Nat Prod Res 2020 Jul 20;34(14):2014-2021. Epub 2019 Feb 20.
Department of Organic Chemistry, Faculty of Science, University of Yaounde I, Yaounde, Cameroon.
Two new coruleoellagic acid derivatives, 3,4',5,5',-tetramethylcoruleoellagic acid ; 3',4,4',5,5'-pentamethylcoruleoellagic acid and a new friedelane-type triterpene derivative rinol , were isolated from leaves and trunk bark of (Violaceae) along with seven known compounds including 3,3',4,4',5'-pentamethylcoruleoellagic acid , hexamethylcoruleoellagic acid 28-hydroxyfriedelin friedelin friedelan-3-ol scopoletin and β-sitosterol-3--β-D-glucopyranoside Their structures were elucidated by means of spectroscopic methods including IR, 1D and 2D NMR in conjunction with mass spectrometry. Crude extracts of leaves and trunk bark as well as compounds were evaluated for their antibacterial activities against 7 pathogenic bacterial strains ( ATCC49619, ATCC 43300, ATCC 700603, ATCC 49247, ATCC 25922, HM601, BAA 977). Compound displayed noteworthy activity against with MIC value of 9. Read More