1,264 results match your criteria transvaginal primary


Conservative cesarean scar pregnancy treatment: local methotrexate injection followed by hysteroscopic removal with hysteroscopic tissue removal system.

Fertil Steril 2021 Jul 18. Epub 2021 Jul 18.

Division of Gynecology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Objective: To describe a conservative cesarean scar pregnancy (CSP) treatment in a patient with the desire for future pregnancy. To date, there is no gold standard for the management of a viable CSP. There is a wide range of treatment options that include major surgery and minimally invasive procedures. Read More

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Estimated Performance of Transvaginal Ultrasonography for Evaluation of Postmenopausal Bleeding in a Simulated Cohort of Black and White Women in the US.

JAMA Oncol 2021 Jul 15. Epub 2021 Jul 15.

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill.

Importance: Black women in the US with endometrial cancer (EC) are more likely to be diagnosed with advanced-stage disease independent of insured status and histologic type. The most common way of diagnosing EC at early stages is through screening of people with postmenopausal bleeding to detect endometrial thickness (ET). This approach may disproportionately underperform in Black women secondary to a higher prevalence of fibroids and nonendometrioid EC in this population, both of which affect the quality of ET measurement. Read More

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Long-term outcomes of primary cystocele repair by transvaginal mesh surgery versus laparoscopic mesh sacropexy: extended follow-up of the PROSPERE multicentre randomised trial.

BJOG 2021 Jul 15. Epub 2021 Jul 15.

Centre Hospitalier de Dunkerque, 59760, Dunkerque, France.

Objective: To compare the effectiveness and safety of Laparoscopic Sacropexy (LS) and Transvaginal mesh (TVM) at four years.

Design: Extended follow-up of a randomised trial.

Setting: 11 centres POPULATION: Women with cystocele stage ≥ 2 (POP-Q), aged 45 to 75 years without previous prolapse surgery. Read More

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Contribution of ultrasonography to the prediction of the induction-delivery interval: The ECOLDIA prospective multicenter cohort study.

J Gynecol Obstet Hum Reprod 2021 Jul 10;50(10):102196. Epub 2021 Jul 10.

Department of Gynecology and Obstetrics, Centre Hospitalier Régional Universitaire Tours, Tours, France.

Introduction: To evaluate the ability of preinduction ultrasonographic cervical length to predict the interval between induction and delivery in women at term with a Bishop score of 4 to 6 at induction.

Study Design: This multicenter prospective observational cohort recruited 334 women from April 2010 to March 2014. Inclusion criteria were women with singleton pregnancies at a gestational age ≥37 weeks, with no previous caesarean, a medical indication for induction of labor, and a Bishop score of 4, 5, or 6. Read More

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Transvaginal hydrolaparoscopy versus hysterosalpingography in the work-up for subfertility: a randomized controlled trial.

Reprod Biomed Online 2021 May 2. Epub 2021 May 2.

Department of Obstetrics and Gynecology, Maxima Medical Center, 5500 MB Veldhoven, the Netherlands.

Research Question: Is transvaginal hydrolaparoscopy (THL) non-inferior to hysterosalpingography (HSG) as a first-line tubal patency test in subfertile women in predicting the chance of conception leading to live birth?

Design: A multicentre, randomized controlled trial in four teaching hospitals in the Netherlands, which randomized subfertile women scheduled for tubal patency testing to either THL or HSG as a first-line tubal patency test. The primary outcome was conception leading to live birth within 24 months after randomization.

Results: A total of 149 women were randomized to THL and 151 to HSG. Read More

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Comparison of Transvaginal and Transumbilical Laparoscopic Single-Site Surgery for Ovarian Cysts.

JSLS 2021 Apr-Jun;25(2)

Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA.

Background: Minimally invasive surgery is currently a preferred treatment for symptomatic ovarian cyst(s), with single-site techniques, such as transumbilical laparoendoscopic single-site surgery (TU-LESS) and transvaginal laparoendoscopic single-site surgery (TV-LESS), gaining increasing popularity. Although both methods have delivered positive outcomes, there is currently limited literature directly comparing TU-LESS and TV-LESS.

Objectives: This study had two primary objectives: (1) to evaluate the safety and feasibility of TV-LESS and TU-LESS for the treatment of ovarian cysts and (2) to compare the surgical and postoperative outcomes of the two procedures. Read More

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Diagnostic criteria for retained products of conception - a scoping review.

Acta Obstet Gynecol Scand 2021 Jul 10. Epub 2021 Jul 10.

Department of Gynecology and Reproductive Medicine, University Medical Centre Utrecht, Utrecht, the Netherlands.

Introduction: Numerous studies have been performed assessing optimal treatment regimens for evacuating (retained) products of conception from the uterus, but standardised criteria for diagnosing retained products of conception (RPOC) are still lacking. We aim to provide an overview of diagnostic criteria in current literature, used to diagnose RPOC after induced first-trimester abortion or early pregnancy loss.

Material And Methods: Pubmed, EMBASE, and the Cochrane library were searched systematically up until March 2020 for English articles reporting on induced abortion or early pregnancy loss. Read More

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Peritoneal lesions caused by suspected to be metastases of ovarian malignancy.

BMJ Case Rep 2021 Jul 8;14(7). Epub 2021 Jul 8.

Microbiology, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.

, also known as pinworm, is a helminth that commonly causes intestinal parasitic infestation. can also cause extraintestinal infestations. We report a case of lower abdominal pain and intermittent vaginal bleeding in a 45-year-old woman who was referred to our gynaecology department. Read More

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Vaginally Assisted Laparoscopic Urethrolysis and Mesh Excision after Tension-free Vaginal Tape.

J Minim Invasive Gynecol 2021 Jul 3. Epub 2021 Jul 3.

Department of Obstetrics and Gynecology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey (all authors).

Study Objective: To present technique of vaginally assisted laparoscopic urethrolysis and mesh excision after tension-free vaginal tape.

Design: Demonstration video.

Setting: Despite the Food and Drug Administration's warning to limit the use of mesh, midurethral sling surgery (MUS) has not significantly decreased, but operations for complications have increased 3 times [1]. Read More

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Evaluation of a strategy for difficult embryo transfers from a prospective series of 2,046 transfers.

F S Rep 2021 Mar 9;2(1):43-49. Epub 2020 Dec 9.

Centre de Fertilité - Groupe Hospitalier Diaconesses Croix Saint Simon, Paris, France.

Objective: To evaluate an embryo transfer strategy for difficult transfers (DiTs).

Design: Prospective, nonrandomized, observational, cohort study.

Setting: A hospital fertility center in France. Read More

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Transvaginal two-dimensional ultrasound measurement of cervical volume to predict the outcome of the induction of labour: a prospective observational study.

BMC Pregnancy Childbirth 2021 Jun 22;21(1):433. Epub 2021 Jun 22.

North Colombo Teaching Hospital, Ragama, Sri Lanka.

Background: Assessing the likelihood of success of induction of labour using ultrasonically measured cervical volume is an important research question.

Method: A prospective observational study was carried out at North Colombo Teaching Hospital, Ragama, Sri Lanka. Pre-induction digital cervical assessment, transvaginal cervical length, and cervical volume measurements were performed. Read More

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A new technique for uterine incision closure at the time of cesarean section: does it make a difference?

J Obstet Gynaecol 2021 Jun 22:1-8. Epub 2021 Jun 22.

Department of Obstetrics and Gynecology, Faculty of Medicine, Menoufia University, Shibin Elkom, Egypt.

The purpose of this study was to compare the short-term operative outcomes of three different surgical techniques for uterine incision closure during caesarean section (CS). This trial enrolled 120 patients scheduled for primary caesarean delivery. Patients were randomised into either classical double-layer uterine closure, purse-string double-layer uterine closure (Turan), or our new approach of uterine closure (double layer step up-step down technique). Read More

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Evaluation of surgical approaches for vesicovaginal fistulae repair: the case for transvaginal repair as the gold standard.

Int Urogynecol J 2021 Jun 11. Epub 2021 Jun 11.

Division of Urology, Department of Surgery, Southern Alberta Institute of Urology, University of Calgary, Calgary, Alberta, Canada.

Introduction And Hypothesis: To highlight the success rates of two approaches of transvaginal vs. transabdominal closures for the vesicovaginal fistula (VVF) repair and to investigate the patient, fistula, and surgical factors relevant to surgical characteristics and successful outcomes.

Methods: Retrospective analysis of 66 consecutive patients who underwent VVF repair between 2005 and 2020. Read More

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Transperineal pelvic floor ultrasound for analyzing the outcomes of pelvic floor surgery for the treatment of anterior compartment prolapse: A comparative study of transvaginal mesh and native-tissue repair.

Low Urin Tract Symptoms 2021 Jun 8. Epub 2021 Jun 8.

Department of Medical Ultrasound, Shanghai Tenth People's Hospital, Ultrasound Research and Education Institute, Tongji University Cancer Center, Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment, Tongji University School of Medicine, Shanghai, China.

Objective: To compare the outcomes of transvaginal mesh (TVM) and native-tissue repair (NTR) for the repair of anterior compartment prolapse.

Methods: This retrospective study involved 90 patients with anterior compartment prolapse who underwent pelvic organ prolapse surgery between January 2018 and October 2020. A TVM was used to treat 53 patients and 37 underwent NTR. Read More

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Direct access from general practice to transvaginal ultrasound for early detection of ovarian cancer: a feasibility study.

Scand J Prim Health Care 2021 Jun 7;39(2):230-239. Epub 2021 Jun 7.

Department of Public Health, Aarhus University, Aarhus, Denmark.

Objective: To investigate the feasibility of providing general practitioners (GPs) direct and fast referral access to transvaginal ultrasound (TVUS).

Design: A prospective cohort study.

Setting: A total of 232 Danish general practices in parts of the Central Denmark Region. Read More

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Defining mechanisms of recurrence following apical prolapse repair based on imaging criteria.

Am J Obstet Gynecol 2021 Jun 1. Epub 2021 Jun 1.

Biostatistics and Epidemiology Division, RTI International, Research Triangle Park, NC.

Background: Prolapse recurrence after transvaginal surgical repair is common; however, its mechanisms are ill-defined. A thorough understanding of how and why prolapse repairs fail is needed to address their high rate of anatomic recurrence and to develop novel therapies to overcome defined deficiencies.

Objective: This study aimed to identify mechanisms and contributors of anatomic recurrence after vaginal hysterectomy with uterosacral ligament suspension (native tissue repair) vs transvaginal mesh (VM) hysteropexy surgery for uterovaginal prolapse. Read More

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Transvaginal Ultrasound-Guided Core Biopsy-Experiences in a Comprehensive Cancer Centre.

Cancers (Basel) 2021 May 25;13(11). Epub 2021 May 25.

Department of Gynaecology, National Institute of Oncology, 1122 Budapest, Hungary.

In this paper, we report our experience of transvaginal ultrasound (TVUS)-guided core biopsies involving 303 patients referred to the gynaecological ultrasound unit of our national comprehensive cancer centre. Adequate histologic specimens were obtained in 299 patients (98.7%). Read More

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Surgical Outcomes of Hysterectomy via Robot-assisted versus Traditional Transvaginal Natural Orifice Transluminal Endoscopic Surgery.

J Minim Invasive Gynecol 2021 May 24. Epub 2021 May 24.

Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas (all authors). Electronic address:

Study Objective: To evaluate the safety and feasibility of robot-assisted transvaginal natural orifice transluminal endoscopic surgery (R-vNOTES) hysterectomy when compared with traditional vNOTES (T-vNOTES) hysterectomy.

Design: Retrospective chart review.

Setting: Academic tertiary setting. Read More

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The Spiral Trial: A multicenter, randomized, controlled trial of Spiral thread sutures versus conventional thread sutures to prevent thinning of uterine scars following elective cesarean section.

Contemp Clin Trials 2021 May 20;107:106449. Epub 2021 May 20.

Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan.

Background: The aim of this randomized controlled trial (RCT) is to investigate whether Spiral-thread sutures are superior to conventional sutures (0-Vicryl) for preventing uterine scar thinning following elective cesarean section.

Methods: This multicenter, parallel-group RCT will be conducted in four hospitals across three medical regions in Japan to assess 200 women (≥20 years old) with singleton pregnancies who are scheduled to undergo cesarean sections. Eligible women will be randomly assigned (1:1 ratio) to receive either the conventional uterine suture continuous absorption thread, which is most commonly used in Japan, or the Spiral thread. Read More

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Uterine involvement by endometriosis: Sonographic features from elusive findings to apparent adenomyosis.

Eur J Obstet Gynecol Reprod Biol 2021 Jul 9;262:93-98. Epub 2021 May 9.

Department of Obstetrics and Gynecology, Akdeniz University School of Medicine, 07059, Antalya, Turkey.

Objective: The primary aim of this study is to investigate whether there are any minor sonographic uterine findings, not typical for adenomyosis, in endometriosis patients. The secondary objective is to determine the prevalence of sonographic features of adenomyosis in an infertile population with endometriosis.

Study Design: The investigation was of 291 infertile women with endometriosis, either manifesting endometrioma (OMA) or diagnosed through laparoscopy, who were investigated for two-dimensional transvaginal sonographic (2D-TVS) features of adenomyosis. Read More

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Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial.

Lancet 2021 06 12;397(10290):2182-2193. Epub 2021 May 12.

MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK.

Background: Ovarian cancer continues to have a poor prognosis with the majority of women diagnosed with advanced disease. Therefore, we undertook the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) to determine if population screening can reduce deaths due to the disease. We report on ovarian cancer mortality after long-term follow-up in UKCTOCS. Read More

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Added value of contrast-enhanced ultrasound (CEUS) in the diagnosis of primary retroperitoneal serous adenocarcinoma: a case report.

BMC Med Imaging 2021 May 12;21(1):80. Epub 2021 May 12.

Department of Ultrasound Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People's Republic of China.

Background: Primary retroperitoneal serous adenocarcinoma (PRSA) is a rare malignant disease. Given the rarity of the disease, the imaging features of PRSA are unclear. Contrast-enhanced ultrasound (CEUS) also plays an important role in the evaluation of the differential diagnosis of retroperitoneal lesions. Read More

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Can sonographic changes in cervical length during pregnancy predict the need for cervical ripening in term pregnancies?

Arch Gynecol Obstet 2021 May 12. Epub 2021 May 12.

Department of Obstetrics and Gynecology, Meir Medical Center, Tchernichovsky 59, 44281, Kfar Saba, Israel.

Purpose: To evaluate the effect of changes in sonographic cervical length (CL) measured at 14-16 and 21-24 weeks of gestation, on cervical ripening in term pregnancies.

Methods: This retrospective, cohort study included term pregnancies with CL measured with transvaginal sonography (CL at 14-16 weeks gestation and CL at 21-24 weeks). History of preterm labor, multiple gestations, planned caesarean section, fetal anomalies and stillbirths were excluded. Read More

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Low-Grade Appendiceal Mucinous Neoplasm (LAMN) Primarily Diagnosed as an Ovarian Mucinous Tumor.

Case Rep Surg 2021 22;2021:5523736. Epub 2021 Apr 22.

Department of Surgery, University Hospital of Larissa, Greece.

Background: Low-grade appendiceal mucinous neoplasms (LAMN) are detected in 0.7 to 1.7% of all appendicectomies. Read More

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Assessing the Pregnancy Protective Impact of Scheduled Nonadherence to a Novel Progestin-Only Pill: Protocol for a Prospective, Multicenter, Randomized, Crossover Study.

JMIR Res Protoc 2021 Jun 8;10(6):e29208. Epub 2021 Jun 8.

Centre for Reproductive Health, University of Edinburgh, Edinburgh, United Kingdom.

Background: Progestin-only contraceptive pills (POP) are commonly reserved for women with medical comorbidities but in actuality, POPs can be safely used by anyone wanting to prevent pregnancy. This wide safety profile makes them an ideal candidate for being available over the counter without a prescription, but adherence issues may be more common with over-the-counter use. We need a better understanding of the ability of POPs to prevent pregnancy when adherence issues occur in the form of a missed or delayed pill. Read More

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Prediction of labour onset in women who present with symptoms of preterm labour using cervical length.

BMC Pregnancy Childbirth 2021 May 5;21(1):359. Epub 2021 May 5.

Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, Singapore, Singapore.

Background: Diagnosis of preterm labour is difficult because initial symptoms and signs are often mild and may occur in continuing pregnancies. This study aims to investigate the utility of measuring cervical length, using transvaginal ultrasound, in women presenting to the delivery suite with symptoms of preterm labour.

Methods: This was a prospective cohort study performed in KK Women's and Children's Hospital, Singapore from September 2017 to July 2018. Read More

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Transvaginal primary layered repair of postsurgical urethrovaginal fistula.

Int Urogynecol J 2021 Jul 5;32(7):1941-1943. Epub 2021 May 5.

ASST Monza, Ospedale San Gerardo, via G.B. Pergolesi, 33 20900, Monza, Italy.

Introduction And Hypothesis: Urethrovaginal fistula (UVF) is a rare disorder, which implies the presence of an abnormal communication between the urethra and the vagina.

Methods: Surgical repair options include transurethral, transabdominal and transvaginal procedures, either with or without tissue interposition. The vaginal route is considered a safe and effective option to correct UVF. Read More

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Midtrimester Cervical Length in Low-Risk Nulliparous Women for the Prediction of Spontaneous Preterm Birth: Should We Consider a New Definition of Short Cervix?

Am J Perinatol 2021 May 3. Epub 2021 May 3.

Research Center, CHU de Québec-Université Laval, Québec, Canada.

Objective:  The study aimed to estimate the predictive value of midtrimester cervical length (CL) and the optimal cut-off of CL that should be applied with asymptomatic nulliparous women for the prediction of spontaneous preterm birth (sPTB).

Study Design:  This is a prospective cohort study of asymptomatic nulliparous women with a singleton gestation. Participants underwent CL measurement by transvaginal ultrasound between 20 and 24 weeks of gestation. Read More

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Reducing day 3 baseline monitoring bloodwork and ultrasound for patients undergoing timed intercourse and intrauterine insemination treatment cycles.

Fertil Res Pract 2021 Apr 30;7(1):11. Epub 2021 Apr 30.

Department of Obstetrics and Gynaecology, University of Toronto, 123 Edward Street, Suite 1200, Toronto, ON, M5G 1E2, Canada.

Background: In the current context of a global pandemic it is imperative for fertility clinics to consider the necessity of individual tests and eliminate those that have limited utility and may impose unnecessary risk of exposure. The purpose of this study was to implement and evaluate a multi-modal quality improvement (QI) strategy to promote resource stewardship by reducing routine day 3 (d3) bloodwork and transvaginal ultrasound (TVUS) for patients undergoing intrauterine insemination (IUI) and timed intercourse (IC) treatment cycles.

Methods: After literature review, clinic stakeholders at an academic fertility centre met to discuss d3 testing utility and factors contributing to d3 bloodwork/TVUS in IC/IUI treatment cycles. Read More

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A Phase I Clinical Trial to Assess Safety and Tolerability of Injectable Collagenase in Women with Symptomatic Uterine Fibroids.

Reprod Sci 2021 Apr 29. Epub 2021 Apr 29.

Department of Gynecology and Obstetrics, Division of Reproductive Sciences & Women's Health Research, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Research Building, Room 624, Baltimore, MD, 21205, USA.

Uterine fibroids feature excessive deposition of types I and III collagen. Previous ex vivo studies showed an FDA-approved collagenase (EN3835)-digested types I and III collagen fibers in fibroid tissues; however, collagenase had not been evaluated in vivo for effects on uterine fibroids. The objective was to assess the safety and tolerability of collagenase injection directly into uterine fibroids. Read More

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