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Ergonomics 2021 Apr 16:1-30. Epub 2021 Apr 16.

EuroMov Digital Health in Motion, Univ Montpellier, IMT Mines Ales, Montpellier, France.

Low-Altitude Flight (LAF) is a flight formation consisting of rapid close ground flight. Perception and control of self-motion, allowing for optimal information collection and rapid adaptation, are of fundamental importance during LAF, but remain largely unexplored. This study aimed to analyse the impact of visuo-vestibular stimuli on the monitoring of height in a motion-based simulated LAF context. Read More

HERD 2021 Apr 16:19375867211007941. Epub 2021 Apr 16.

Laboratory for Experimental Psychology, Faculty of Philosophy, 54801University of Belgrade, Serbia.

Aim: This article aims to make clearer, with supporting evidence, the clinical benefits of the nature-based rehabilitation program (NBRP) and the restorative values of visiting botanical garden for people with stress-related mental disorders.

Background: Throughout the years, nature-based therapy has been acknowledged as a valuable rehabilitation practice that integrates specially designed natural environments and nature-related activities for people with mental health conditions.

Subject And Methods: The comparative analyses of parallel conducted the NBRP at botanical garden and occupational therapy realised at the Day Hospital of the Institute of Mental Health in Belgrade included 27 participants divided into two groups. Read More

Interdiscip Sci 2021 Apr 8. Epub 2021 Apr 8.

School of Mathematics and Statistics, Xidian University, Xi'an, 710071, People's Republic of China.

DNA N6-methyladenine (6 mA), as an essential component of epigenetic modification, cannot be neglected in genetic regulation mechanism. The efficient and accurate prediction of 6 mA sites is beneficial to the development of biological genetics. Biochemical experimental methods are considered to be time-consuming and laborious. Read More

Brief Bioinform 2021 Apr 8. Epub 2021 Apr 8.

Department of Biological Science, Faculty of science, King Abdul-Aziz University, Jeddah-21589, Saudi Arabia.

Minichromosome maintenance complex component 7 (MCM7) belongs to the minichromosome maintenance family that is important for the initiation of eukaryotic DNA replication. Overexpression of the MCM7 protein is relative to cellular proliferation and responsible for aggressive malignancy in various cancers. Mechanistically, inhibition of MCM7 significantly reduces the cellular proliferation associated with cancer. Read More

Protein Sci 2021 Apr 7. Epub 2021 Apr 7.

Messiah University, Department of Chemistry and Biochemistry, One University Ave. Mechanicsburg, PA, USA.

Metal cofactors within proteins perform a versatile set of essential cellular functions. In order to take advantage of the diverse functionality of metalloproteins, researchers have been working to design or modify metal binding sites in proteins to rationally tune the function or activity of the metal cofactor. This study has performed an analysis on the backbone atom geometries of metal-binding amino acids among ten different metal binding sites within the entire protein data bank. Read More

BMC Bioinformatics 2021 Apr 7;22(1):179. Epub 2021 Apr 7.

Department of Biotechnology, Yeungnam University, Gyeongsan, 38541, Gyeongbuk, Korea.

Background: The rapid advances in next-generation sequencing technologies have revolutionized the microbiome research by greatly increasing our ability to understand diversity of microbes in a given sample. Over the past decade, several computational pipelines have been developed to efficiently process and annotate these microbiome data. However, most of these pipelines require an implementation of additional tools for downstream analyses as well as advanced programming skills. Read More

Med Phys 2021 Apr 7. Epub 2021 Apr 7.

College of Information and Computer, Taiyuan University of Technology, Taiyuan, China.

Pupose: The research is to improve the efficiency and accuracy of recognition of honeycomb lung in CT images.

Methods: Deep learning methods are used to achieve automatic recognition of honeycomb lung in CT images, however, is time consuming and less accurate due to the large amount of structural parameters. In this paper, a novel recognition method based on MobileNetV1 network, multi-scale feature fusion method (MSFF) and dilated convolution are explored to deal with honeycomb lung in CT images classification. Read More

IEEE Trans Pattern Anal Mach Intell 2021 Apr 7;PP. Epub 2021 Apr 7.

Neural Architecture Search (NAS) has emerged as a promising technique for automatic neural network design. However, existing MCTS based NAS approaches often utilize manually designed action space, which is not directly related to the performance metric to be optimized (e.g. Read More

Int J Inj Contr Saf Promot 2021 Apr 6:1-12. Epub 2021 Apr 6.

RBG Lab, Department of Engineering Design, IIT Madras, Chennai, India.

Single-vehicle crashes are of major concern in both developed as well as in Low Middle Income Countries due to the severity of injuries, particularly fatal accidents. In India, a significant proportion of crashes are single-vehicle crashes. The vehicles which are involved in accidents due to causes such as self skidding, hitting stationary objects, trees that are simply contributed by the drivers themselves are referred to as out-of-control single-vehicle crashes. Read More

Arch Razi Inst 2021 Mar 1;76(1):31-39. Epub 2021 Mar 1.

Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.

Newcastle disease is a highly contagious viral infection affecting many species of birds that can spread fast between poultry houses and cause a heavy economic burden on the poultry industry all around the world. Fusion and hemagglutinin-neuraminidase (HN) protein are important in the pathogenesis of the Newcastle disease virus (NDV). The HN protein is a critical viral protein with multiple functions and plays a key role in the formation of the virulence of NDV. Read More

Cancers (Basel) 2021 Mar 23;13(6). Epub 2021 Mar 23.

Department of Sociology, Social Work and Public Health, Faculty of Labour Sciences, University of Huelva, 21007 Huelva, Spain.

Night work has been highlighted by the International Agency for Research on Cancer (IARC) as a likely carcinogenic factor for humans, associated with breast cancer and professions that require continuity of work. Knowing the impact that short and long-term night work has on the nurses' collective seems a priority, therefore, this study aims to analyse the relationship between night work and the development of breast cancer risk factors in nurses. For this, a cross-sectional study through an online questionnaire on breast cancer risk variables and working life was designed. Read More

IEEE Trans Image Process 2021 12;30:4198-4211. Epub 2021 Apr 12.

In this paper, we aim to address issues of (1) joint spatial-temporal modeling and (2) side information injection for deep-learning based in-loop filter. For (1), we design a deep network with both progressive rethinking and collaborative learning mechanisms to improve quality of the reconstructed intra-frames and inter-frames, respectively. For intra coding, a Progressive Rethinking Network (PRN) is designed to simulate the human decision mechanism for effective spatial modeling. Read More

Antonie Van Leeuwenhoek 2021 Apr 2. Epub 2021 Apr 2.

School of Natural and Environmental Sciences, Newcastle University, Ridley Building 2, Newcastle upon Tyne, NE1 7RU, UK.

A polyphasic study was designed to determine the taxonomic provenance of a strain, isolate PRKS01-29, recovered from an Indonesian sand dune and provisionally assigned to the Streptomyces violaceusniger clade. Genomic, genotypic and phenotypic data confirmed this classification. The isolate formed an extensively branched substrate mycelium which carried aerial hyphae that differentiated into spiral chains of rugose ornamented spores, contained LL-as the wall diaminopimelic acid, MK-9 (H, H) as predominant isoprenologues, phosphatidylethanolamine as the diagnostic phospholipid and major proportions of saturated, iso- and anteiso- fatty acids. Read More

Hosp Pharm 2021 Apr 9;56(2):102-108. Epub 2019 Aug 9.

Faculty of Pharmacy Lebanese University, Hadath, Lebanon.

In a hospitalized setting, malnutrition is known to increase patient's mortality and lower the quality of life; therefore, it is essential to detect such cases and intervene at the earliest possible. The goal of this study is to estimate the rate of malnutrition in hospitalized Lebanese patients, explore its association with different factors, and create a simple tool to detect patients at high risk of malnutrition. One hundred and fifty Lebanese hospitalized patients, suffering at least from one chronic disease, were randomly chosen from Centre Hospitalier Universitaire Notre Dame de Secours (CHU-NDS) hospital. Read More

Sci Rep 2021 Mar 31;11(1):7291. Epub 2021 Mar 31.

Institute of Automation, Chinese Academy of Sciences, Beijing, China.

The study of cellular complexity in the nervous system based on anatomy has shown more practical and objective advantages in morphology than other perspectives on molecular, physiological, and evolutionary aspects. However, morphology-based neuron type classification in the whole rat brain is challenging, given the significant number of neuron types, limited reconstructed neuron samples, and diverse data formats. Here, we report that different types of deep neural network modules may well process different kinds of features and that the integration of these submodules will show power on the representation and classification of neuron types. Read More

Environ Int 2021 Mar 27;153:106529. Epub 2021 Mar 27.

Department of Geography, University of Sheffield, S102TN, United Kingdom. Electronic address:

High levels of arsenic in drinking water and food materials continue to pose a global health challenge. Over 127 million people alone in Bangladesh (BD) and West Bengal (WB) state of India are exposed to elevated levels of arsenic in drinking water. Despite decades of research and outreach, arsenic awareness in communities continue to be low. Read More

Eur J Obstet Gynecol Reprod Biol 2021 Mar 15;260:124-130. Epub 2021 Mar 15.

Mater Research, The University of Queensland, Queensland, Australia; University of Queensland, School of Medicine, Queensland, Australia; Mater Mothers Hospitals, Queensland, Australia.

Objective: The aim of this work was to assess the cost-effectiveness of induction of labor with outpatient balloon catheter cervical priming versus inpatient prostaglandin vaginal gel or tape.

Study Design: Economic evaluation alongside a multi-centre, randomized controlled trial at eight Australian maternity hospitals. The trial reported on 448 women with live singleton term pregnancies, undergoing induction of labor for low-risk indications between September 2015 and October 2018. Read More

Int J Phytoremediation 2021 Mar 25:1-11. Epub 2021 Mar 25.

Department of Environmental Sciences and Engineering, Government College University, Faisalabad, Pakistan.

Soil reclamation through afforestation along with soil amendments is one of the most suitable practices to combat soil salinity while the use of biochar may have potential to ameliorate salt-affected soils. This study was designed to check effects of different biochars on the physico-chemical properties of soil and characteristics of three important agroforestry trees species: , in saline soils. Farmyard manure biochar (FYMB), sugarcane bagasse biochar (SCB), woodchips biochar (WCB) were applied (6% w/w) to check their effects on plants under saline conditions. Read More

J Comput Chem 2021 Mar 25. Epub 2021 Mar 25.

Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany.

The full configuration interaction (FCI) method is only applicable to small molecules with few electrons in moderate size basis sets. One of the main alternatives to obtain approximate FCI energies for bigger molecules and larger basis sets is selected CI. However, due to: (a) the lack of a well-defined structure in a selected CI Hamiltonian, (b) the potentially large number of electrons together with c) potentially large orbital spaces, a computationally and memory efficient algorithm is difficult to construct. Read More

Front Genet 2021 8;12:632232. Epub 2021 Mar 8.

Guangdong Yunfu Vocational College of Chinese Medicine, Yunfu, China.

Edible bird's nest (EBN) is a popular delicacy in the Asian Pacific region originating from Indonesia, Malaysia, Thailand and Vietnam, which consist of various potential medicine value in Traditional Chinese Medicine (TCM). Thailand is one of the main exporters of EBN. However, the genetic information of EBN, a key part of molecular biology, has yet to be reported in Thailand. Read More

Eur Urol Focus 2021 Mar 21. Epub 2021 Mar 21.

Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria; Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia; Division of Urology, Department of Special Surgery, Jordan University Hospital, The University of Jordan, Amman, Jordan; Karl Landsteiner Institute of Urology and Andrology, Vienna, Austria; Department of Urology, Weill Cornell Medical College, New York, NY, USA; Department of Urology, University of Texas Southwestern, Dallas, TX, USA; Department of Urology, Second Faculty of Medicine, Charles University, Prague, Czech Republic. Electronic address:

Context: Patients with intermediate-risk non-muscle-invasive bladder cancer (NMIBC) may pose a clinical dilemma without an agreed evidence-based decision tree for personalized treatment.

Objective: To perform a systematic review and network meta-analysis (NMA) to summarize available evidence on the oncologic outcomes of intravesical therapy in patients with intermediate-risk NMIBC.

Evidence Acquisition: The MEDLINE, EMBASE, and ClinicalTrials. Read More

Mol Biol Rep 2021 Mar 23. Epub 2021 Mar 23.

School of Agricultural Sciences, Zhengzhou University, Zhengzhou, 450001, China.

Taiwania cryptomerioides Hayata is an endangered relict tree species which is endemic to mainland China, Taiwan, Myanmar, and northern Vietnam. It is an economically important tree species and has been used for reforestation in mountain areas of mainland China and Taiwan. In order to investigate its genetic diversity for conservation and restoration, we developed and characterized 15 nuclear microsatellite markers based on next-generation sequencing data. Read More

BMC Bioinformatics 2021 Mar 22;22(1):138. Epub 2021 Mar 22.

Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 197 Ruijin Er Road, Shanghai, 200025, China.

Background: The rapidly increasing dimensionality and throughput of flow and mass cytometry data necessitate new bioinformatics tools for analysis and interpretation, and the recently emerging single-cell-based algorithms provide a powerful strategy to meet this challenge.

Results: Here, we present CytoTree, an R/Bioconductor package designed to analyze and interpret multidimensional flow and mass cytometry data. CytoTree provides multiple computational functionalities that integrate most of the commonly used techniques in unsupervised clustering and dimensionality reduction and, more importantly, support the construction of a tree-shaped trajectory based on the minimum spanning tree algorithm. Read More

IEEE Trans Cybern 2021 Mar 22;PP. Epub 2021 Mar 22.

This article aims to establish an appointed-time observer-based framework to efficiently address the resilient consensus control problem of linear multiagent systems with malicious attacks. The local appointed-time state observer is skillfully designed for each agent to estimate the agent's actual state value at the appointed time, even in the presence of unknown malicious attacks. Based on the state estimation, a new kind of resilient control strategy is proposed, where a virtual system is constructed for each agent to generate an ideal state value such that the consensus of normal agents can be achieved with the exchange of ideal state values among neighboring agents. Read More

New Phytol 2021 Mar 19. Epub 2021 Mar 19.

Center of Excellence Global Change Ecology, Department of Biology, University of Antwerp, Universiteitsplein 1, Wilrijk, 2610, Belgium.

Tree stems and soils can act as sources and sinks for the greenhouse gases (GHG) carbon dioxide (CO ), methane (CH ), and nitrous oxide (N O). Since both uptake and emission capacities can be large, especially in tropical rainforests, accurate assessments of the magnitudes and temporal variations of stem and soil GHG fluxes are required. We designed a new flexible stem chamber system for continuously measuring GHG fluxes in a French Guianese rainforest. Read More

Front Artif Intell 2021 18;4:591529. Epub 2021 Feb 18.

Department of Mathematical Sciences, University of Arkansas, Fayetteville, AR, United States.

Early detection of community health risk factors such as stress is of great interest to health policymakers, but representative data collection is often expensive and time-consuming. It is important to investigate the use of alternative means of data collection such as crowdsourcing platforms. An online sample of Amazon Mechanical Turk (MTurk) workers (N = 500) filled out, for themselves and their child, demographic information and the 10-item Perceived Stress Scale (PSS-10), designed to measure the degree to which situations in one's life are appraised as stressful. Read More

Saudi J Biol Sci 2021 Mar 28;28(3):1548-1556. Epub 2020 Dec 28.

Department of Botany & Microbiology College of Science King, Saud University P.O Box 2455, Riyadh 11451, Saudi Arabia.

Various viruses can infect honey bees, but deformed wing virus (DWV) is considered the most dangerous virus to them and has role in the sudden decline of bee colonies. This virus has different strains; however, there are no available studies to compare the characteristics of these strains utilizing bioinformatics. In this study, 27 strains of deformed wing virus were analyzed based on their sequences and their genetic relationships. Read More

SAR QSAR Environ Res 2021 Apr 18;32(4):317-331. Epub 2021 Mar 18.

School of Science, Xi'an Polytechnic University, Xi'an, P. R. China.

DNA replication is not only the basis of biological inheritance but also the most fundamental process in all living organisms. It plays a crucial role in the cell-division cycle and gene expression regulation. Hence, the accurate identification of the origin of replication sites (ORIs) has a great meaning for further understanding the regulatory mechanism of gene expression and treating genic diseases. Read More

J Prim Care Community Health 2021 Jan-Dec;12:21501327211000213

Pfizer SAS, Bogotá, Colombia.

Objectives: To assess budget impact of the implementation of an anticoagulation clinic (AC) compared to usual care (UC), in patients with non-valvular atrial fibrillation (NVAF).

Method: A decision tree was designed to analyze the cost and events rates over a 1-year horizon. The patients were distributed according to treatment, 30% Direct Oral Anticoagulant (DOAC) regimens and the rest to warfarin. Read More

Indian J Hematol Blood Transfus 2021 Jan 2;37(1):126-133. Epub 2020 Nov 2.

Department of Blood Transfusion, Chinese PLA General Hospital, No. 28, Fuxing Rd, Beijing, 100853 China.

It is difficult to predict RBC consumption accurately. This paper aims to use big data to establish a XGBoost Model to understand the trend of RBC accurately, and forecast the demand in time. XGBoost, which implements machine learning algorithms under the Gradient Boosting framework can provide a parallel tree boosting. Read More