic monoamniotic pregnancy are considered high risk gestations and the fetal outcome is at times unpredictable. Correct diagnosis and counselling are extremely important, especially regarding the risk of unexpected fetal demise. We present the rare case of a monochorionic monoamniotic twin pregnancy with early identification of cord entanglement and the characteristic ultrasound findings in the first trimester of pregnancy. Read More

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SARS-CoV-2 Infection and Inflammatory Response in a Twin Pregnancy.

Int J Environ Res Public Health 2021 03 17;18(6). Epub 2021 Mar 17.

Institute for Maternal and Child Health "IRCCS Burlo Garofolo", via Dell'istria 65/1, 34124 Trieste, Italy.

There is growing literature about the SARS-CoV-2 pathogenetic effects exerted during pregnancy and whether vertical transmission or premature birth is possible. It is not well known whether changes in the immune system of pregnant women may lead to a marked susceptibility to infectious processes and the risk of adverse maternal and neonatal complications such as preterm birth, spontaneous abortion, hospitalization in an intensive care unit, transmission to the fetus or newborns, and fetal mortality are poorly understood. Along with this ongoing debate, it is not well defined whether, during pregnancy, the role of host susceptibility in producing a specific inflammatory response to SARS-CoV-2 may represent distinctive markers of risk of vertical transmission. Read More

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