7,966 results match your criteria tracheal stenosis


Clinical application of PEAK PlasmaBlade to remove distal tracheal granulation in patients after tracheostomy.

Auris Nasus Larynx 2021 Jul 22. Epub 2021 Jul 22.

Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou Medical Center, 5, Fu-shin street, Kweishan 333, Taoyuan, Taiwan; School of Medicine, Chang Gung University, Taoyuan, Taiwan.

Objective: Tracheal granulation is one of the common long term complications in patients after tracheostomy. Hypertrophic tracheal granulation may cause airway obstruction and further operation may be required to recreate an airway. Distal tracheal granulation is clinically challenging because of its position and surgical field limitation. Read More

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Plumbagin attenuates traumatic tracheal stenosis in rats and inhibits lung fibroblast proliferation and differentiation via TGF-β1/Smad and Akt/mTOR pathways.

Bioengineered 2021 Dec;12(1):4475-4488

Pulmonary and Critical Care Medicine of The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Traumatic tracheal stenosis (TS) is a serious respiratory disease characterized by hyperplasia of airway granulation. Plumbagin (PLB) is a natural naphthoquinone component with anti-fibrotic properties. This research aimed to explore the roles of PLB in alleviating TS and the underlying mechanisms. Read More

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December 2021

[Perioperative airway management of infantile subglottic hemangioma].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Jun;35(6):501-504;510

Department of Anesthesiology,Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine.

To investigate the relevant influencing factors for perioperative airway events of infantile subglottic hemangioma, and to further discuss the strategies of perioperative airway management. A total of 36 infants with subglottic hemangioma that had no response to the drug therapy and underwent surgical treatment from July 2007 to April 2017 were enrolled. The relevant influencing factors, including gender, age, birth weight, age of onset, degree of tracheal stenosis and histories of underlying diseases(congenital heart disease and respiratory disease), were also recorded simultaneously. Read More

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Segmental congenital deficiency of tracheal rings in cervical trachea managed by tracheal resection: A case report and literature review.

Int J Pediatr Otorhinolaryngol 2021 Jul 17;148:110844. Epub 2021 Jul 17.

Division of Pediatric Otorhinolaryngology, Karolinska University Hospital, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.

Congenital deficiency of tracheal rings in the cervical trachea is a rare anomaly and only one case has previously been reported in the literature (Wineland et al., 2017) [1]. Here we report a case in a newborn female transferred to our department at 11 weeks of age for management of stridor. Read More

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Tracheal window resection and reconstruction via sternocleidomastoid flap for invasive thyroid carcinoma.

Interact Cardiovasc Thorac Surg 2021 Jul 19. Epub 2021 Jul 19.

Department of Otolaryngology-Head and Neck Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

Objectives: The aim of this study was to present surgical techniques and evaluate outcomes of a sternocleidomastoid muscle (SCM) myoperiosteal flap used for the reconstruction of tracheal or laryngotracheal defects after the radical resection of invasive thyroid carcinoma.

Methods: A retrospective study was performed for patients at Peking Union Medical College Hospital from January 2008 to December 2018 of papillary thyroid carcinoma with tracheal or laryngotracheal invasion. Patients were enrolled only when they received window resection and reconstruction via an SCM myoperiosteal flap. Read More

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Slide Tracheoplasty for Congenital Tracheal Stenosis Repair: A Systematic Review and Meta-Analysis.

Laryngoscope 2021 Jul 20. Epub 2021 Jul 20.

Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, National Clinical Research Center for Child Health and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, China.

Objectives: Congenital tracheal stenosis (CTS) is a rare but life-threatening condition in children. At present, slide tracheoplasty has been advocated as the preferred technique for most cases of CTS. However, the morbidity and mortality subsequent to slide tracheoplasty need further elaboration. Read More

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Extracorporeal life support as a lifesaving procedure in palliative surgery of stenosing upper tracheal tumor.

Ann Card Anaesth 2021 Jul-Sep;24(3):389-391

Department of Cardiovascular Surgery, University Hospital of Clermont-Ferrand, France.

In the patients with stenotic upper respiratory airways tumor, the tracheal intubation during the surgical resection is sometimes impossible. In these situations, Extracorporeal Membrane Oxygenation appears to be an interesting temporarily alternative to ventilation to allow tumor removal. In this report the authors describe a case of successful resection of tracheal tumor in an 80-year-old female patient in which tracheal intubation was impossible. Read More

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Asphyxia caused by delayed subglottic stenosis after neck trauma.

Forensic Sci Med Pathol 2021 Jul 14. Epub 2021 Jul 14.

Department of Forensic Medicine, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.

Delayed subglottic stenosis (SGS) is an unusual complication. Here, we report a particular case of delayed SGS. A 17-year-old female suffered extensive injuries including severe neck trauma in a car accident, and complained of dyspnea after 30 days. Read More

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Tracheobronchial amyloidosis: A case report and review of literature.

Radiol Case Rep 2021 Sep 1;16(9):2399-2403. Epub 2021 Jul 1.

Department of Radiology, West Virginia University, Morgantown, WV.

Tracheobronchial amyloidosis, manifested by amyloid deposits limited specifically to tracheal and bronchial tissue, is a rare manifestation with only a few hundred published cases. Patients classically present with symptoms related to fixed upper airway obstruction caused by tracheal stenosis. Clinical symptoms are non-specific and include hoarseness, dyspnea, cough, stridor, hemoptysis, and dysphagia, which are similar to those caused by more common airway disorders, often leading to incorrect, missed, and delayed diagnosis. Read More

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September 2021

Incidence and risk factor of vocal cord paralysis following slide tracheoplasty for congenital tracheal stenosis: a retrospective observational study.

Cardiol Young 2021 Jul 12:1-5. Epub 2021 Jul 12.

Department of Pediatric Critical Care Medicine, Hyogo Prefectural Kobe Children's Hospital, Kobe, Hyogo, Japan.

Background: Slide tracheoplasty for congenital tracheal stenosis (CTS) has been shown to improve post-operative outcomes, but the incidence and risk factors of vocal cord paralysis (VCP) following slide tracheoplasty remain unclear. This study aimed to review our experience of slide tracheoplasty for CTS with a focus on post-operative VCP.

Methods: Twenty-eight patients, who underwent tracheal reconstruction with or without cardiovascular repair at Kobe Children's Hospital between June, 2016 and March, 2020 were enrolled in this retrospective observational study. Read More

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Cervical Disorders in Mucopolysaccharidosis IVA-Morquio disease.

World Neurosurg 2021 Jul 8;153:41-43. Epub 2021 Jul 8.

Complexo Hospital de Clínicas, Universidade Federal do Parana, Curitiba, Brazil.

Morquio disease or mucopolysaccharidosis type IVA (Online Mendelian Inheritance in Man No. 253000) is a rare autosomal recessive disease classified in the group of metabolism inborn errors. The glycosaminoglycans accumulate in chondrocytes, which disturbs bone growth and leads to skeletal manifestations, such as skeletal dysplasia and a short stature. Read More

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Protective effects of different anti‑inflammatory drugs on tracheal stenosis following injury and potential mechanisms.

Mol Med Rep 2021 May 9;23(5). Epub 2021 Jul 9.

Department of Respiratory Medicine, Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530007, P.R. China.

Tracheal stenosis following injury cannot be effectively treated. The current study compared the protective effects of different anti‑inflammatory drugs on tracheal stenosis and investigated their possible mechanisms. Rabbit tracheal stenosis models following injury were constructed and confirmed using hematoxylin and eosin (H&E) staining. Read More

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Extracorporeal membrane oxygenation for the anesthetic management of a patient with severe airway stenosis caused by thyroid carcinoma invasion.

Surg Today 2021 Jul 7. Epub 2021 Jul 7.

Department of Cardiovascular Medicine, International University of Health and Welfare, Atami Hospital, 13-1 Higashikaigan-cho, Atami-City, Shizuoka, 413-0012, Japan.

The treatment of a thyroid carcinoma extending into the thoracic cavity with severe airway stenosis is difficult, since there is a risk of acute respiratory decompensation at every stage of anesthesia. Extracorporeal membrane oxygenation (ECMO) is a life support technique for maintaining both the cardiac and respiratory functions. It is used for the management of acute, severe, reversible respiratory or cardiac failure refractory to conventional management. Read More

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Case reports of one-lung ventilation using Fuji Uniblocker bronchial blockers for infants under one-year-old in uniportal video-assisted thoracoscopic surgery.

Medicine (Baltimore) 2021 Jul;100(27):e26325

Department of Anesthesiology, Taichung Veterans General Hospital, Taichung.

Introduction: Uniportal video-assisted thoracoscopic surgery (VATS) for various pulmonary diseases provides advantages of less postoperative pain and earlier post-operative recovery over traditional open surgery. The inherent limitation of this surgical modality in manipulation of surgical instruments renders intra-operative one-lung ventilation a requisite to increase the substantially restricted working space and thus visibility of the surgical filed.

Patient Concerns: Patient 1, an 8-month-old, 9-kg, and 70 cm-in-height male infant was diagnosed as congenital pulmonary airway malformation (CPAM) over left lower lobe. Read More

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Antibacterial and antihyperplasia polylactic acid/silver nanoparticles nanofiber membrane-coated airway stent for tracheal stenosis.

Colloids Surf B Biointerfaces 2021 Jun 29;206:111949. Epub 2021 Jun 29.

Department of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450001, China. Electronic address:

Antibacterial and antihyperplasia airway stents are highly desirable for tracheal stenosis. Herein, a series of polylactic acid (PLA) and silver nanoparticles (AgNPs) nanofiber membranes (PLA, PLA-4 %AgNPs and PLA-6 % AgNPs) were prepared by electrospinning. The physicochemical and biological properties of the resultant nanofiber membranes were examined. Read More

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The Role of Lung Function Testing in Newborn Infants With Congenital Thoracic Arterial Anomalies.

Front Pediatr 2021 15;9:682551. Epub 2021 Jun 15.

Neonatal Intensive Care Unit, Medical and Surgical Department of Fetus, Newborn and Infant-"Bambino Gesù" Children's Hospital IRCCS, Rome, Italy.

Congenital thoracic arterial anomalies (CTAAs), such as complete or incomplete vascular rings, pulmonary artery sling, and innominate artery compression syndrome, may cause severe tracheomalacia and upper airway obstruction. An obstructive ventilatory pattern at lung function testing (LFT) has been suggested in the presence of CTAA. The severity of obstruction may be evaluated by LFT. Read More

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A case of double aortic arch with tracheal stenosis and its anaesthetic management.

Indian J Anaesth 2021 May 20;65(5):408-409. Epub 2021 May 20.

Department of Cardiac Anaesthesia, U. N. Mehta Institute of Cardiology and Research Centre, Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat, India.

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A tracheobronchial adenoid cystic carcinoma incidentally detected by chest radiography and pulmonary function test.

Adv Respir Med 2021 ;89(3):320-323

Department of Thoracic Surgery, Tokyo Medical University Ibaraki Medical Center, Ami-machi, Ibaraki, Japan.

Tracheobronchial adenoid cystic carcinomas are rare tumors that progress slowly. Diagnosis by chest plain radiography is difficult, and suspecting the existence of a disease that causes stenosis in the airways is an important key for diagnosis. A 51-year-old woman referred to our hospital because of dyspnea on exertion. Read More

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January 2021

Replacement of a 5-cm intrathoracic trachea with a tissue-engineered prosthesis in a canine model.

Ann Thorac Surg 2021 Jun 26. Epub 2021 Jun 26.

Department of Thoracic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Background: Critical obstacles must be addressed before clinical application of artificial tracheas. The major complications of long tracheal replacement include anastomotic dehiscence and stenosis owing to poor vascularity and incomplete re-epithelialization. The objective of this report was to clarify whether pre-incubation of the prosthesis in the omentum could be applicable for reconstruction of a long segment of the intrathoracic trachea in a canine model. Read More

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Particulate matter 2.5 triggers airway inflammation and bronchial hyperresponsiveness in mice by activating the SIRT2-p65 pathway.

Front Med 2021 Jun 28. Epub 2021 Jun 28.

Department of Cardiovascular Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.

Exposure to particulate matter 2.5 (PM2.5) potentially triggers airway inflammation by activating nuclear factor-κB (NF-κB). Read More

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Definitive carbon ion radiotherapy for tracheobronchial adenoid cystic carcinoma: a preliminary report.

BMC Cancer 2021 Jun 26;21(1):734. Epub 2021 Jun 26.

Shanghai Key Laboratory of Radiation Oncology, Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai, 201321, China.

Background: Tracheobronchial adenoid cystic carcinoma (TACC) is a rare tumour. About one-third of patients miss their chance of surgery or complete resection as it is mostly detected in the advanced stage; hence, photon radiotherapy (RT) is used. However, the outcomes of photon RT remain unsatisfactory. Read More

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Acquired tracheal stenosis: Cervical slide tracheoplasty.

Semin Pediatr Surg 2021 Jun 25;30(3):151058. Epub 2021 May 25.

Division of Pediatric Otolaryngology - Head and Neck Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Otolaryngology - Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Acquired tracheal stenosis can result from iatrogenic injury or, less commonly, tracheal tumors. Symptoms can arise insidiously and typically include respiratory distress, sleep disordered breathing, or exercise intolerance. Diagnostic evaluation includes cross-sectional imaging and endoscopy. Read More

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Working as a team in airway surgery: History, present and perspectives.

Semin Pediatr Surg 2021 Jun 21;30(3):151051. Epub 2021 May 21.

Airway Team of IRCCS Giannina Gaslini, Genova, Italy.

Teamwork is one of the most important trend in modern medicine. Airway team were created in many places to respond in a multidisciplinary and coordinated way to challenging clinical problems which were beyond the possibility of an individual management. In this chapter, we illustrate the historical steps leading to the development of an airway team in a pediatric referral hospital, describe the present teamwork activity defining the key points for the creation of a team and discussing different organization models; finally we delineate possible future directions for the airway teams in the globalized world. Read More

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Congenital airway anomalies.

Semin Pediatr Surg 2021 Jun 23;30(3):151055. Epub 2021 May 23.

Pediatric ENT, Hospital De Clinicas de Porto Alegre, Porto Alegre, Brazil.

Congenital airway anomalies (CAA) include a variety of conditions that cause respiratory distress in neonates and infants. These malformations occur at various anatomic levels and manifest in a wide spectrum of airway symptoms, with presentation significantly influenced by the level at which obstruction occurs as well as by the severity of obstruction. The prevalence of congenital airway malformations has been estimated to range between 0. Read More

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Complex tracheal resection in children: Myths, reality and lessons learned.

Semin Pediatr Surg 2021 Jun 23;30(3):151059. Epub 2021 May 23.

Division of Pediatric Surgery, Pediatric Airway and Chest Wall Center, Hospital de Niños Luis Calvo Mackenna, University of Chile, Santiago, Chile.

Tracheal resection is an uncommon procedure in children. It was described many years ago and many surgeons still rely on historical reports when performing the procedure, despite the technological and clinical advancements achieved during the last decades. We consider complex tracheal resections those resections of 30 to 50% of tracheal length, corresponding to at least 6-7 rings. Read More

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Risk factors for anastomotic complications after one-stage anastomosis for oesophageal atresia.

J Cardiothorac Surg 2021 Jun 19;16(1):176. Epub 2021 Jun 19.

Department of Cardiothoracic Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China.

Background: Oesophageal atresia is a congenital malformation of the oesophagus and a serious malformation of the digestive system, postoperative complications include acute respiratory failure, pneumonia, anastomotic fistula, anastomotic stenosis, tracheal stenosis, gastroesophageal reflux and eosinophilic oesophagitis, anastomotic fistula is one of the important causes of postoperative death. The objective of this study is to identify the risk factors for anastomotic complications after one-stage anastomosis for oesophageal atresia.

Methods: A retrospective analysis was performed on the clinical data of 107 children with congenital oesophageal atresia who underwent one-stage anastomosis in our hospital from January 2013 to December 2018. Read More

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Multilevel Airway Stenosis Being Bypassed by a Customized Tracheostomy Tube in an Infant with Myhre Syndrome.

Pediatr Allergy Immunol Pulmonol 2021 Jun;34(2):83-87

Department of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, Korea.

Myhre syndrome is a rare connective tissue disorder caused by heterozygous pathogenic variants in the gene. Although recognizing Myhre syndrome in early childhood is challenging, it is important to manage airway stenosis in patients with Myhre syndrome. We report the case of a 2-month-old boy who initially presented with severe multilevel airway stenosis, dysmorphic face, and multiple abnormalities. Read More

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Identifying Phenotypically Distinct Fibroblast Subsets in Type 2 Diabetes-Associated Iatrogenic Laryngotracheal Stenosis.

Otolaryngol Head Neck Surg 2021 Jun 15:1945998211014790. Epub 2021 Jun 15.

Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

Objective: Iatrogenic laryngotracheal stenosis (iLTS) is the pathologic narrowing of the glottis, subglottis, and/or trachea secondary to intubation or tracheostomy related injury. Patients with type 2 diabetes mellitus (T2DM) are more likely to develop iLTS. To date, the metabolomics and phenotypic expression of cell markers in fibroblasts derived from patients with T2DM and iLTS are largely unknown. Read More

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ECMO Rescues Patients With Acute Respiratory Failure Related to GPA.

Front Med (Lausanne) 2021 28;8:671396. Epub 2021 May 28.

Department of Respiratory Medicine (Department of Respiratory and Critical Care Medicine), Xiangya Hospital, Central South University, Changsha, China.

Granulomatosis with polyangiitis (GPA) is a subtype of anti-neutrophil cytoplasmic antibody-associated vasculitis with a wide range of clinical symptoms related to the systemic involvement of small blood vessels. The respiratory system is one of the most frequently involved, and life-threatening acute respiratory failure could occur due to diffusive alveolar hemorrhage and tracheal stenosis. When maximum mechanical ventilation is unable to maintain oxygenation, extracorporeal membrane oxygenation (ECMO) should be considered as the final respiratory supportive method, if available. Read More

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Post-intubation tracheal stenosis after severe COVID-19 infection: A report of two cases.

Ann Med Surg (Lond) 2021 Jul 9;67:102468. Epub 2021 Jun 9.

Department of Thoracic Surgery, Al-Mouassat University Hospital, Damascus, Syrian Arab Republic.

Introduction And Importance: Coronavirus disease 2019 (COVID-19) is a pandemic disease that spread rapidly throughout the world and became a major public health concern. Approximately 5-12% of COVID-19 patients require admission to the intensive-care unit (ICU), where they often require oxygen therapy and prolonged intubation. Post-intubation laryngotracheal stenosis (PILS) is a complication that occurs in 10-22% of non-COVID-19 patients after prolonged intubation, while the rate of COVID-19 related PILS remains unknown. Read More

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