913,063 results match your criteria total studies


Silica Xerogel Doped with Iron(III) as Sensor Material for Salicylhydroxamic Acid Determination in Urine.

Gels 2021 Sep 16;7(3). Epub 2021 Sep 16.

Analytical Chemistry Division, Chemistry Department, Lomonosov Moscow State University, 119234 Moscow, Russia.

Salicylhydroxamic acid (SHA) is used as antimicrobic medicine and its concentration has to be monitored in urine. For the first time, silica xerogels doped with iron(III) have been proposed as sensor materials for SHA determination in biological samples. Three xerogels with iron(III) content in the range of 0. Read More

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September 2021

The Mini-Cog, Clock Drawing Test, and Three-Item Recall Test: Rapid Cognitive Screening Tools with Comparable Performance in Detecting Mild NCD in Older Patients.

Geriatrics (Basel) 2021 Sep 16;6(3). Epub 2021 Sep 16.

Division of Geriatric Medicine, Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.

Background: Early mild neurocognitive disorder (mild NCD) detection can allow for appropriate planning and delay disease progression. There have been few studies examining validated mild NCD detection tools. One such tool that may be of use is the Mini-Cog, which consists of the clock drawing test (CDT) and three-item recall. Read More

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September 2021

The Impact of Wildfires on Mental Health: A Scoping Review.

Behav Sci (Basel) 2021 Sep 21;11(9). Epub 2021 Sep 21.

Department of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2B7, Canada.

One of the many consequences of climate change is an increase in the frequency, severity, and, thus, impact of wildfires across the globe. The destruction and loss of one's home, belongings, and surrounding community, and the threat to personal safety and the safety of loved ones can have significant consequences on survivors' mental health, which persist for years after. The objective of this scoping review was to identify primary studies examining the impact of wildfires on mental health and to summarize findings for PTSD, depression, anxiety, and substance use. Read More

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September 2021

Effectiveness of technology-assisted cardiac rehabilitation: A systematic review and meta-analysis.

Int J Nurs Stud 2021 Sep 5;124:104087. Epub 2021 Sep 5.

The Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR.

Objectives: The objectives of this review were to identify different technology-assisted interventions in cardiac rehabilitation, to explore and examine the effectiveness of technology-assisted cardiac rehabilitation.

Design: A systematic review and meta-analysis.

Methods: A systematic search was performed on six electronic databases: CINALH Complete, Cochrane Library, PubMed, MEDLINE via OvidSP, British Nursing Index and PsycINFO to identify randomised controlled trials from 2010 to 2020. Read More

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September 2021

Prognostic role of USP7 expression in cancer patients: A systematic review and meta-analysis.

Pathol Res Pract 2021 Sep 17;227:153621. Epub 2021 Sep 17.

College of Creative Studies, Niigata University, 8050 Ikarashi-nino-cho, Nishi-ku, Niigata 950-2181, Japan. Electronic address:

Background: Numerous studies have examined the prognostic value of ubiquitin-specific protease 7 (USP7) in cancer, but the results remain controversial. Differences in assessment assays (mRNA/protein) used could be a potential confounding factor. Thus, we extracted studies that measured the protein expression and performed a meta-analysis to assess the prognostic role of USP7 expression in cancer and to identify clinicopathological features associated with USP7 expression. Read More

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September 2021

Effect of diurnal temperature range on bioleaching of sulfide ore by an artificial microbial consortium.

Sci Total Environ 2021 Sep 9;806(Pt 1):150234. Epub 2021 Sep 9.

Guangzhou Key Laboratory Environmental Catalysis and Pollution Control, Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, School of Environmental Science and Engineering, Institute of Environmental Health and Pollution Control, Guangdong University of Technology, Guangzhou 510006, China.

Temperature is considered to be one of the main factors affecting bioleaching, but few studies have assessed the effects of diurnal temperature range (DTR) on the bioleaching process. This study investigates the effects of different bioleaching temperatures (30 and 40 °C) and DTR on the bioleaching of metal sulfide ores by microbial communities. The results showed that DTR had an obvious inhibitory effect on the bioleaching efficiency of the artificial microbial community, although this effect was mainly concentrated in the early and middle stages (0-18 days) of exposure, gradually decreasing until almost disappearing in the late stage (18-24 days). Read More

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September 2021

Transport and sources of nitrogen in stormwater runoff at the urban catchment scale.

Sci Total Environ 2021 Sep 11;806(Pt 1):150281. Epub 2021 Sep 11.

State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, 19 Xinjiekou Outer Street, Beijing 100875, PR China.

Revealing the transport and sources of nitrate in urban stormwater runoff can effectively manage nitrate pollution in urban areas. This study used the chemical properties of stormwater along with δN-NO and δO-NO isotopes to identify the transport and sources of nitrate within an urban catchment. The results showed that the NO-N concentration and total dissolved nitrogen (TDN) composition differed among roof runoff, road runoff, and drainage runoff. Read More

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September 2021

The role of nitrification inhibitors on the removal of antibiotics in livestock wastewater by aerobic biodegradation.

Sci Total Environ 2021 Sep 14;806(Pt 1):150309. Epub 2021 Sep 14.

National Engineering Laboratory for Industrial Wastewater Treatment, East China University of Science and Technology, Shanghai 200237, PR China; School of Resources and Environmental Engineering, East China University of Science and Technology, Shanghai 200237, PR China.

An optimized aerobic-based treatment method that effectively removes antibiotics and retains ammonia is urgently needed for the field-return-based management of livestock wastewater. Allylthiourea (ATU, used for BOD determination), and 2-chloro-6-trichloromethylpyridine (TCMP) and 3,4-dimethylpyrazole phosphate (DMPP) (commonly used as nitrogen fertilizer synergists) were separately added to sequencing batch reactors (SBRs), in order to investigate their effect on nitrification inhibition and pollutant removal for livestock wastewater treatment. The laboratory test shows that the daily addition of 43. Read More

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September 2021

Treatment of human intestinal cryptosporidiosis: A review of published clinical trials.

Int J Parasitol Drugs Drug Resist 2021 Sep 21;17:128-138. Epub 2021 Sep 21.

Department of Parasitology, Faculty of Medicine, University of Indonesia, Indonesia.

The global burden of diarrhea caused by Cryptosporidium parasite is underestimated. In immunocompromised hosts, chronic and severe presentation of intestinal cryptosporidiosis can result in long-term morbidity and high illness costs. The evidence of effective treatments for cryptosporidiosis has been lacking. Read More

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September 2021

Monochromatic X-rays: The future of breast imaging.

Eur J Radiol 2021 Sep 20;144:109961. Epub 2021 Sep 20.

Massachusetts General Hospital, Boston, MA, USA. Electronic address:

Purpose: To present details about the innovative and disruptive technology of monochromatic X-rays and its application to breast imaging.

Methods: To analyze results of studies done using a prototype system for breast imaging that generates monochromatic X-rays through fluorescence emission. To assess signal-to-noise ratio (SNR) as a measure of image quality at different doses in breast phantoms of different sizes and review the comparison of parameters with a standard mammography system. Read More

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September 2021

Alternative physical treatments for deep venous thrombosis prophylaxis in surgical patients: a systematic review.

Physiotherapy 2021 May 12;113:73-79. Epub 2021 May 12.

Imperial College NHS Trust, London, United Kingdom; Nuffield Department of Orthopaedic, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom. Electronic address:

Introduction: Venous thromboembolism (VTE) represents a major cause of morbidity and mortality. A variety of novel physical therapies have been proposed for patients in whom standard prophylaxis, including early mobilisation, is contraindicated. This article presents a systematic literature review of alternative physical treatments for VTE prophylaxis, focusing on surgical and trauma patients. Read More

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[Sentinel lymph node biopsy in the management of early-stage ovarian cancer: a systematic review of the literature.]

Gynecol Obstet Fertil Senol 2021 Sep 22. Epub 2021 Sep 22.

Service de Chirurgie Cancérologique Gynécologique et du Sein, APHP.Centre, Hôpital Européen Georges-Pompidou, 20 rue Leblanc, 75015, Paris, France. Electronic address:

The initial management of early-stage ovarian cancer consists of staging surgery including pelvic and para-aortic lymphadenectomy. The use of the sentinel lymph node (SLN) procedure in this setting may decrease the morbidity associated with this surgery. The objective of this review was to evaluate the feasibility of the SLN procedure in ovarian cancer diagnosed at an early stage by comparing the different techniques used and their accuracy. Read More

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September 2021

Catharanthus roseus (L.) G. Don: A review of its ethnobotany, phytochemistry, ethnopharmacology and toxicities.

J Ethnopharmacol 2021 Sep 22:114647. Epub 2021 Sep 22.

Department of Botany, Government Degree College Bahua Dehat, Fatehpur-212663 (affiliated to Professor Rajendra Singh (Rajju Bhaiya) University Prayagraj), Uttar, Pradesh, India.

Ethnopharmacological Relevance: Catharanthus roseus (L.) G. Don is a well known medicinal plant belonging to family Apocynaceae that have been traditionally used as medicine since ancient times. Read More

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September 2021

A simple method for obtaining human albumin and its use for in vitro interaction assays with indole-thiazole and indole-thiazolidinone derivatives.

Int J Biol Macromol 2021 Sep 22. Epub 2021 Sep 22.

Laboratório de Imunopatologia Keizo Asami (LIKA), Universidade Federal de Pernambuco, 50670-901, Brazil; Laboratório de Biologia Molecular, Universidade de Pernambuco (UPE), Multicampi Garanhuns, Garanhuns, PE 55290-000, Brazil. Electronic address:

This work aimed to develop a simple and low-cost method to obtain Human serum albumin (HSA) and its consequent application for in vitro drug interaction assays. The HSA was purified by classic principles of plasma precipitation and thermocoagulation, using a multiple-stage fractionation. The quality of the final product was assessed by electrophoresis, protein dosage by the Lowry method and the pharmacopeial thermal stability. Read More

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September 2021

DNA barcode identification and molecular detection of bluetongue virus in Culicoides biting midges (Diptera: Ceratopogonidae) from western Thailand.

Acta Trop 2021 Sep 22:106147. Epub 2021 Sep 22.

Department of Clinical Sciences and Public Health, Faculty of Veterinary Science, Mahidol University, Salaya, Phutthamonthon, Nakhon Pathom, 73170, Thailand. Electronic address:

Biting midges of the genus Culicoides Latreille are biological vectors of bluetongue virus (BTV), a member of family Reoviridae, genus Orbivirus. About 30 species of Culicoides have been identified as competent BTV vectors worldwide. Even though high seroprevalence of BTV has been reported among livestock ruminants from western Thailand, the Culicoides species which contribute to BTV transmission remain unclear. Read More

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September 2021

Factors Associated with Return to Work After Heart Transplantation: A Systematic Review of the Literature.

Am J Med Sci 2021 Sep 22. Epub 2021 Sep 22.

Cardiology Service, Department of Internal Medicine, Fundación Valle del Lili, Cali, Columbia.

Background: Heart transplantation represents one of the last treatment options for advanced heart failure. Little is known about the factors associated with return to work in patients after heart transplantation. The aim of this study is to identify those factors. Read More

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September 2021

Multi-omics network-based functional annotation of unknown Arabidopsis genes.

Plant J 2021 Sep 25. Epub 2021 Sep 25.

Ghent University, Department of Plant Biotechnology and Bioinformatics, Ghent, BE, Belgium.

Unraveling gene function is pivotal to understanding the signaling cascades that control plant development and stress responses. Since experimental profiling is costly and labor intensive, there is a clear need for high-confidence computational annotation. In contrast to detailed gene-specific functional information, transcriptomics data is widely available for both model and crop species. Read More

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September 2021

Generation of neutrophil extracellular traps in patients with acute liver failure is associated with poor outcome.

Hepatology 2021 Sep 25. Epub 2021 Sep 25.

Surgical Research Laboratory, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Background And Aims: Acute liver failure (ALF) is characterized by significant changes in the hemostatic system and by systemic inflammation. The formation of neutrophil extracellular traps (NETs), in which an activated neutrophil expels its DNA, histones and granular enzymes, such as myeloperoxidase (MPO), has been associated with immune-mediated and thrombotic diseases. We hypothesized that formation of NETs in patients with ALF contributes to progression of disease. Read More

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September 2021

Reliability of MRI radiomics features in MR-guided radiotherapy for prostate cancer: Repeatability, reproducibility, and within-subject agreement.

Med Phys 2021 Sep 25. Epub 2021 Sep 25.

Medical Physics and Research Department, Hong Kong Sanatorium & Hospital, Hong Kong, Hong Kong, SAR, China.

Purpose: The MR-guided radiotherapy (MRgRT) images on the integrated MRI and linear accelerator (MR-LINAC) might facilitate radiomics analysis for longitudinal treatment response assessment. However, the reliability of MRgRT radiomics features is largely unknown. This study aims to investigate MRgRT radiomics feature reliability acquired using a standardized 3D-T2W-TSE sequence in terms of repeatability, reproducibility, and within-subject feature agreement on a 1. Read More

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September 2021

Polymorphisms of the prion-related protein gene are strongly associated with cervids' susceptibility to chronic wasting disease.

Vet Rec 2021 Sep 25:e940. Epub 2021 Sep 25.

Korea Zoonosis Research Institute, Jeonbuk National University, Iksan, Republic of Korea.

Background: Chronic wasting disease (CWD) is a cervid prion disease that is caused by abnormal prion protein (PrP ). Recent studies have reported that prion family genes showed a strong association with the susceptibility of several types of prion diseases. To date, an association study of the prion-related protein gene (PRNT) has not been performed in any type of cervid prion disease. Read More

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September 2021

Quality of Life of Infants, Toddlers and Preschoolers with Seborrhoeic, Allergic Contact and Atopic Dermatitis Before and During COVID-19 Pandemic.

Dermatol Ther (Heidelb) 2021 Sep 25. Epub 2021 Sep 25.

Kiev City Clinical Dermatovenereologic Hospital, Kiev, Ukraine.

Introduction: Different aspects of quality of life (QoL) of infants and children with atopic dermatitis (AD) are well studied but there is a lack of studies on seborrhoeic dermatitis (SD) and allergic contact dermatitis (ACD). The aim of this study was to compare the impact of SD, ACD and AD on young children. Parts of questionnaires were filled in during the COVID-19 pandemic and therefore we decided to check if the pandemic affected dermatology-specific health-related quality of life (HRQoL) in our patients. Read More

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September 2021

Measuring and Manipulating Membrane Cholesterol for the Study of Hedgehog Signaling.

Methods Mol Biol 2022 ;2374:73-87

Department of Medicine and Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.

Cholesterol is an abundant lipid in mammalian plasma membranes that regulates the reception of the Hedgehog (Hh) signal in target cells. In vertebrates, cell-surface organelles called primary cilia function as compartments for the propagation of Hh signals. Recent structural, biochemical, and cell-biological studies have led to the model that Patched-1 (PTCH1), the receptor for Hh ligands, uses its transporter-like activity to lower cholesterol accessibility in the membrane surrounding primary cilia. Read More

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January 2022

Effects of supplementation on production and age anticipation at first mating of ewe lambs in tropical pastures.

Trop Anim Health Prod 2021 Sep 25;53(5):481. Epub 2021 Sep 25.

College of Veterinary Medicine and Animal Science of the Federal University of Mato Grosso Do Sul (UFMS), Av. Senador Filinto Muller, 2443. Vila Ipiranga, Campo Grande, MS, CEP 79070-900, Brazil.

Studies on the rearing of ewe lambs in the Cerrado are scarce, so the objective was to evaluate the effects of protein-energy supplementation with 1.6 and 2.4% BW on the productive and reproductive performance of ewe lambs raised on pastures of Brachiaria brizantha cv. Read More

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September 2021

A prospective study of the use of central venous catheters in patients newly diagnosed with acute myeloid leukemia treated with induction chemotherapy.

Support Care Cancer 2021 Sep 25. Epub 2021 Sep 25.

Division of Hematology-Oncology, University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, 5150 Center Ave, Suite 564, Pittsburgh, PA, 15232, USA.

Purpose: Central venous catheters (CVCs) are widely used in acute myeloid leukemia (AML) patients. Complications associated with CVCs are frequently encountered and contribute to morbidity and mortality. Prospective studies investigating and comparing complications of different types of CVCs in AML patients and their effects on the quality of life are limited. Read More

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September 2021

A systematic review and meta-analysis of robotic-assisted transabdominal total mesorectal excision and transanal total mesorectal excision: which approach offers optimal short-term outcomes for mid-to-low rectal adenocarcinoma?

Tech Coloproctol 2021 Sep 25. Epub 2021 Sep 25.

Kings College Hospitals, Princess Royal University Hospital, Farnborough Common, London, BR6 8ND, Kent, UK.

Background: Resection of low rectal adenocarcinoma can be challenging in the narrow pelvis of male patients. Transanal total mesorectal excision (TaTME) appears to offer technical advantages for distal rectal tumours, and robotic-assisted transabdominal TME (rTME) was introduced in effort to improve operative precision and ergonomics. However, no study has comprehensively compared these approaches. Read More

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September 2021

Predictive value of gadoxetic acid-enhanced MRI for posthepatectomy liver failure: a systematic review.

Eur Radiol 2021 Sep 25. Epub 2021 Sep 25.

Division of Medical Imaging and Technology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.

Objectives: Effective and non-invasive biomarkers to predict and avoid posthepatectomy liver failure (PHLF) are urgently needed. This systematic review aims to evaluate the efficacy of gadoxetic acid-enhanced MRI-derived parameters as an imaging biomarker in preoperative prediction of PHLF.

Methods: A systematic literature search was performed in the databases of PubMed/Medline, Web of Science, Embase, and Cochrane Library up to 11 December 2020. Read More

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September 2021

Lipidomics reveals perturbations in the liver lipid profile of iron overloaded mice.

Metallomics 2021 Sep 25. Epub 2021 Sep 25.

College of Animal Sciences, Zhejiang University, Key Laboratory of Animal Feed and Nutrition of Zhejiang Province, Hangzhou, 310058, China.

Iron overload is an important contributor to disease. The liver, the major site of iron storage in the body, is a key organ impacted by iron overload. While several studies have reported perturbations in liver lipids in iron overload, it is not clear, on a global scale, how individual liver lipid ions are altered. Read More

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September 2021

Outcomes of skin cancers in pediatric solid organ transplant patients: A systematic review.

Pediatr Transplant 2021 Sep 25:e14146. Epub 2021 Sep 25.

Division of Dermatology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

Background: The most frequently reported malignancies after solid organ transplant are cutaneous, but data on the risk in pediatric populations varies across studies.

Objectives: To perform a systematic review including reported features and outcomes of skin cancers in pediatric solid organ transplant recipients.

Methods: EMBASE and MEDLINE were systematically searched (Prospero CRD42020201659). Read More

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September 2021

Intra-abdominal vascularized lymph node transfer for treatment of lymphedema: A systematic literature review and meta-analysis.

Microsurgery 2021 Sep 25. Epub 2021 Sep 25.

Department of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

Background: As a promising treatment for lymphedema, vascularized lymph node transfer (VLNT) is associated with a risk of iatrogenic lymphedema. Intra-abdominal vascularized lymph node flap has been increasingly applied to minimize complication.

Methods: PubMed, EMBASE, Web of Sciences, and Cochrane databases were searched systematically. Read More

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September 2021

Detethering the Superficial Temporal Artery: Application to Tension Free STA-MCA Bypasses.

Clin Anat 2021 Sep 25. Epub 2021 Sep 25.

Department of Neurosurgery, Ochsner Health System, New Orleans, Louisiana, USA.

Background: Extracranial-intracranial bypass has been shown to be effective in the surgical treatment of moyamoya disease, complex aneurysms, and tumors that involve proximal vasculature in carefully selected patients. Branches of the superficial temporal artery (STA) are used commonly for the bypass surgery; however, an appropriate length of the donor vessel must be harvested to avoid failure secondary to anastomotic tension. The goal of this cadaveric study was to investigate quantitatively operative techniques that can increase the STA length available to facilitate tension-free STA-middle cerebral artery (MCA) bypass. Read More

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September 2021