51,169 results match your criteria treatment items

Protective Role of 360° Laser Retinopexy in Patients with Rhegmatogenous Retinal Detachment: a Systematic Review and Meta-analysis.

Korean J Ophthalmol 2021 Jun 4;35(3):215-222. Epub 2021 Jun 4.

Department of Ophthalmology, University of Texas Health at San Antonio, San Antonio, TX, USA.

Purpose: Visual impairment from retinal re-detachment could be debilitating. The aim of this review is to evaluate the role of 360° laser retinopexy on success rate of rhegmatogenous retinal detachment (RRD) repair by a meta-analysis study.

Methods: The PubMed, Scopus, and the Cochrane Library databases were searched comprehensively from the date of database inception to January 2021, evaluating the role of 360° laser retinopexy in visual and anatomical success rate of RRD repair. Read More

View Article and Full-Text PDF

Development and initial validation of the nonalcoholic fatty liver disease self-management questionnaire.

Res Nurs Health 2021 Jun 13. Epub 2021 Jun 13.

College of Medicine, Department of Internal Medicine and Institute of Gastroenterology, Yonsei University, Seoul, Republic of Korea.

The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing, and self-management is essential to improve health outcomes in this population. Despite the importance of self-management, there is no instrument to assess it in patients with NAFLD. The purpose of this study was to develop and validate an initial version of a self-management questionnaire for patients with NAFLD. Read More

View Article and Full-Text PDF

Development of a physical function outcome measure to harmonize comparisons between three Asian adult populations.

Qual Life Res 2021 Jun 12. Epub 2021 Jun 12.

Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, Texas, 77555, USA.

Purpose: The purpose of this study was to use modern measurement techniques and create a precise functional status metric for Asian adults.

Methods: The study subjects included Asian American adults from the 2012 Health and Retirement Study (n = 211), Chinese adults in the China Health and Retirement Longitudinal Study (n = 13,649), and Korean adults in the Korean Longitudinal Study of Aging (n = 7,486). The Rasch common-item equating method with nine self-care and mobility items from the three databases were used to create a physical function measure across the three Asian adult populations. Read More

View Article and Full-Text PDF

Fear Avoidance Beliefs Are Associated with Perceived Disability in Persons with Vestibular Disorders.

Phys Ther 2021 Jun 12. Epub 2021 Jun 12.

Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA.

Objective: The purpose of this study was to determine the association between fear-avoidance beliefs and disability in 3 months in people with vestibular disorders while accounting for demographic and clinical characteristics.

Methods: This prospective cohort study included people aged 18 to 100 years who reported dizziness. Participants were recruited from a balance disorders clinic and outpatient physical therapy clinics. Read More

View Article and Full-Text PDF

Opinions about coronavirus vaccination – the role of healthcare workers in communication in December 2020

Orv Hetil 2021 06 13;162(24):931-937. Epub 2021 Jun 13.

2 Károli Gáspár Református Egyetem, Bölcsészet- és Társadalomtudományi Kar, Pszichológiai Intézet, Személyiség- és Egészségpszichológiai Tanszék, Budapest.

Összefoglaló. Bevezetés: A koronavírus elleni védőoltással kapcsolatos vélekedések igen aktuális, társadalmi szempontból fontos területét adják az egészségmagatartással foglalkozó kutatásoknak. Célkitűzés: Vizsgálatunk a védőoltásról különbözőképpen vélekedő (oltást elutasító, oltást választó, oltáson nem gondolkodó, valamint bizonytalan) csoportok elemzését tűzte ki célul az oltás előnyeinek és hátrányainak, valamint az információforrások használatának tekintetében. Read More

View Article and Full-Text PDF

Transcranial photobiomodulation in the management of brain disorders.

J Photochem Photobiol B 2021 May 5;221:112207. Epub 2021 May 5.

ENT and Head & Neck Research Center, The Five Senses Health eInstitute, Iran University of Medical Sciences (IUMS), Tehran, Iran. Electronic address:

Transcranial photobiomodulation (tPBM) is the process of delivering light photons through the skull to benefit from its modifying effect. Brain disorders are important health problems. The aim of this review was to determine the existing evidence of effectiveness, useful parameters, and safety of tPBM in the management of traumatic brain injury, stroke, Parkinson, and Alzheimer's disease as the common brain disorders. Read More

View Article and Full-Text PDF

Radioimmunotherapy of glioblastoma multiforme - Current status and future prospects.

Crit Rev Oncol Hematol 2021 Jun 10;163:103395. Epub 2021 Jun 10.

Cancer Research Institute, University of South Australia, Adelaide, SA, 5001, Australia; Department of Physics, University of Adelaide, Adelaide, SA, 5005, Australia. Electronic address:

Glioblastoma multiforme (GBM) or grade IV astrocytoma is the most diagnosed form of primary brain tumours in adults. Radioimmunotherapy (RIT), mostly in combination with conventional therapies, is presented in the current review as a therapeutic strategy of high potential in the management of GBM. A systematic literature search was performed following the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) to identify clinical studies that employed a form of radioimmunotherapy using alpha- or beta-emitting radioisotopes. Read More

View Article and Full-Text PDF

The Functional Assessment of Cancer Therapy Eight Dimension (FACT-8D), a Multi-Attribute Utility Instrument Derived From the Cancer-Specific FACT-General (FACT-G) Quality of Life Questionnaire: Development and Australian Value Set.

Value Health 2021 Jun 7;24(6):862-873. Epub 2021 May 7.

Northwestern University Feinberg School of Medicine, Department of Medical Social Sciences, Chicago, IL, USA.

Objectives: To develop a cancer-specific multi-attribute utility instrument derived from the Functional Assessment of Cancer Therapy - General (FACT-G) health-related quality of life (HRQL) questionnaire.

Methods: We derived a descriptive system based on a subset of the 27-item FACT-G. Item selection was informed by psychometric analyses of existing FACT-G data (n = 6912) and by patient input (n = 82). Read More

View Article and Full-Text PDF

Recommendations for planning and delivery of radical radiotherapy for localized urothelial carcinoma of the bladder.

Radiother Oncol 2021 Jun 9. Epub 2021 Jun 9.

Department of Radiotherapy, Institut Bergonié, Bordeaux, France. Electronic address:

Purpose: Curative radio-chemotherapy is recognized as a standard treatment option for muscle-invasive bladder cancer (MIBC). Nevertheless, the technical aspects for MIBC radiotherapy are heterogeneous with a lack of practical recommendations.

Methods And Materials: In 2018, a workshop identified the need for two cooperative groups to develop consistent, evidence-based guidelines for irradiation technique in the delivery of curative radiotherapy. Read More

View Article and Full-Text PDF

A comprehensive assessment of genetic variation in serotonin transporter gene (5-HTTLPR+rs25531) and the response to dapoxetine in Chinese patients with premature ejaculation.

Andrologia 2021 Jun 12:e14141. Epub 2021 Jun 12.

Department of Urology, First Affiliated Hospital of Anhui Medical University, Hefei, China.

This study was to explore whether serotonin transporter gene-linked polymorphic region polymorphisms (5-HTTLPR+rs25531) influence the response to dapoxetine treatment in a Chinese population with premature ejaculation (PE). 112 patients with PE re-enrolled from our previous study received dapoxetine monotherapy. At the endpoint, patients with S'S' had a significant increased risk of nonresponse compared with L' carriers (p < . Read More

View Article and Full-Text PDF

Assessment of Dermal and Inhalation Exposure to Permethrin During Field Treatment of Military Uniforms.

Mil Med 2021 Jun 12. Epub 2021 Jun 12.

Preventive Medicine and Biostatistics Department, USUHS Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

Introduction: Permethrin is a common pesticide spray-applied to civilian clothing and military uniforms for protection against biting arthropods in an effort to reduce risks to arthropod-borne diseases. During mass clothing spray events, exposure is possible through the dermal, inhalation, and ingestion routes. The potentially exposed population during a spray event includes the pesticide applicator(s) and working party (personnel who handle clothing/uniforms by positioning on the ground, flipping, and removing after spraying is complete). Read More

View Article and Full-Text PDF

Screening for more with less: Validation of the Global Appraisal of Individual Needs Quick v3 (GAIN-Q3) screeners.

J Subst Abuse Treat 2021 Jul 15;126:108414. Epub 2021 Apr 15.

Suzanne Dworak-Peck School of Social Work, USC Center for Artificial Intelligence in Society, USC Center for Mindfulness Science, USC Institute for Addiction Science, University of Southern California, United States of America.

Multi-morbidity is the norm among adolescents and adults with substance use and other mental disorders and warrants a multi-pronged screening approach. However, the time constraints on assessment inherent in clinical practice often temper the desire for a full understanding of multi-morbidity problems. The 15- to 25-minute Global Appraisal of Individual Needs Quick version 3 (GAIN-Q3) includes screeners for 9 common clinical problems that are short (4 to 10 items) and provide dimensional measures of problem severity in each area that are also categorized to guide clinical decision making. Read More

View Article and Full-Text PDF

Physiotherapists' perspectives on barriers to implementation of direct access of physiotherapy services in the United Arab Emirates: A cross-sectional study.

PLoS One 2021 11;16(6):e0253155. Epub 2021 Jun 11.

Department of Physiotherapy, College of Health sciences, University of Sharjah, Sharjah, UAE.

Background: There are two primary ways of accessing physiotherapy for service users around the world. The direct access, as opposed to the indirect access which requires a referral from a general physician, has several merits including better quality, timeliness, cost effectiveness of treatment and better probability of preventing acute conditions from turning into chronic ailments. Despite these benefits, several countries including the UAE, do not allow direct access to physiotherapists. Read More

View Article and Full-Text PDF

Inter-rater reliability and predictive accuracy of the Shkuratova Assessment of Falls-risk in Rehabilitation (SAFER) tool.

Int J Rehabil Res 2021 Jun 10. Epub 2021 Jun 10.

Peninsula Health, The Mornington Center Deakin University Geelong, Centre for Quality and Patient Safety Research-Epworth HealthCare Partnership, Melbourne Deakin University Geelong, School of Nursing and Midwifery, Victoria Deakin University Geelong, Centre for Quality and Patient Safety Research-Monash Health Partnership, Monash Health, Clayton, Melbourne, Australia.

Despite the recognised importance of falls prevention in rehabilitation settings, there is limited research focusing on falls risk assessment tools designed to guide both patient screening and therapy. This study evaluated the predictive accuracy and inter-rater reliability of the Shkuratova Assessment of Falls-risk in Rehabilitation settings (SAFER) tool. The study was conducted at a subacute rehabilitation facility in Australia. Read More

View Article and Full-Text PDF

Development and Validation of a Patient-Reported Outcome Measure of Ataxia.

Mov Disord 2021 Jun 11. Epub 2021 Jun 11.

Global Health Outcomes and Epidemiology, Biohaven Pharmaceuticals, New Haven, Connecticut, USA.

Background: Assessment of cerebellar ataxia has been confined to rating scales, gait laboratories, and wearable sensors agnostic to patient input.

Objectives: The objective of this study was to develop a Patient-Reported Outcome Measure of Ataxia.

Methods: (1) The conceptual framework, item pool development, and domain selection were developed using online surveys completed by 147 ataxia patients. Read More

View Article and Full-Text PDF

The active feedback program: bringing medical students out of the shadows.

Med Educ Online 2021 Dec;26(1):1939842

Department of Neurology, Georgetown University, Washington, DC, USA.

Despite many advances in medical education, medical students continue to mostly shadow on inpatient rotations like Neurology. They seldom receive face-to-face feedback or mentorship from attending physicians. This results from not training attending physicians how to integrate medical students into clinical activities in a way that does not detract from patient rounds. Read More

View Article and Full-Text PDF
December 2021

Upper airway cough syndrome may be the main cause of chronic cough in Japan: a cohort study.

Kimihiko Yasuda

Fam Pract 2021 Jun 11. Epub 2021 Jun 11.

Yasuda Clinic, Internal Medicine, 2-2-20-2F, Takasago, Urawa-ku, Saitama-shi, Saitama, 330-0063, Japan.

Background: Upper airway cough syndrome (UACS) is generally considered a common cause of chronic cough but remains poorly recognised in Japan.

Objective: This study aimed to assess whether UACS was a common cause of chronic cough in Japan, as is true in other countries. Interview and examination items were evaluated for their potential use in UACS diagnosis. Read More

View Article and Full-Text PDF

Identifying Patterns of Failure and Risk Factors for Recurrence in Patients of Paratesticular Sarcomas: Protocol of a Systematic Review and Meta-Analysis.

Int J Surg Protoc 2021 May 28;25(1):84-91. Epub 2021 May 28.

Department of Radiotherapy, All India Institute of Medical Sciences, New Delhi, IN.

Introduction: Para testicular sarcomas are rare mesenchymal tumors that affect patients of all ages. Unlike other sites of sarcoma, they tend to be of lower grade and have a higher propensity for lymphatic spread. Management is hampered by the small number of patients who differ in terms of tumor grade and histology. Read More

View Article and Full-Text PDF

Subarachnoid Hemorrhage in Mechanical Thrombectomy for Acute Ischemic Stroke: Analysis of the STRATIS Registry, Systematic Review, and Meta-Analysis.

Front Neurol 2021 25;12:663058. Epub 2021 May 25.

Division of Neuroradiology, Joint Department of Medical Imaging, Toronto Western Hospital, Toronto, ON, Canada.

The indications for mechanical thrombectomy in acute ischemic stroke continue to broaden, leading neurointerventionalists to treat vessel occlusions at increasingly distal locations farther in time from stroke onset. Accessing these smaller vessels raises the concern of iatrogenic subarachnoid hemorrhage (SAH) owing to increasing complexity in device navigation and retrieval. This study aims to determine the prevalence of SAH following mechanical thrombectomy, associated predictors, and resulting functional outcomes using a multicenter registry and compare this with a systematic review and meta-analysis of the literature. Read More

View Article and Full-Text PDF

The Effect of Viloxazine Extended-Release Capsules on Functional Impairments Associated with Attention-Deficit/Hyperactivity Disorder (ADHD) in Children and Adolescents in Four Phase 3 Placebo-Controlled Trials.

Neuropsychiatr Dis Treat 2021 3;17:1751-1762. Epub 2021 Jun 3.

Supernus Pharmaceuticals, Inc., Rockville, MD, USA.

Purpose: The ADHD Rating Scale (ADHD-RS) assesses 18 symptoms of inattention and hyperactivity/impulsivity and has been used in many clinical trials to evaluate the treatment effect of drugs on ADHD. The fifth edition of this scale (ADHD-RS-5) also assesses the impact of inattention and hyperactivity/impulsivity symptoms on six domains of functional impairment (FI): family relationships, peer relationships, completing/returning homework, academic performance at school, controlling behavior at school, and self-esteem. Here, we report the effect of viloxazine extended-release capsules (viloxazine ER), a novel nonstimulant treatment for ADHD in children and adolescents (ages 6-17 years), on FI from a post hoc analysis of four randomized, double-blind, placebo-controlled Phase 3 clinical trials (N=1354). Read More

View Article and Full-Text PDF

Arthroscopic bankart repair for the management of anterior shoulder instability: Mid- and long-term results.

Rev Esp Cir Ortop Traumatol 2021 Jul-Aug;65(4):255-263

Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain.

Introduction: Arthroscopic stabilisation is a well-recognised surgical technique with a variable rate of failure reported between 0-35%. The aim of this study was to evaluate the outcome of this technique and our second aim was to identify risk factors that could be associated to recurrence rate.

Material And Methods: 41 patients that underwent arthroscopic shoulder stabilisation for glenohumeral instability between 2001-2015 were included. Read More

View Article and Full-Text PDF

A meta-analysis of the efficacy and safety of adjuvant sorafenib for hepatocellular carcinoma after resection.

World J Surg Oncol 2021 Jun 10;19(1):168. Epub 2021 Jun 10.

Department of Oncology, The Second Affiliated Hospital of Nanchang University, No. 1, Minde Road, Nanchang, 330006, Jiangxi Province, People's Republic of China.

Background: Sorafenib was reported as a useful adjuvant treatment in patients with hepatocellular carcinoma who underwent surgical resection. However, its therapeutic value remains controversial. This meta-analysis examined the available data regarding the efficacy and safety of sorafenib in patients with hepatocellular carcinoma after radical surgery. Read More

View Article and Full-Text PDF

The Current Evidence for Factors that Influence Treatment Decision-Making in Localised Kidney Cancer: A Mixed Methods Systematic Review.

J Urol 2021 Jun 11:101097JU0000000000001901. Epub 2021 Jun 11.

Translational Oncology and Urology Research, King's College London, London, UK.

Introduction: With a growing number of treatment options for localised kidney cancer, patients and health care professionals have both the opportunity and the burden of selecting the most suitable management option. This mixed method systematic review aims to understand the barriers and facilitators of the treatment decision-making process in localised kidney cancer.

Methods: We searched PubMed, Embase, and Cochrane Central databases between first of January 2004 and 23rd of April 2020 using the JBI Manual for Evidence Synthesis and the Preferred Reporting Items for Systematic Review and Meta-analysis statement. Read More

View Article and Full-Text PDF

Stress management interventions among socioeconomically disadvantaged parents: A meta-analysis and moderation analysis.

Int J Nurs Stud 2021 Apr 24;120:103954. Epub 2021 Apr 24.

Michigan State University College of Nursing, 1355 Bogue St., C241, East Lansing, MI 48824, United States. Electronic address:

Background: Socioeconomically disadvantaged parents experience high levels of stress, anxiety, and depression. Many interventions have been tested to reduce parental stress, but no meta-analysis has been conducted to quantitatively summarize the effects and explore the moderators of intervention effects among socioeconomically disadvantaged parents.

Objective: This meta-analysis aimed to (1) quantitatively examine the intervention effects of prior stress management interventions among socioeconomically disadvantaged parents on reducing stress, depression, and anxiety; and (2) explore the potential moderators of intervention effects. Read More

View Article and Full-Text PDF

Using machine learning to improve the discriminative power of the FERD screener in classifying patients with schizophrenia and healthy adults.

J Affect Disord 2021 Jun 1;292:102-107. Epub 2021 Jun 1.

School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan;; Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan;; Department of Occupational Therapy, College of Medical and Health Science, Asia University, Taichung, Taiwan.. Electronic address:

Background Facial emotion recognition deficit (FERD) seems to be an obvious feature of patients with schizophrenia and has great potential for classifying patients and non-patients. The FERD screener was previously developed to classify patients from healthy adults. However, an obvious drawback of this screener is that the recommended cut-off scores could enhance either sensitivity or specificity (about 0. Read More

View Article and Full-Text PDF

Cost-effectiveness of precision diagnostic testing for precision medicine approaches against non-small-cell lung cancer: a systematic review.

Mol Oncol 2021 Jun 10. Epub 2021 Jun 10.

Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, United Kingdom.

Precision diagnostic testing (PDT) employs appropriate biomarkers to identify cancer patients that may optimally respond to precision medicine (PM) approaches, such as treatments with targeted agents and immuno-oncology drugs. To date, there are no published systematic appraisals evaluating the cost effectiveness of PDT in non-small-cell lung cancer (NSCLC). In order to address this gap, we conducted Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) searches for the years 2009-2019. Read More

View Article and Full-Text PDF

Economic burden of age-related macular degeneration in routine clinical practice: the RAMDEBURS study.

Int Ophthalmol 2021 Jun 10. Epub 2021 Jun 10.

University and Polytechnic Hospital of La Fé, Valencia, Spain.

Purpose: To describe and evaluate the main direct health costs, in routine clinical practice, of age-related macular degeneration (AMD) patients, from hospital perspective, in Spain.

Methods: Retrospective, multicenter, and observational study conducted on five third-level Spanish hospitals, between December 2018 and December 2019. The study included patients who were diagnosed of AMD before December 2018. Read More

View Article and Full-Text PDF

Economic evaluation of ivabradine in treatment of patients with heart failure: A systematic review.

Expert Rev Pharmacoecon Outcomes Res 2021 Jun 10. Epub 2021 Jun 10.

Department of Public Health, Faculty of Health, Ilam University of Medical Sciences, Ilam, Iran.

Background: Chronic heart failure (CHF) is a clinical status and a progressive health disorder extremely related to increased morbidity and mortality worldwide. Accordingly, this study aimed to assess systematic review of literature on cost-effectiveness done in patients with heart failure receiving Ivabradine plus standard treatment compared with standard treatment alone.

Areas Covered: This study is a systematic review in which all published articles related to the study topic were assessed in time range of 2014 to 2020. Read More

View Article and Full-Text PDF

Radiofrequency thermoablation (RFA) and radiotherapy (RT) combined treatment for bone metastases: a systematic review.

Eur Rev Med Pharmacol Sci 2021 May;25(10):3647-3654

Villa Santa Teresa, Radioterapia Oncologica, Bagheria, Palermo, Italy.

Objective: Approximately 50% of cancer patients develop bone metastases in their natural disease history. The management of metastatic bone disease requires a multidisciplinary approach. Both radiofrequency ablation (RFA) and radiation therapy (RT) were safe and effective in the management of painful metastases, even if they rely on totally different action mechanisms. Read More

View Article and Full-Text PDF

Validation and Psychometric Properties of the Persian Version of the 21-Item Game Addiction Scale With a Sample of Adolescents and Young Adults.

Front Psychiatry 2021 24;12:649276. Epub 2021 May 24.

Substance Abuse Prevention Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Excessive gaming has become a psychological health issue for both gamers and their social environments. This observation holds true for western but also non-western countries such as Iran. The aim of the present study was to translate and validate a Persian version of the Game Addiction Scale 21 (GAS 21) using a sample of adolescents and adults. Read More

View Article and Full-Text PDF