366,205 results match your criteria tris2-butoxyethyl phosphate


Lizard osteoderms - morphological characterisation, biomimetic design and manufacturing based on three species.

Bioinspir Biomim 2021 Sep 15. Epub 2021 Sep 15.

University College London, Mechanical Engineering, London, WC1E 6JE, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.

Osteoderms (OD) are mineralised dermal structures consisting mainly of calcium phosphate and collagen. The sheer diversity of OD morphologies and their distribution within the skin of lizards makes these reptiles an ideal group in which to study ODs. Nonetheless, our understanding of the structure, development, and function of lizard ODs remains limited. Read More

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September 2021

Long-term effect of conventional phosphate and calcitriol treatment on metabolic recovery and catch-up growth in children with PHEX mutation.

J Pediatr Endocrinol Metab 2021 Sep 16. Epub 2021 Sep 16.

Division of Medical Genetics, Department of Medical Genetics, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Objectives: Hereditary hypophosphatemic rickets (HR) is conventionally treated with phosphate and calcitriol. Exploring genotype and phenotypic spectrum of X-linked hypophosphatemic rickets (XLHR), focusing on short-term, long-term, and pubertal impact of conventional treatment was aimed.

Methods: Sixteen patients from 12 unrelated families with HR were analyzed for phosphate regulating endopeptidase homolog X-linked ( mutation. Read More

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September 2021

Development of non-transgenic glyphosate tolerant wheat by TILLING.

PLoS One 2021 15;16(9):e0245802. Epub 2021 Sep 15.

Arcadia Biosciences, Davis, California, United States of America.

Glyphosate (N-phosphonomethyl-glycine) is the world's most widely used broad spectrum, post-emergence herbicide. It inhibits the chloroplast-targeted enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS; EC 2.5. Read More

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September 2021

Apelin-13 Reverses Bupivacaine-Induced Cardiotoxicity via the Adenosine Monophosphate-Activated Protein Kinase Pathway.

Anesth Analg 2021 Oct;133(4):1048-1059

From the Department of Anesthesiology.

Background: Cardiotoxicity can be induced by the commonly used amide local anesthetic, bupivacaine. Bupivacaine can inhibit protein kinase B (AKT) phosphorylation and activated adenosine monophosphate-activated protein kinase alpha (AMPKα). It can decouple mitochondrial oxidative phosphorylation and enhance reactive oxygen species (ROS) production. Read More

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October 2021

First Report of Post-Harvest Gray Mold on Hyacinth bean () Caused by in Korea.

Plant Dis 2021 Sep 15. Epub 2021 Sep 15.

National Academy of Agricultural Science, Crop Protection Division, National Institute of Agricultural Sciences, Rural Development Administration, Wanju 55365, Korea, Wanju, Korea (the Republic of), 55365;

Hyacinth bean ( L.) is a highly proteineous legume under the family . It is native to Africa, cultivated throughout the world, and recently introduced vegetable in Korea. Read More

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September 2021

Leaf spot caused by Colletotrichum fructicola on star anise (Illicium verum) in China.

Plant Dis 2021 Sep 15. Epub 2021 Sep 15.

University of Guelph, Environmental Sciences, 50 Stone Road East, Guelph, Ontario, Canada, N1G2W1;

Star anise (Illicium verum) has been cultivated for centuries in southern China, and its fruit is an important seasoning spice, and can be used as a medicine (Wang et al. 2011). It is grown mainly in Guangxi, Guangdong, Guizhou, and Yunnan provinces, in China. Read More

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September 2021

WATER QUALITY INFLUENCE ON MACROINVERTEBRATE COMMUNITY IN A TROPICAL ESTUARY (BUENAVENTURA BAY).

Integr Environ Assess Manag 2021 Sep 15. Epub 2021 Sep 15.

Universidad Santiago de Cali, Facultad de Ciencias Básicas.

The anthropogenic discharges of inorganic nutrients impact water quality affecting the macroinvertebrate assemblage and food safety. The main objective was to examine the seawater quality and macroinvertebrate dynamics in muddy habitats of Buenaventura Bay, Colombian Pacific. Macroinvertebrates were captured using artisanal trawl nets during different seasons and along four sampling sites. Read More

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September 2021

Catalyst-free Vitrimer Cross-linked By Biomass-derived Compounds with Mechanical Robustness, Reprocessability and Multi-shape Memory Effects.

Macromol Rapid Commun 2021 Sep 15:e2100432. Epub 2021 Sep 15.

Key Laboratory of High-Performance Synthetic Rubber and its Composite Materials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China.

Vitrimerization of thermoset polymers plays an important role in addressing resource recovery and reuse. Vitrimer elastomers with good mechanical properties often require well-designed crosslinking agents or fillers, but this increases processing complexity or reduces vitrimer dynamic properties. In this report, we design a simple green strategy to build a strong vitrimer elastomer. Read More

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September 2021

A simple method for decellularizing a cell-derived matrix for bone cell cultivation and differentiation.

J Mater Sci Mater Med 2021 Sep 15;32(9):124. Epub 2021 Sep 15.

Department of Trauma and Reconstructive Surgery, BG Trauma Center Tübingen, Siegfried Weller Institute for Trauma Research, Eberhard Karls University Tübingen, 72076, Tübingen, Germany.

The extracellular matrix regulates cell survival, proliferation, and differentiation. In vitro two-dimensional cell experiments are typically performed on a plastic plate or a substrate of a single extracellular matrix constituent such as collagen or calcium phosphate. As these approaches do not include extracellular matrix proteins or growth factors, they fail to mimic a complex cell microenvironment. Read More

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September 2021

The Programmed Cell Death Ligand-1/Programmed Cell Death-1 Pathway Mediates Pregnancy-Induced Analgesia via Regulating Spinal Inflammatory Cytokines.

Anesth Analg 2021 Sep 14. Epub 2021 Sep 14.

Department of Obstetrics, Xiangya Hospital, Central South University, Changsha, China.

Background: The maternal pain threshold gradually increases during pregnancy, especially in late pregnancy. A series of mechanisms underlying pregnancy-induced analgesia have been reported. However, these mechanisms are still not completely clear, and the underlying molecular mechanisms need further investigation. Read More

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September 2021

Life Cycle Exposure to Environmentally Relevant Concentrations of Diphenyl Phosphate (DPhP) Inhibits Growth and Energy Metabolism of Zebrafish in a Sex-Specific Manner.

Environ Sci Technol 2021 Sep 15. Epub 2021 Sep 15.

Toxicology Centre, University of Saskatchewan, Saskatoon S7N 5B3, SK, Canada.

Due to commercial uses and environmental degradation of aryl phosphate esters, diphenyl phosphate (DPhP) is frequently detected in environmental matrices and is thus of growing concern worldwide. However, information on potential adverse effects of chronic exposure to DPhP at environmentally realistic concentrations was lacking. Here, we investigated the effects of life cycle exposure to DPhP on zebrafish at environmentally relevant concentrations of 0. Read More

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September 2021

Determination of progesterone (steroid drug) in the semi - solid dosage form (vaginal gel) using a stability - indicating method by RP-HPLC/PDA detector.

Biomed Chromatogr 2021 Sep 15:e5246. Epub 2021 Sep 15.

Department of Chemistry, School of Science, GITAM (deemed to be university) Hyderabad, Rudraram, Sangareddy, Telangana, INDIA.

A simple stability-indicating method was developed and validated for the determination of progesterone (a steroid drug) in the semi-solid dosage form. All the impurities were separated from the main compound with simple stationary phase (Eclipse XDB, C8, 150 mm × 4.6 mm, 5μm). Read More

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September 2021

Conductive hearing loss in the Hyp mouse model of X-linked hypophosphatemia is accompanied by hypomineralization of the auditory ossicles.

J Bone Miner Res 2021 Sep 15. Epub 2021 Sep 15.

Department of Trauma and Orthopaedic Surgery, Division of Orthopaedics, University Medical Center Hamburg-Eppendorf; Hamburg, Germany.

X-linked hypophosphatemia (XLH) is a hereditary musculoskeletal disorder caused by loss-of-function mutations in the PHEX gene. In XLH, increased circulating fibroblast growth factor 23 (FGF23) levels cause renal phosphate wasting and low concentrations of 1,25-dihydroxyvitamin D, leading to an early clinical manifestation of rickets. Importantly, hearing loss is commonly observed in XLH patients. Read More

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September 2021

Identification of causal metabolites related to multiple autoimmune diseases.

Hum Mol Genet 2021 Sep 15. Epub 2021 Sep 15.

Center for Genetic Epidemiology and Genomics, School of Public Health, Medical College of Soochow University, Suzhou, China.

Object: Observational studies provide evidence that metabolites may be involved in the development of autoimmune diseases (ADs), but whether it is causal is still unknown.

Methods: Based on the large-scale GWAS summary statistics, two-sample Mendelian randomization (MR) was performed to evaluate the causal association between human serum metabolites and multiple ADs, which were inflammatory bowel disease (IBD), ulcerative Colitis (UC), crohn's disease (CD), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), type 1 diabetes (T1D), multiple sclerosis (MS), primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC). Comprehensive sensitive analysis was used to validate the robustness of MR results and multivariable MR analysis was conducted to avoid potential pleiotropic effect of other complex traits. Read More

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September 2021

Give priority to abiotic factor of phosphate additives for pig manure composting to reduce heavy metal risk rather than bacterial contribution.

Bioresour Technol 2021 Sep 9;341:125894. Epub 2021 Sep 9.

Organic Recycling Institute (Suzhou) of China Agricultural University, Wuzhong District, Suzhou 215128, China; College of Resources and Environmental Science, Beijing Key Laboratory of Biodiversity and Organic Farming, China Agricultural University, Beijing 100193, China.

Phosphate additives especially superphosphate can reduce nitrogen loss, and increase phosphorus availability in composting. This study investigated the changes of different heavy metals fractions and their relationship with bacterial community and abiotic factors during pig manure composting with adding equimolar HPO, HSO and KHPO. Results showed that both acidic and alkaline labile phosphate increased the potential ecological risk of heavy metals compared to control, but KHPO decreased the accumulation of exchangeable Zn and Mn by 12% and 15% than that with HPO and HSO addition. Read More

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September 2021

Seasonal occurrence, allocation and ecological risk of organophosphate esters in a typical urbanized semi-closed bay.

Environ Pollut 2021 Aug 30;290:118074. Epub 2021 Aug 30.

State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing, 100875, China; Advanced Interdisciplinary Institute of Environment and Ecology, Beijing Normal University, Zhuhai, 519087, China.

In this study, water and sediment samples from the Jiaozhou Bay and surrounding rivers were collected to analyze the seasonal occurrence and allocation of 12 organophosphate esters (OPEs) and the associated ecological risk. The higher contamination of OPEs in the adjacent rivers indicated the impact of terrestrial input. Tris(1-chloropropan-2-yl) phosphate (TCIPP) was the predominant OPE in the four environmental sample groups investigated. Read More

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Zirconium hydroxide nanoparticle encapsulated magnetic biochar composite derived from rice residue: Application for As(III) and As(V) polluted water purification.

J Hazard Mater 2021 Sep 4;423(Pt A):127081. Epub 2021 Sep 4.

College of Natural Resources and Environment, Northwest A&F University, Yangling, Shaanxi Province 712100, China; Key Laboratory of Plant Nutrition and the Agri-environment in Northwest China, Ministry of Agriculture and Rural Affairs, Yangling, Shaanxi Province 712100, China.

Finding a low-cost and suitable adsorbent is still in urgent need for efficient decontamination of As(III) and As(V) elements from the polluted waters. A novel zirconium hydroxide nanoparticle encapsulated magnetic biochar composite (ZBC) derived from rice residue was synthesized for the adsorptive capture of As(III) and As(V) from aqueous solutions. The results revealed that ZBC showed an acceptable magnet separation ability and its surface was encapsulated with lots of hydrous zirconium oxide nanoparticles. Read More

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September 2021

Chemical modification of bamboo activated carbon surface and its adsorption property of simultaneous removal of phosphate and nitrate.

Chemosphere 2021 Aug 31;287(Pt 1):132118. Epub 2021 Aug 31.

School of Chemistry and Environment, Yunnan Minzu University, Kunming, 650500, Yunnan, China. Electronic address:

Zr/CTAB/BAC was prepared by bamboo activated carbon (BAC) functionalised by zirconia chloride octahydrate (ZrOCl·8HO) and Cetyltrimethylammonium bromide (CTAB). The effects of temperature, time, Zr dosage and CTAB concentration on removing phosphate and nitrate (HPO and NO) in wastewater were investigated. The structure of Zr/CTAB/BAC was characterized by SEM, BET, FTIR, XRD and TG, and the kinetics and thermodynamics of adsorption were discussed. Read More

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A zero-valent iron and zeolite filter for nitrate recycling from agricultural drainage water.

Chemosphere 2021 Aug 26;287(Pt 1):131993. Epub 2021 Aug 26.

Department of Plant and Environmental Science, Faculty of Science, University of Copenhagen, Thorvaldsensvej 40, Frederiksberg C, Dk-1871, Denmark.

Nitrate reduction to ammonium followed by ammonium capture and reuse, represent a new pathway to recycle nitrogen, prevent eutrophication, and to save energy used for industrial ammonium production. The present study investigates the principle of nitrogen recycling to agricultural drainage water using a coupled zero-valent iron (ZVI) and zeolite-based filter column system tested in laboratory and field continuous-flow experiments. A 40-day laboratory test showed 82% nitrate removal, of which 70% was converted to ammonium. Read More

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Analysis of herbicide and its applications through a sensitive electrochemical technique based on MWCNTs/ZnO/CPE fabricated sensor.

Chemosphere 2021 Aug 31;287(Pt 1):132086. Epub 2021 Aug 31.

Department of Chemistry, K. L. S. Gogte Institute of Technology (Autonomous), affiliated to Visvesvaraya Technological University Belagavi-590008, Karnataka, India.

The electrochemical performance of linuron (LNR) was studied by fabricating the carbon paste electrode (CPE) using multiwalled carbon nanotubes (MWCNTs) along with zinc oxide (ZnO) nanoparticles (MWCNTs/ZnO/CPE). The influence of electro-kinetic specifications involving steady heterogeneous rate, pH, sweep rate, temperature effect, transfer coefficient, accumulation time, activation energy, as well as the total number of protons and electrons participating in electro-oxidation of LNR has been established using voltammetric techniques like cyclic voltammetry (CV) and square wave voltammetry (SWV). These techniques were applied to investigate LNR in real samples such as soil including water samples. Read More

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OsWRKY108 is an integrative regulator of phosphorus homeostasis and leaf inclination in rice.

Plant Signal Behav 2021 Sep 15:1976545. Epub 2021 Sep 15.

State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, China.

Phosphorus (P), which is taken up by plants as inorganic phosphate (Pi), is one of the most important macronutrients for plant growth and development. Meanwhile, it determines plant architecture in several ways, including leaf inclination. However, the molecular basis underlying the crosstalk between the signaling pathways of plant P homeostasis and architecture maintenance remains elusive. Read More

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September 2021

Sn2PO4I: An Excellent Birefringent Material with Giant Optical Anisotropy in Non π-Conjugated Phosphate.

Angew Chem Int Ed Engl 2021 Sep 15. Epub 2021 Sep 15.

Xinjiang Technical Institute of Physics and Chemistry, Xinjiang Key Laboratory of Electronic Information Materials and Devices, 40-1 South Beijing Road, 830011, Urumqi, CHINA.

Exploring non π-conjugated phosphate birefringent crystal with a large birefringence has been a great challenge. Herein, based on the unique two-dimensional layered structure in KBe2BO3F2 (KBBF), two new compounds, Sn2PO4I and Sn2BO3I, were designed and synthesized successfully, maintaining the layer structural feature and enhancing the optical anisotropy of crystals. Especially, the birefringence of Sn2PO4I is larger than or equal to 0. Read More

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September 2021

Effect of different doses of the catecholamine epinephrine on antioxidant responses of larvae of the flesh fly Sarcophaga dux.

Environ Sci Pollut Res Int 2021 Sep 14. Epub 2021 Sep 14.

University of Rennes, CNRS, ECOBIO [(Ecosystèmes, biodiversité, évolution)] - UMR 6553, 263 Avenue du Gal Leclerc, 74205, F 35000, 35042, Rennes, CS, France.

The production and use of pharmaceutical products have increased over the past decades, and several are considered potential or proved hazardous wastes. When contaminating the environment, they can severely impact biodiversity. The catecholamine epinephrine (adrenaline) is no exception. Read More

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September 2021

Accelerated sunlight photocatalysis through improved electron mobility between g-CN and BiPO nanomaterial.

Environ Sci Pollut Res Int 2021 Sep 14. Epub 2021 Sep 14.

Department of Environmental Engineering, Faculty of Engineering and Green Technology, Universiti Tunku Abdul Rahman, Jalan Universiti, Bandar Barat, 31900, Kampar, Perak, Malaysia.

Herein, we report a detailed study on creating heterojunction between graphitic carbon nitride (g-CN) and bismuth phosphate (BiPO), enhancing the unpaired free electron mobility. This leads to an accelerated photocatalysis of 2,4-dichlorophenols (2,4-DCPs) under sunlight irradiation. The heterojunction formation was efficaciously conducted via a modest thermal deposition technique. Read More

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September 2021

The associations between organophosphate esters and urinary incontinence in the general US population.

Environ Sci Pollut Res Int 2021 Sep 14. Epub 2021 Sep 14.

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Organophosphate esters (OPEs) impact health in many ways. Since its relationship with urinary incontinence remains unknown, we aimed to explore their associations in the US general population. We combined the results of urine specimens test and self-reported urinary incontinence conditions from the National Health and Nutrition Examination Survey (NHANES) 2013-2014 among 2666 participants and then conducted linear regression and logistic regression to analyse associations between log2-transformed OPE concentrations and urinary incontinence. Read More

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September 2021

NADPH debt drives redox bankruptcy: SLC7A11/xCT-mediated cystine uptake as a double-edged sword in cellular redox regulation.

Genes Dis 2021 Nov 25;8(6):731-745. Epub 2020 Nov 25.

Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Cystine/glutamate antiporter solute carrier family 7 member 11 (SLC7A11; also known as xCT) plays a key role in antioxidant defense by mediating cystine uptake, promoting glutathione synthesis, and maintaining cell survival under oxidative stress conditions. Recent studies showed that, to prevent toxic buildup of highly insoluble cystine inside cells, cancer cells with high expression of SLC7A11 (SLC7A11) are forced to quickly reduce cystine to more soluble cysteine, which requires substantial NADPH supply from the glucose-pentose phosphate pathway (PPP) route, thereby inducing glucose- and PPP-dependency in SLC7A11 cancer cells. Limiting glucose supply to SLC7A11 cancer cells results in significant NADPH "debt", redox "bankruptcy", and subsequent cell death. Read More

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November 2021

Therapeutic efficacy of a extract in a rat model of hepatocellular carcinoma: Histopathological aspects.

J Tradit Complement Med 2021 Sep 13;11(5):400-408. Epub 2021 Feb 13.

Department of Anatomy, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.

Hepatocellular carcinoma (HCC) is most common in adults and has a high mortality rate because of a lack of effective treatment options. We investigated the effect of a medicinal plant as a potential source of drugs against HCC. The rhizomes of Pierre (DM), Hua-Khao-Yen in Thai, are commonly used as ingredients for alternative treatment of cancer in Thailand. Read More

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September 2021

Direct measurement of neuronal ensemble activity using photoacoustic imaging in the stimulated Fos-LacZ transgenic rat brain: A proof-of-principle study.

Photoacoustics 2021 Dec 30;24:100297. Epub 2021 Aug 30.

The Richard and Loan Hill Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, USA.

Measuring neuroactivity underlying complex behaviors facilitates understanding the microcircuitry that supports these behaviors. We have developed a functional and molecular photoacoustic tomography (F/M-PAT) system which allows direct imaging of Fos-expressing neuronal ensembles in Fos-LacZ transgenic rats with a large field-of-view and high spatial resolution. F/M-PAT measures the beta-galactosidase catalyzed enzymatic product of exogenous chromophore X-gal within ensemble neurons. Read More

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December 2021

Oral delivery of proteins and peptides: Challenges, status quo and future perspectives.

Acta Pharm Sin B 2021 Aug 29;11(8):2416-2448. Epub 2021 Apr 29.

Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China.

Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules than small molecular drugs due to their high selectivity and efficacy, but fewer side effects. Owing to the poor stability and limited permeability through gastrointestinal (GI) tract and epithelia, the therapeutic PPs are usually administered by parenteral route. Given the big demand for oral administration in clinical use, a variety of researches focused on developing new technologies to overcome GI barriers of PPs, such as enteric coating, enzyme inhibitors, permeation enhancers, nanoparticles, as well as intestinal microdevices. Read More

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Magnetic systems for cancer immunotherapy.

Acta Pharm Sin B 2021 Aug 30;11(8):2172-2196. Epub 2021 Apr 30.

Department of Chemical & Biological Engineering, University of Colorado, Boulder, CO 80303, USA.

Immunotherapy is a rapidly developing area of cancer treatment due to its higher specificity and potential for greater efficacy than traditional therapies. Immune cell modulation through the administration of drugs, proteins, and cells can enhance antitumoral responses through pathways that may be otherwise inhibited in the presence of immunosuppressive tumors. Magnetic systems offer several advantages for improving the performance of immunotherapies, including increased spatiotemporal control over transport, release, and dosing of immunomodulatory drugs within the body, resulting in reduced off-target effects and improved efficacy. Read More

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