182 results match your criteria transforms hydrophobic

Concurrent self-regulated autonomous synthesis and functionalization of pH-responsive giant vesicles by a chemical pH oscillator.

Soft Matter 2021 Mar 5. Epub 2021 Mar 5.

Department of Earth and Planetary Science and Origins of Life Initiative, Harvard University, 20 Oxford Street, Cambridge, Massachusetts 02138, USA. and Santa Fe Institute, Santa Fe, New Mexico 87501, USA.

The semibatch BrO3--SO32- pH oscillator serves as the radical source for the in situ polymerization of the pH-responsive 2-(diisopropylamino)-ethyl methacrylate monomer on poly(ethylene-glycol)-macroCTA chain and generates an amphiphilic block copolymer. These building blocks concurrently self-assemble to micelles and then transforms to vesicles as the chain length of the hydrophobic block growths. Large amplitude oscillations in the concentration of H+ by the semibatch BrO3--SO32- are provoked when the conditions in the system are favorable. Read More

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Fluorescence Switchable Conjugated Polymer Microdisk Arrays by Cosolvent Vapor Annealing.

Polymers (Basel) 2021 Jan 15;13(2). Epub 2021 Jan 15.

Department of Materials Science, Faculty of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8573, Ibaraki, Japan.

Depositing minute light emitters into a regular array is a basic but essential technique in display technology. However, conventional lithographic methodologies involve multistep and energy-consuming processes. Here, we develop a facile method in which organic and polymeric fluorescent dyes spontaneously aggregate to form a patterned microarray. Read More

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January 2021

Construction and characterization of a temperature-responsive nanocarrier for imidacloprid based on mesoporous silica nanoparticles.

Colloids Surf B Biointerfaces 2021 Feb 12;198:111464. Epub 2020 Nov 12.

Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, PR China. Electronic address:

Nanopesticides have great potential applications due to their stability enhancement, sustained release and target affinity. In this work, a temperature-responsive nanocarrier for imidacloprid (IMI) was constructed using mesoporous silica nanoparticles (MSNs) as the core and paraffin wax (PW) as the outer layer. IMI was loaded into MSNs by screening the drug/carrier mass ratios to obtain the optimized IMI/MSNs formulation with a high drug loading (27. Read More

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February 2021

Hydrochannel-Containing Hydrophobic Polymers by Inverse Emulsion Polymerization for Moisture-Driven Actuators.

ACS Appl Mater Interfaces 2020 Dec 23;12(49):55223-55230. Epub 2020 Nov 23.

Materials Science and Engineering Program, University of California, San Diego, 9500 Gilman Dr., La Jolla, California 92093, United States.

Two physical properties in polymers, hydrophobic and water-absorptive, are known to be incompatible. However, human skin in nature has a hydrophobic surface and yet absorbs water throughout hydrophilic amino acid sequences in filaggrin, one of the abundant proteins in our outermost skin layer. Although present in nature, a hydrophilic path network in a hydrophobic polymer is difficult to synthesize because of poor wettability and immiscibility between the two types of materials. Read More

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December 2020

Adsorption of Myoglobin and Corona Formation on Silica Nanoparticles.

Langmuir 2020 12 19;36(47):14157-14165. Epub 2020 Nov 19.

Cain Department of Chemical Engineering, Louisiana State University, Baton Rouge, Louisiana 70808, United States.

The adsorption of proteins from aqueous medium leads to the formation of protein corona on nanoparticles. The formation of protein corona is governed by a complex interplay of protein-particle and protein-protein interactions, such as electrostatics, van der Waals, hydrophobic, hydrogen bonding, and solvation. The experimental parameters influencing these interactions, and thus governing the protein corona formation on nanoparticles, are currently poorly understood. Read More

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December 2020

Self-assembly of N-terminal Alzheimer's β-amyloid and its inhibition.

Biochem Biophys Res Commun 2021 01 2;534:950-956. Epub 2020 Nov 2.

Shanghai Food Safety and Engineering Technology Research Center, Key Lab of Urban Agriculture (South), Bor S. Luh Food Safety Research Center, School of Agriculture & Biology, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address:

Peptide sequence modulates amyloid fibril formation and triggers Alzheimer's disease. The N-terminal region of amyloid peptide is disordered and lack any specific secondary structure. An ionic interaction of Aβ with factor XII is critical for the activation of the contact system in Alzheimer's disease. Read More

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January 2021

Polyphenol binding disassembles glycation-modified bovine serum albumin amyloid fibrils.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Feb 25;246:119001. Epub 2020 Sep 25.

Shanghai Food Safety and Engineering Technology Research Center, Key Lab of Urban Agriculture (South), Bor S. Luh Food Safety Research Center, School of Agriculture & Biology, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address:

Glycation of protein results in the formation of advanced glycation end-products (AGEs) and leads to deposition as amyloid fibrils. Adhesive structural properties of polyphenols to aromatic amino acids draw significance in promoting, accelerating and/or stabilizing on-pathway and off-pathway folding intermediates, although the mechanistic action remains unclear. In this study, polyphenols remodeling mature AGEs modified amyloid fibrils were investigated through UV-visible spectroscopy, fluorescence spectroscopy, transmission electron microscopy, atomic force microscopy, circular dichroism spectroscopy, MALDI-MS/MS analysis and molecular docking studies. Read More

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February 2021

Bio-inspired surface modification of PEEK through the dual cross-linked hydrogel layers.

J Mech Behav Biomed Mater 2020 12 19;112:104032. Epub 2020 Aug 19.

School of Materials Science and Engineering, Nanjing University of Science and Technology, 210094, Nanjing, China; Jiangsu Key Laboratory of Advanced Micro/Nano Materials and Technology, 210094, Nanjing, China.

The biocompatible high-performance material PEEK (polyetheretherketone) is an attractive implant material, however, its hydrophobicity and high friction coefficients severely hinder its biomedical applications. Thus, it is inferred from the recent advances in surface modification technology, achieving the biomimetic natural joint lubrication systems on PEEK still remains a challenge. In view of the above, herein we proposed a novel two-step strategy to fabricate a "soft (dual cross-linked hydrogel) layer-hard (PEEK) substrate" texture that mimics the structure and function of soft cartilage on the hard basal bone in joints. Read More

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December 2020

Biopolymeric Membrane Enriched with Chitosan and Silver for Metallic Ions Removal.

Polymers (Basel) 2020 Aug 10;12(8). Epub 2020 Aug 10.

The National Institute for Research & Development in Chemistry and Petrochemistry-ICECHIM, Splaiul Independentei No. 202, 060021 Bucharest, Romania.

The present paper synthesized, characterized, and evaluated the performance of the novel biopolymeric membrane enriched with cellulose acetate and chitosan (CHI)-silver (Ag) ions in order to remove iron ion from the synthetic wastewater using a new electrodialysis system. The prepared membranes were characterized by Fourier Transforms Infrared Spectroscopy-Attenuated Total Reflection (FTIR-ATR), Thermal Gravimetric Analysis (TGA) and Differential Thermal Analysis (DSC), contact angle measurements, microscopy studies, and electrochemical impedance spectroscopy (EIS). The electrodialysis experiments were performed at the different applied voltages (5, 10, and 15 V) for one hour, at room temperature. Read More

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Photo-degradable micelles for co-delivery of nitric oxide and doxorubicin.

J Mater Chem B 2020 08 13;8(31):7009-7017. Epub 2020 Jul 13.

CAS Key Laboratory of Soft Matter Chemistry, Hefei National Laboratory for Physical Science at the Microscale, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei 230026, Anhui, China.

The emerging therapeutic potential of nitric oxide (NO) has spurred the rapid development of NO donors to maximize the therapeutic outcomes. Although polymeric NO donors have shown extended release times and optimized biodistributions, many of these macromolecular NO donors are non-degradable. Herein, we devise a macromolecular NO donor by integrating photoresponsive N,N'-dinitroso-p-phenylenediamine (DNP) derivatives into the middle block of an amphiphilic triblock copolymer and the photo-mediated NO release process transforms the DNP to quinondimine (QDI) moieties, enabling the degradation of the resulting polymers due to the spontaneous hydrolysis of QDI moieties. Read More

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An Antifreezing/Antiheating Hydrogel Containing Catechol Derivative Urushiol for Strong Wet Adhesion to Various Substrates.

ACS Appl Mater Interfaces 2020 Jul 30;12(28):32031-32040. Epub 2020 Jun 30.

Fujian Provincial Key Laboratory of Polymer Materials, College of Chemistry and Materials Science, Fujian Normal University, Fujian 350007, China.

Tough adhesive hydrogels that can tightly bond to wet tissue/polymer/ceramic/metal surfaces have great potentials in various fields. However, conventional adhesive hydrogels usually show short-term and nonreversible adhesion ability, as the water component in a hydrogel readily transforms to vapor or ice in response to fluctuation of environment temperature, hindering their applications in extreme conditions such as in freezing Arctic and roasting Africa. For the first time, urushiol (UH), a natural catechol derivative with a long alkyl side chain, is used as a starting material to copolymerize with acrylamide for fabricating adhesive hydrogels, which contain hydrophobic/hydrophilic moieties, antifreezing agent, and adhesive catechol groups. Read More

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Gelation of the internal core of liposomes as a strategy for stabilization and modified drug delivery II. Theoretical analysis and modelling of in-vitro release experiments.

Int J Pharm 2020 Jul 29;585:119471. Epub 2020 May 29.

Dipartimento di Ingegneria Chimica, Materiali e Ambiente, Sapienza Università di Roma, Via Eudossiana 18, 00184 Rome, Italy.

PEG-DMA was incorporated in unilamellar liposomes. PEG-DMA crosslinking by photo-induced radical reaction transforms the liquid aqueous core of the liposome into a hydrogel. The molecular weight of PEG-DMA significantly influences both structural and release properties of these hybrid nanosystems, by affecting both membrane permeability and diffusional properties of the inner core. Read More

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Cavity Particle in Aqueous Solution with a Hydrophobic Solute: Structure, Energetics, and Functionals.

J Phys Chem B 2020 06 12;124(25):5220-5237. Epub 2020 Jun 12.

Center for Biophysics and Computational Biology, and Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, United States.

Endpoints density functional theory (DFT) provides a framework for calculating the excess chemical potential of a solute in solution using solvent distribution functions obtained from both physical endpoints of a hypothetical charging process which transforms the solvent density from that of the pure liquid to the solution state. In this work, the endpoints DFT equations are formulated in terms of the indirect (solvent-mediated) contribution ω() to the solute-solvent potential of mean force, and their connections are established with the conventional DFT expressions which are based on the use of direct correlation functions. ω actually corresponds to the free-energy cost to move a cavity particle (a tagged solvent molecule which interacts with the other solvent molecules but not the solute) from the bulk to the configuration of a solvent molecule relative to the solute and is a suitable variable to describe the solvent effects on the solute-solvent interactions. Read More

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Autogenous Production and Stabilization of Highly Loaded Sub-Nanometric Particles within Multishell Hollow Metal-Organic Frameworks and Their Utilization for High Performance in Li-O Batteries.

Adv Sci (Weinh) 2020 May 16;7(9):2000283. Epub 2020 Mar 16.

Department of Materials Science and Engineering and NanoCentury KAIST Institute Korea Advanced Institute of Science and Technology (KAIST) 291 Daehak-ro, Yuseong-gu Daejeon 34141 Republic of Korea.

Sub-nanometric particles (SNPs) of atomic cluster sizes have shown great promise in many fields such as full atom-to-atom utilization, but their precise production and stabilization at high mass loadings remain a great challenge. As a solution to overcome this challenge, a strategy allowing synthesis and preservation of SNPs at high mass loadings within multishell hollow metal-organic frameworks (MOFs) is demonstrated. First, alternating water-decomposable and water-stable MOFs are stacked in succession to build multilayer MOFs. Read More

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Different submicellar solubilization mechanisms revealed by H NMR and 2D diffusion ordered spectroscopy (DOSY).

Phys Chem Chem Phys 2020 May 6;22(19):11075-11085. Epub 2020 May 6.

Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, State Key Laboratory of Physical Chemistry of Solid Surfaces, Xiamen University, Xiamen, China.

Different submicellar solubilization mechanisms of two systems, Triton X-100 (TX-100)/tetradecane and sodium dodecyl sulfate (SDS)/butyl methacrylate, are revealed on the molecular scale by H NMR spectroscopy and 2D diffusion ordered spectroscopy (DOSY). It is evident that the apparent solubilities of both tetradecane and butyl methacrylate are enhanced, even at much lower surfactant concentrations than the CMCs. Solubilized solutes also contribute to the early formation of surfactant micelles. Read More

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Rheology of Water Flows Confined between Multilayer Graphene Walls.

Langmuir 2020 May 15;36(20):5633-5646. Epub 2020 May 15.

The School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, E1 4NS London, United Kingdom.

Water confined by hydrophilic materials shows unique transport properties compared to bulk water, thereby offering new opportunities for the development of nanofluidic devices. Recent experimental and numerical studies showed that nanoconfined water undergoes liquid- to solid-phase-like transitions depending on the degree of confinement. In the case of water confined by graphene layers, the van der Waals forces are known to deform the graphene layers, whose bending leads to further nonuniform confinement effects. Read More

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Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation.

Elife 2020 03 10;9. Epub 2020 Mar 10.

Center for Integrated Protein Science Munich at the Department Chemie, Technische Universität München, Garching, Germany.

In systemic light chain amyloidosis, an overexpressed antibody light chain (LC) forms fibrils which deposit in organs and cause their failure. While it is well-established that mutations in the LC's V domain are important prerequisites, the mechanisms which render a patient LC amyloidogenic are ill-defined. In this study, we performed an in-depth analysis of the factors and mutations responsible for the pathogenic transformation of a patient-derived λ LC, by recombinantly expressing variants in . Read More

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The effect of surface modification on chemical and crystalline structure of the cellulose III nanocrystals.

Carbohydr Polym 2020 May 8;235:115962. Epub 2020 Feb 8.

State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou 510640, China.

Although the research on the cellulose allomorphs has been progressing for decades, many details especially in a nanoscale still require further exploration. In this article, the crystalline structure and morphology of cellulose III nanocrystals (CNC-III) are investigated after some typical modification routes. The results indicate that the crystalline structure of CNC-III is unsteady. Read More

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Evaporative Drying of Sodium Chloride Solution Droplet on a Thermally Controlled Substrate.

J Phys Chem B 2020 02 11;124(7):1266-1274. Epub 2020 Feb 11.

Instability and Soft Patterning Laboratory, Department of Chemical Engineering , Indian Institute of Technology Kharagpur , Kharagpur 721 302 , West Bengal , India.

We report the evaporative drying-mediated pattern formation of dilute aqueous NaCl solution droplets on a hydrophobic surface made of cross-linked PDMS at elevated temperatures. Experiments were performed with various salt concentrations (0.08 to 2 M). Read More

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February 2020

Tough Ordered Mesoporous Elastomeric Biomaterials Formed at Ambient Conditions.

ACS Nano 2020 01 20;14(1):241-254. Epub 2019 Dec 20.

Synthetic dry elastomers are randomly cross-linked polymeric networks with isotropic and unordered higher-level structural features. However, their growing use as soft-tissue biomaterials has demanded the need for an ordered and anisotropic nano-micro (or) mesoarchitecture, which is crucial for imparting specific properties such as hierarchical toughening, anisotropic mechanics, sustained drug delivery, and directed tissue growth. High processing cost, poor control in 3D, and compromised mechanical properties have made it difficult to synthesize tough and dry macroscopic elastomers with well-organized nano-microstructures. Read More

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January 2020

Macroscopic Self-Evolution of Dynamic Hydrogels to Create Hollow Interiors.

Angew Chem Int Ed Engl 2020 Mar 29;59(14):5611-5615. Epub 2020 Jan 29.

Institute of Fundamental and Frontier Science, University of Electronic Science and Technology of China, Chengdu, 610054, China.

A solid-to-hollow evolution in macroscopic structures is challenging in synthetic materials. A fundamentally new strategy is reported for guiding macroscopic, unidirectional shape evolution of materials without compromising the material's integrity. This strategy is based on the creation of a field with a "swelling pole" and a "shrinking pole" to drive polymers to disassemble, migrate, and resettle in the targeted region. Read More

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Crosslinking Kinetics of Methylcellulose Aqueous Solution and Its Potential as a Scaffold for Tissue Engineering.

Polymers (Basel) 2019 Oct 28;11(11). Epub 2019 Oct 28.

Institute of Fundamental Technological Research, Polish Academy of Sciences, Pawinskiego 5b St., 02-106 Warsaw, Poland.

Thermosensitive, physically crosslinked injectable hydrogels are in the area of interests of various scientific fields. One of the representatives of this materials group is an aqueous solution of methylcellulose. At ambient conditions, methylcellulose (MC) is a sol while on heating up to 37 °C, MC undergoes physical crosslinking and transforms into a gel. Read More

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October 2019

Cyclodextrin supramolecular inclusion-enhanced pyrene excimer switching for highly selective detection of RNase H.

Anal Chim Acta 2019 Dec 27;1088:137-143. Epub 2019 Aug 27.

State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China.

Here, we report a novel fluorescence method for the highly selective and sensitive detection of RNase H by combining the use of a dual-pyrene-labeled DNA/RNA duplex with supramolecular inclusion-enhanced fluorescence. Initially, the probe is in the "off" state due to the rigidness of the double-stranded duplex, which separates the two pyrene units. In the presence of RNase H, the RNA strand of the DNA/RNA duplex will be hydrolyzed, and the DNA strand transforms into a hairpin structure, bringing close the two pyrene units which in turn enter the hydrophobic cavity of a γ-cyclodextrin. Read More

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December 2019

Phase Diagram of Nanoscale Water on Solid Surfaces with Various Wettabilities.

Hu Qiu Wanlin Guo

J Phys Chem Lett 2019 Oct 3;10(20):6316-6323. Epub 2019 Oct 3.

State Key Laboratory of Mechanics and Control of Mechanical Structures and Key Laboratory for Intelligent Nano Materials and Devices of MOE, Institute of Nano Science , Nanjing University of Aeronautics and Astronautics , Nanjing 210016 , China.

Understanding structural and dynamic properties of water in contact with solid surfaces is essential for diverse fields, including environmental sciences, nanofluidics, lubrication, and electrochemistry. Despite tremendous efforts, how interfacial water phase behaviors correlate with a surface's wettability remains elusive. Here, we investigate the structure and dynamics of nanoscale water droplets or adlayers on solid surfaces with wettabilities spanning from strongly hydrophobic to strongly hydrophilic using extensive molecular dynamics simulations. Read More

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October 2019

Visible Light-Activated Self-Recovery Hydrophobic CeO/Black TiO Coating Prepared Using Air Plasma Spraying.

ACS Appl Mater Interfaces 2019 Oct 26;11(40):37209-37215. Epub 2019 Sep 26.

School of Materials , University of Manchester , MSS Tower , Manchester M13 9PL , U.K.

Hydrophobic coatings are widely used in many areas from home to industry. However, the hydrophobicity can be easily degraded by adsorption of the atmospheric contaminations. In this study, a novel CeO/black TiO hydrophobic coating with self-recovery capability is prepared using air plasma spraying without any chemical modification. Read More

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October 2019

Memory-kernel extraction for different molecular solutes in solvents of varying viscosity in confinement.

Phys Rev E 2019 Jul;100(1-1):012126

Department of Physics, Freie Universität Berlin, 14195 Berlin, Germany.

The friction coefficient of molecular solutes depends on the solute, on the solvent, and on the solute-solvent interactions, but is typically assumed to not depend on an externally applied force that acts on the solute. In this paper we compute the friction memory function from molecular dynamics simulations and show that the friction coefficients of harmonically confined methane, water, Na^{+}, an artificial Na^{-} ion, and glycerol in water in fact increase with confinement strength. The results show that the friction increase with confinement strength is a fundamental effect that occurs for hydrophobic, hydrophilic, as well as charged molecules. Read More

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Hydrophobic silane coating films for the inhibition of water ingress into the nanometer pore of calcium silicate hydrate gels.

Phys Chem Chem Phys 2019 Sep 30;21(35):19026-19038. Epub 2019 Aug 30.

Shanghai Jiaotong University, Shanghai, China.

The super-hydrophobic nature of surfaces is greatly dependent on the interfacial molecular structure of coating materials. In this study, to understand the structure, dynamics and interfacial behavior of hydrophobic coating, molecular dynamics is utilized to study the capillary transport of water molecules through the nanometer channel of calcium silicate hydrate (C-S-H) with the interior surface impregnated with silane. The C-S-H surface is coated by connecting the bridging silicate tetrahedron with an oxygen-containing group in isobutyl-triethoxysilane (CHOSi) with a silane molecule coverage rate ranging from 25% to 100%. Read More

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September 2019

Micro-Raman and density functional theory analyses of ion pairs in concentrated sodium tetrahydroxyborate droplets.

Spectrochim Acta A Mol Biomol Spectrosc 2020 Jan 29;224:117308. Epub 2019 Jul 29.

The Institute of Chemical Physics, School of Chemistry, Beijing Institute of Technology, Beijing 100081, People's Republic of China. Electronic address:

In this study, ion pairs in a single sodium tetrahydroxyborate [Na [B(OH)] droplet were analyzed using an "in-situ strategy" in which a sample-droplet of nanogram mass was deposited on a hydrophobic substrate and droplet was forced to enter into a supersaturated state by decreasing the relative humidity (RH) of the environment. The structure of the solvated [B(OH)] ionic moiety with various molar water-to-solute ratios (WSR) was analyzed using Raman spectroscopy. To confirm the structural changes in the droplet, electronic structure calculations were carried out using density functional theory (DFT). Read More

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January 2020

Temperature-Activated PEG Surface Segregation Controls the Protein Repellency of Polymers.

Langmuir 2019 07 12;35(30):9769-9776. Epub 2019 Jul 12.

Ames Laboratory , Iowa State University , Ames , Iowa 50011 , United States.

Poly(ethylene glycol) (PEG) is widely used to modulate the hydration states of biomaterials and is often applied to produce nonfouling surfaces. Here, we present X-ray scattering data, which show that it is the surface segregation of PEG, not just its presence in the bulk, that makes this happen by influencing the hydrophilicity of PEG-containing substrates. We demonstrate a temperature-dependent trigger that transforms a PEG-containing substrate from a protein-adsorbing to a protein-repelling state. Read More

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Insights into thermodynamic mechanisms driving bisphenol A (BPA) binding to extracellular polymeric substances (EPS) of activated sludge.

Sci Total Environ 2019 Aug 4;677:502-510. Epub 2019 May 4.

State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.

Bisphenol A (BPA) in wastewater has high risks of causing biological feminization. During the wastewater treatment process, large amounts of BPA are accumulated in activated sludge. However, the mechanisms of BPA interacted with activated sludge are still unclear. Read More

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