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Chest MRI as an emerging modality in evaluation of empyema in children with specific indications: Pilot study.

Pediatr Pulmonol 2021 May 8. Epub 2021 May 8.

Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, India.

Objectives: To assess the diagnostic role of chest magnetic resonance imaging (MRI) for evaluating empyema in children with specific indications.

Methods: Nineteen children (5 to 16 years) with a diagnosis of empyema were enrolled in this prospective study from January 2018 to February 2020. MRI and multidetector computed tomography (MDCT) of the chest were performed within 48 hours of each other. Read More

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Uvular Necrosis After Shoulder Surgery: A Report of Three Cases.

Cureus 2021 Mar 31;13(3):e14233. Epub 2021 Mar 31.

Orthopaedic Surgery, Stanford University School of Medicine, Stanford, USA.

Uvular necrosis is a rare postoperative complication that can manifest from endotracheal tube intubation or laryngeal mask airway placement resulting in compression and restriction of blood flow to the uvula. This report describes three patients who underwent outpatient shoulder surgery under general anesthesia and were subsequently diagnosed with uvular necrosis. Their symptoms included persistent sore throat, dysphagia, odynophagia, and foreign body sensation, with swelling and white exudate on the uvular tip. Read More

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Portable Chest Radiography Immediately after Post-Cardiac Surgery; an Essential Tool for the Early Diagnosis and Treatment of Atelectasis: a Case Report.

Tanaffos 2020 Dec;19(4):418-421

Department of Surgery, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Atelectasis after endobronchial intubation (ETT) is a known complication of general anesthesia. In-bed auscultation of lungs and use of the 21/23 rule are the two suggestive, but not reliable, methods for the early detection of this event; however, none of them guarantees its prevention. The portable chest radiograph (CXR) is a simple, quick method to detect atelectasis and proper placement of the endotracheal tube in the intensive care unit (ICU). Read More

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December 2020

Tracheostomy on infants born in the periviable period: Outcomes at discharge from the neonatal intensive care unit (NICU).

Int J Pediatr Otorhinolaryngol 2021 Apr 27;146:110746. Epub 2021 Apr 27.

Department of Otorhinolaryngology H & N Surgery, University of Maryland School of Medicine and University of Maryland Children's Hospital, Baltimore, MD, USA.

Objectives: Advances in neonatal intensive care have allowed successful resuscitation of children born at the border of viability. However, there has been little change in the incidence of bronchopulmonary dysplasia (BPD) and anatomical upper airway obstruction which may require a tracheostomy in that group. The benefits of the procedure are accompanied by sequelae that impact outcomes. Read More

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Primary malignant melanoma of the esophagus successfully treated with nivolumab: a case report.

J Med Case Rep 2021 May 5;15(1):237. Epub 2021 May 5.

Department of Gastroenterological Surgery, Kawasaki Saiwai Hospital, 31-27 Omiyacho, Saiwai-ku, Kawasaki city, Kanagawa, 212-0014, Japan.

Introduction: Primary malignant melanoma of the esophagus is a rare and aggressive disease that tends to have a poor response to chemotherapies. Previous studies have indicated that currently available treatment for primary malignant melanoma of the esophagus is insufficient. Here, we describe a case of recurrent primary malignant melanoma of the esophagus successfully treated with the immune checkpoint inhibitor nivolumab. Read More

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Whole-Exome Sequencing Identified as a Candidate Gene for Familial Exudative Vitreoretinopathy.

Genet Test Mol Biomarkers 2021 May 4. Epub 2021 May 4.

The Sichuan Provincial Key Laboratory for Human Disease Gene Study, Prenatal Diagnosis Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

Familial exudative vitreoretinopathy (FEVR) is a blinding retinal vascular disease. Clinically, FEVR is characterized by incomplete vascularization of the peripheral retina and pathological neovascularization. Only about 50% of FEVR cases can be explained by known FEVR disease gene variations. Read More

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An uncommon case of nonconvulsive status epilepticus successfully treated with enteral Brivaracetam.

Acta Biomed 2021 Apr 30;92(S1):e2021156. Epub 2021 Apr 30.

Department of Neuroscience, Stroke Unit San Camillo Hospital, Rome.

Background And Aim Of The Work: We present a case of a woman affected by nonconvulsive status epilepticus (NCSE) caused by cerebral hyperperfusion syndrome (CHS) after carotid endarterectomy (CEA) who was successfully treated with Brivaracetam (BRV) administered via nasogastric tube (NGT).

Case Presentation: An 82-years old woman was referred for increasing blood pressure, severe headache and two focal motor seizures on postoperative day four after right CEA. CT scan showed edema of the right hemisphere with a midline shift of 5 mm. Read More

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Computational flow cytometry as a diagnostic tool in suspected-myelodysplastic syndromes.

Cytometry A 2021 May 3. Epub 2021 May 3.

Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, Netherlands.

The diagnostic work-up of patients suspected for myelodysplastic syndromes is challenging and mainly relies on bone marrow morphology and cytogenetics. In this study, we developed and prospectively validated a fully computational tool for flow cytometry diagnostics in suspected-MDS. The computational diagnostic workflow consists of methods for pre-processing flow cytometry data, followed by a cell population detection method (FlowSOM) and a machine learning classifier (Random Forest). Read More

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A ruptured seventeen weeks' ectopic pregnancy: A case report.

J Pak Med Assoc 2021 Feb;71(2(B)):763-765

Department of North Surgery, King Edward Medical University, Mayo Hospital Lahore, Lahore, Pakistan.

Ectopic pregnancy is a common condition with a prevalence of 2% in all pregnancies. Implantation of the developing blastocyst outside the uterine cavity leads to ectopic pregnancy. About 95% of ectopic pregnancies occur in the different segments of the fallopian tubes. Read More

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February 2021

Comparison evaluation between gene Xpert Mtb/Rif and multiplex PCR for rapid diagnosis of mycobacterium tuberculosis.

J Pak Med Assoc 2021 Feb;71(2(B)):636-639

Department of Microbiology, PNS Shifa Hospital, Karachi, Pakistan.

Objective: To compare the efficacy of Gene Xpert mycobacterium tuberculosis-rifampicin and multiplex polymerase chain reacton for the detection of mycobacterium tuberculosis and Rifampicin resistance.

Methods: The cross-sectional validation study was conducted at the Department of Microbiology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan, from March to October 2018, and comprised mycobacterium tuberculosis-positive rifampicin-resistant and rifampicin-susceptible samples, with the latter acting as negative controls. Gene Xpert mycobacterium tuberculosis-rifampicin assasy and multiplex polymerase chain reacton were applied simultaneously and compared with gold standard mycobacterium growth indicator tube 960. Read More

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February 2021

Backward Planning for a Multi-Stage Steerable Needle Lung Robot.

IEEE Robot Autom Lett 2021 Apr 17;6(2):3987-3994. Epub 2021 Mar 17.

Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Lung cancer is one of the deadliest types of cancer, and early diagnosis is crucial for successful treatment. Definitively diagnosing lung cancer typically requires biopsy, but current approaches either carry a high procedural risk for the patient or are incapable of reaching many sites of clinical interest in the lung. We present a new sampling-based planning method for a steerable needle lung robot that has the potential to accurately reach targets in most regions of the lung. Read More

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Postnatal Management in Congenital Lower Urinary Tract Obstruction With and Without Prenatal Vesicoamniotic Shunt.

Front Pediatr 2021 14;9:635950. Epub 2021 Apr 14.

Center for Pediatric, Adolescent and Reconstructive Urology, Medical Faculty Mannheim, University of Medical Center Mannheim, Heidelberg University, Heidelberg, Germany.

Congenital lower urinary tract obstruction (cLUTO) includes a heterogeneous group of conditions caused by a functional or mechanical outlet obstruction. Early vesicoamniotic shunting (VAS) possibly reduces the burden of renal impairment. Postpartum, pediatric urologists are confronted with neonates who have a shunt in place and a potentially impassable urethra with a narrow caliber. Read More

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Case Report: Late-Presenting Congenital Diaphragmatic Hernia With Tension Gastrothorax.

Front Pediatr 2021 14;9:618596. Epub 2021 Apr 14.

Train and Help Babies Organization, Dallas, TX, United States.

A congenital diaphragmatic hernia (CDH) occurs when the abdominal contents protrude into the thoracic cavity through an opening in the diaphragm. The main pathology lies in the maldevelopment or defective fusion of the pleuroperitoneal membranes. Delayed diagnosis in later childhood as in the index case reported here can lead to life-threatening complications such as tension gastrothorax and gastric volvulus. Read More

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Split-filter dual-energy CT pulmonary angiography for the diagnosis of acute pulmonary embolism: a study on image quality and radiation dose.

Quant Imaging Med Surg 2021 May;11(5):1817-1827

Department of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany.

Background: Computed tomography (CT) pulmonary angiography is the diagnostic reference standard in suspected pulmonary embolism (PE). Favorable results for dual-energy CT (DECT) images have been reported for this condition. Nowadays, dual-energy data acquisition is feasible with different technical options, including a single-source split-filter approach. Read More

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A Case of Multiloculated Hydrocephalus.

J Pediatr Neurosci 2020 Oct-Dec;15(4):426-431. Epub 2021 Jan 19.

Department of Neurosurgery, Government Medical College, Thrissur, Kerala, India.

Multiloculated hydrocephalus (MLH) is a disease in which no single treatment has shown to be superior to others. The authors report a pediatric case of postmeningitic MLH diagnosed at the age of 3 months. It was treated with antibiotics and right ventriculoperitoneal (VP) shunt. Read More

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January 2021

Middle ear adenomatous neuroendocrine tumours: single institution experience with five cases.

Clin Otolaryngol 2021 May 1. Epub 2021 May 1.

APHP, Otology, auditory implants and skull base department, Pitié-Salpêtrière Hospital, Paris, France.

Middle ear adenomatous neuroendocrine tumours are extremely rare causes of middle ear masses. Differential diagnosis is of primary importance to decide on the correct management since they require surgery whereas other lesions can be actively watched. CT and MRI show a non-hypervascular lesion, differentiating it from paraganglioma. Read More

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Immunoglobulin isotype compositions of ABO specific antibodies are dependent on the individual patient blood group and blood group specificity: Results from a healthy donor cohort.

J Immunol Methods 2021 Apr 30;494:113053. Epub 2021 Apr 30.

Department of Histocompatibility and Immunogenetics, NHS Blood and Transplant, Birmingham, UK.

Antibodies specific for the blood group ABO system antigens are of clinical significance and immunological interest. Routine clinical methods typically employ direct or indirect haemagglutination methods to measure IgM and IgG, respectively. We have developed a simple, single tube method to quantify IgM, IgG, and IgA specific for A and B antigens in order to improve accuracy and reproducibility, and to investigate the relationships between ABO group antibody type, and antibody level. Read More

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The effect of assisted enteral feeding on treatment outcome in dogs with inflammatory protein-losing enteropathy.

J Vet Intern Med 2021 May 1. Epub 2021 May 1.

Department of Clinical Science and Services, Royal Veterinary College, Hatfield, United Kingdom.

Background: The effect of assisted enteral feeding on treatment outcome in dogs with protein-losing enteropathy (PLE) is unknown.

Objectives: To determine if dogs with inflammatory PLE that had an enteral feeding tube placed had better outcome vs dogs with inflammatory PLE without a feeding tube.

Animals: Fifty-seven dogs with inflammatory PLE. Read More

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[Prospects for a passive acoustic research method in otorhinolaryngology].

Vestn Otorinolaringol 2021 ;86(2):66-72

L.I. Sverzhevskiy Research and Clinical Institute of Otorhinolaryngology of the Moscow Healthcare Department, Moscow, Russia.

The authors of the article reviewed acoustic research methods in otorhinolaryngology. All acoustic diagnostic methods are divided into active and passive. Active acoustic methods are based on the emission of acoustic vibrations, in some cases with the subsequent reception and processing of reflected vibrations. Read More

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Improving the Differential Diagnosis of Otitis Media With Effusion Using Wideband Acoustic Immittance.

Ear Hear 2021 Apr 29. Epub 2021 Apr 29.

Department of Research, Boys Town National Research Hospital, Omaha, Nebraska, USA Center for Childhood Deafness, Language and Learning, Boys Town National Research Hospital, Omaha, Nebraska, USA Department of Otolaryngology, Boys Town National Research Hospital, Omaha, Nebraska, USA.

Objectives: The objective of this work is to determine whether there is a systematic effect of middle ear effusion volume on wideband acoustic immittance in children with surgically confirmed otitis media with effusion.

Design: Wideband acoustic immittance was measured in 49 ears from children (9 months to 11 years) who had a diagnosis of otitis media with effusion and compared to 14 ears from children (10 months to 10 years) without a recent history of otitis media. For children with otitis media with effusion, wideband acoustic immittance testing took place in the child's preoperative waiting room before surgical placement of tympanostomy tubes. Read More

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The use of percutaneous-endoscopic rendezvous stenting in a patient with bile duct injury after cholecystectomy-and a unique complication requiring secondary endoscopic intervention.

J Surg Case Rep 2021 Apr 20;2021(4):rjab119. Epub 2021 Apr 20.

Department of Surgery, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, FL, USA.

Bile duct injury (BDI) is a potentially devastating complication after cholecystectomy. Familiarity with the diagnosis and multidisciplinary treatment options is imperative. This report highlights the utility of the rendezvous stenting procedure in a high-risk patient and describes a rare complication involving stent misplacement through the surgical drain. Read More

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Predictors of nasogastric tube removal in patients with stroke and dysphagia.

Int J Rehabil Res 2021 Apr 27. Epub 2021 Apr 27.

Department of Physical Medicine and Rehabilitation Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan, ROC.

Dysphagia is present in 25-50% of patients with stroke. Therefore, studying the probability of nasogastric tube removal in such patients before discharge from the rehabilitation ward is crucial. In this study, we developed a model to predict the outcome of dysphagia in patients with stroke. Read More

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Intradermal Testing Doubles Identification of Allergy among 110 Immunotherapy-Responsive Patients with Eustachian Tube Dysfunction.

Diagnostics (Basel) 2021 Apr 24;11(5). Epub 2021 Apr 24.

Harvard Medical School, Boston, MA 02114, USA.

The purpose of this study was to determine whether the sensitivity advantage of intradermal dilutional testing (IDT) is clinically relevant in patients with obstructive Eustachian tube dysfunction (ETD) or otitis media with effusion (OME). This retrospective, private-practice cohort study compared the sensitivity of skin prick tests (SPT) vs. IDT in 110 adults and children with suspected allergy and OME. Read More

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Impact of Collection Volume and DNA Extraction Method on the Detection of Biomarkers and HPV DNA in First-Void Urine.

Molecules 2021 Apr 1;26(7). Epub 2021 Apr 1.

Centre for the Evaluation of Vaccination (CEV), Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Wilrijk-Antwerp, Belgium.

The potential of first-void (FV) urine as a non-invasive liquid biopsy for detection of human papillomavirus (HPV) DNA and other biomarkers has been increasingly recognized over the past decade. In this study, we investigated whether the volume of this initial urine stream has an impact on the analytical performance of biomarkers. In parallel, we evaluated different DNA extraction protocols and introduced an internal control in the urine preservative. Read More

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Isolated fallopian tubal torsion: Reproductive age case series.

J Obstet Gynaecol Res 2021 Apr 28. Epub 2021 Apr 28.

Department of Obstetrics and Gynecology, University of Health Sciences Umraniye Training and Research Hospital, Istanbul, Turkey.

Aim: To present our experiences in isolated fallopian tubal torsion (IFTT) case series, which are difficult to diagnose, in light of the literature.

Methods: The data of the patients diagnosed with IFTT surgically in our tertiary hospital between 2018 and 2019 were evaluated.

Results: Abdominal lower quadrant pain was present in all nine cases. Read More

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Foreign Body in the Eustachian Tube: A Challenging Diagnosis and Management.

Turk Arch Otorhinolaryngol 2021 Mar 26;59(1):80-83. Epub 2021 Mar 26.

Department of Otorhinolaryngology & Head and Neck Surgery, Hospital Pedro Hispano, Matosinhos, Portugal.

Foreign bodies in the external ear are very common. The same cannot be said about foreign bodies in the Eustachian tube (ET). We report the case of a 63-year-old woman with a history of painless left side otorrhea and hearing loss. Read More

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Superior mesenteric artery syndrome caused by acute weight loss in a 16-year-old polytrauma patient: A rare case report and review of the literature.

Ann Med Surg (Lond) 2021 May 10;65:102284. Epub 2021 Apr 10.

Department of Radiology, Kabul University of Medical Sciences, Kabul, Afghanistan.

Introduction: Superior mesenteric artery syndrome is a rare entity, caused by compression of the duodenum between the superior mesenteric artery and the aorta.

Case Presentation: A 16-year-old male in the inpatient service of our hospital complained of vomiting for two weeks. The patient had a long hospital stay in our center for the management of trauma-related complications, which resulted in significant weight loss despite the parenteral nutrition as he was unable for taking the enteral nutrition due to severe facial traumatic injury. Read More

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Delayed superior epigastric artery pseudoaneurysm following percutaneous radiologic gastrostomy: Treatment by percutaneous embolization with N-butyl cyanoacrylate.

Radiol Case Rep 2021 Jun 12;16(6):1459-1462. Epub 2021 Apr 12.

Department of Vascular Radiology, University Hospital of Saint-Etienne, Saint-Etienne, France.

Percutaneous radiologic gastrostomy (PRG) is a widely used procedure with a low rate of serious complications and with comparable short-term outcomes with percutaneous endoscopy. Hemorrhagic complications are rare (1.4%), and occur usually immediately after the procedure due to direct arterial punctures. Read More

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[Study of cytokines in peripheral blood and lung of rats exposed to hard metal dust].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2021 Apr;39(4):262-265

Department of Occupational Disease, Suzhou Fifth People's Hospital, Suzhou 215137, China.

To study the dynamic changes of cytokines in bronchoalveolar lavage fluid (BALF) and serum of hard metal lung disease (HMLDR) rats. In March 2019, the rats were randomly divided into 6 groups, each group included 8 rats: control (C) group include 3 groups, hard metal (HM) group include 3 groups. 10 mg HM were administered in HM group by using the pulmonary endotracheal tube. Read More

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Surgical repair of a meningoencephalocoele in a kākāpō ().

N Z Vet J 2021 Apr 28:1-8. Epub 2021 Apr 28.

The Nest Te Kōhanga, Wellington Zoo, Wellington, New Zealand.

Case History: A kākāpō () chick hatched on an off-shore island of New Zealand with a small white mass protruding through the cranial skin of the head. The chick's growth followed a normal pattern for kākāpō but at 3 weeks of age the cranium mass was non-reducible and fixed in place and the chick was removed from the island for diagnostic imaging and hand-rearing.

Clinical Findings And Treatment: A computed tomography (CT) examination revealed a full-thickness circular defect in the central cranium with suspected herniation of brain and dura. Read More

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