5,634 results match your criteria trimester postpartum

Longitudinal changes in HRV across pregnancy and postpartum: Effect of negative partner relationship qualities.

Psychoneuroendocrinology 2021 Apr 21;129:105216. Epub 2021 Apr 21.

Department of Psychiatry & Behavioral Health and the Institute for Behavioral Medicine Research, The Ohio State University Wexner Medical Center, Columbus, OH, USA.

During pregnancy, there are significant physiological changes to support a healthy fetus. Parasympathetic activity normatively decreases across pregnancy, and psychological stress can promote even further decreased heart rate variability (HRV). This study evaluated (1) changes in vagally-mediated HRV from pregnancy to postpartum, (2) changes in vagally-mediated HRV from pregnancy to postpartum based on negative partner relationship qualities, and (3) changes in depressive symptoms from pregnancy to postpartum based on negative partner relationship qualities. Read More

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Associations of Partnership Quality and Father-to-Child Attachment During the Peripartum Period. A Prospective-Longitudinal Study in Expectant Fathers.

Front Psychiatry 2021 20;12:572755. Epub 2021 Apr 20.

Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany.

During the transition to parenthood, a complex network of relationships unfolds between father, mother and the child. Expectant parents begin bonding with their unborn child, with this antenatal process supposedly being predictive for later postnatal attachment and child mental health. At the same time, couples may experience a change in partnership quality. Read More

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Intimate partner violence and positive parenting across early childhood: Comparing self-reported and observed parenting behavior.

J Fam Psychol 2021 May 6. Epub 2021 May 6.

Department of Psychology.

The current study examined self-reported and observed positive (i.e., nurturing, sensitive, and responsive) parenting behavior among women who experienced intimate partner violence (IPV) during pregnancy and through their early parenting years. Read More

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Health care system barriers and facilitators to early prenatal care among diverse women in Florida.

Birth 2021 May 5. Epub 2021 May 5.

Chiles Center, Sunshine Education and Research Center, University of South Florida College of Public Health, Tampa, FL, USA.

Background: Worldwide, women continue to experience barriers to accessing early prenatal care. Given the unique nature of the United States health care system, this study aimed to identify barriers and facilitators to early prenatal care reported by women in Florida.

Methods: A mixed-methods study of postpartum women with entry to care after 14 weeks' gestation was conducted at a tertiary care hospital in Florida. Read More

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Use of Ballistocardiography to Monitor Cardiovascular Hemodynamics in Preeclampsia.

Womens Health Rep (New Rochelle) 2021 20;2(1):97-105. Epub 2021 Apr 20.

Division of Cardiology, Department of Internal Medicine, University of California San Francisco, San Francisco, California, USA.

Pregnancy requires a complex physiological adaptation of the maternal cardiovascular system, which is disrupted in women with pregnancies complicated by preeclampsia, putting them at higher risk of future cardiovascular events. The measurement of body movements in response to cardiac ejection ballistocardiogram (BCG) can be used to assess cardiovascular hemodynamics noninvasively in women with preeclampsia. Using a previously validated, modified weighing scale for assessment of cardiovascular hemodynamics through measurement of BCG and electrocardiogram (ECG) signals, we collected serial measurements throughout pregnancy and postpartum and analyzed data in 30 women with preeclampsia and 23 normotensive controls. Read More

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Perinatal depression.

Grace Lim

Curr Opin Anaesthesiol 2021 Jun;34(3):233-237

University of Pittsburgh Department of Anesthesiology & Perioperative Medicine.

Purpose Of Review: Perinatal depression is a common and debilitating complication of pregnancy and childbirth. Recent studies have elucidated relationships between acute birth events on depression risk, and novel treatments for postpartum depression have been discovered and approved. This article reviews current understandings about birth events on depression, new screening standards, and novel treatments for postpartum depression. Read More

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Aortic dissection during pregnancy and postpartum.

J Card Surg 2021 Apr 29. Epub 2021 Apr 29.

Department of Ultrasound, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.

Background: Patients with aortic dissection during pregnancy and postpartum period exhibit a high mortality. At present, a complete overview of aortic dissection during pregnancy and postpartum period is lacking. ​Methods: This systematic review included 80 reports published from 2000 to 2020, comprising a total study population of 103 patients with aortic dissection. Read More

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Maternal Serum Angiopoietin-Like 3 Levels in Healthy and Mild Preeclamptic Pregnant Women.

Front Endocrinol (Lausanne) 2021 13;12:670357. Epub 2021 Apr 13.

Department of Physiology, Universidad Nacional de Colombia, Bogota, Colombia.

Objective: Angiopoietin-like protein 3(ANGPTL3) is an important regulator of lipoprotein metabolism in the fed state by inhibiting the enzyme lipoprotein lipase in oxidative tissues. However, the possible role of ANGPTL3 throughout gestation and its relationship with hormonal and biochemical variables are still unknown. The aim of this study was to determinate serum ANGPTL3 level in healthy non-pregnant women, during healthy and preeclamptic pregnancy and postpartum. Read More

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Leisure-Time Physical Activity before and during Pregnancy Is Associated with Improved Insulin Resistance in Late Pregnancy.

Int J Environ Res Public Health 2021 Apr 21;18(9). Epub 2021 Apr 21.

Program for Pregnancy and Postpartum Health, University of Alberta, Edmonton, AB T6G 2E1, Canada.

A total of 83 third trimester pregnant women were recruited to examine the role of pre-pregnancy versus late-pregnancy physical activity on maternal insulin resistance. Principal component analysis plots demonstrated a distinction between the high and low Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) groups. The variation was driven primarily by exercise prior to and during pregnancy. Read More

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Breastfeeding Education and Support to Improve Early Initiation and Exclusive Breastfeeding Practices and Infant Growth: A Cluster Randomized Controlled Trial from a Rural Ethiopian Setting.

Nutrients 2021 Apr 6;13(4). Epub 2021 Apr 6.

Faculty of Medicine, University of Oslo, 0316 Oslo, Norway.

Although peer-led education and support may improve breastfeeding practices, there is a paucity of evidence on the effectiveness of such interventions in the Ethiopian context. We designed a cluster-randomized trial to evaluate the efficacy of a breastfeeding education and support intervention (BFESI) on infant growth, early initiation (EI), and exclusive breastfeeding (EBF) practices. We randomly assigned 36 clusters into either an intervention group ( = 249) receiving BFESI by trained Women's Development Army (WDA) leaders or a control group ( = 219) receiving routine care. Read More

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Continuous glucose monitoring and insulin pump therapy in pregnant women with type 1 diabetes mellitus.

Ginekol Pol 2021 Apr 29. Epub 2021 Apr 29.

Department of Metabolic Diseases, University Hospital, Cracow, Poland.

Objectives: We examined the impact of continuous subcutaneous insulin infusion (CSII) and continuous glucose moni-toring systems (CGM) during pregnancy in women with pre-gestational type 1 diabetes (T1DM) on glycemic control and subsequent adverse outcomes.

Material And Methods: In this observational, one-center study we analyzed records of consecutive 109 T1DM pregnancies (2016-2017). The final analyzed group consisted of 81 singleton pregnancies who met inclusion and exclusion criteria. Read More

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Towards elimination of mother-to-child transmission of HIV in Rwanda: a nested case-control study of risk factors for transmission.

BMC Pregnancy Childbirth 2021 Apr 28;21(1):339. Epub 2021 Apr 28.

Basel Institute for Clinical Epidemiology and Biostatistics, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.

Background: Mother-to-child HIV transmission (MTCT) has substantially declined since the scale-up of prevention programs around the world, including Rwanda. To achieve full elimination of MTCT, it is important to understand the risk factors associated with residual HIV transmission, defined as MTCT at the population-level that still occurs despite universal access to PMTCT.

Methods: We performed a case control study of children born from mothers with HIV with known vital status at 18 months from birth, who were followed in three national cohorts between October and December 2013, 2014, and 2015 in Rwanda. Read More

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Prenatal screening for Down syndrome: popularity, perceptions and factors associated with acceptance or refusal of testing.

J Matern Fetal Neonatal Med 2021 Apr 28:1-5. Epub 2021 Apr 28.

Department of Genetics, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Background: Prenatal screening tests for aneuploidies have become increasingly used in maternal and fetal medicine. Given that all pregnancies associate a potential risk of Down syndrome, adequate knowledge of the tests, and their characteristics as well as facilitating decision-making autonomy are fundamental rights that must be respected.

Objectives: Identification of the popularity of the tests, their perception and the factors associated with the acceptance or refusal to perform them. Read More

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Antenatal Depression Symptoms Among Pregnant Women Seeking Health Services in Erbil, Iraq.

Matern Child Health J 2021 Apr 27. Epub 2021 Apr 27.

College of Nursing, Hawler Medical University, Erbil, Iraq.

Introduction: Maternal depression, which includes depression in the prenatal and postpartum periods, is estimated to affect between 10 and 20% of women globally but the rate is higher in the Middle East. Research focused on maternal depression in Iraq is limited to one study focused on postpartum depression. This paper identifies the prevalence and factors associated with antenatal depression among pregnant Iraqi women. Read More

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Salivary Proteomic Profiling Identifies Role of Neutrophil Extracellular Traps Formation in Pregnancy Gingivitis.

Immunol Invest 2021 Apr 26:1-17. Epub 2021 Apr 26.

Singapore Oral Microbiomics Initiative, National Dental Research Institute Singapore, National Dental Center Singapore.

Pregnancy gingivitis peaks during mid-pregnancy and resolves transiently towards the postpartum period. However, the role of maternal immune response in orchestrating gingival inflammation has not yet been fully understood. Hence, in this study, we examined the salivary protein profile during the three trimesters of pregnancy, in context to pregnancy gingivitis, employing iTRAQ-based quantitative proteomics. Read More

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Exposure to heavy metals and trace minerals in first trimester and maternal blood pressure change over gestation.

Environ Int 2021 Apr 23;153:106508. Epub 2021 Apr 23.

Department of Epidemiology, Johns Hopkins Bloomberg of School of Public Health, Baltimore, MD, USA; Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD, USA. Electronic address:

Background: While several heavy metals and trace minerals have been linked with hypertensive disorders during pregnancy (HDP) in women, no studies have estimated the relationship of exposure to these chemicals, both independently and as a mixture, with systolic blood pressure (SBP) or diastolic blood pressure (DBP) over gestation.

Objectives: We examined individual and joint effects of 1 trimester chemicals with SBP and DBP over gestation, and whether those chemicals were associated with HDP.

Methods: We used data from 1832 non-obese pregnant women with low-risk antenatal profiles from the Eunice Kennedy Shriver National Institute of Child Health and Human Development Fetal Growth Studies - Singleton cohort (2009-2013). Read More

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Unidirectional and bidirectional links between maternal depression symptoms and infant sleep problems.

J Sleep Res 2021 Apr 26:e13363. Epub 2021 Apr 26.

School of Psychology, University of Minho, Braga, Portugal.

The present study explored (a) the unidirectional and bidirectional links between maternal depression symptoms and infant sleep problems and (b) the moderating role of the infant's sex on these unidirectional and bidirectional links. Mothers (N = 312) completed measures of depression symptoms at the third pregnancy trimester, and measures of depression symptoms and infant sleep problems at 2 weeks, and at 3 and 6 months postpartum. The findings revealed: (a) a main unidirectional link between maternal depression symptoms during the third trimester and infant sleep problems, particularly on infant unsettled sleep and daytime sleepiness at 3 and 6 months; (b) bidirectional links between maternal postpartum depression symptoms and infant unsettled sleep at 2 weeks, 3 and 6 months of life; and (c) the reported links between maternal depression symptoms and infant sleep problems occur specifically in boys and their mothers. Read More

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Flexible Scheduling Policy for Pregnant and New Parent Residents: A Descriptive Pilot Study.

AEM Educ Train 2021 Apr 5;5(2):e10504. Epub 2020 Aug 5.

Department of Emergency Medicine Indiana University School of Medicine Indianapolis IN USA.

Objectives: Many physicians complete residency training during optimal childbearing years. The literature shows that working nights or on call can lead to pregnancy complications including miscarriage, preterm labor, and preeclampsia. In addition, infant-parent bonding in the postpartum period is crucial for breastfeeding, health, and well-being. Read More

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Assessment of prurigo of pregnancy in patients without atopic background.

Int J Womens Dermatol 2020 Dec 30;6(5):384-389. Epub 2020 Jun 30.

Department of Dermatology, Alpert Medical School of Brown University, Providence, Rhode Island, United States.

Background: Prurigo of pregnancy (PP), a specific pregnancy dermatosis, has been associated with atopic background in the patient and/or the patient's family. However, this association was not validated in some studies, and cases without atopic background have been reported.

Objective: This study aimed to evaluate the clinical features of PP not related to atopic background and search for comorbid conditions in medical and obstetric records. Read More

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December 2020

Supporting routine psychosocial assessment in the perinatal period: The concurrent and predictive validity of the Antenatal Risk Questionnaire-Revised.

Women Birth 2021 Apr 22. Epub 2021 Apr 22.

Perinatal and Women's Mental Health Unit, St John of God Burwood Hospital, Australia; School of Psychiatry, UNSW Medicine, NSW, Australia; Royal Hospital for Women, NSW, Australia.

Background: Australian clinical practice guidelines support comprehensive psychosocial assessment as a routine component of maternity care.

Aim: To examine the concurrent and predictive validity of the Antenatal Risk Questionnaire-Revised (ANRQ-R) when used across the perinatal period.

Methods: Women completed the ANRQ-R and a diagnostic reference standard (SAGE-SR) in the second and third trimesters and at 3-months postpartum. Read More

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Antepartum and postpartum anemia: a narrative review.

Int J Obstet Anesth 2021 Mar 29:102985. Epub 2021 Mar 29.

Department of Anaesthesia and Pain Medicine, King Edward Memorial Hospital, Perth, WA, Australia.

Antepartum anemia impacts over a third of pregnant women globally and is associated with major maternal and perinatal morbidity, including peripartum transfusion, maternal death, maternal infection, preterm birth, and neurodevelopmental disorders among offspring. Postpartum anemia impacts up to 80% of women in low-income and rural populations and up to 50% of women in Europe and the United States, and is associated with postpartum depression, fatigue, impaired cognition, and altered maternal-infant bonding. Iron deficiency is the most common cause of maternal anemia because of insufficient maternal iron stores at the start of pregnancy, increased pregnancy-related iron requirements, and iron losses due to blood loss during parturition. Read More

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Risk factors for postpartum relapse in women at risk of postpartum psychosis: The role of psychosocial stress and the biological stress system.

Psychoneuroendocrinology 2021 Apr 3;128:105218. Epub 2021 Apr 3.

Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK. Electronic address:

Background: Postpartum psychosis is the most severe psychiatric disorder associated with childbirth, and the risk is particularly high for women with a history of bipolar disorder, schizoaffective disorder or those who have suffered a previous episode of postpartum psychosis. Whilst there is a lot of evidence linking stress to psychosis unrelated to childbirth, the role of stress in the onset of postpartum psychosis has not been fully investigated.

Methods: A prospective longitudinal study of 112 pregnant women, 51 at risk of postpartum psychosis because of a DSM-IV diagnosis of bipolar disorder (n = 41), schizoaffective disorder (n = 6) or a previous postpartum psychosis (n = 4) and 61 healthy women with no past or current DSM-IV diagnosis and no family history of postpartum psychosis. Read More

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The Lutein and Zeaxanthin in Pregnancy (L-ZIP) study-carotenoid supplementation during pregnancy: ocular and systemic effects-study protocol for a randomized controlled trial.

Trials 2021 Apr 22;22(1):300. Epub 2021 Apr 22.

Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah School of Medicine, 65 Mario Capecchi Drive, Salt Lake City, UT, 84132, USA.

Background: Lutein (L), zeaxanthin (Z), and meso-zeaxanthin (MZ), collectively called the macular pigment (MP), are dietary carotenoids that preferentially localize in the macula of the human eye. MP protects the macula from photo-oxidative damage and enhances visual function. Inadequate maternal intake of carotenoids, coupled with the placental transfer of maternal carotenoids to support fetal brain and retina development, potentially put mothers at risk of depletion systemically and in their ocular tissues. Read More

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Perinatal Depression and Anxiety in Women with Multiple Sclerosis: A Population-Based Cohort Study.

Neurology 2021 Apr 21. Epub 2021 Apr 21.

Department of Clinical Medicine, University of Bergen, Norway.

Objective: To assess the occurrence of perinatal depression and anxiety in women before and after diagnosis of multiple sclerosis (MS).

Methods: 114,629 pregnant women were included in the Norwegian Mother, Father and Child Cohort study 1999-2008. We assessed depression and anxiety by questionnaires during and after pregnancy. Read More

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Natalizumab, Fingolimod and Dimethyl Fumarate Use and Pregnancy-Related Relapse and Disability in Women With Multiple Sclerosis.

Neurology 2021 Apr 20. Epub 2021 Apr 20.

Liverpool Hospital, Australia.

Objective: To investigate pregnancy-related disease activity in a contemporary multiple sclerosis (MS) cohort.

Methods: Using data from the MSBase Registry, we included pregnancies conceived after 31 Dec 2010 from women with relapsing-remitting MS or clinically isolated syndrome. Predictors of intrapartum relapse, and postpartum relapse and disability progression were determined by clustered logistic regression or Cox regression analyses. Read More

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Evolution of antibody titres against Epstein-Barr virus and human herpesvirus 6A/B and expression of multiple sclerosis-associated retrovirus in the serum of pregnant multiple sclerosis patients.

Sci Rep 2021 Apr 19;11(1):8441. Epub 2021 Apr 19.

Grupo de Investigación de Factores Ambientales en Enfermedades Degenerativas, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC) / Red Española de Esclerosis Múltiple (REEM), Madrid, Spain.

Epstein-Barr virus (EBV), human herpesvirus 6A/B (HHV-6A/B) and multiple sclerosis (MS)-associated retrovirus (MSRV) have been described as possible MS triggers. We analysed antibody titres against EBV and HHV-6, and MSRV envelope (env) mRNA expression, in the serum of pregnant multiple sclerosis patients (P-MS) to study their possible link to the clinical activity of MS during pregnancy and postpartum and their possible role as relapse predictors. For that purpose, serum samples were collected from 71 pregnant women (50 pregnant MS and 21 pregnant healthy controls-P-HC) during pregnancy and postpartum. Read More

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Pregnancy Associated Granulomatous Mastitis: Clinical Characteristics, Management, and Outcome.

Breastfeed Med 2021 Apr 19. Epub 2021 Apr 19.

Department of Breast, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

We have already known that idiopathic granulomatous mastitis (IGM) is a rare benign chronic inflammatory disorder that can clinically mimic breast carcinoma, especially affects parous women of childbearing age, but there is little literature to report about pregnancy associated granulomatous mastitis (PAGM). The aim of our study is to report and describe the clinical signs, managements, clinical course, and clinical outcomes after treatment of PAGM in our hospital. We retrospectively analyzed 15 pregnant patients who were diagnosed as PAGM in our hospital collected from December 2018 to December 2020 by reviewing medical records and questionnaire survey, including the patients' characteristics, clinical presentations, microbiological workups, tissue pathology, treatment modalities, outcomes, and follow-up data. Read More

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Pregnancy in an adolescent with maple syrup urine disease: Case report.

Mol Genet Metab Rep 2021 Jun 26;27:100745. Epub 2021 Mar 26.

Division of Clinical and Metabolic Genetics, Department of Pediatrics, University of the Philippines - Philippine General Hospital, Manila, Philippines.

Maple syrup urine disease (MSUD, MIM #248600) is an autosomal recessive metabolic disorder that results in elevation of the branched-chain amino acids (BCAA) leucine, isoleucine, and valine. Elevation of BCAA and certain alpha keto-acids is associated with a catabolic state and may result in neurological and developmental delays, feeding problems, and a urine and cerumen odor of maple syrup. Pregnancy is a period of multiple adaptations necessary to support fetal growth and development. Read More

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In-hospital Outcomes and Long-term Survival of Women of Childbearing Age with Aortic Dissection: Results from a Single-Center Database.

J Vasc Surg 2021 Apr 14. Epub 2021 Apr 14.

Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA. Electronic address:

Objective: To define the outcomes and impact of pregnancy in a cohort of women of childbearing age with acute aortic dissection (AAD).

Methods: We reviewed our database of AAD to identify all eligible female patients. Women under the age of 45 were included. Read More

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