340,657 results match your criteria tolerance


Assessment of the Transfer of Trace Metals to Spontaneous Plants on Abandoned Pyrrhotite Mine: Potential Application for Phytostabilization of Phosphate Wastes.

Plants (Basel) 2022 Jan 11;11(2). Epub 2022 Jan 11.

Laboratory of Plant Physiology and Biotechnology, Laboratoire Mixte International-LMI AMIR, Research Center on Plant and Microbial Biotechnology, Biodiversity and Environment, Faculty of Sciences, Mohammed V University in Rabat, Rabat 10001, Morocco.

The abandoned Kettara pyrrhotite mine (Marrakech region, Morocco) is a real source of acid mine drainage (AMD) and heavy metal pollution from previous mining operations-which has spread, particularly because of wind erosion. A store-and-release cover system made of phosphate wastes was built on the site for preventing AMD. To ensure the integrity of this cover and its durability, it is desirable to revegetate it (phytostabilization) with plants adapted to the edaphoclimatic conditions of the region. Read More

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January 2022

Diurnal Change of the Photosynthetic Light-Response Curve of Buckbean (), an Emergent Aquatic Plant.

Plants (Basel) 2022 Jan 10;11(2). Epub 2022 Jan 10.

Department of Agriculture, Forestry and Bioresources, Seoul National University, Seoul 08826, Korea.

Understanding plant physiological responses to high temperature is an important concern pertaining to climate change. However, compared with terrestrial plants, information about aquatic plants remains limited. Since the degree of midday depression of photosynthesis under high temperature depends on soil water conditions, it is expected that emergent aquatic plants, for which soil water conditions are always saturated, will show different patterns compared with terrestrial plants. Read More

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January 2022

Aluminum Stress Induces Irreversible Proteomic Changes in the Roots of the Sensitive but Not the Tolerant Genotype of Triticale Seedlings.

Plants (Basel) 2022 Jan 8;11(2). Epub 2022 Jan 8.

Department of Biochemistry and Biotechnology, Plant Breeding and Acclimatization Institute-National Research Institute in Radzików, 05-870 Blonie, Poland.

Triticale is a wheat-rye hybrid with a higher abiotic stress tolerance than wheat and is better adapted for cultivation in light-type soils, where aluminum ions are present as Al-complexes that are harmful to plants. The roots are the first plant organs to contact these ions and the inhibition of root growth is one of the first plant reactions. The proteomes of the root apices in Al-tolerant and -sensitive plants were investigated to compare their regeneration effects following stress. Read More

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January 2022

Down-Regulation of Cytokinin Receptor Gene Improves Plant Tolerance to Drought, Heat, and Combined Stresses in Tomato.

Plants (Basel) 2022 Jan 7;11(2). Epub 2022 Jan 7.

State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Horticulture, Nanjing Agricultural University, Nanjing 210095, China.

Environmental stresses negatively affect the growth and development of plants. Several previous studies have elucidated the response mechanisms of plants to drought and heat applied separately; however, these two abiotic stresses often coincide in environmental conditions. The global climate change pattern has projected that combined drought and heat stresses will tend to increase in the near future. Read More

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January 2022

Characterization and Evaluation of spp. (Metsch.) Sorokin Isolates for Their Temperature Tolerance.

J Fungi (Basel) 2022 Jan 10;8(1). Epub 2022 Jan 10.

Division of Livestock and Human Diseases Vector Control, Tropical Pesticides Research Institute, P.O. Box 3024, Arusha 23xxx, Tanzania.

A field survey was done in teak ( F.) forests in South India to explore the entomopathogenic effect of (Ascomycota: Sordariomycetes) against teak defoliator, (Lepidoptera: Hyblaeidae). About 300 soils and infected insect samples were collected during the survey and thirty-six fungal isolates were isolated from soil and insect samples and characterized. Read More

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January 2022

A Simple and Low-Cost Strategy to Improve Conidial Yield and Stress Resistance of through Optimizing Illumination Conditions.

J Fungi (Basel) 2022 Jan 5;8(1). Epub 2022 Jan 5.

Laboratory of Bio-Interactions and Crop Health, Jiangsu Provincial Key Lab for Organic Solid Waste Utilization, National Engineering Research Center for Organic-Based Fertilizers, Jiangsu Collaborative Innovation Center for Solid Organic Waste Resource Utilization, Nanjing Agricultural University, Nanjing 210095, China.

Light is perceived by photoreceptors in fungi and further integrated into the stress-activated MAPK HOG pathway, and thereby potentially activates the expression of genes for stress responses. This indicates that the precise control of light conditions can likely improve the conidial yield and stress resistance to guarantee the low cost and long shelf life of -based biocontrol agents and biofertilizers. In this study, effects of wavelengths and intensities of light on conidial yield and stress tolerance to osmotic, oxidative and pH stresses in were investigated. Read More

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January 2022

Purine Auxotrophic Starvation Evokes Phenotype Similar to Stationary Phase Cells in Budding Yeast.

J Fungi (Basel) 2021 Dec 29;8(1). Epub 2021 Dec 29.

Institute of Microbiology and Biotechnology, University of Latvia, Jelgavas 1, LV-1004 Riga, Latvia.

Purine auxotrophy is an abundant trait among eukaryotic parasites and a typical marker for many budding yeast strains. Supplementation with an additional purine source (such as adenine) is necessary to cultivate these strains. If not supplied in adequate amounts, purine starvation sets in. Read More

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December 2021

Application of Microalgal Stress Responses in Industrial Microalgal Production Systems.

Mar Drugs 2021 Dec 26;20(1). Epub 2021 Dec 26.

College of Food Science and Engineering, Ocean University of China, Qingdao 266003, China.

Adaptive laboratory evolution (ALE) has been widely utilized as a tool for developing new biological and phenotypic functions to explore strain improvement for microalgal production. Specifically, ALE has been utilized to evolve strains to better adapt to defined conditions. It has become a new solution to improve the performance of strains in microalgae biotechnology. Read More

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December 2021

Semi-Synthesis, Cytotoxic Evaluation, and Structure-Activity Relationships of Brefeldin A Derivatives with Antileukemia Activity.

Mar Drugs 2021 Dec 24;20(1). Epub 2021 Dec 24.

Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.

Brefeldin A (), a potent cytotoxic natural macrolactone, was produced by the marine fungus sp. (HS-N-29) from the medicinal mangrove . Series of its ester derivatives - were designed and semi-synthesized, and their structures were characterized by spectroscopic methods. Read More

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December 2021

One-Pot Ionic Liquid-Mediated Bioprocess for Pretreatment and Enzymatic Hydrolysis of Rice Straw with Ionic Liquid-Tolerance Bacterial Cellulase.

Bioengineering (Basel) 2022 Jan 6;9(1). Epub 2022 Jan 6.

Department of Chemical and Environmental Engineering, Faculty of Engineering, University of Nottingham Malaysia, Semenyih 43500, Selangor, Malaysia.

Ionic liquid (IL) pretreatment of lignocellulose is an efficient method for the enhancement of enzymatic saccharification. However, the remaining residues of ILs deactivate cellulase, therefore making intensive biomass washing after pretreatment necessary. This study aimed to develop the one-pot process combining IL pretreatment and enzymatic saccharification by using low-toxic choline acetate ([Ch][OAc]) and IL-tolerant bacterial cellulases. Read More

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January 2022

Retrospective Evaluation and Framework Development of Bone Anisotropic Material Behavior Compared with Elastic, Elastic-Plastic, and Hyper-Elastic Properties.

Bioengineering (Basel) 2021 Dec 29;9(1). Epub 2021 Dec 29.

Department of Biomedical, Industrial, and Human Factors Engineering, Wright State University, Dayton, OH 45435, USA.

The main motivation for studying damage in bone tissue is to better understand how damage develops in the bone tissue and how it progresses. Such knowledge may help in the surgical aspects of joint replacement, fracture fixation or establishing the fracture tolerance of bones to prevent injury. Currently, there are no standards that create a realistic bone model with anisotropic material properties, although several protocols have been suggested. Read More

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December 2021

Prospective Randomized Phase II Study of Stereotactic Body Radiotherapy (SBRT) vs. Conventional Fractionated Radiotherapy (CFRT) for Chinese Patients with Early-Stage Localized Prostate Cancer.

Curr Oncol 2021 Dec 22;29(1):27-37. Epub 2021 Dec 22.

Department of Clinical Oncology, State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute and Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.

Background: Stereotactic body radiotherapy (SBRT) has potential radiobiologic and economic advantages over conventional fractionated radiotherapy (CFRT) in localized prostate cancer (PC). This study aimed to compare the effects of these two distinct fractionations on patient-reported quality of life (PRQOL) and tolerability.

Methods: In this prospective phase II study, patients with low- and intermediate-risk localized PC were randomly assigned in a 1:1 ratio to the SBRT (36. Read More

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December 2021

Impact of Impaired Glucose Metabolism on Periodontitis Progression over Three Years.

Dent J (Basel) 2022 Jan 7;10(1). Epub 2022 Jan 7.

Department of Biostatistics and Epidemiology, Graduate School of Public Health, Medical Sciences Campus, University of Puerto Rico, San Juan 00936-5067, Puerto Rico.

We evaluated the relationship between glucose abnormalities and periodontitis in overweight/obese individuals. Eight hundred and seventy (870) diabetes-free participants aged 40-65 years completed the three-year follow-up in the San Juan Overweight Adults Longitudinal Study. The ADA thresholds for fasting and 2-h post-load glucose and HbA1c were used to define prediabetes. Read More

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January 2022

Self-Gelling Solid Lipid Nanoparticle Hydrogel Containing Simvastatin as Suitable Wound Dressing: An Investigative Study.

Gels 2022 Jan 13;8(1). Epub 2022 Jan 13.

University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India.

Hydrogels, an advanced interactive system, is finding use as wound dressings, however, they exhibit restricted mechanical properties, macroscopic nature, and may not manage high exudate wounds or incorporate lipophilic actives. In this study, we developed a self-gelling solid lipid nanoparticle (SLNs) dressing to incorporate simvastatin (SIM), a lipophilic, potential wound-healing agent, clinically limited due to poor solubility (0.03 mg/mL) and absorption. Read More

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January 2022

N-Heterocyclic-Carbene-Catalyzed C-H Acylation via Radical Relay.

Org Lett 2022 Jan 20. Epub 2022 Jan 20.

The College of Chemistry, Nanchang University, Nanchang, Jiangxi 330031, China.

A method of -fluorocarboxamide-directed N-heterocyclic-carbene (NHC)-catalyzed benzylic C-H acylation with aldehydes via the hydrogen atom transfer strategy is disclosed. This transformation involves a sequence of single-electron transfer, 1,5-hydrogen atom transfer, and radical cross-coupling steps. This method offers facile access to various highly functionalized ketones and exhibits good chemical yields and functional group tolerance. Read More

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January 2022

High-Power Bipolar Solid-State Batteries Enabled by In-Situ-Formed Ionogels for Vehicle Applications.

ACS Appl Mater Interfaces 2022 Jan 20. Epub 2022 Jan 20.

China Science Lab, General Motors Global Research & Development, Shanghai 201206, P. R. China.

Employing solid electrolytes (SEs) for lithium-ion batteries can boost the battery tolerance under abusive conditions and enable the implementation of bipolar cell stacking, leading to higher cell energy and power density as well as simplified thermal management. In this context, a bipolar solid-state battery (SSB) has received ever-increasing attention in recent years. However, poor solid-solid interfacial contact within the bipolar SSB deteriorates the battery power capability, representing a technical challenge for vehicle applications. Read More

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January 2022

OsCyp2-P, an auxin-responsive cyclophilin, regulates Ca calmodulin interaction for an ion-mediated stress response in rice.

Physiol Plant 2022 Jan 20:e13631. Epub 2022 Jan 20.

School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.

OsCYP2-P is an active cyclophilin (having peptidyl-prolyl cis/trans isomerase activity, PPIase) isolated from the wild rice Pokkali having a natural capacity to grow and yield seeds in coastal saline regions of India. Transcript abundance analysis in rice seedlings showed the gene is inducible by multiple stresses, including salinity, drought, high temperature, and heavy metals. To dissect the role of OsCYP2-P gene in stress response, we raised overexpression (OE) and knockdown (KD) transgenic rice plants with >2-3 folds higher and ~2-fold lower PPIase activity, respectively. Read More

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January 2022

Copper-catalyzed thiocarbonylation and thiolation of alkyl iodides.

Org Biomol Chem 2022 Jan 20. Epub 2022 Jan 20.

Key Laboratory of Agri-Food Safety of Anhui Province, School of Resources and Environment, Anhui Agricultural University, Hefei 230036, China.

In the present study, an efficient Cu-catalyzed transthiolation of alkyl iodides is developed. Notably, in the presence of CO, thioesters could also be obtained with copper and cobalt as the co-catalyst. This transformation displayed good functional group tolerance and afforded thioesters or sulfides from the corresponding alkyl iodides. Read More

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January 2022

Transdermal buprenorphine for in-hospital transition from full agonist opioids to sublingual buprenorphine: a retrospective observational cohort study.

Clin Toxicol (Phila) 2022 Jan 20:1-6. Epub 2022 Jan 20.

Department of Emergency Medicine, Division of Medical Toxicology, Washington University School of Medicine, St. Louis, MO, USA.

Introduction: Patients with opioid use disorder may have difficulty transitioning from full-agonist opioids to sublingual buprenorphine due to the risk of precipitated opioid withdrawal. Novel strategies have been developed to facilitate this transition, including the use of micro-dosing with transdermal buprenorphine. We began using a transdermal buprenorphine transition strategy at our hospital in 2019. Read More

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January 2022

Elucidating Drought-Tolerance Mechanisms in Plant Roots through H NMR Metabolomics in Parallel with MALDI-MS, and NanoSIMS Imaging Techniques.

Environ Sci Technol 2022 Jan 20. Epub 2022 Jan 20.

BIO5 Institute, The University of Arizona, 1657 East Helen Street., Tucson, Arizona 85719, United States.

As direct mediators between plants and soil, roots play an important role in metabolic responses to environmental stresses such as drought, yet these responses are vastly uncharacterized on a plant-specific level, especially for co-occurring species. Here, we aim to examine the effects of drought on root metabolic profiles and carbon allocation pathways of three tropical rainforest species by combining cutting-edge metabolomic and imaging technologies in an in situ position-specific C-pyruvate root-labeling experiment. Further, washed (rhizosphere-depleted) and unwashed roots were examined to test the impact of microbial presence on root metabolic pathways. Read More

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January 2022

[The Effect of Short-Term Intermittent Hypoxia Exposure on Mouse Myocardial Oxidative Stress and Cardiac Function].

Sichuan Da Xue Xue Bao Yi Xue Ban 2022 Jan;53(1):98-104

Laboratory of Mitochondria and Metabolism, Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, China.

Objective: To investigate the effect of short-term intermittent hypoxia (IH) on the structure and function of mouse myocardium.

Methods: Thirty male C57BL6/J mice were randomly assigned to two groups, a control (Con) group and an IH group exposed to hypoxic treatment at atmospheric pressure. The IH group received 10% oxygen pretreatment for 8 hours per day on 14 consecutive days, while the Con group was exposed to normoxia environment and all the other treatment the group received were identical to those given to the IH group, The body mass of the mice was monitored daily during the treatment. Read More

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January 2022

A novel leucine-rich repeat receptor-like kinase MRK1 regulates resistance to multiple stresses in tomato.

Hortic Res 2022 Jan 20. Epub 2022 Jan 20.

Department of Horticulture, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China.

Leucine-rich repeat receptor-like kinases (LRR-RLKs) are ubiquitous in higher plants, which act as receptors of extracellular signals to trigger multiple physiological processes. However, the functions of the majority of LRR-RLKs remain largely unknown, especially in tomato (Solanum lycopersicum L.). Read More

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January 2022

Association of severity of menstrual dysfunction with hyperinsulinemia and dysglycemia in polycystic ovary syndrome.

Hum Reprod 2022 Jan 20. Epub 2022 Jan 20.

Department of Obstetrics & Gynecology, and Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.

Study Question: Is the severity of menstrual cyclicity related to hyperinsulinemia and dysglycemia in women with hyperandrogenic polycystic ovary syndrome (PCOS)?

Summary Answer: Hyperandrogenic PCOS women with amenorrhea, compared to those with oligomenorrhea or eumenorrhea, had a greater risk of post-challenge hyperinsulinemia, which may explain their higher prevalence of dysglycemia.

What Is Known Already: PCOS is associated with metabolic dysregulation including insulin resistance (IR) and hyperinsulinemia, risk factors for type 2 diabetes mellitus (T2DM) and other vascular-metabolic morbidities. Although the severity of menstrual cyclicity is associated with IR in PCOS, it is unclear whether, and to what extent, it is related to hyperinsulinemia and glycemic abnormalities. Read More

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January 2022

Interfamily grafting capacity of petunia.

Hortic Res 2022 Jan 20. Epub 2022 Jan 20.

Bioscience and Biotechnology Center, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.

In grafting, an agricultural technique for propagating flower species and fruit trees, two plants are combined to exploit their beneficial characteristics, such as rootstock disease tolerance and vigor. Grafting incompatibility has been observed, however, between distantly related plant combinations, which limits the availability of plant resources. A high grafting capacity has been found in Nicotiana, belonging to Solanaceae, but not in Ipomoea nil, a Convolvulaceae species. Read More

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January 2022

An efficient root transformation system for CRISPR/Cas9-based analyses of shoot-root communication in cucurbit crops.

Hortic Res 2022 Jan 20. Epub 2022 Jan 20.

Key Laboratory of Horticultural Plant Biology, Ministry of Education, College of Horticulture and Forestry Sciences, Huazhong Agricultural University, Wuhan 430070, China.

Cucurbit crops are suitable models for studying long-distance signaling in horticultural plants. Although thousands of substances are graft transmissible in cucurbits, functional studies have been hampered by the lack of efficient genetic transformation systems. Here, we report a convenient and efficient root transformation method for several cucurbit crops that will facilitate studies of functional genes and shoot-root crosstalk. Read More

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January 2022

Inferring the Frank-Starling Curve From Simultaneous Venous and Arterial Doppler: Measurements From a Wireless, Wearable Ultrasound Patch.

Front Med Technol 2021 14;3:676995. Epub 2021 May 14.

Health Sciences North Research Institute, Sudbury, ON, Canada.

The Frank-Starling relationship is a fundamental concept in cardiovascular physiology, relating change in cardiac filling to its output. Historically, this relationship has been measured by physiologists and clinicians using invasive monitoring tools, relating right atrial pressure ( ) to stroke volume (SV) because the -SV slope has therapeutic implications. For example, a critically ill patient with a flattened -SV slope may have low yet fail to increase SV following additional cardiac filling (e. Read More

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Multiple Sclerosis: LIFNano-CD4 for Trojan Horse Delivery of the Neuro-Protective Biologic "LIF" Into the Brain: Preclinical Proof of Concept.

Front Med Technol 2021 7;3:640569. Epub 2021 Apr 7.

University of Cambridge Clinical School, LIFNanoRx Ltd, Cambridge, United Kingdom.

Multiple sclerosis (MS) is a demyelinating autoimmune disease that attacks the brain, with year-on-year loss of brain volume, starting late teens and becoming manifest late twenties. There is no cure, and current therapies are immunosuppressive only. LIF is a vital stem cell growth factor active throughout life-and essential for health of the central nervous system (CNS), being tolerogenic, myelinogenic, and neuroprotective. Read More

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Perceived Versus Verified Cancer History and Missed Opportunities for Donation in an Australian Cohort of Potential Deceased Solid Organ Donors.

Transplant Direct 2022 Feb 13;8(2):e1252. Epub 2022 Jan 13.

Collaborative Centre for Organ Donation Evidence, Sydney School of Public Health, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.

Background: There is an imperative to maximize donation opportunities given ongoing organ shortages, but donor suitability assessments can be challenging.

Methods: We analyzed an Australian cohort of potential deceased donors 2010 to 2013 to explore misclassification of cancer risk and potential strategies for improvement (decision support, real-time data linkage to existing data sets, and increasing risk tolerance). Cancer history perceived at referral was compared with verified cancer history in linked health records. Read More

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February 2022

Rapid Patient-Side Evaluation of Endothelial Glycocalyx Thickness in Healthy Sedated Cats Using GlycoCheck® Software.

Front Vet Sci 2021 3;8:727063. Epub 2022 Jan 3.

School of Veterinary Science, Massey University, Palmerston North, New Zealand.

The endothelial glycocalyx (EG) determines transvascular fluid fluxes, and influences inflammation, coagulation, and capillary blood flow. The GlycoCheck® software calculates EG thickness using sidestream dark field videomicroscopy recordings. This method has not been evaluated for use in cats. Read More

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January 2022

A Bibliometric Analysis of Endoscopic Sedation Research: 2001-2020.

Front Med (Lausanne) 2021 3;8:775495. Epub 2022 Jan 3.

Department of Anesthesiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

To evaluate endoscopic sedation research and predict research hot spots both quantitatively and qualitatively using bibliometric analysis. We extracted relevant publications from the Web of Science Core Collection (WoSCC) on 13 December 2020. We examined the retrieved data by bibliometric analysis (e. Read More

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January 2022