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Pulmonary Open, Robotic and Thoracoscopic Lobectomy (PORTaL) Study: An Analysis of 5,721 Cases.

Ann Surg 2021 Sep 16. Epub 2021 Sep 16.

Division of Thoracic Surgery, and Interventional Pulmonology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA Division of Thoracic Surgery, Duke University, Durham, NC Division of Thoracic Surgery, Swedish Cancer Institute, Seattle, WA Division of Thoracic Surgery, Temple University Health System, Philadelphia, PA Division of Thoracic Surgery, NYU Langone, New York, NY General Thoracic Surgery, Baptist Health Medical Group, South Miami, FL Division of Thoracic Surgery, Albany Medical Center, Albany, NY Rod Taylor Thoracic Care Center, Orlando Health UF Health Cancer Center, Orlando FL Division of Thoracic Surgery, Baylor Scott & White The Heart Hospital - Plano, Plano, TX Department of Cardiothoracic Surgery, Northwell Health, New York, NY Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO Division of Thoracic Surgery, NYU Winthrop, Mineola, NY Division of Thoracic Surgery, University of Michigan Medical Center, Ann Arbor, MI Division of Thoracic Surgery, Penn State Cancer Institute, Hershey, PA Department of Thoracic and Cardiovascular Surgery, The University of Texas M.D. Anderson Cancer Main Line Health Care Thoracic Surgery, Main Line Health, Wynewood, PA Department of Cardiothoracic Surgery, Division of Thoracic Surgery, UPMC, Pittsburgh, PA Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA Division of Thoracic Surgery, Aurora Health Care, Grafton, MI Division of General Thoracic Surgery, Mayo Clinic, Rochester, MN.

Objective: The aim of this study was to analyze outcomes of open lobectomy (OL), video-assisted thoracoscopic lobectomy (VATS) and robotic-assisted lobectomy (RL).

Summary Background Data: Robotic-assisted lobectomy has seen increasing adoption for treatment of early-stage lung cancer. Comparative data regarding these approaches is largely from single-institution case series or administrative datasets. Read More

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September 2021

Placental apoptotic markers are associated with placental morphometry.

Placenta 2021 Aug 19;115:1-11. Epub 2021 Aug 19.

Department of Mother and Child Health, Interactive Research School for Health Affairs (IRSHA), Bharati Vidyapeeth (Deemed to Be University), Pune-Satara Road, Pune, 411043, India. Electronic address:

Introduction: Preeclampsia is a hypertensive disorder affecting both mother and the fetus and is a major cause of maternal and neonatal morbidity and mortality. Abnormal placentation is a common feature in preeclampsia that contributes to placental dysfunction. It is likely that increased homocysteine and oxidative stress influence apoptosis in preeclampsia. Read More

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A systematic comparison of neurotoxicity of bisphenol A and its derivatives in zebrafish.

Sci Total Environ 2021 Sep 8;805:150210. Epub 2021 Sep 8.

Nanjing Institute of Environmental Sciences, Ministry of Ecology and Environment, Nanjing 210042, China. Electronic address:

As more and more countries have prohibited the manufacture and sale of plastic products with bisphenol A (BPA), a number of bisphenol analogues (BPs), including BPS, BPF and BPAF, have gradually been used as its primary substitutes. Ideally, substitutes used to replace chemicals with environmental risks should be inert, so it makes sense that the risk of the similar chemical substitutes (BPS, BPF, and BPAF) should be assessed before they used. Therefore, in the present study, the neurotoxicity of four BPs at environmentally relevant concentration (200 μg/L) were systematically compared using zebrafish as a model. Read More

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September 2021

Sustained swimming exercise training decreases the individual variation in the metabolic phenotype of gilthead sea bream (Sparus aurata).

Comp Biochem Physiol A Mol Integr Physiol 2021 Sep 14:111077. Epub 2021 Sep 14.

CIIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Portugal. Electronic address:

Cultured fish can be induced to swim, although the suitability and benefits remain to be tested. Sustained swimming exercise (SSE) training and detraining (DET) were applied in juvenile gilthead sea bream (Sparus aurata) and the metabolic rates were investigated. Fish with a total body mass of 80. Read More

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September 2021

Trends in Heart Failure Hospitalizations in the US from 2008 to 2018: Trends in Heart Failure Hospitalizations.

J Card Fail 2021 Sep 14. Epub 2021 Sep 14.

Division of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Center for Outcomes Research and Evaluation, New Haven, CT. Electronic address:

Background: Heart failure (HF) is a major driver of healthcare costs in the United States and is increasing in prevalence. There is a paucity of contemporary data examining trends among HF hospitalizations, specifically comparing HF with reduced and preserved ejection fraction (HFrEF and HFpEF, respectively).

Methods And Results: Using the National Inpatient Sample (NIS), we identified 11,692,995 hospitalizations for HF. Read More

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September 2021

Vestibular Perceptual Thresholds in Older Adults With and Without Age-related Hearing Loss.

Ear Hear 2021 Sep 15. Epub 2021 Sep 15.

KITE-Toronto Rehabilitation Institute, University Health Network, Toronto, ON, Canada Department of Psychology, University of Toronto, Toronto, ON, Canada Department of Psychology and Centre for Vision Research, York University, Toronto, ON, Canada Department of Otolaryngology-Head & Neck Surgery Hospital for Sick Children, Toronto, ON, Canada Department of Otolaryngology-Head & Neck Surgery, University of Toronto, Toronto, ON, Canada Archie's Cochlear Implant Laboratory, Hospital for Sick Children, Toronto, ON, Canada University of Toronto Institute for Aerospace Studies, Toronto, ON, Canada.

Objectives: Older adults with age-related hearing loss (ARHL) are at greater risk of falling and have greater mobility problems than older adults with normal hearing (NH). The underlying cause of these associations remains unclear. One possible reason is that age-related declines in the vestibular system could parallel those observed in the auditory system within the same individuals. Read More

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September 2021

Descriptive Epidemiology and Outcomes of Nonventilated Hospital-Acquired, Ventilated Hospital-Acquired, and Ventilator-Associated Bacterial Pneumonia in the United States, 2012-2019.

Crit Care Med 2021 Sep 16. Epub 2021 Sep 16.

Division of Health Services Research, EviMed Research Group, LLC, Goshen, MA. OptiStatim, LLC, Longmeadow, MA. Merck, Kenilworth, NJ. Department of Pulmonary and Critical Care Medicine, Washington Hospital Center, Washington, DC.

Objectives: Multiple randomized controlled trials exploring the outcomes of patients with ventilator-associated bacterial pneumonia and hospital-acquired bacterial pneumonia have noted that hospital-acquired bacterial pneumonia patients who require subsequent ventilated hospital-acquired bacterial pneumonia suffered higher mortality than either those who did not (nonventilated hospital-acquired bacterial pneumonia) or had ventilator-associated bacterial pneumonia. We examined the epidemiology and outcomes of all three conditions in a large U.S. Read More

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September 2021

Improved Whole-Genome Sequence of Fusarium meridionale, the Fungal Pathogen Causing Fusarium Head Blight in Rice.

Mol Plant Microbe Interact 2021 Sep 17. Epub 2021 Sep 17.

Institute of Food Safey and Nutrition, Jiangsu Academy of Agricultural Sciences, Nanjing, China;

Members of the Fusarium graminearum species complex (FGSC) cause extensive yield losses in cereal production worldwide and food safety concerns due to the accumulation of Fusarium toxins in infected grains. Among these pathogens, F. meridionale is responsible for Fusarium head blight of wheat and rice, ear and stalk rot of maize, and pod blight of soybean. Read More

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September 2021

Choline acts during preimplantation development of the bovine embryo to program postnatal growth and alter muscle DNA methylation.

FASEB J 2021 Oct;35(10):e21926

Department of Animal Sciences and D.H. Barron Reproductive and Perinatal Biology Research Program, and Genetics Institute, University of Florida, Gainesville, Florida, USA.

The preimplantation period of embryonic development can be a key window for programming of postnatal development because extensive epigenetic remodeling occurs during this time. It was hypothesized that modification of one-carbon metabolism of the bovine embryo by addition of the methyl-donor choline to culture medium would change postnatal phenotype through epigenetic modification. Embryos produced in vitro were cultured with 1. Read More

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October 2021

Introgression and QTL mapping conferring resistance for Alternaria brassicae in the backcross progeny of Sinapis alba + Brassica juncea somatic hybrids.

Plant Cell Rep 2021 Sep 17. Epub 2021 Sep 17.

Genetics Division, ICAR-Indian Agriculture Research Institute, Pusa Campus, New Delhi, 110012, India.

Key Message: A total of three QTLs, responsible for A. brassicae resistance were introgressed into S. alba - B. Read More

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September 2021

[Influence of complications and comorbidities on length of hospital stay and costs for surgical treatment of proximal humeral fractures].

Chirurg 2021 Sep 17. Epub 2021 Sep 17.

Klinik für Unfall‑, Hand- und Wiederherstellungschirurgie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, Gebäude W1, 48149, Münster, Deutschland.

After a proximal humeral fracture in older patients, locked plate fixation and reverse total shoulder arthroplasty are two competing surgical procedures. Even if recent clinical studies indicate a functional superiority of reverse shoulder arthroplasty over locked plate fixation, health-economic comparative data are lacking in the literature. Health claims data of 55,070 patients aged 65 years or older who were treated with reverse total shoulder arthroplasty or locked plate fixation after proximal humeral fractures, were analyzed regarding length of hospital stay and costs. Read More

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September 2021

Reconstruction of C1 lateral mass with an expandable cage in addition to vertebral artery preservation: presenting two cases.

Br J Neurosurg 2021 Sep 17:1-6. Epub 2021 Sep 17.

Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.

Purpose: C1 lateral mass reconstruction is recommended, in cases of instability caused by tumor involvement or extensive C1 lateral mass resection. However, because of the anatomical complexity of the area and, most importantly, the proximity to vertebral arteries, few cases of reconstruction have been reported to date. The purpose of this report is to present technical details of C1 lateral mass reconstruction in conjunction with vertebral artery preservation from a posterior approach. Read More

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September 2021

Leaf trait variation during ontogeny in the endangered Brazilian rosewood tree.

Plant Biol (Stuttg) 2021 Sep 16. Epub 2021 Sep 16.

Departamento de Botânica, Universidade Federal de Minas Gerais, ICB-UFMG, Avenida Antonio Carlos, 6627, Belo Horizonte, Brasil, 31270-901, Brazil.

Knowledge of plant responses to environmental heterogeneity during ontogeny is important to elucidate the changes that occur to promote resource capture in tropical forests. We tested the hypothesis that expression changes in leaf metamer traits of Brazilian rosewood (Dalbergia nigra), from seedlings to emergent canopy trees, occur as new microclimate environments are achieved. We also tested the hypothesis that increased light heterogeneity in the understorey leads to higher plasticity in leaf traits of seedlings and saplings than in sun-exposed metamers of emergent trees subject to stressful conditions. Read More

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September 2021

Flame burns.

Dermatol Ther 2021 Sep 16:e15133. Epub 2021 Sep 16.

Gazi Yasargil Training and Research Hospital Department of General Surgery, Diyarbakır, Turkey.

Introduction: Flame burns lead to significant long-term morbidity and functional consequences. This study analysed the mortality-related factors in patients with flame burns to compare with the existing literature.

Methods: This retrospective descriptive study was carried out at the General Surgery Clinic, Gazi YaŞargil Training and Research Hospital, Turkey, to include 131 patients admitted and treated with emergency surgery for flame burns between January 2016 and December 2019. Read More

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September 2021

The complete chloroplast genome sequence of the endemic and rare orchid (Orchidaceae) in China.

Mitochondrial DNA B Resour 2021 13;6(10):2931-2932. Epub 2021 Sep 13.

College of Biological Sciences and Technology, Beijing Laboratory of Urban and Rural Ecological Environment, Beijing Key Laboratory of Ornamental Plants Germplasm Innovation and Molecular Breeding, National Engineering Laboratory for Tree Breeding, Beijing Forestry University, Beijing, China.

(Orchidaceae) is a rare orchid unique to China of great horticultural value. The complete chloroplast (cp) genome of this species is 143,522 bp in length and the total GC content is 36.8%. Read More

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September 2021

Complete mitochondrial genome sequence and phylogenetic analysis of (Stylommatophora: Arionidae).

Mitochondrial DNA B Resour 2021 13;6(10):2928-2930. Epub 2021 Sep 13.

College of Life Science, Qufu Normal University, Qufu, Shandong, PR China.

are a group of mollusks, almost all of which live in a dark and humid environment during their life cycle. In this study, the complete mitogenome of was sequenced using next generation sequencing, analyzed and compared with other Stylommatophorans. The total length of the mitochondrial genome is 14,314 bp and consists of 13 protein-coding genes, 22 tRNA genes, 2 rRNA genes, and 1 control region. Read More

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September 2021

The complete chloroplast genome and phylogenetic analysis of (Rutaceae).

Mitochondrial DNA B Resour 2021 13;6(10):2926-2927. Epub 2021 Sep 13.

School of Information Science and Technology, Nanjing Forestry University, Nanjing, China.

Citrus, which is widely cultivated in tropical and subtropical climates, is one of the most important crops in the world. Here, we assembled and annotated the complete chloroplast genome of () using Illumina sequencing data. This chloroplast genome exhibited a typical quadripartite structure of 154,042 bp in length, and the overall GC content was 38. Read More

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September 2021

Complete chloroplast genome of (Isoetaceae), the Endangered quillwort in China.

Mitochondrial DNA B Resour 2021 13;6(10):2908-2909. Epub 2021 Sep 13.

Key Laboratory of National Forestry and Grassland Administration for Orchid Conservation and Utilization, The National Orchid Conservation & Research Center of Shenzhen, Shenzhen, Guangdong, China.

Hand.-Mazz. is an Endangered quillwort living in plateau wetlands in China. Read More

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September 2021

Complete chloroplast genome of a rare and endangered plant species : genomic features and phylogenetic relationship within Orchidaceae.

Mitochondrial DNA B Resour 2021 9;6(10):2872-2879. Epub 2021 Sep 9.

College of Life Sciences, Taizhou University, Taizhou, PR China.

is a rare and endangered plant species with extremely small populations. The complete chloroplast (cp) genome of was assembled, its structural organization was described and comparative genomic analyses was carried out. The cp genome of is 143,547 bp in length, with a GC content of 37. Read More

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September 2021

Factors associated with high prevalence of PfCRT K76T mutation in isolates in a rural and urban community of Ogun State, Nigeria.

Malariaworld J 2017 1;8:13. Epub 2017 Aug 1.

Biochemistry Research Unit, Akanu Ibiam Federal Polytechnic, Unwana, Ebonyi State, Nigeria.

Background: Antimalarial drug-resistant strains have been a major obstacle to the global efforts of controlling and eliminating malaria. The hope of reintroducing chloroquine for the treatment of uncomplicated malaria follows recent reports on decreases in the prevalence of chloroquine-resistant in several countries and recently, its total disappearance in Malawi and Zambia. In Nigeria, the discontinued use of chloroquine for malaria treatment was officially announced in 2005. Read More

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Comparative study on short-term efficacy of single incision plus one (SI+1) port and multiportal 3D laparoscopic minimally invasive esophagectomy.

J Gastrointest Oncol 2021 Aug;12(4):1277-1284

Department of Thoracic Surgery, Shanghai Changzheng Hospital, Navy Military Medical University, Shanghai, China.

Background: To evaluate the safety and efficacy of single incision plus one (SI+1) port three-dimensional (3D) laparoscopic minimally invasive esophagectomy (MIE).

Methods: Clinical data of patients who underwent 3D thoracic laparoscopic MIE in our department from September 2020 to March 2021 were analyzed retrospectively. According to the different methods of laparoscopic surgery, the patients were divided into 2 groups: SI+1 port 3D laparoscopy group and multiportal 3D laparoscopy group. Read More

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Feeding containing the aerial part of promotes the growth and nutritive value of rabbit fish .

Food Sci Nutr 2021 Sep 28;9(9):4827-4838. Epub 2021 Jul 28.

Shenzhen Key Laboratory of Edible and Medicinal Bioresources HKUST Shenzhen Research Institute Shenzhen China.

The root of (Scutellaria Radix) has been used as herbal medicine for years, while its stem and leaf (aerial part) are considered as waste. The water extract from the aerial part of (named as SBA) being included in the feeding of (grey rabbit fish) has been shown to replace antibiotics in aquaculture with excellent outcome. To strengthen the usage of SBA in fish feeding, the total fish output and its nutritive value were determined here. Read More

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September 2021

Mouse model of experimental pulmonary hypertension: Lung angiogram and right heart catheterization.

Pulm Circ 2021 Oct-Dec;11(4):20458940211041512. Epub 2021 Sep 8.

Section of Physiology, University of California, San Diego, La Jolla, CA, USA.

Pulmonary arterial hypertension is a progressive and fatal disease and rodents with experimental pulmonary hypertension (PH) are often used to study pathogenic mechanisms, identify therapeutic targets, and develop novel drugs for treatment. Here we describe a hands-on set of experimental approaches including ex vivo lung angiography and histology and in vivo right heart catheterization (RHC) to phenotypically characterize pulmonary hemodynamics and lung vascular structure in normal mice and mice with experimental PH. We utilized Microfil polymer as contrast in our ex vivo lung angiogram to quantitatively examine pulmonary vascular remodeling in mice with experimental PH, and lung histology to estimate pulmonary artery wall thickness. Read More

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September 2021

Transcriptome and Metabolome Analyses of the Flowers and Leaves of .

Front Genet 2021 31;12:716163. Epub 2021 Aug 31.

Beijing Key Laboratory of Agricultural Genetic Resources and Biotechnology, Beijing Agro-Biotechnology Research Center, Beijing Academy of Agriculture and Forestry Sciences, Beijing Engineering Research Center of Functional Floriculture, Beijing, China.

is an important wild species in the family Asteraceae. However, because of a lack of genetic information, there has been relatively little research conducted on the molecular mechanisms in . There is no report describing the transcriptome and metabolome of flowers and leaves at different developmental stages. Read More

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The Response of Grain Yield and Root Morphological and Physiological Traits to Nitrogen Levels in Paddy Rice.

Front Plant Sci 2021 31;12:713814. Epub 2021 Aug 31.

Key Laboratory of Germplasm Enhancement, Physiology and Ecology of Food Crops in Cold Region, Ministry of Education, Northeast Agricultural University, Harbin, China.

Rice ( L.) is an important crop in China. Although it is known that its yield is restricted by nitrogen (N) supply, the response of the root system to N supply specifically has not been systematically explored. Read More

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The Relationship Between Body Mass Index and In-Hospital Mortality in the Contemporary Era of an Acute Myocardial Infarction Management.

Vasc Health Risk Manag 2021 10;17:551-559. Epub 2021 Sep 10.

Department of Cardiology, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Background: The association between body mass index (BMI) and clinical outcomes following an acute myocardial infarction (AMI) remains controversial. Our objective was to investigate the relationship between BMI and AMI presentation, in-hospital clinical course and mortality in the contemporary era of AMI management.

Methods: Patients, hospitalized for an AMI between October 2015 and December 2016, were identified in the National Inpatient Sample (NIS) database. Read More

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September 2021

Blood Count Parameters can be Useful in Predicting Vascular Events in Microvascular Surgery: Results of a Preliminary Study.

Niger J Clin Pract 2021 Sep;24(9):1343-1349

Department of Otolaryngology, Ege University Medical School and Hospital, Izmir, Turkey.

Background: Vascular events are a major cause of flap failure and identifying patients who are at risk is of paramount importance. In the past, many studies have been conducted to investigate the effect of blood count parameters for ischemic events such as peripheral vascular diseases.

Aims: This study aimed to evaluate whether blood count parameters can have predictive value for vascular events in microvascular flap surgery. Read More

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September 2021

Hospital outcomes in pediatric patients with Prader-Willi syndrome (PWS) undergoing orthopedic surgery: A 12-year analysis of national trends in surgical management and inpatient hospital outcomes.

J Orthop Sci 2021 Sep 13. Epub 2021 Sep 13.

Department of Orthopedics, Phoenix Children Hospital, Phoenix, 1919 E Thomas Rd, Phoenix, AZ, 85016, USA.

Background: The incidence of orthopedic disorders amongst patients with Prader-Willi Syndrome (PWS) is high when compared to the general pediatric population. The purpose of this retrospective study was to define the most commonly performed orthopedic procedures in pediatric patients with PWS and to characterize the peri-operative outcomes of these patients.

Methods: The Kids Inpatient Database (KID) was queried to collect data and identify all pediatric patients with PWS who underwent orthopedic procedures from 2001 to 2012. Read More

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September 2021

Alpha-blockade during congenital heart surgery admissions: analysis from national database.

Cardiol Young 2021 Sep 17:1-7. Epub 2021 Sep 17.

Cardiology, Advocate Children's Hospital, Chicago, IL, USA.

Introduction: The effects of alpha-blockade on haemodynamics during and following congenital heart surgery are well documented, but data on patient outcomes, mortality, and hospital charges are limited. The purpose of this study was to characterise the use of alpha-blockade during congenital heart surgery admissions and to determine its association with common clinical outcomes.

Materials And Methods: A cross-sectional study was conducted using the Pediatric Health Information System database. Read More

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September 2021

Trends in the incidence and outcome of sepsis using data from a Japanese nationwide medical claims database-the Japan Sepsis Alliance (JaSA) study group.

Crit Care 2021 Sep 16;25(1):338. Epub 2021 Sep 16.

Department of Health Policy and Informatics, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, Tokyo, Japan.

Background: Trends in the incidence and outcomes of sepsis using a Japanese nationwide database were investigated.

Methods: This was a retrospective cohort study. Adult patients, who had both presumed serious infections and acute organ dysfunction, between 2010 and 2017 were extracted using a combined method of administrative and electronic health record data from the Japanese nationwide medical claim database, which covered 71. Read More

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September 2021