16,842 results match your criteria transit time

Fast calculation method of transient temperature rise of motor for electro-mechanical braking.

Sci Prog 2021 Apr-Jun;104(2):368504211024553

School of Mechanical and Energy Engineering, Tongji University, Shanghai, China.

Electro-mechanical braking is a new braking mode of rail vehicles, which has the advantages of compact structure, fast response speed, and high precision. It is a new braking technology that conforms to the development trend of full electrification and full intelligence of rail transit brake devices. Due to the special power demand of the electro-mechanical braking device, the electro-mechanical braking motor has a short-time and intermittent working mechanism and is in the state of blocking during working, resulting in its high-temperature rise. Read More

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Colonic Transit Time and Fecal Impaction in Children and Adolescents with Cystic Fibrosis-Associated Constipation.

J Pediatr Gastroenterol Nutr 2021 Jun 11. Epub 2021 Jun 11.

Discipline of Pediatric Gastroenterology, Pediatric Department, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil, Rua dos Otonis, 839, São Paulo - SP, Brazil, CEP 04025-002 Discipline of Pediatric Specialties, Division of Pediatric Pneumology, Pediatric Department, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil, Rua Borges Lagoa, 760, São Paulo, SP, Brazil, CEP 04038-002.

Background: Constipation is prevalent in pediatric cystic fibrosis patients and colonic motility has not been studied in this population. In this study, we aimed to evaluate the total and segmental colonic transit time in children and adolescents with cystic fibrosis based on the presence of constipation and radiological fecal impaction.

Methods: In this case series, all patients aged 3 to 20 years of a cystic fibrosis reference center were invited to participate. Read More

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Transit Time Measurement in Indicator Dilution Curves: Overcoming the Missing Ground Truth and Quantifying the Error.

Front Physiol 2021 28;12:588120. Epub 2021 May 28.

Institute of Biomedical Engineering, Karlsruhe Institute of Technology, Karlsruhe, Germany.

The vascular function of a vessel can be qualitatively and intraoperatively checked by recording the blood dynamics inside the vessel via fluorescence angiography (FA). Although FA is the state of the art in proving the existence of blood flow during interventions such as bypass surgery, it still lacks a quantitative blood flow measurement that could decrease the recurrence rate and postsurgical mortality. Previous approaches show that the measured flow has a significant deviation compared to the gold standard reference (ultrasonic flow meter). Read More

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Predatory activity of nematophagus fungus in infective larvae after gastrointestinal transit: biological control in pasture areas and .

J Helminthol 2021 Jun 14;95:e31. Epub 2021 Jun 14.

Programa de Pós-graduação em Zootecnia, Departamento de Zootecnia, Universidade Federal do Paraná, Curitiba, 80035-050, Paraná, Brazil.

Biological control is a strategy to decrease parasitic populations, and the action takes place through natural antagonists in the environment. We studied the predatory activity of the fungus Duddingtonia flagrans in infective larvae (L3) of gastrointestinal nematodes after gastrointestinal transit. Ten heifers were divided into two groups: treated (animals received pellets containing fungus) and control (animals received pellets without fungus). Read More

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Simultaneous evaluation of perfusion and morphology using GRASP MRI in hepatic fibrosis.

Eur Radiol 2021 Jun 12. Epub 2021 Jun 12.

Surgery, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 03087, Republic of Korea.

Objectives: To determine if golden-angle radial sparse parallel (GRASP) dynamic contrast-enhanced (DCE)-MRI allows simultaneous evaluation of perfusion and morphology in liver fibrosis.

Methods: Participants who were scheduled for liver biopsy or resection were enrolled (NCT02480972). Images were reconstructed at 12-s temporal resolution for morphologic assessment and at 3. Read More

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Spore-forming Bacillus coagulans SNZ 1969 improved intestinal motility and constipation perception mediated by microbial alterations in healthy adults with mild intermittent constipation: A randomized controlled trial.

Food Res Int 2021 Aug 19;146:110428. Epub 2021 May 19.

Department of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Republic of Korea; Department of Nutritional Science and Food Management, Graduate Program in System Health Science and Engineering, Ewha Womans University, Seoul 03760, Republic of Korea. Electronic address:

The spore-forming Bacillus coagulans has attracted attention for their therapeutic action in the colon. However, the mechanism of this action remains unclear. In this study, healthy subjects with mild intermittent constipation were supplemented with B. Read More

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Population Pharmacokinetics of Oral Levofloxacin in Healthy Volunteers and Dosing Optimization for Multidrug-resistant Tuberculosis Therapy.

Biopharm Drug Dispos 2021 Jun 11. Epub 2021 Jun 11.

Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkla, 90110, Thailand.

Background: Levofloxacin is considered to be a key component of multidrug-resistant tuberculosis (MDR-TB) regimen. However, there is considerable concern regarding the subtherapeutic concentrations of currently used doses and the development of drug resistance.Therefore, this study aimed to describe the population pharmacokinetics of oral levofloxacin in healthy volunteers and to evaluate the probability of target attainment (PTA) in an attempt to optimize the dosing regimens for MDR-TB therapy. Read More

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Fast Response Organic Tandem Photodetector for Visible and Near-Infrared Digital Optical Communications.

Small 2021 Jun 10:e2101316. Epub 2021 Jun 10.

State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, 2699 Qianjin Street, Changchun, 130012, P. R. China.

Organic photodetectors (OPDs), which usually work as photodiodes, photoconductors, or phototransistors, have emerged as candidates for next-generation light sensing. However, low response speed caused by low carrier mobility and resistance-capacitance (RC) time constant, severely hinders the commercialization of OPDs. Herein, the authors demonstrate a state-of-the-art OPD with a record response speed of 146. Read More

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Management of COVID-19 in a Deployed Setting.

Mil Med 2021 Jun 11. Epub 2021 Jun 11.

US Army Institute of Surgical Research, San Antonio, TX 78234, USA.

Introduction: Hamid Karzai International Airport is a NATO military base connected to the international airport in Kabul, Afghanistan. It is one of the larger NATO installations in Afghanistan, and with its location being one of the main hubs for international transit, the base has been at the frontline since the beginning of the COVID-19 pandemic. Hamid Karzai International Airport base commanders and medical staff have been at the forefront, continually developing policies and procedures to mitigate the pandemic in a deployed setting. Read More

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The Value of Susceptibility-Weighted Imaging (SWI) in Evaluating the Ischemic Penumbra of Patients with Acute Cerebral Ischemic Stroke.

Neuropsychiatr Dis Treat 2021 3;17:1745-1750. Epub 2021 Jun 3.

Department of Radiology, Chinese Medical Hospital of Yiwu, Yiwu, 322000, People's Republic of China.

Background: The aim of this study was to discuss the value of susceptibility-weighted imaging (SWI) in evaluating the ischemic penumbra of patients with acute cerebral ischemic stroke.

Methods: Data were collected from 52 patients with acute cerebral ischemic stroke upon clinical diagnosis and routine examinations of magnetic resonance imaging (MRI), including SWI, diffusion-weighted imaging (DWI), and perfusion-weighted imaging (PWI) within 72 hours after onset in this retrospective study. The methods also included fusing the DWI and SWI images and calculating the volume of anomaly extension of DWI and PWI-MTT (mean transit time) using semi-automatic analysis software. Read More

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[Application of optimized catheter management strategy in interhospital patients transition with extracorporeal membrane oxygenation].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2021 May;33(5):600-604

Department of Emergency, Second Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi, China. Corresponding author: Wu Jiehua, Email:

Objective: To discuss the effect of optimized catheter management strategy on reducing the incidence of catheter-related adverse events in interhospital patients transition with extracorporeal membrane oxygenation (ECMO).

Methods: A historical control trial was conducted. The patients transferred with ECMO to the Second Affiliated Hospital of Nanchang University from January 2018 to December 2020 were enrolled. Read More

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Use of health care services among Syrian refugees migrating to Norway: a prospective longitudinal study.

BMC Health Serv Res 2021 Jun 10;21(1):572. Epub 2021 Jun 10.

Department of Global Public Health and Primary Care, University of Bergen, PO Box 7804, 5020, Bergen, Norway.

Background: Understanding the differential utilization of healthcare services is essential to address the public health challenges. Through the migration process, refugees move from one set of health risk factors to another and can face multiple healthcare challenges along their journey. Yet how these changing risk factors influence refugees' use of health care services is poorly understood. Read More

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High-resolution time-of-flight PET detector with 100 ps coincidence time resolution using a side-coupled phoswich configuration.

Phys Med Biol 2021 Jun 9;66(12). Epub 2021 Jun 9.

Department of Radiology, Molecular Imaging Program at Stanford, School of Medicine, Stanford University, CA, United States of America.

Photon time-of-flight (TOF) capability in positron emission tomography (PET) enables reconstructed image signal-to-noise ratio (SNR) improvement. With the coincidence time resolution (CTR) of 100 picosecond (ps), a five-fold SNR improvement can be achieved with a 40 cm diameter imaging subject, relative to a system without TOF capability. This 100 ps CTR can be achieved for adetector design (crystal element length ≥20 mm with reasonably high crystal packing fraction) using a side-readout PET detector configuration that enables 511 keV photon interaction depth-independent light collection efficiency and lower variance in scintillation photon transit time to the silicon photomultiplier (SiPM). Read More

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Renal cortical transit time in the evaluation of prenatally detected presumed pelvi ureteric junction like obstruction: A systematic review.

Indian J Urol 2021 Apr-Jun;37(2):116-124. Epub 2021 Apr 1.

Department of Radiology, Chitale Clinic Pvt. Ltd Solapur, Maharashtra, India.

Introduction: Differentiating nonobstructive from obstructive dilatation of the kidney is a clinical dilemma in prenatally detected hydronephrosis. Many radionuclide renogram parameters have been used to differentiate obstructed from non-obstructed units, including cortical transit time (CTT). We evaluate the role of CTT in identifying obstruction through a systematic review. Read More

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BOLD Lag Patterns Differ Between Rest And Task Conditions, But Are Largely Typical in Autism.

Brain Connect 2021 Jun 9. Epub 2021 Jun 9.

San Diego State University, 7117, Brain Development Imaging Laboratories, San Diego, California, United States;

Autism spectrum disorder (ASD) is characterized by atypical functional connectivity (FC) within and between distributed brain networks. However, FC findings have often been inconsistent, possibly due to focus on static FC rather than brain dynamics. Lagged connectivity analyses aim to evaluate temporal latency, and presumably neural propagation, between regions. Read More

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Clinical characteristics and therapy response in unresectable melanoma patients stage IIIB-IIID with in-transit and satellite metastases.

Eur J Cancer 2021 Jun 5;152:139-154. Epub 2021 Jun 5.

Dept. of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122, Essen, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany.

Introduction: Cutaneous melanoma is notorious for the development of in-transit metastases (ITM). For unknown biological reasons, ITM remain the leading tumour manifestation without progression to distant sites in some patients.

Methods: In total, 191 patients with initially unresectable stage III ITM and satellite metastases from 16 skin cancer centres were retrospectively evaluated for their tumour characteristics, survival and therapy response. Read More

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Salmon food matrix influences digestion and bioavailability of long-chain omega-3 polyunsaturated fatty acids.

Food Funct 2021 Jun 8. Epub 2021 Jun 8.

Riddet Institute, Massey University, Private Bag 11222, Palmerston North 4442, New Zealand and Nutraceuticals Research Program, School of Biomedical Sciences & Pharmacy, University of Newcastle, Callaghan, NSW 2308, Australia.

The natural structure of whole food plays an important role in the physiological impact of bioactive compounds present within the food, also known as the "matrix effect". Long-chain omega-3 polyunsaturated fatty acids (LCn-3PUFAs) are one example of a food-derived nutrient, mostly found in fish, that is believed to be influenced by the food matrix. However, most previous studies have compared only the long-term bioavailability of fish versus fish oil and have used commercial sources of fish oil. Read More

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Exploiting nonlinear wave propagation to improve the precision of ultrasonic flow meters.

Ultrasonics 2021 Jun 2;116:106476. Epub 2021 Jun 2.

Delft University of Technology, Department of Imaging Physics, Laboratory of Medical Imaging, Lorentzweg 1, 2628CJ, Delft, The Netherlands; Erasmus MC, Thorax Center, Department of Biomedical Engineering, Doctor Molewaterplein 40, 3015GD, Rotterdam, The Netherlands.

Acoustic wave propagation in ultrasonic flow measurements is typically assumed to be linear and reciprocal. However, if the transmitting transducer generates a sufficiently high pressure, nonlinear wave propagation effects become significant. In flow measurements, this would translate into more information to estimate the flow and therefore a higher precision relative to the linear case. Read More

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Big data insight on global mobility during the Covid-19 pandemic lockdown.

J Big Data 2021 2;8(1):78. Epub 2021 Jun 2.

Tromsø School of Business and Economics, UiT The Arctic University of Norway, Narvik Campus, Lodve Langes gate 2, 8514 Narvik, Norway.

The Covid-19 pandemic that began in the city of Wuhan in China has caused a huge number of deaths worldwide. Countries have introduced spatial restrictions on movement and social distancing in response to the rapid rate of SARS-Cov-2 transmission among its populations. Research originality lies in the taken global perspective revealing indication of significant relationships between changes in mobility and the number of Covid-19 cases. Read More

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Expected Values of Esophageal Transit and Gastric Emptying Scintigraphy Post-uncomplicated Sleeve Gastrectomy.

Obes Surg 2021 Jun 5. Epub 2021 Jun 5.

Monash University Department of Surgery, Central Clinical School, Monash University, Level 6, Alfred Centre, 99 Commercial Rd, Melbourne, VIC, 3004, Australia.

Purpose: Sleeve gastrectomy (SG) results in significant anatomical and physiological alterations of the esophagus and stomach, including food tolerance. Currently, there is no consensus on the parameters of abnormal esophageal transit and gastric emptying in this population. We describe standardized esophageal transit and gastric emptying protocols, and define expected values following an uncomplicated SG. Read More

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Regional Gastrointestinal Motility in Healthy Children.

J Pediatr Gastroenterol Nutr 2021 Jun 3. Epub 2021 Jun 3.

Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark Motilis Medica SA, Lausanne, Switzerland.

Objective: To evaluate the safety and use of the 3D-Transit system (Motilis SA, Lausanne, Switzerland) and to describe regional gastrointestinal transit times, segmental colonic transit times and colonic movement patterns in healthy children.

Methods: 21 healthy children (11 girls, median age 10.5 years, range 7-15 years) were included. Read More

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Diabetic diarrhoea: a study on gastrointestinal motility, pH levels and autonomic function.

J Intern Med 2021 Jun 5. Epub 2021 Jun 5.

Department of Medicine, Haukeland University Hospital, Bergen, Norway.

Background: Chronic diarrhoea is a common, but poorly investigated diabetes complication. Autonomic neuropathy is a leading pathophysiological theory founded on old, small studies. Studies of gastrointestinal motility and pH levels are lacking. Read More

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Physiologically based modelling of tranexamic acid pharmacokinetics following intravenous, intramuscular, sub-cutaneous and oral administration in healthy volunteers.

Eur J Pharm Sci 2021 Jun 1:105893. Epub 2021 Jun 1.

Clinical Trials Unit, London School of Hygiene & Tropical Medicine, London, UK. Electronic address:

Background: Tranexamic acid (TXA) is an antifibrinolytic drug that reduces surgical blood loss and death due to bleeding after trauma and post-partum haemorrhage. Treatment success is dependent on early intervention and rapid systemic exposure to TXA. The requirement for intravenous (IV) administration can in some situations limit accessibility to TXA therapy. Read More

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Molecular perspective concerning fluoride and arsenic mediated disorders on epididymal maturation of spermatozoa: A concise review.

Hum Exp Toxicol 2021 Jun 4:9603271211021474. Epub 2021 Jun 4.

568916Department of Life Sciences, Presidency University, Kolkata, West Bengal, India.

Epididymis is a complex tubular structure of male reproductive system where spermatozoa undergo maturation and gain the fertilizing ability. Epididymal pseudostratified columnar epithelium with different cell types play imperative role by their secretory properties and enrich the luminal microenvironment necessary for achieving spermatozoal motility. During epididymal transit several secretory proteins like P26h, SPAG11, HSPD1 and many others are deposited on spermatozoal surface. Read More

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Direct nanoscopic observation of plasma waves in the channel of a graphene field-effect transistor.

Light Sci Appl 2020 Jun 4;9(1):97. Epub 2020 Jun 4.

Physikalisches Institut, Johann Wolfgang Goethe-Universität, Max-von-Laue-Str. 1, D-60438, Frankfurt am Main, Germany.

Plasma waves play an important role in many solid-state phenomena and devices. They also become significant in electronic device structures as the operation frequencies of these devices increase. A prominent example is field-effect transistors (FETs), that witness increased attention for application as rectifying detectors and mixers of electromagnetic waves at gigahertz and terahertz frequencies, where they exhibit very good sensitivity even high above the cut-off frequency defined by the carrier transit time. Read More

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MTT Heterogeneity in Perfusion CT Imaging as a Predictor of Outcome after Aneurysmal SAH.

AJNR Am J Neuroradiol 2021 Jun 3. Epub 2021 Jun 3.

Diagnostic and Interventional Radiology (K.J., B.T., C.R.), Medical Faculty, University Düsseldorf, Düsseldorf, Germany.

Background And Purpose: Impairment of tissue oxygenation caused by inhomogeneous microscopic blood flow distribution, the so-called capillary transit time heterogeneity, is thought to contribute to delayed cerebral ischemia after aneurysmal SAH but has so far not been systematically evaluated in patients. We hypothesized that heterogeneity of the MTT, derived from CTP parameters, would give insight into the clinical course of patients with aneurysmal SAH and may identify patients at risk of poor outcome.

Materials And Methods: We retrospectively analyzed the heterogeneity of the MTT using the coefficient of variation in CTP scans from 132 patients. Read More

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Malaria Infection is High at Transit and Destination Phases Among Seasonal Migrant Workers in Development Corridors of Northwest Ethiopia: A Repeated Cross-Sectional Study.

Res Rep Trop Med 2021 26;12:107-121. Epub 2021 May 26.

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Purpose: Malaria is a leading public health problem in Ethiopia. Every year, thousands of seasonal farm workers travel to farm corridors in Northwest Ethiopia and fall at risk of malaria infection. However, the magnitude of malaria infection and risk factors during harvest time were not well identified. Read More

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Feasibility of perfusion and early-uptake F-FDG PET/CT in primary hepatocellular carcinoma: a dual-input dual-compartment uptake model.

Jpn J Radiol 2021 Jun 2. Epub 2021 Jun 2.

Faculty of Information Engineering and Automation, Kunming University of Science and Technology, 727 South Jingming Rd., Kunming, Yunnan, China.

Purpose: PET enables a concurrent evaluation of perfusion status and metabolic activity. We aimed to evaluate the feasibility of perfusion and early-uptake F-FDG PET/CT in hepatocellular carcinoma (HCC) using a dual-input dual-compartment uptake model.

Materials And Methods: Data from 5 min dynamic PET/CT and conventional PET/CT scans were retrospectively collected from 17 pathologically diagnosed HCCs. Read More

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Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring.

Braz J Med Biol Res 2021 31;54(9):e11116. Epub 2021 May 31.

Instituto de Ciências Biológicas e da Saúde, Universidade Federal de Mato Grosso, Barra do Garças, MT, Brasil.

The interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. Read More

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Imaging of nanoparticle uptake and kinetics of intracellular trafficking in individual cells.

Nanoscale 2021 Jun;13(23):10436-10446

Department of Nanomedicine & Drug Targeting, Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan 1, 9713AV Groningen, the Netherlands.

Live cell imaging is a powerful tool to understand how nano-sized objects, such as the drug carriers used for nanomedicine applications, are taken up and trafficked by cells. Here we visualized human HeLa cells as they took up and trafficked nanoparticles of different sizes and quantified nanoparticle colocalization with different fluorescently-labelled intracellular compartments over time. This allowed us to obtain kinetic profiles of nanoparticle transport towards the lysosomes in individual cells. Read More

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