92,343 results match your criteria triglyceride cholesterol

Correlation between 25-hydroxyvitamin D level and arterial elasticity in middle-aged and elderly cadres in Guiyang, China: A retrospective observational study.

Medicine (Baltimore) 2021 May;100(18):e25826

Department of General Medicine, Guiyang First People's Hospital.

Abstract: There is evidence that serum 25-hydroxyvitamin D [25-(OH) D] levels may be associated with cardiovascular disease and its risk factors. This study aimed to investigate the relationship between 25-(OH) D levels and blood pressure (BP), blood lipids, and arterial elasticity in middle-aged and elderly cadres in China.In this retrospective study, we included 401 civil servants and cadres aged >42 years who underwent medical examinations at Guiyang Municipal First People's Hospital, China in 2018. Read More

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Polysaccharide MCP extracted from reduces atherosclerosis in LDLR-deficient mice.

Food Funct 2021 May 5. Epub 2021 May 5.

Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui, China.

The pharmaceutical application of fungal polysaccharides has been extensively studied based on their multiple biological activities. However, the effect of Morchella esculenta polysaccharides on the development of atherosclerosis remains unknown. This study aims to investigate the anti-atherosclerotic effect of a novel polysaccharide (MCP) extracted from Morchella esculenta. Read More

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Nutritional Status and Risks of Cognitive Decline and Incident Neurocognitive Disorders: Singapore Longitudinal Ageing Studies.

J Nutr Health Aging 2021 ;25(5):660-667

Tze Pin Ng, Gerontology Research Programme and Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, 9th Floor, 1E Kent Ridge Road, Singapore 119228, Fax: 65-67772191, Tel: 65-67723478, Email:

Background: Studies suggest that nutritional interventions using the whole diet approach such as the Mediterranean diet may delay cognitive decline and dementia onset. However, substantial numbers of older adults are non-adherent to any ideally healthy dietary pattern and are at risk of malnutrition.

Objective: The present study investigated the relationship between global malnutrition risk and onsets of cognitive decline and neurocognitive disorders (NCD), including mild cognitive impairment (MCI) or dementia in community-dwelling older adults. Read More

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January 2021

The Atherogenic Index of Plasma: A Powerful and Reliable Predictor for Coronary Artery Disease in Patients With Type 2 Diabetes.

Angiology 2021 May 5:33197211012129. Epub 2021 May 5.

Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, People's Republic of China.

We evaluated the predictive power of the atherogenic index of plasma (AIP) for coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM). A total of 3278 patients who underwent coronary angiography were consecutively enrolled, including 2052 patients with CAD and 1226 patients with T2DM but without CAD. Patients in the CAD group had higher levels of triglyceride (TG), total cholesterol, low-density lipoprotein cholesterol, AIP and a lower level of high-density lipoprotein cholesterol (HDL-C). Read More

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Arterial structure and function in Africans with HIV for > 5 years: longitudinal relationship with endothelial activation and cardiovascular risk markers.

HIV Med 2021 May 5. Epub 2021 May 5.

Hypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.

Objectives: We aimed to determine whether people with human immunodeficiency virus (PWHIV) have increased measures of arterial injury [carotid intima-media thickness (cIMT)] and large artery stiffness [carotid-femoral pulse wave velocity (cfPWV)] when compared with their counterparts without HIV, and whether baseline markers of endothelial activation and cardiovascular risk are associated with cIMT and cfPWV after 5 years.

Methods: We matched 126 PWHIV from North West Province, South Africa, to 126 without HIV according to age, sex and locality. Cardiovascular risk and endothelial function markers [soluble intracellular adhesion molecule (ICAM-1) and soluble vascular cell adhesion molecule (VCAM-1)] were measured at baseline and cIMT and cfPWV at follow-up. Read More

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Preventive effect of Bacillus mojavensis levan against carbon tetrachloride and cisplatin toxicity: in vivo study.

Environ Sci Pollut Res Int 2021 May 5. Epub 2021 May 5.

Laboratory of Plants Improvement and Valorization of Agroressources, National School of Engineering of Sfax (ENIS), University of Sfax, 3038, Sfax, Tunisia.

This study is the first to investigate the hepato- and nephron-preventive effect of levan from Bacillus mojavensis (BM-levan) against toxicity induced by carbon tetrachloride (CCl) and cisplatin. Thirty-six male albino rats weighing between 230 and 250 g were used for this experiment. The groups received multiples doses of BM-levan and were compared to the untreated group. Read More

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Effectiveness of dietary interventions on cardio-metabolic risk factors in patients with nonalcoholic fatty liver disease: a systematic review and meta-analysis of randomized controlled trials.

Ann Gastroenterol 2021 26;34(3):415-423. Epub 2021 Feb 26.

Liver Transplantation Research Center, Imam Khomeini Hospital complex, Tehran University of Medical Sciences, Tehran, Iran (Maryam Ghadimi, Reihaneh Mohammadi, Bobak Moazzami, Zinat Mohammadpour).

Background: Dietary modification is considered as one of the main strategies in the management of nonalcoholic fatty liver disease (NAFLD). The objective of this study was to systematically investigate the effect of dietary interventions on the cardio-metabolic risk factors, including lipid profile and insulin resistance in this population.

Methods: We searched electronic databases of PubMed and Scopus until January 2020 and included randomized controlled trials that compared the effect of dietary modifications vs. Read More

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February 2021

Cohort-based analysis of paternal opioid use in relation to offspring's BMI and plasma lipid profile.

Sci Rep 2021 May 4;11(1):9462. Epub 2021 May 4.

Non-Communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

A growing body of evidence suggests that opioid use may affect consumer's offspring by second-hand passive smoke exposure, as well as by transgenerational impacts mediated by genetic and epigenetic alterations of paternal gametes. In human studies, these effects are limited to investigating the neural, behavioral and cognitive characteristics of offspring. Only animal studies have investigated the metabolic parameters influenced by passive opium smoke exposure. Read More

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Distribution of waist-to-height ratio and cardiometabolic risk in children and adolescents: a population-based study.

Sci Rep 2021 May 4;11(1):9524. Epub 2021 May 4.

Department of Pediatrics, Kangdong Sacred Heart Hospital, Seoul, Republic of Korea.

This study was performed to evaluate the waist-to-height ratio (WHtR) distribution and assess its relationship with cardiometabolic risk in children and adolescents. A total of 8091 subjects aged 10-18 years were included from a nationally representative survey. Participants were classified into three groups: (1) < 85th, (2) ≥ 85th and < 95th, and (3) ≥ 95th percentile of WHtR. Read More

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Genetically-determined variations of are associated with antioxidant, muscular, and lipid biomarkers in response to Brazil nut consumption by patients using statins.

Br J Nutr 2021 May 5:1-21. Epub 2021 May 5.

Department of Health Sciences, Division of Nutrition and Metabolism, Ribeirão Preto Medical School, University of São Paulo - FMRP/USP, Brazil.

Several single nucleotide polymorphisms (SNPs) could indirectly, as well directly, influence metabolic parameters related to health effects in response to selenium (Se) supplementation. This study aimed to investigate whether the selenoprotein SNPs were associated with the response of Se status biomarkers to the Brazil nut consumption in patients using statins, and if the variation in Se homeostasis could affect antioxidant protection, lipid profile, muscle homeostasis, and selenoproteins mRNA. The study was performed in the Ribeirão Preto Medical School University Hospital. Read More

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Glycemic and lipid variability for predicting complications and mortality in diabetes mellitus using machine learning.

BMC Endocr Disord 2021 May 4;21(1):94. Epub 2021 May 4.

School of Life Sciences, Chinese University of Hong Kong, Hong Kong, China.

Introduction: Recent studies have reported that HbA1c and lipid variability is useful for risk stratification in diabetes mellitus. The present study evaluated the predictive value of the baseline, subsequent mean of at least three measurements and variability of HbA1c and lipids for adverse outcomes.

Methods: This retrospective cohort study consists of type 1 and type 2 diabetic patients who were prescribed insulin at outpatient clinics of Hong Kong public hospitals, from 1st January to 31st December 2009. Read More

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Feasibility and impact of laparoscopic sleeve gastrectomy after renal transplantation on comorbidities, graft function and quality of life.

BMC Surg 2021 May 4;21(1):235. Epub 2021 May 4.

Department of General Surgery, Faculty of Medicine, Benha University Hospital, Benha University, Benha, Egypt.

Background: The aim of this study is to clarify the feasibility and effect of laparoscopic sleeve gastrectomy (LSG) on comorbidities, graft function and quality of life in patients who underwent renal transplantation (RT).

Methods: This is a retrospective review of five patients who underwent LSG after RT. Demographic data, anthropometric parameters, the effect on comorbidities, postoperative course, immunosuppressive medications, causes of RT, renal function, the survival of graft, and quality of life after SG in obese patients with a history of RT were assessed using BAROS-Moorhead-Ardelt survey RESULTS: From September 2015 to September 2019, 5 renal transplant patients underwent LSG; three female, and two male. Read More

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Bee Bread Can Alleviate Lipid Abnormalities and Impaired Bone Morphology in Obese Zucker Diabetic Rats.

Molecules 2021 Apr 29;26(9). Epub 2021 Apr 29.

Department of Botany and Genetics, Faculty of Natural Sciences, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia.

This study examined for the first time whether bee bread (BB, consisting of monofloral rape bee pollen) could alleviate lipid derangements and reduced bone quality in Zucker diabetic fatty (ZDF) rats, which are considered an appropriate animal model for type 2 diabetes mellitus (T2DM) investigation. Adult ZDF rats were segregated into four groups: lean non-diabetic rats (L group), obese diabetic rats untreated (C group), and those treated with the BB at two doses (500 and 700 mg/kg body weight, respectively, B1 and B2 groups) for 10 weeks. Significantly reduced levels of total cholesterol and triglyceride were recorded in the B2 group versus the C group. Read More

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Impact of the Level of Adherence to Mediterranean Diet on the Parameters of Metabolic Syndrome: A Systematic Review and Meta-Analysis of Observational Studies.

Nutrients 2021 Apr 30;13(5). Epub 2021 Apr 30.

Laboratory of Hygiene, Social & Preventive Medicine and Medical Statistics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.

High adherence to the Mediterranean diet (MD) has been associated with a lower prevalence of Metabolic Syndrome (MetS). The present study aimed to investigate the impact of MD adherence on parameters of MetS. A systematic literature search was performed in PubMed, Cochrane Central Registry of Clinical Trials (CENTRAL), Scopus, EMBASE, Web of Science and Google Scholar databases. Read More

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Effects of Heat Stress on Gut-Microbial Metabolites, Gastrointestinal Peptides, Glycolipid Metabolism, and Performance of Broilers.

Animals (Basel) 2021 Apr 30;11(5). Epub 2021 Apr 30.

State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.

This paper investigated the effects of heat stress on gut-microbial metabolites, gastrointestinal peptides, glycolipid metabolism, and performance of broilers. Thus, 132 male Arbor Acres broilers, 28-days-old, were randomly distributed to undergo two treatments: thermoneutral control (TC, 21 °C) and high temperature (HT, 31 °C). The results showed that the average daily gain (ADG), average daily feed intake (ADFI), and gastric inhibitory polypeptide (GIP) concentration in the jejunum significantly decreased the core temperature, feed conversion ratio (FCR), and ghrelin of the hypothalamus, and cholecystokinin (CCK) in jejunum, and serum significantly increased in the HT group ( < 0. Read More

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Effect of Si-Miao-Yong-An decoction on the differentiation of monocytes, macrophages, and regulatory T cells in ApoE mice.

J Ethnopharmacol 2021 May 1:114178. Epub 2021 May 1.

Department of Cardiology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China. Electronic address:

Ethnopharmacological Relevance: Si-Miao-Yong-An decoction (SMYAD) is a renowned traditional Chinese medicinal formula. SMYAD was originally recorded in the "Shi Shi Mi Lu", which was edited by medical scientist Chen Shi'duo during the Qing Dynasty. SMYAD has been traditionally used to treat thromboangiitis obliterans. Read More

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Assessment of causal association between thyroid function and lipid metabolism: a Mendelian randomization study.

Chin Med J (Engl) 2021 Apr 13;134(9):1064-1069. Epub 2021 Apr 13.

Department of Cardiology, Peking University Third Hospital, Beijing 100191, China.

Background: Thyroid dysfunction is associated with cardiovascular diseases. However, the role of thyroid function in lipid metabolism remains partly unknown. The present study aimed to investigate the causal association between thyroid function and serum lipid metabolism via a genetic analysis termed Mendelian randomization (MR). Read More

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Antihyperlipidemic effect of tyrosol, a phenolic compound in streptozotocin-induced diabetic rats.

Toxicol Mech Methods 2021 May 4:1-34. Epub 2021 May 4.

Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar - 608002, Tamilnadu, India.

We investigated the antihyperlipidemic effects of tyrosol in streptozotocin (STZ)-induced diabetic rats. Rats were injected intraperitoneally with STZ (40 mg/kg), and these established experimental rats were treated with tyrosol (20 mg/kg) and glibenclamide (600µg/kg) for 45 days. The observed results revealed that tyrosol treatment significantly reduced plasma glucose, plasma, and liver total cholesterol, triglycerides, free fatty acids, phospholipids, plasma low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol, atherogenic index, and significantly increased plasma insulin and high-density lipoprotein cholesterol in STZ-induced diabetic rats. Read More

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Machine Learning Approaches to Identify Factors Associated with Women's Vasomotor Symptoms Using General Hospital Data.

J Korean Med Sci 2021 May 3;36(17):e122. Epub 2021 May 3.

Department of Obstetrics & Gynecology, Korea University College of Medicine, Seoul, Korea.

Background: To analyze the factors associated with women's vasomotor symptoms (VMS) using machine learning.

Methods: Data on 3,298 women, aged 40-80 years, who attended their general health check-up from January 2010 to December 2012 were obtained from Korea University Anam Hospital in Seoul, Korea. Five machine learning methods were applied and compared for the prediction of VMS, measured by the Menopause Rating Scale. Read More

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Study on the independent effect of thyroid hormone based on uric acid level on NAFLD.

J Health Popul Nutr 2021 May 3;40(1):21. Epub 2021 May 3.

Department of General Practice, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, 310016, China.

Objective: This study aims to explain the correlation among non-alcoholic fatty liver disease (NAFLD), hyperuricemia, and thyroid function and to find independent risk factors for each other.

Methods: Data were obtained from subjects who underwent health examination in the Health Promotion Centre of Sir Run Run Shaw Hospital of Zhejiang University from January 2017 to February 2019. The diagnosis of NAFLD was according to the clinical diagnosis of the guidelines. Read More

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Biomarkers of lipid metabolism in patients with juvenile idiopathic arthritis: relationship with disease subtype and inflammatory activity.

Pediatr Rheumatol Online J 2021 May 3;19(1):66. Epub 2021 May 3.

Department of Pediatrics, Universidade Federal de São Paulo, Rua Borges Lagoa, 802 - Vila Clementino, São Paulo, SP, CEP: 04038-001, Brazil.

Background: To describe the biomarkers of lipid metabolism in children and adolescents with polyarticular and systemic JIA and to relate them to diseases subtypes, diseases activity markers, and nutritional status.

Methods: A cross-sectional study including 62 JIA patients was performed. The following variables were evaluated: disease activity and medications used, body mass index, height for age (z-score), skin folds (bicipital, tricipital, subscapular and suprailiac), food intake based on three 24-h food recalls, lipid profile (total cholesterol (CT), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TG) and non-HDL (N-HDLc), glycemia and insulin, erythrocyte sedimentation rate (ESR), ultrasensitive C-reactive protein (us-CRP) and apolipoproteins A-I and B (Apo A-I and Apo B). Read More

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Health behaviors and metabolic risk factors are associated with dyslipidemia in ethnic Miao Chinese adults: the China multi-ethnic cohort study.

BMC Public Health 2021 May 3;21(1):851. Epub 2021 May 3.

School of Public Health, The Key Laboratory Of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, 550025, China.

Background: Cardiovascular risk factors in Chinese ethnic minority groups are rarely reported.

Objective: To quantify the cardiovascular risk factors in Miao Chinese adults and to examine the association of health behaviors and metabolic risk factors with dyslipidemia.

Methods: A cross-sectional analysis was conducted using baseline data from the China Multi-Ethnic Cohort (CMEC) study. Read More

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A Variant of Is Associated with the Risk and Blood Lipid Levels of Myocardial Infarction in Eastern Chinese Individuals.

Immunol Invest 2021 May 3:1-8. Epub 2021 May 3.

Department of Cardiology Surgery, The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huaian, China.

In this study, we determined to interpret the effects of the polymorphism on myocardial infarction (MI) risk. This study, conducted in a Chinese Han population, recruited 369 MI patients and 465 controls. The variant of gene ( polymorphism) was genotyped by PCR-RFLP method. Read More

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Comparative analysis of three nutrition scores in predicting mortality after acute myocardial infarction.

Nutrition 2021 Mar 17;90:111243. Epub 2021 Mar 17.

Department of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju, Republic of Korea. Electronic address:

Objective: We investigated the utility of nutrition scores in predicting mortality and prognostic importance of nutrition status using three different scoring systems in patients with acute myocardial infarction (AMI).

Methods: In total, 1147 patients with AMI were enrolled in this study (72.5 % men; mean age 65. Read More

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Associations of perfluorooctane sulfonate alternatives and serum lipids in Chinese adults.

Environ Int 2021 Apr 30;155:106596. Epub 2021 Apr 30.

Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. Electronic address:

Background: Chlorinated polyfluorinated ether sulfonic acids (Cl-PFESAs), a group of perfluorooctane sulfonate (PFOS) alternatives, can be widely observed in humans and environmental matrices. However, associations between exposure to Cl-PFESAs and serum lipid levels in adults are unknown.

Objective: To explore the relationships between Cl-PFESA levels and serum lipid levels in adults. Read More

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Association of cardiometabolic health factors with age-related executive function and episodic memory.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 2021 May 2:1-15. Epub 2021 May 2.

Department of Psychology, University of Miami, Coral Gables, United States.

Although decline of cognitive abilities in late life is regarded as a common facet of aging, there is inter-individual variability in this decline. Possible contributors are cardiometabolic risk factors associated with cerebrovascular dysfunction, but a dearth in unifying health-cognition models confound exactly how these risk factors mediate age-related changes in executive function (EF) and episodic memory. This study investigated the indirect effect of age on these cognitive abilities via cardiometabolic risk factors using a structural equation modeling approach. Read More

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Low-Density Lipoprotein Cholesterol 4: The Notable Risk Factor of Coronary Artery Disease Development.

Front Cardiovasc Med 2021 16;8:619386. Epub 2021 Apr 16.

Department of Cardiovascular Medicine, The First People's Hospital of Pingdingshan, Pingdingshan, China.

Coronary artery disease (CAD) is the leading cause of death worldwide, which has a long asymptomatic period of atherosclerosis. Thus, it is crucial to develop efficient strategies or biomarkers to assess the risk of CAD in asymptomatic individuals. A total of 356 consecutive CAD patients and 164 non-CAD controls diagnosed using coronary angiography were recruited. Read More

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Factorial Analysis of the Cardiometabolic Risk Influence on Redox Status Components in Adult Population.

Oxid Med Cell Longev 2021 27;2021:6661940. Epub 2021 Jan 27.

Department for Medical Biochemistry, University of Belgrade-Faculty of Pharmacy, Belgrade, Serbia.

Different byproducts of oxidative stress do not always lead to the same conclusion regarding its relationship with cardiometabolic risk, since controversial results are reported so far. The aim of the current study was to examine prooxidant determinant ((prooxidant-antioxidant balance (PAB)) and the marker of antioxidant defence capacity (total sulphydryl groups (tSHG)), as well as their ratio (PAB/tSHG) in relation to different cardiometabolic risk factors in the cohort of adult population. Additionally, we aimed to examine the joint effect of various cardiometabolic parameters on these markers, since to our knowledge, there are no studies that investigated that issue. Read More

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January 2021

Celastrol Attenuates Lipid Accumulation and Stemness of Clear Cell Renal Cell Carcinoma via CAV-1/LOX-1 Pathway.

Front Pharmacol 2021 16;12:658092. Epub 2021 Apr 16.

Division of Stem Cell Regulation and Application, Department of Pharmacology, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.

Clear cell renal cell carcinoma (ccRCC) is characterized by abnormal lipid accumulation. Celastrol is a pentacyclic triterpene extracted from Tripterygium wilfordii Hook F with anti-cancer activity. In the present study, the anticancer effects of celastrol on ccRCC and the underlying mechanisms were studied. Read More

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The Relationship Between Metabolic Parameters, Age, and Thyroid Status: A Cross-Sectional Study-Based National Survey of Iodine Nutrition, Thyroid Disease.

Risk Manag Healthc Policy 2021 23;14:1723-1730. Epub 2021 Apr 23.

Department of Rehabilitation, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, People's Republic of China.

Aim: The relationship between thyroid status and metabolic factors was investigated as well as iodine nutrition in the general population and among the elderly population.

Methods: We performed a cross-sectional survey of 2483 subjects to assess the status of national iodine nutrition and incidence of thyroid disease. The general and elderly populations were divided into normal thyroid function (NTF) and subclinical hypothyroidism (SCH) groups. Read More

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