6 results match your criteria treatment 11ka

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Androgens During the Reproductive Years: What Is Normal for Women?

J Clin Endocrinol Metab 2019 11;104(11):5382-5392

Women's Health Research Program, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

Objective: Whether serum androgen levels can identify women with "androgen insufficiency" or "androgen excess" is unresolved; thus, what constitutes "normal" remains uncertain. We sought to determine whether androgens, including 11-oxygenated C19 steroids, vary with age, menstrual cycle, or body mass index (BMI), during the reproductive years.

Design And Setting: Cross-sectional study recruited from eastern Australian states. Read More

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November 2019

Effects of androgens on the leptin system in immature male Atlantic salmon parr.

Gen Comp Endocrinol 2018 02 19;257:122-129. Epub 2017 Aug 19.

Department of Organismal Biology, Comparative Physiology, Evolutionary Biology Centre, Uppsala University, SE-752 36 Uppsala, Sweden. Electronic address:

Leptin modulates all levels of the reproductive endocrine axis in mammals, and in turn, both leptin and the leptin receptor are regulated by sex steroids. The aim of this study was to investigate if sex steroids regulate the leptin system also in fish. Immature one-year old male Atlantic salmon parr were implanted with Silclear capsules that were either empty or filled with 11-ketoandrostenedione (11KA) or testosterone (T) and the effects of 35-days treatment were investigated on measures of maturation, gene expression of leptin (lepa1, lepa2), leptin receptor (lepra1) and circulating plasma leptin. Read More

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February 2018

Effects of castration and androgen-treatment on the expression of FSH-beta and LH-beta in the three-spine stickleback, gasterosteus aculeatus--feedback differences mediating the photoperiodic maturation response?

Gen Comp Endocrinol 2008 Sep 18;158(2):178-82. Epub 2008 Jul 18.

Department of Zoology, Stockholm University, S-106 91 Stockholm, Sweden.

In many animals, including the three-spine stickleback (Gasterosteus aculeatus), photoperiod strongly influences reproduction. The aim of this study was to investigate if feedback mechanisms on the brain-pituitary-gonadal axis play a role in mediating the photoperiodic response in the stickleback. To that end, stickleback males, exposed to either non-stimulatory short photoperiod (light/dark 8:16) or under stimulatory long photoperiod (LD 16:8), were subjected to either sham-operation, castration, castration combined with treatment with the androgens 11-ketoandrostenedione (11KA) and testosterone (T), and the effects on levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH)-beta mRNA were analyzed. Read More

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September 2008

Androgen and behavior in the male three-spined stickleback, Gasterosteus aculeatus. II. Castration and 11-ketoandrostenedione effects on courtship and parental care during the nesting cycle.

Horm Behav 2002 Nov;42(3):337-44

Department of Zoology, Stockholm University, S-106 91, Stockholm, Sweden.

Courtship declines and ceases while parental care increases in the presence of developing eggs during the nesting cycle of the male three-spined stickleback, Gasterosteus aculeatus. Furthermore, circulating 11-ketotestosterone (11KT) levels are higher during the initial "courtship phase" than during the later "parental phase," similar to that found in other paternal fishes. This study aimed to investigate a possible functional relationship between changes in 11KT levels and changes in reproductive behavior during the nesting cycle. Read More

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November 2002

Feedback control of gonadotropins in Atlantic salmon, Salmo salar, male parr.II. Aromatase inhibitor and androgen effects.

Gen Comp Endocrinol 1999 Apr;114(1):142-50

Department of Zoology, University of Stockholm, Stockholm, S-106 91,

Both positive and negative feedback on the (hypothalmus)- pituitary-gonad axis occur in salmonids. The aim of the present study was to investigate the role of different androgens, and in particular the involvement of aromatization of androgens to estrogens in feedback mechanisms. Previously mature Atlantic salmon, Salmo salar, male parr were studied in two experiments. Read More

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Effects of gonadectomy and steroids on plasma and pituitary levels of somatolactin in Atlantic salmon, Salmo salar.

Gen Comp Endocrinol 1998 Feb;109(2):223-31

Department of Zoology, Stockholm University, Sweden.

Somatolactin (SL) is a hormone recently isolated and characterized from fish pituitaries. Although the functions of SL are still largely unknown, it has been implicated in reproduction. In this study, the effects of gonadal steroids on SL secretion were investigated in Atlantic salmon male parr in two experiments. Read More

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February 1998
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