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A passive and objective measure of recognition memory in Alzheimer's disease using Fastball memory assessment.

Brain 2021 Sep 20. Epub 2021 Sep 20.

Bristol Medical School, University of Bristol, Bristol, UK.

Earlier diagnosis of Alzheimer's disease requires biomarkers sensitive to associated structural and functional changes. While considerable progress has been made in the development of structural biomarkers, functional biomarkers of early cognitive change, unconfounded by effort, practice and level of education, are still needed. We present Fastball, a new EEG method for the passive and objective measurement of recognition memory, that requires no behavioural memory response or comprehension of the task . Read More

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September 2021

Kidney Disease, Hypertension Treatment, and Cerebral Perfusion and Structure.

Am J Kidney Dis 2021 Sep 17. Epub 2021 Sep 17.

Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia PA.

Rationale And Objective: The safety of intensive blood pressure (BP) targets is controversial for persons with chronic kidney disease (CKD). We studied the effects of hypertension treatment on cerebral perfusion and structure in those with and without CKD.

Study Design: Neuroimaging substudy of a randomized trial. Read More

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September 2021

Musculoskeletal Conditions in the Emergency Room: A Teaching Opportunity for Medical Students and Residents.

P R Health Sci J 2021 Jun;40(2):68-74

Department of Physical Medicine, Rehabilitation & Sports Medicine; Department of Physiology and Biophysics, School of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.

Objective: Assess the potential value of an emergency room (ER) for the teaching of musculoskeletal (MSK) medicine to medical students and residents in training.

Methods: Data from all encounters to the ER of a teaching hospital for calendar years 2016-2019 were extracted from an electronic database. Encounters with ICD-10-CM M codes (MSK system) and S codes (injury) were selected (MSK encounters). Read More

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How are you coping with the COVID-19 pandemic? Survey of undergraduate dental students' wellbeing during an unexpected global event.

Eur J Dent Educ 2021 Sep 20. Epub 2021 Sep 20.

Prosthodontics, Faculty of Dentistry, University of Otago, Dunedin, New Zealand.

Background: COVID-19 pandemic has led to major life changes including suspension of dental education programs worldwide. The impact of this unexpected disruption in clinical teaching needs to be assessed.

Aim: The aim of this study was to evaluate the impact of the COVID-19 restriction measures on the undergraduate dental students' perception regarding their physical, mental and social wellbeing as well as financial stress and anxiety for their future careers. Read More

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September 2021

The utility of color normalization for AI-based diagnosis of hematoxylin and eosin-stained pathology images.

J Pathol 2021 Sep 20. Epub 2021 Sep 20.

School of Biomedical Engineering, University of British Columbia, Vancouver, British Columbia, Canada.

The color variation of hematoxylin and eosin (H&E)-stained tissues has presented a challenge for applications of artificial intelligence (AI) in digital pathology. Many color normalization algorithms have been developed in recent years in order to reduce the color variation between H&E images. However, previous efforts in benchmarking these algorithms have produced conflicting results and none have sufficiently assessed the efficacy of the various color normalization methods for improving diagnostic performance of AI systems. Read More

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September 2021

Monitoring post-match fatigue during a competitive season in elite youth soccer players.

J Athl Train 2021 Sep 20. Epub 2021 Sep 20.

1Children's Health and Exercise Research Centre, College of Life & Environmental Sciences, University of Exeter, Exeter, Devon, United Kingdom.

Introduction: Countermovement jump (CMJ) and perceived wellness measures are useful for monitoring fatigue. Fatigue indicators should simultaneously show sensitivity to previous load and demonstrate influence on subsequent physical output; however, this has not been examined. This study examined the efficacy of CMJ and wellness measures to both detect post-match fatigue and predict subsequent physical match output in elite youth soccer. Read More

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September 2021

Tooth retention predicts good physical performance in older adults.

PLoS One 2021 20;16(9):e0255741. Epub 2021 Sep 20.

Department of Medicine DIMED, University of Padova, Padova, Italy.

Background: Oral health is closely related to both physical and psychological well-being, as it enables individuals to eat, speak, and socialize. The number of teeth is the most used indicator of oral health. Several reports document a relationship of dental status with a variety of indicators of general health but longitudinal studies employing standardized physical performance tests are infrequent in the scientific literature. Read More

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September 2021

E-learning and Web-based Tools for Psychosocial Interventions Addressing Neuropsychiatric Symptoms of Dementia during the COVID-19 pandemic: Quasi-Experimental Study Assessing Feasibility and Efficacy in Tokyo, Japan.

JMIR Med Educ 2021 Sep 19. Epub 2021 Sep 19.

Research Center for Social Science & Medicine, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, JP.

Background: Concern has been raised that the COVID-19 pandemic and consequent social distancing measures may increase neuropsychiatric symptoms in people with dementia. Thus, we developed and delivered an e-learning training course to professional caregivers on using a web-based tool for psychosocial interventions for people with dementia.

Objective: The objective of our study was to evaluate the feasibility and efficacy of an e-learning course in combination with a web-based tool in addressing neuropsychiatric symptoms of dementia. Read More

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September 2021

Vitamin D levels in post-acute hip fractured patients and their association with rehabilitation outcomes.

Disabil Rehabil 2021 Sep 20:1-8. Epub 2021 Sep 20.

Beit Rivka Geriatric Rehabilitation Center, Petach Tikva, Israel.

Purpose: To report on serum 25-hydroxyvitamin D (25(OH)D) levels in post-acute hip fractured patients, revealed the associations between serum 25(OH)D levels and hip fractured patients' baseline characteristics and rehabilitation outcomes.

Materials And Methods: A retrospective study (9/2017-9/2020) of 493 hip fractured patients. 25(OH)D levels were recorded following the patient's baseline characteristics and outcome measures, including the functional independence measure and motor functional independence measure effectiveness. Read More

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September 2021

Decision Making Within and Outside Standard Operating Procedures: Paradoxical Use of Operational Discretion in Firefighters.

Hum Factors 2021 Sep 20:187208211041860. Epub 2021 Sep 20.

2112 Cardiff University, UK.

Objective: To understand how firefighters' use of rules (i.e., standard operating procedures [SOPs]) and deliberative decision making (i. Read More

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September 2021

Agreement With Pediatric Suprapatellar Bursa Effusion Assessments by Point-of-Care Ultrasound After Remote Training.

Pediatr Emerg Care 2021 Jan 15. Epub 2021 Jan 15.

From the Pediatric Emergency Medicine, Yale University School of Medicine, New Haven, CT.

Background: The ease of instruction for point-of-care ultrasound (POCUS) to detect suprapatellar bursa (SPB) effusions in pediatric patients is unknown. Considering in person limitations because of the coronavirus pandemic, strategies for POCUS education by remote learning are necessary.

Methods: We crafted a 90-minute didactic training that was presented via a remote learning format. Read More

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January 2021

Identifying misconceptions about oral radiology and medicine among dental students.

J Dent Educ 2021 Sep 20. Epub 2021 Sep 20.

School of Dentistry, Department of Clinical and Preventive Dentistry, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.

Purpose/objectives: Misconceptions are learning deficiencies that can lead to inappropriate clinical decision-making in dental practice. Although misconceptions are common among students, they are rarely analyzed in dental education. Thus, this study aimed to identify and analyze students' misconceptions about oral radiology and medicine at a Brazilian dental school. Read More

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September 2021

Development and validation of a nomogram for predicting overall survival in pediatric patients with atypical teratoid/rhabdoid tumors.

Turk Neurosurg 2021 May 3. Epub 2021 May 3.

Lishui Municipal Central Hospital, Department of Orthopedics, Lishui, China.

Aim: The clinical outcomes of patients with atypical teratoid/rhabdoid tumors (ATRTs) are heterogeneous, making it difficult to predict prognosis. This study aimed to construct a reliable prediction model for pediatric ATRT patients.

Material And Methods: Population-based data of patients diagnosed with intracranial ATRT were extracted from the National Cancer Institute\'s Surveillance, Epidemiology, and End Results database. Read More

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Attitudes regarding zygomatic implant surgical and prosthodontic techniques-a cohort questionnaire study.

Oral Maxillofac Surg 2021 Sep 20. Epub 2021 Sep 20.

Department of Maxillofacial Prosthodontics, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK.

Background: Zygomatic implant (ZI) surgery and restoration is a complex procedure, requiring experienced clinicians to execute with success. This study assessed the opinion and clinical experiences of a cohort of practitioners involved in provision of zygomatic implant treatment on aspects of the surgical and prosthodontic procedures.

Method: A survey was distributed among all 176 delegates attending 'Zygomatic 2019' International Conference in the UK, and all delegates completed the survey. Read More

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September 2021

Adequate Iodine Intake among Young Adults in Jiangsu Province, China Despite a Medium Iodine Knowledge Score.

Eur J Investig Health Psychol Educ 2020 Mar 9;10(1):554-563. Epub 2020 Mar 9.

Department of Human Nutrition, University of Otago, 9016 Dunedin, New Zealand.

Lack of iodine knowledge might be a risk factor for inadequate iodine intake in populations. Therefore, we aimed to determine the relationship between iodine knowledge and intake in young Chinese adults. A cross-sectional study was conducted in Suzhou, China. Read More

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Measuring Heart Rate Variability Using Commercially Available Devices in Healthy Children: A Validity and Reliability Study.

Eur J Investig Health Psychol Educ 2020 Jan 10;10(1):390-404. Epub 2020 Jan 10.

Faculty of Health, Discipline of Sport and Exercise Science/University of Canberra, Canberra (ACT) 2617, Australia.

Heart rate variability (HRV) is an accepted method for determining autonomic nervous system activity and cardiovascular risk in various populations. This study assessed the validity and reliability of a commercially available finger photoplethysmography (PPG) system for measuring pediatric HRV in a real-world setting. Sixteen healthy children (4. Read More

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January 2020

Assessing the Quality of Physical Environments of Early Childhood Schools within the Cape Coast Metropolis in Ghana Using a Sequential Explanatory Mixed-Methods Design.

Eur J Investig Health Psychol Educ 2020 Dec 18;10(4):1158-1175. Epub 2020 Dec 18.

Neurocognition and Action-Biomechanics-Research Group, Faculty of Psychology and Sport Sciences, Bielefeld University, D-33501 Bielefeld, Germany.

(1) Background: The last few decades have seen researchers giving considerable attention to the physical context of early childhood care and development (ECCD) centers because many of the underlying processes that link physical context are quite similar to psychosocial environmental factors regarding child development. However, research on the physical environments, and the employees' understanding of the importance of physical environments, is often underestimated. The purpose of this study was to assess the quality of the physical environments of ECCD centers in the Cape Coast Metropolis, Ghana, and ascertain whether being a private or public center (center auspices) would be associated with the quality of its physical environment. Read More

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December 2020

Effects and experience with the Mézières method in people with low back pain: A mixed methods study.

J Back Musculoskelet Rehabil 2021 Sep 10. Epub 2021 Sep 10.

Trauma and Clinical Rehabilitation, Clínica Universidad de La Sabana, Chia, Colombia.

Background: Low back pain (LBP) is one of the most common reasons for visiting the doctor. The Mézières method (MM) emphasises body awareness and uses a global postural rehabilitation approach. It is used in the management of LBP, but its effectiveness has received limited formal evaluation. Read More

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September 2021

Premorbid Educational Attainment and Long-Term Motor Prognosis in Parkinson's Disease.

J Parkinsons Dis 2021 Sep 16. Epub 2021 Sep 16.

Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea.

Background: Premorbid educational attainment is a well-known proxy of reserve, not only with regard to cognition, but also to motor symptoms.

Objective: In the present study, we investigated the relationship between educational attainment and long-term motor prognosis in patients with Parkinson's disease (PD).

Methods: We analyzed 466 patients with de novo PD without dementia who underwent dopamine transporter (DAT) scans and were followed up more than 2 years. Read More

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September 2021

Validity and reliability of the fatigue impact scale in stroke.

Top Stroke Rehabil 2021 Sep 20:1-12. Epub 2021 Sep 20.

Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Gazi University, Ankara, Turkey.

Background: Fatigue is one of the significant problems of post-stroke patients as it causes a decreased quality of life. Although the fatigue impact scale (FIS) is used in stroke, it lacks validation studies.

Objective: This study evaluates the psychometric properties of the FIS in patients with stroke. Read More

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September 2021

Competency-based assessment in nutrition education: A systematic literature review.

J Hum Nutr Diet 2021 Sep 19. Epub 2021 Sep 19.

Department of Sport, Exercise and Nutrition, Galway-Mayo Institute of Technology, Galway, Ireland.

Background: A suitably prepared and qualified nutrition and dietetics workforce is part of the solution to combating the burden of disease. Competency-based assessment is a key part of the education of future workforces. Although there has been recent attention on competency-based assessment in dietetics, there is little exploration of competency-based education for the preparation of nutritionists. Read More

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September 2021

Duloxetine attenuates pain in association with downregulation of platelet serotonin transporter in patients with burning mouth syndrome and atypical odontalgia.

Hum Psychopharmacol 2021 Sep 20:e2818. Epub 2021 Sep 20.

Division of Clinical Sciences and Neuropsychopharmacology, Graduate School of Pharmacy, Meijo University, Nagoya, Japan.

Objective: The aim of this study was evaluation of the association between severity of pain and expression of total or ubiquitinated serotonin transporter (SERT) protein in patients with burning mouth syndrome and atypical odontalgia (BMS/AO), who were treated by duloxetine.

Methods: Patients with BMS/AO were assessed for severity of pain using the visual analog scale (VAS), and expression of total and ubiquitinated SERT protein in platelets before (baseline) and 12 weeks after duloxetine-treatment.

Results: The expression of total and ubiquitinated SERT protein at baseline in all patients (n = 33) were higher and lower, respectively, compared to those in healthy controls. Read More

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September 2021

Enamel matrix derivative effects on palatal mucosa wound healing: Randomized clinical trial.

J Periodontal Res 2021 Sep 19. Epub 2021 Sep 19.

São Paulo State University (UNESP), Division of Periodontics, Institute of Science and Technology, São José dos Campos, Brazil.

Background: This study was conducted to evaluate the clinical, immunologic, and patient-centered outcomes of enamel matrix protein derivative (EMD) on excisional wounds in palatal mucosa.

Materials: Forty-four patients in need of ridge preservation were randomly allocated into two groups: control group (n = 22): open palatal wound after free gingival graft (FGG) harvest and EMD group (n = 22): open palatal wound after FGG harvest that received 0.3 ml of EMD. Read More

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September 2021

Solving an incomplete puzzle: risk factors of low back pain during pregnancy.

Ginekol Pol 2021 Sep 20. Epub 2021 Sep 20.

Department of Obstetrics and Gynecology, Akdeniz University School of Medicine, Akdeniz Üniversitesi Tıp Fakültesi Hastanesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Pınarbaşı Mahallesi, Konyaaltı ANTALYA, TURKEY, 07058 Antalya, Turkey.

Objectives: Low back pain during pregnancy is a common disorder with an obscure etiopathogenesis. This study sought to investigate the association of low back pain by assessing various epidemiologic and clinical risk factors including weight changes, the presence of striae gravidarum, and intraperitoneal adhesions.

Material And Methods: A total of 250 pregnant women between 37 and 40 gestational weeks who were scheduled for cesarean section were included in this multicenter prospective trial. Read More

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September 2021

Health-related quality of life among breast cancer patients compared to cancer survivors and age-matched women in the general population in Vietnam.

Qual Life Res 2021 Sep 20. Epub 2021 Sep 20.

Centre for Public Health, Queen's University Belfast, Belfast, UK.

Purpose: This study compared the health-related quality of life (HRQoL) of breast cancer (BC) patients, survivors, and age-matched women from the general population in Vietnam to address the paucity of HRQoL research and contribute to the robust assessment of BC screening and care in Vietnam.

Methods: The standardised EQ-5D-5L instrument was incorporated in an online survey and a hospital-based face-to-face survey, and together with data from the Vietnam EQ-5D-5L norms study. χ tests assessed EQ-5D health profile associations and a Tobit regression model investigated the association between overall health status (EQ-VAS/utility scores) and sociodemographic and clinical characteristics. Read More

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September 2021

What happens to the lower lumbar spine after marathon running: a 3.0 T MRI study of 21 first-time marathoners.

Skeletal Radiol 2021 Sep 20. Epub 2021 Sep 20.

Institute of Orthopaedics and Musculoskeletal Science, University College London and the Royal National Orthopaedic Hospital, Stanmore, London, UK.

Objective: To better understand the impact of long-distance running on runners' lumbar spines by assessing changes before and after their first marathon run.

Materials And Methods: The lumbar spines of 28 asymptomatic adults (14 males, 14 females, mean age: 30 years old), who registered for their first marathon, the 2019 London Richmond Marathon, were examined 16 weeks before (time point 1) and 2 weeks after (time point 2) the marathon. Participants undertook a pre-race 16-week training programme. Read More

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September 2021

Pushing the bench: A mixed methods study of barriers to and facilitators of identification and referral into depression care by professional nurses in KwaZulu-Natal, South Africa.

SSM Ment Health 2021 Dec 22;1. Epub 2021 Jul 22.

Centre for Rural Health, School of Applied Human Sciences, University of KwaZulu-Natal, Durban, South Africa.

Objective: Integration of mental health and chronic disease services in primary care could reduce the mental health treatment gap and improve associated health outcomes in low-resource settings. Low rates of nurse identification and referral of patients with depression limit the effectiveness of integrated mental health care; the barriers to and facilitators of identification and referral in South Africa and comparable settings remain undefined. This study explored barriers to and facilitators of nurse identification and referral of patients with depressive symptoms as part of integrated mental health service delivery in KwaZulu-Natal, South Africa. Read More

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December 2021

Changes in Community Clinicians' Attitudes and Competence following a Transdiagnostic Cognitive Behavioral Therapy Training.

Implement Res Pract 2021 Jan 15;2. Epub 2021 Jul 15.

National Center for PTSD and Stanford University, 795 Willow Road NC-PTSD, Menlo Park, CA, 94025, USA.

Background: Although the literature suggest that attitudes toward evidence-based practices (EBPs) are associated with provider use of EBPs, less is known about the association between attitudes and how competently EBPs are delivered. This study examined how initial attitudes and competence relate to improvements in attitudes and competence following EBP training.

Methods: Program evaluation data was collected during implementation of an EBP in a large community mental health network. Read More

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January 2021

Does Fit Mean (f)it? A Comparison of Physiological and Experiential Fitness Data From the iReAct Study.

Front Sports Act Living 2021 1;3:729090. Epub 2021 Sep 1.

Department of Social and Public Health Sciences, Institute of Sport Science, Eberhard Karls University Tübingen, Tübingen, Germany.

Regular exercise fosters fitness-enhancing benefits. We assume that exercise interventions become successful and sustainable if physiological benefits of exercise are also subjectively perceivable. The goal of this study was to examine how young inactive adults to an exercise intervention and how those responses are . Read More

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September 2021

Machine learning for identification of frailty in Canadian primary care practices.

Int J Popul Data Sci 2021 10;6(1):1650. Epub 2021 Sep 10.

Cumming School of Medicine, University of Calgary.

Introduction: Frailty is a medical syndrome, commonly affecting people aged 65 years and over and is characterized by a greater risk of adverse outcomes following illness or injury. Electronic medical records contain a large amount of longitudinal data that can be used for primary care research. Machine learning can fully utilize this wide breadth of data for the detection of diseases and syndromes. Read More

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September 2021