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Am J Cardiol 2022 May 18. Epub 2022 May 18.

Department of Medicine, Division of Cardiology, University Hospitals Harrington Heart & Vascular Institute, Case Western Reserve University School of Medicine, Cleveland, Ohio. Electronic address:

Previous studies reported that new-onset persistent left bundle branch block (NOP-LBBB) was related to worse outcomes after transcatheter aortic valve implantation (TAVI). However, these results can be confounded by the presence of permanent pacemaker (PPM) implantation before and after TAVI. Long-term outcomes and the risk stratification of NOP-LBBB not having PPM implantation before and after TAVI have not been fully investigated. Read More

Int J Cardiol 2022 May 18. Epub 2022 May 18.

Department of Cardiology, Queen Elizabeth University Hospital, Mindelsohn Way, Edgbaston, Birmingham B15 2WB, UK; Institute for Cardiovascular Sciences, College of Medical & Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.. Electronic address:

Background: Small studies have suggested left ventricular (LV) rapid pacing has similar safety and efficacy to conventional right ventricular (RV) rapid pacing in transcatheter aortic valve implantation (TAVI). However, there are limited data on the comparative rates of tamponade. The study compared the rate of cardiac tamponade between LV and RV-pacing during TAVI. Read More

J Am Coll Cardiol 2022 May 13. Epub 2022 May 13.

Quebec Heart & Lung Institute, Laval University, Quebec City, Canada.

Background: Data comparing valve systems in the valve-in-valve transcatheter aortic valve replacement (ViV-TAVR) field has been obtained from retrospective studies.

Objectives: To compare the hemodynamic results between the balloon-expandable SAPIEN (3/ULTRA) (BEV) and self-expanding Evolut (R/PRO/PRO+) (SEV) valves in ViV-TAVR.

Methods: Patients with a failed small (≤23 mm) surgical valve. Read More

JACC Cardiovasc Interv 2022 May 10. Epub 2022 May 10.

Civil Hospital and University of Brescia, Brescia, Italy.

Objectives: The aim of this study was to assess the efficacy and safety of the ACURATE neo2 transcatheter heart valve (THV) in patients with severe aortic valve stenosis.

Background: The first-generation ACURATE neo THV was associated with a non-negligible occurrence of moderate or greater paravalvular aortic regurgitation (AR) following transcatheter aortic valve replacement. To overcome this issue, the ACURATE neo2 iteration, which incorporates a taller outer skirt aimed at reducing the occurrence of paravalvular AR, has recently been developed. Read More

Cardiovasc Revasc Med 2022 Jun 2;39:26-27. Epub 2022 Apr 2.

Medical University of South Carolina, Charleston, SC, United States of America. Electronic address:

J Am Coll Cardiol 2022 May 14. Epub 2022 May 14.

Clinical Trials Center, Cardiovascular Research Foundation, New York, New York; St. Francis Hospital and Heart Center, Roslyn, New York.

Background: The impact of aortic valve replacement (AVR) on progression/regression of extra-valvular cardiac damage and its association with subsequent prognosis is unknown.

Objectives: To describe evolution of cardiac damage post-AVR and its association with outcomes.

Methods: Patients undergoing transcatheter or surgical AVR from the PARTNER 2 and 3 trials were pooled and classified by cardiac damage stage at baseline and 1-year (Stage 0, no damage; Stage 1, left ventricular damage; Stage 2, left atrial or mitral valve damage; Stage 3, pulmonary vasculature or tricuspid valve damage; Stage 4, right ventricular damage). Read More

J Invasive Cardiol 2022 May 19. Epub 2022 May 19.

Interventional Cardiology Department, Mazzoni Hospital, Via degli Iris 1, 63100 Ascoli Piceno, Italy.

Background: Percutaneous balloon aortic valvuloplasty (BAV) is actually recommended as a bridge to surgery or transcatheter aortic valve replacement in patients with severe aortic stenosis (AS) in particular clinical settings. In this pilot study, for the first time, we report our experience utilizing a nonocclusive balloon for BAV, which does not require rapid ventricular pacing (RVP), in high-risk symptomatic elderly patients with severe AS.

Methods And Results: From 2018 to 2020, a total of 30 high-risk elderly patients with heart failure due to severe AS were treated with BAV and were all prospectively included in the study. Read More

J Invasive Cardiol 2022 May 19. Epub 2022 May 19.

Kerckhoff Heart Center, Department of Cardiology, 61231 Bad Nauheim, Germany.

Background: Data are lacking regarding the outcomes of balloon postdilation (BPD) for the Acurate neo and neo2 devices. The aim of this study was to assess the impact of BPD in a large, single-center cohort of patients treated with the Acurate platform.

Methods: For this retrospective analysis, we included all patients with severe aortic stenosis who underwent transfemoral transcatheter aortic valve replacement (TAVR) with the Acurate neo or neo2 prosthesis at our institution. Read More

J Invasive Cardiol 2022 May 19. Epub 2022 May 19.

62 W Seventh Ave, Suite 450, Spokane, WA 99204 USA.

Background: Patients with small aortic annuli (SAA) are prone to higher post-transcatheter aortic valve replacement (TAVR) transvalvular gradients and development of prosthesis-patient mismatch (PPM). In many patients with SAA, the choice of TAVR valve commonly involves choosing between the 26-mm Medtronic Evolut 2 (ME26) or the 23-mm Edwards Sapien 3 valve (ES23). We compared echocardiographic and clinical outcomes in patients with SAA undergoing TAVR with either valve. Read More

EuroIntervention 2022 May 20. Epub 2022 May 20.

Cuspa LTD, Nazareth, Israel.

Eur Heart J Case Rep 2022 May 3;6(5):ytac192. Epub 2022 May 3.

Division of Cardiovascular Surgery, Hokkaido Cardiovascular Hospital, 1-30 South27 West13, Chuo-ku, Sapporo City 064-8622, Japan.

Background: Single coronary artery is a rare coronary artery anomaly with an incidence of <0.03%. The coexistence of coronary artery anomalies with severe aortic stenosis is extremely rare. Read More

Zhonghua Xin Xue Guan Bing Za Zhi 2022 May;50(5):509-511

Department of Cardiology, Zhongshan Hospital, Fudan University, Research Unit of Cardiovascular Techniques and Devices, Chinese Academy of Medical Sciences, National Clinical Research Center for Interventional Medicine, Shanghai 200032, China.

EuroIntervention 2022 May 19. Epub 2022 May 19.

Quebec Heart & Lung Institute, Laval University, Quebec City, Canada.

Eur Heart J 2022 May 19. Epub 2022 May 19.

J Med Ultrason (2001) 2022 May 18. Epub 2022 May 18.

Department of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.

Eur Heart J 2022 May 18. Epub 2022 May 18.

Sorbonne Université, ACTION Group, INSERM UMRS 1166, Hôpital Pitié-Salpêtrière (AP-HP), Institut de Cardiologie, Paris 75013, France.

Aims: The respective roles of oral anticoagulation or antiplatelet therapy following transcatheter aortic valve implantation (TAVI) remain debated. ATLANTIS is an international, randomized, open-label, superiority trial comparing apixaban to the standard of care.

Methods And Results: After successful TAVI, 1500 patients were randomized (1:1) to receive apixaban 5 mg (2. Read More

Open Heart 2022 May;9(1)

Cardiology, Norfolk and Norwich University Hospital, Norwich, UK.

Objectives: The management of severe aortic stenosis mandates consideration of aortic valve intervention for symptomatic patients. However, for asymptomatic patients with severe aortic stenosis, recent randomised trials supported earlier intervention. We conducted a systematic review and meta-analysis to evaluate all the available data comparing the two management strategies. Read More

JAMA 2022 05;327(19):1870-1871

Division of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

JAMA 2022 05;327(19):1875-1887

Department of Cardiovascular Medicine, University of Manchester, Manchester, England.

Importance: Transcatheter aortic valve implantation (TAVI) is a less invasive alternative to surgical aortic valve replacement and is the treatment of choice for patients at high operative risk. The role of TAVI in patients at lower risk is unclear.

Objective: To determine whether TAVI is noninferior to surgery in patients at moderately increased operative risk. Read More

Eur J Heart Fail 2022 May 17. Epub 2022 May 17.

Faculty of Medicine, University of Oslo, Oslo, Norway.

Aims: The aim of this trial was to evaluate whether intravenous iron could provide benefit beyond transcatheter aortic valve implantation (TAVI) in iron deficient patients with severe aortic stenosis.

Methods And Results: In this randomised, placebo-controlled, double-blinded, single-centre trial, we enrolled patients with severe aortic stenosis and iron deficiency (defined as ferritin < 100 μg/L, or 100-299 μg/L with a transferrin saturation < 20 %) who were evaluated for TAVI. Patients were randomly assigned (1:1) to receive i. Read More

Heart Lung Circ 2022 May 13. Epub 2022 May 13.

Department of Cardiothoracic Surgery, Monash Health, Melbourne, Vic, Australia.

Kardiol Pol 2022 May 16. Epub 2022 May 16.

Department of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, Poznań, Poland.

Background: Pulmonary hypertension related to left ventricle heart disease is a common finding in patients with severe aortic stenosis treated with transcatheter aortic valve implantation (TAVI) and is associated with higher mortality rate.

Aims: The aim of the study was to analyze the influence of pulmonary artery systolic pressure (PASP) changes after TAVI on long-term survival.

Methods: TAVI was performed in 362 patients between January 2013 and December 2018. Read More

JACC Case Rep 2022 May 4;4(9):543-548. Epub 2022 May 4.

Mohammed Bin Khalifa Specialist Cardiac Centre (MKCC), Awali, Kingdom of Bahrain.

Hydrophilic polymers are frequently used as surface coatings in modern intravascular technologies. We hereby present a case of a patient who underwent transcatheter aortic valve implantation that was complicated with foot gangrene and mesenteric ischemia, necessitating emergency enterectomy. Histologic examination revealed hydrophilic polymer emboli as the culprit of these complications. Read More

JACC Case Rep 2022 May 4;4(9):512-515. Epub 2022 May 4.

Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

Contemporary challenges in structural heart intervention include redo transcatheter aortic valve replacement and transcatheter mitral valve replacement in severe mitral annular calcification. We report a case of concomitant redo transcatheter aortic valve replacement and transcatheter mitral valve replacement in mitral annular calcification in a patient with radiation heart disease. (). Read More

EJVES Vasc Forum 2022 1;55:52-55. Epub 2022 Apr 1.

Department of Cardiology, Prince of Wales Hospital, Sydney, Australia.

Introduction: Carotid artery pseudoaneurysm is a rare but potentially morbid complication of central venous catheter insertion. Traditionally managed by open surgical or endovascular repair, this article describes a case that used percutaneous thrombin injection. Delivered at the point of care under ultrasound guidance, it offers a less invasive and less resource dependent approach where conventional therapies are unsuccessful. Read More

Cureus 2022 Apr 12;14(4):e24054. Epub 2022 Apr 12.

Internal Medicine, Dow University of Health Sciences, Civil Hospital Karachi, Karachi, PAK.

Transcatheter aortic valve replacement (TAVR) is a technique that can be performed through multiple approaches, and the benefits of one approach over another are still being evaluated to make sure patients receive the best possible care. Our meta-analysis aims to compare clinical and procedural outcomes of the transaxillary (TAx) and transaortic (TAo) approaches to validate the more optimal procedure. The systematic literature search was done via PubMed/MEDLINE, Embase, and the Cochrane Central databases from inception to December 2021, to identify articles reporting data on both TAx TAVR and TAo TAVR. Read More

Comput Math Methods Med 2022 4;2022:5794681. Epub 2022 May 4.

Department of Catheterization Room, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, 264000 Shandong, China.

To evaluate the clinical application effect of spiral computed tomography (CT) three-dimensional (3D) reconstruction based on artificial intelligence in transcatheter aortic valve implantation (TAVI), a CT 3D reconstruction model based on deep convolutional neural networks (DCNN) was established in this research, which was compared with the model-based iterative reconstruction (MBIR) and used in clinical practice. Then, 62 patients with aortic stenosis (AS) who underwent TAVI surgery were recruited as the research objects. The accuracy, sensitivity, and specificity of the multislice spiral CT scan (MSCT) and transthoracic echocardiography (TTE) in predicting the type of TAVI surgical valve were compared and analyzed. Read More

EuroIntervention 2022 05;18(1):15-18

Department of Cardiology, CHU Rouen, Rouen, France.

Rev Esp Cardiol (Engl Ed) 2022 May 12. Epub 2022 May 12.

Departamento de Cardiología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain; Centro de Investigación Biomédica en Red Enfermedades Cardiovaculares (CIBERCV), Spain. Electronic address:

Introduction And Objectives: We aimed to describe the feasibility and preliminary outcomes of commissural alignment (CA) for the balloon-expandable transcatheter heart valve.

Methods: The relationship among native commissures and transcatheter aortic valve implantation neocommissures was analyzed in 10 consecutive patients with tricuspid severe aortic stenosis undergoing transcatheter aortic valve implantation after guided implantation based on computed tomography analysis with a self-developed software. CA was predicted by in silico bio-modelling in the 10 patients and the calculated rotation was applied during crimping. Read More

Cardiovasc Revasc Med 2022 May 6. Epub 2022 May 6.

Faculty of Medicine, University of S(t) Cyril & Methodius, Interventional Cardiology Department, University Clinic of Cardiology, Mother Theresa, 17, 1000 Skopje, Macedonia. Electronic address: