87,147 results match your criteria traffic

Effects of short-term personal exposure to air pollution on platelet mitochondrial DNA methylation levels and the potential mitigation by L-arginine supplementation.

J Hazard Mater 2021 Apr 29;417:125963. Epub 2021 Apr 29.

Department of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China. Electronic address:

The potential effect of short-term exposure to air pollution on mitochondrial DNA (mtDNA) methylation remains to be explored. This study adopted an experimental exposure protocol nested with an intervention study on L-arginine (L-Arg) supplementation among 118 participants. Participants walked along a traffic road for 2 hours in the last day of a 14-day intervention to investigate the effects of short-term personal exposure to air pollution on platelet mtDNA methylation and the possible modifying effects of L-Arg supplementation. Read More

View Article and Full-Text PDF

Spatio-temporal changes of road traffic noise pollution at ecoregional scale.

Environ Pollut 2021 May 4;286:117291. Epub 2021 May 4.

Universidad Politécnica de Madrid, Madrid, Spain.

Noise pollution is a pervasive factor that increasingly threatens natural resources and human health worldwide. In particular, large-scale changes in road networks have driven shifts in the acoustic environment of rural landscapes during the past few decades. Using sampling plots from the Spanish Landscape Monitoring System (SISPARES), 16 km each, we modelled the spatio-temporal changes in road traffic noise pollution in Ecoregion 1 of Spain (approximately 66,000 km). Read More

View Article and Full-Text PDF

Formulating a GIS-based geometric design quality assessment model for Mountain highways.

Accid Anal Prev 2021 May 10;157:106172. Epub 2021 May 10.

School of Engineering, RMIT University, Melbourne, 3000, Victoria, Australia. Electronic address:

Highways play an important role in China's economic development, especially in mountainous regions. In reality, design of mountainous highways can be a challenging task due to complex geological and topographic conditions. From the safety perspective, it is also important that road geometric design defects and potential accident blind spots can be reasonably identified from the design. Read More

View Article and Full-Text PDF

Mining patterns of near-crash events with and without secondary tasks.

Accid Anal Prev 2021 May 11;157:106162. Epub 2021 May 11.

Zachry Department of Civil & Environmental Engineering, Texas A&M University, 3136 TAMU, College Station, TX, 77843-3136, United States. Electronic address:

The engagement of secondary tasks, like using a phone or talking to passengers while driving, could introduce considerable risks to driving safety. This study utilizes a near-crash dataset extracted from a naturalistic driving study to explore the patterns of near-crash events with or without the involvement of secondary tasks as a surrogate approach to understand the impact of these behaviors on traffic safety. The dataset contains information about driver behaviors, such as secondary tasks, vehicle maneuvers, other conflict vehicles' maneuvers before and during near-crash events, and the driving environment. Read More

View Article and Full-Text PDF

Knockdown of miR-26a in Zebrafish Leads to Impairment of the Anti-Inflammatory Function of TnP in the Control of Neutrophilia.

Fish Shellfish Immunol 2021 May 10. Epub 2021 May 10.

Immunoregulation Unit of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, Vital Brazil Avenue, 1500. Butantan, 05503-009. São Paulo. Brazil.

Our recent data show the valuable potential of TnP for the development of a new and safe anti-inflammatory drug due to its ability to control the traffic and activation of leukocytes in response to inflammation. Although there is considerable knowledge surrounding the cellular mechanisms of TnP, less is known about the mechanistic molecular role of TnP underlying its immunomodulatory functions. Here, we conducted investigations to identify whether miRNAs could be one of the molecular bases of the therapeutic effect of TnP. Read More

View Article and Full-Text PDF

ToxChip PCR Arrays for Two Arctic-Breeding Seabirds: Applications for Regional Environmental Assessments.

Environ Sci Technol 2021 May 13. Epub 2021 May 13.

National Wildlife Research Centre, Environment and Climate Change Canada, 1125 Colonel By Dr., Ottawa, ON ON K1S, Canada.

Increasing pollution in the Arctic poses challenges in terms of geographical and ecological monitoring. The Baffin Bay-Davis Strait (BBDS) region in the Canadian Arctic Archipelago is of particular concern due to the potential for increased shipping traffic and oil exploration. However, data on background contaminants associated with oil exploration/spills/natural seeps (e. Read More

View Article and Full-Text PDF

Automatic traffic monitoring by -OTDR data and Hough transform in a real-field environment.

Appl Opt 2021 May;60(13):3579-3584

In this paper, we demonstrate automatic vehicle detection and counting by processing data acquired using a phase-sensitive optical time-domain reflectometer (-OTDR) distributed optical fiber sensor. The acquired data are processed using the Hough transform, which detects the lines in the images formed by representing the acquired data in the space-time domain. A rough classification of the vehicles (heavy versus light vehicles) is also proposed, based on the amplitude of the vibration data along the detected lines. Read More

View Article and Full-Text PDF

Thermal Hysteresis Involving Reversible Self-Catalytic Reactions.

Acc Chem Res 2021 May 13. Epub 2021 May 13.

State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China.

ConspectusHysteresis is ubiquitous in nature and biology. It appears in ferromagnetism, ferroelectrism, traffic congestion, river sedimentation, electronics, thermoresponses, cell division, differentiation, and apoptosis. Hysteresis phenomena are beyond equilibrium and involve nonlinear, bistable, time delay, and memory events, which are described in input/output profiles by different outputs during continuous decreases and increases in input intensity. Read More

View Article and Full-Text PDF

Primary Trauma Care Course: Alternative Basic Trauma Course In Developing Countries. "The Need Of The Hour."

Int J Clin Pract 2021 May 12:e14327. Epub 2021 May 12.

Ziauddin Medical University, Karachi, Pakistan.

Objective: Low and middle-income countries account for over 90% of all road traffic injury deaths. Despite this, formal training in trauma management is not widely adopted in these countries.No specific training was available in prehospital or emergency department for life support before Primary Trauma Care (PTC) course. Read More

View Article and Full-Text PDF

ST-AFN: a spatial-temporal attention based fusion network for lane-level traffic flow prediction.

PeerJ Comput Sci 2021 22;7:e470. Epub 2021 Apr 22.

College of Computer Science and Technology, Zhejiang University of Technology, Hangzhou, China.

Traffic flow prediction is the foundation of many applications in smart cities, and the granular precision of traffic flow prediction has to be enhanced with refined applications. However, most of the existing researches cannot meet these requirements. In this paper, we propose a spatial-temporal attention based fusion network (ST-AFN), for lane-level precise prediction. Read More

View Article and Full-Text PDF

Means of intracellular communication: touching, kissing, fusing.

Anne Spang

Microb Cell 2021 Apr 13;8(5):87-90. Epub 2021 Apr 13.

Biozentrum, University of Basel, Klingelbergstrasse 70, CH-4056 Basel, Switzerland.

Eukaryotic cells are complicated factories that need ensure productivity and functionality on the cellular level as well as being able to communicate with their environment. In order to do so cells developed intracellular communication systems. For a long time, research focused mainly on the secretory/biosynthetic and endocytic routes for communication, leaving the communication with other organelles apart. Read More

View Article and Full-Text PDF

Health Lens Analysis: A Strategy to Engage Community in Environmental Health Research in Action.

Sustainability 2021 Feb 6;13(4). Epub 2021 Feb 6.

Macro Department, Boston University School of Social Work, 264 Bay State Rd., Boston, MA 02215, USA.

Health Lens Analysis is a tool to facilitate collaboration among diverse community stakeholders. We employed HLA as part of a community based participatory research (CBPR) and action study to mitigate the negative health effects of TRAP and ultrafine particles (UFPs) in Somerville, MA. HLA is a Health in All Policies tool with previously limited implementation in a North American context. Read More

View Article and Full-Text PDF
February 2021

Dynein light chain Dynlrb2 is essential for Murine leukemia virus traffic and nuclear entry.

J Virol 2021 May 12. Epub 2021 May 12.

Instituto de Ciencias Biomédicas, Facultad de Medicina y Facultad de Ciencias de la Vida, Universidad Andrés Bello, Chile

Murine leukemia virus (MLV) requires the infected cell to divide to access the nucleus to integrate into the host genome. It has been determined that MLV uses the microtubule and actin network to reach the nucleus at the early stages of infection. Several studies have shown that viruses use the dynein motor protein associated with microtubules for their displacement. Read More

View Article and Full-Text PDF

Endogenous and Borrowed Proteolytic Activity in the .

Microbiol Mol Biol Rev 2021 May 12;85(2). Epub 2021 May 12.

Department of Microbiology and Immunology, Stony Brook University, Stony Brook, New York, USA

SUMMARYThe spp. are tick-borne pathogenic spirochetes that include the agents of Lyme disease and relapsing fever. As part of their life cycle, the spirochetes traffic between the tick vector and the vertebrate host, which requires significant physiological changes and remodeling of their outer membranes and proteome. Read More

View Article and Full-Text PDF

Traffic noise disrupts vocal development and suppresses immune function.

Sci Adv 2021 May 12;7(20). Epub 2021 May 12.

Max Planck Institute for Ornithology, Communication and Social Behaviour Group, Seewiesen, Germany.

Noise pollution has been linked to learning and language deficits in children, but the causal mechanisms connecting noise to cognitive deficiencies remain unclear because experimental models are lacking. Here, we investigated the effects of noise on birdsong learning, the primary animal model for vocal learning and speech development in humans. We found that traffic noise exposure retarded vocal development and led to learning inaccuracies. Read More

View Article and Full-Text PDF

Trends in Propeller Strike-Induced Mortality in Harbor Seals (Phoca vitulina) of the Salish Sea.

J Wildl Dis 2021 May 12. Epub 2021 May 12.

SeaDoc Society, UC Davis Karen C. Drayer Wildlife Health Center-Orcas Island Office, 942 Deer Harbor Road, Eastsound, Washington 98245, USA.

Documenting human impacts on marine mammals is critical for understanding and mitigating harm. Although propeller strike injuries in small marine mammals are often debilitating and fatal, little is known about the occurrence or demographics of these types of injuries in pinniped populations. Using data of stranded harbor seals (Phoca vitulina) in the Salish Sea from 2002-19, we identified 27 cases of fatal propeller strikes. Read More

View Article and Full-Text PDF

The impact of mass drug administration expansion to low onchocerciasis prevalence settings in case of connected villages.

PLoS Negl Trop Dis 2021 May 12;15(5):e0009011. Epub 2021 May 12.

Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Background: The existence of locations with low but stable onchocerciasis prevalence is not well understood. An often suggested yet poorly investigated explanation is that the infection spills over from neighbouring locations with higher infection densities.

Methodology: We adapted the stochastic individual based model ONCHOSIM to enable the simulation of multiple villages, with separate blackfly (intermediate host) and human populations, which are connected through the regular movement of the villagers and/or the flies. Read More

View Article and Full-Text PDF

Modeling the influence of 0.03%, 0.05% and 0.08% blood alcohol concentrations on lane positioning and steering control of Indian drivers.

Traffic Inj Prev 2021 May 12:1-11. Epub 2021 May 12.

Transportation Systems Engineering, Department of Civil Engineering, Indian Institute of Technology (IIT) Bombay, Mumbai, Maharashtra, India.

Objective: Alcohol-impairment of drivers has significant influence on road traffic safety; however, no experimental research has been conducted on the lateral driving control of Indian drivers. Therefore, the present study investigates the effects of different Blood Alcohol Concentration (BAC) levels (0%, 0.03%, 0. Read More

View Article and Full-Text PDF

Air quality in cabin environment of different passenger cars: effect of car usage, fuel type and ventilation/infiltration conditions.

Environ Sci Pollut Res Int 2021 May 12. Epub 2021 May 12.

Department of Mechanical Engineering, Environmental Technology Laboratory, University of Western Macedonia, Sialvera & Bakola Street, 50100, Kozani, Greece.

Despite that commuters spend only 5.5% of their time in cabin vehicles, their exposure to harmful air pollutants, originated from the vehicle itself, and traffic emission is considered significant. In this study, two passenger cars with different type of fuels were investigated in terms of air quality and thermal comfort of their cabin. Read More

View Article and Full-Text PDF

Toxicological Impacts of Roadway Deicers on Aquatic Resources and Human Health: A Review.

Water Environ Res 2021 May 12. Epub 2021 May 12.

Department of Civil & Environmental Engineering, Washington State University, P. O. Box 642910, Pullman, WA, 99164-2910, USA.

During winter, snow and ice on roads in regions with cold weather can increase traffic crashes and casualties, resulting in travel delays and financial burdens to society. Anti-icing or deicing the roads can be a cost-effective method to significantly reduce such risks. Although traditionally the main priorities of winter road maintenance (WRM) have been level of service, cost-effectiveness, and corrosion, it is increasingly clear that understanding the environmental impacts of deicers is vital. Read More

View Article and Full-Text PDF

Exomer complex regulates protein traffic at the TGN through differential interactions with cargos and clathrin adaptor complexes.

FASEB J 2021 Jun;35(6):e21615

Instituto de Biología Funcional y Genómica (IBFG) and Departamento de Microbiología y Genética, CSIC-Universidad de Salamanca, Salamanca, Spain.

Protein sorting at the trans-Golgi network (TGN) usually requires the assistance of cargo adaptors. However, it remains to be examined how the same complex can mediate both the export and retention of different proteins or how sorting complexes interact among themselves. In Saccharomyces cerevisiae, the exomer complex is involved in the polarized transport of some proteins from the TGN to the plasma membrane (PM). Read More

View Article and Full-Text PDF

Performance and perception on front-of-package nutritional labeling models in Brazil.

Rev Saude Publica 2021 10;55:19. Epub 2021 May 10.

Universidade de Brasília. Faculdade de Ciências da Saúde. Programa de Pós-Graduação em Saúde Coletiva. Asa Norte, Campus Universitário Darcy Ribeiro, Brasília, DF, Brasil.

Objective: To evaluate the performance and perception of five models of front-of-package nutrition labeling (FOPNL) among Brazilian consumers.

Methods: Cross-sectional study, which applied an online questionnaire to 2,400 individuals, allocated randomly into six study groups: a control group and five others exposed to FOPNL (octagon, triangle, circle, magnifier and traffic light), applied to nine products. We evaluated the understanding of nutritional content, the perception of healthiness, the purchase intention and the perception of Brazilian consumers on the models. Read More

View Article and Full-Text PDF

Overall health impacts of a potential increase in cycle commuting in Stockholm, Sweden.

Scand J Public Health 2021 May 12:14034948211010024. Epub 2021 May 12.

Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

Aims: To estimate the overall health impact of transferring commuting trips from car to bicycle.

Methods: In this study registry information on the location of home and work for residents in Stockholm County was used to obtain the shortest travel route on a network of bicycle paths and roads. Current modes of travel to work were based on travel survey data. Read More

View Article and Full-Text PDF

AQI time series prediction based on a hybrid data decomposition and echo state networks.

Hui Liu Xinyu Zhang

Environ Sci Pollut Res Int 2021 May 12. Epub 2021 May 12.

Institute of Artificial Intelligence and Robotics (IAIR), Key Laboratory of Traffic Safety on Track of Ministry of Education, School of Traffic and Transportation Engineering, Central South University, Changsha, 410075, Hunan, China.

A hybrid AQI time series prediction model is proposed based on EWT-SE-VMD secondary decomposition, ICA (imperialist competitive algorithm) feature selection, and ESN (echo state network) neural network. Firstly, EWT (empirical wavelet transform) and VMD (variational mode decomposition) are used to decompose the original AQI time series into several stable and reliable subseries. Then, the ICA is used to select features of the above subseries for the ESN prediction model. Read More

View Article and Full-Text PDF

Simulation of Transit Transportation along the Northern Sea Route under Climate Change.

Stud Russ Econ Dev 2021 6;32(2):160-168. Epub 2021 May 6.

Federal Research Center "Computer Science and Control", Russian Academy of Sciences, 119333 Moscow, Russia.

The article examines the problems and development prospects for the international transit of goods along the NSR. The existing restrictions on increasing freight traffic up to 80 million tons per year declared in program documents are identified. An option for its enhancement based on the domestic fleet of Arctic cargo ships is proposed. Read More

View Article and Full-Text PDF

Inositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites.

Nat Commun 2021 May 11;12(1):2673. Epub 2021 May 11.

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.

Vesicular traffic and membrane contact sites between organelles enable the exchange of proteins, lipids, and metabolites. Recruitment of tethers to contact sites between the endoplasmic reticulum (ER) and the plasma membrane is often triggered by calcium. Here we reveal a function for calcium in the repression of cholesterol export at membrane contact sites between the ER and the Golgi complex. Read More

View Article and Full-Text PDF

Functional assessment of driving capacity in older drivers in comparison with non-older drivers using clinical evaluation and driving simulation.

Ann Geriatr Med Res 2021 May 12. Epub 2021 May 12.

Department of smart mechanical automotive engineering, Changwon Moonsung University, 91, Chunghon-ro, Uichang-gu, Changwon-si, Gyeongsangnam-do, 51410, South Korea.

Background: This study aimed to examine various tools (self-assessment questionnaire, the Clinical Assessment of Driver-Related Skills (CADReS), and a driving simulation) to discriminate between older and non-older drivers capacity. .

Methods: We evaluated driving habits, driving-related health behaviors, and morbidities by a self-assessment questionnaire and assessed visual, motor, and cognitive functions using the CADReS and a vehicle simulator run on four junction scenarios being typical of accidents involving older drivers. Read More

View Article and Full-Text PDF

A data-driven approach to strengthening policies to prevent freeway tunnel strikes by motor vehicles.

Accid Anal Prev 2021 May 8;157:106171. Epub 2021 May 8.

University of Wisconsin-Milwaukee, Department of Civil and Environmental Engineering, NWQ4414, P.O. Box 784, Milwaukee, WI, 53201, United States. Electronic address:

Freeway tunnel strikes by motor vehicles inflict serious damages to the infrastructure, cause personal injuries, and create traffic congestions. Freeway tunnel hits are a constant threat in South Korea due to its mostly mountainous terrain. Despite efforts by public agencies to include disaster remedial or preventative facilities in the development of freeway tunnels, these facilities are designed mainly to reduce the number of collisions instead of also mitigate the consequences of a crash. Read More

View Article and Full-Text PDF

Estimating safety performance functions for two-lane rural roads using an alternative functional form for traffic volume.

Accid Anal Prev 2021 May 8;157:106173. Epub 2021 May 8.

Department of Civil and Environmental Engineering, The Pennsylvania State University, 231 Sackett Building, University Park, PA, 16802, United States. Electronic address:

Statistical models of expected crash frequency are referred to as Safety Performance Functions (SPFs) in the first edition of the American Association of State Highway and Transportation Officials' Highway Safety Manual (HSM). The SPFs in the HSM specify expected annual crash frequencies as a function of various roadway and roadside features, with the most important predictor variable being traffic volume, which serves as a measure of vehicle exposure to crashes. Traffic volumes are typically measured using the average annual daily traffic and are incorporated into the SPFs using a natural logarithm transformation. Read More

View Article and Full-Text PDF

A review of surrogate safety measures and their applications in connected and automated vehicles safety modeling.

Accid Anal Prev 2021 May 8;157:106157. Epub 2021 May 8.

School of Transportation, Southeast University, China. Electronic address:

Surrogate Safety Measures (SSM) are important for safety performance evaluation, since crashes are rare events and historical crash data does not capture near crashes that are also critical for improving safety. This paper focuses on SSM and their applications, particularly in Connected and Automated Vehicles (CAV) safety modeling. It aims to provide a comprehensive and systematic review of significant SSM studies, identify limitations and opportunities for future SSM and CAV research, and assist researchers and practitioners with choosing the most appropriate SSM for safety studies. Read More

View Article and Full-Text PDF