476 results match your criteria timing tempo

Characterization of pubertal development of girls in rural Bangladesh.

PLoS One 2021 2;16(4):e0247762. Epub 2021 Apr 2.

Center for Human Nutrition, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.

This study aimed to describe the timing and patterns of pubertal maturation of girls living in rural Bangladesh. Starting in September 2015, a total of 15,320 girls from a birth cohort, aged 9 to 15 years at initial encounter, were visited twice at about a one year interval, typically in their birth month. Participants were asked to self-report extent of pubertal maturation, including breast development, pubic hair growth and age at menarche, if applicable. Read More

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Production of regular rhythm induced by external stimuli in rats.

Anim Cogn 2021 Mar 22. Epub 2021 Mar 22.

Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan.

Rhythmic ability is important for locomotion, communication, and coordination between group members during the daily life of animals. We aimed to examine the rhythm perception and production abilities in rats within the range of a subsecond to a few seconds. We trained rats to respond to audio-visual stimuli presented in regular, isochronous rhythms at six time-intervals (0. Read More

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Identification of nutritionally modifiable hormonal and epigenetic drivers of positive and negative growth deviance in rural African fetuses and infants: Project protocol and cohort description.

Gates Open Res 2020 24;4:25. Epub 2020 Feb 24.

Department of Anthropology, University of Colorado, Boulder, CO, 80309, USA.

Growth retardation (stunting, wasting and poor organ development) among children in low-income countries has major short and long-term health consequences yet very little is known about the nutritional and environmental influences on the key hormonal axes regulating child growth in these settings, nor the tempo and timing of faltering episodes. Here we describe the study protocol and provide a cohort description of the Hormonal and Epigenetic Regulators of Growth (HERO-G) study. This prospective cohort study from rural Gambia, West Africa, followed mothers and children longitudinally from pre-conception, through pregnancy, delivery, and to two years of child age A total of 251 eligible mother-infant pairs were recruited into the HERO-G study, with 206 (82%) followed up until two years of age. Read More

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February 2020

Monkey see, monkey tap: mimicry of movement dynamics during coordinated tapping.

Exp Brain Res 2021 Mar 8. Epub 2021 Mar 8.

Department of Psychology, Michigan State University, East Lansing, MI, 48824, USA.

Common social behaviors, such as having a conversation, dancing, or playing a team sport, require precise interpersonal coordination of action. One question that emerges in research on interpersonal coordination is to what extent individuals implicitly mimic the spatial characteristics of movements for tasks that emphasize movement timing. To investigate this question, we conducted two experiments using an interpersonal synchronization-continuation tapping paradigm in which pairs of individuals tapped with their index finger on a table in synchrony with an auditory metronome and then continued tapping at the same tempo when the metronome stopped. Read More

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Girls' Pubertal Timing and Tempo and Mental Health: A Longitudinal Examination in an Ethnically Diverse Sample.

J Adolesc Health 2021 Feb 23. Epub 2021 Feb 23.

Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.

Purpose: Earlier timing and faster tempo of puberty have been linked to adolescents' poor mental health. Previous research rarely adjusted for childhood mental health, did not use physical examination to assess puberty, and excluded Latinas and Asian Americans. This study addressed these limitations. Read More

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February 2021

Attention Guides the Motor-Timing Strategies in Finger-Tapping Tasks When Moving Fast and Slow.

Front Psychol 2020 25;11:574396. Epub 2021 Jan 25.

University of Lille, CNRS, UMR 9193 - SCALab - Sciences Cognitives et Sciences Affectives, Lille, France.

Human beings adapt the spontaneous pace of their actions to interact with the environment. Yet, the nature of the mechanism enabling such adaptive behavior remains poorly understood. The aim of the present contribution was to examine the role of attention in motor timing using (a) time series analysis, and (b) a dual task paradigm. Read More

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January 2021

A general procedure to measure the pacing of body movements timed to music and metronome in younger and older adults.

Sci Rep 2021 Feb 5;11(1):3264. Epub 2021 Feb 5.

Univ. Lille, UMR 9193-SCALab-Sciences Cognitives et Sciences Affectives, 59000, Lille, France.

Finger-tapping tasks are classically used to investigate sensorimotor synchronization in relation to neutral auditory cues, such as metronomes. However, music is more commonly associated with an entrained bodily response, such as toe tapping, or dancing. Here we report an experimental procedure that was designed to bridge the gap between timing and intervention studies by directly comparing the effects of metronome and musical cue types on motor timing abilities across the three naturalistic voluntary actions of finger tapping, toe tapping, and stepping on the spot as a simplified case of whole body movement. Read More

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February 2021

Patterns and tempo of PCSK9 pseudogenizations suggest an ancient divergence in mammalian cholesterol homeostasis mechanisms.

Genetica 2021 Feb 30;149(1):1-19. Epub 2021 Jan 30.

Unit for Cardiac and Cardiovascular Genetics, Department of Medical Genetics, Oslo University Hospital, Nydalen, P.O. Box 4956, 0424, Oslo, Norway.

Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays a central role in cholesterol homeostasis in humans as a major regulator of LDLR levels. PCSK9 is an intriguing protease in that it does not act by proteolysis but by preventing LDLR recirculation from endosomes to the plasma membrane. This, and the inexistence of any other proteolytic substrate but itself could suggest that PCSK9 is an exquisite example of evolutionary fine-tuning. Read More

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February 2021

Longitudinal Associations of Pubertal Timing and Tempo With Adolescent Mental Health and Risk Behavior Initiation in Urban South Africa.

J Adolesc Health 2021 Jan 8. Epub 2021 Jan 8.

Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia. Electronic address:

Purpose: In high-income countries, early and rapid pubertal development is consistently associated with poor adjustment and increased risk behavior in adolescence. This study contributes to the meager knowledge of these associations in lower income countries.

Methods: We used longitudinal data from 1,784 urban black South Africans in the Birth to Twenty Plus cohort. Read More

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January 2021

Effects of Motor Tempo on Frontal Brain Activity: An fNIRS Study.

Neuroimage 2021 04 6;230:117597. Epub 2021 Jan 6.

Univ. Lille, UMR 9193 - SCALab - Sciences Cognitives et Sciences Affectives, F-59000 Lille, France. Electronic address:

People are able to modify the spontaneous pace of their actions to interact with their environment and others. This ability is underpinned by high-level cognitive functions but little is known in regard to the brain areas that underlie such temporal control. A salient practical issue is that current neuroimaging techniques (e. Read More

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Pubertal timing in boys and girls born to mothers with gestational diabetes mellitus: a systematic review.

Eur J Endocrinol 2021 Jan;184(1):51-64

Institute of Applied Health Research, University of Birmingham, Birmingham, UK.

Context: The incidence of gestational diabetes mellitus (GDM) has been on the rise, driven by maternal obesity. In parallel, pubertal tempo has increased in the general population, driven by childhood obesity.

Objective: To evaluate the available evidence on pubertal timing of boys and girls born to mothers with GDM. Read More

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January 2021

Pubertal timing and breast cancer risk in the Sister Study cohort.

Breast Cancer Res 2020 10 27;22(1):112. Epub 2020 Oct 27.

Epidemiology Branch, National Institute of Environmental Health Sciences, 111 TW Alexander Dr, Research Triangle Park, NC, 27709, USA.

Background: Earlier age at menarche is an established risk factor for breast cancer. While age at menarche has been fairly stable over the past half-century, age at breast development (thelarche) has continued to decrease. Recently, earlier age at thelarche and a longer time between thelarche and menarche (pubertal tempo) were shown to be associated with increased breast cancer risk. Read More

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October 2020

Molecular phylogenetics of Lotus (Leguminosae) with emphasis in the tempo and patterns of colonization in the Macaronesian region.

Mol Phylogenet Evol 2021 01 6;154:106970. Epub 2020 Oct 6.

Norwegian Institute of Bioeconomy Research, Høgskoleveien 8, 1433 Ås, Norway.

With a wide distribution range including Europe and Asia, Lotus (Leguminosae) represents the largest genus within Loteae. It is particularly diverse in the Mediterreanean region and in the five archipelagos of Macaronesia (Atlantic Ocean). However, little is known about the relationships among the 14 sections currently recognized within Lotus and about the timing and patterns of its colonization in the Macaronesian region. Read More

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January 2021

Conceptualizing attunement in dementia care: a meta-ethnographic review.

Arts Health 2020 Sep 30:1-17. Epub 2020 Sep 30.

Department of Communication and Psychology, Aalborg University , Aalborg, Denmark.

Background: Engagement in non-verbal communication positively influences well-being of persons with dementia, but requires good communication skills from caregivers. An important element of non-verbal communication is attunement, but even though communication is essential for persons experiencing severe cognitive decline, attunement has not been systematically examined in dementia care.

Method: A meta-ethnographic review was conducted to investigate the concept of attunement in dementia care. Read More

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September 2020

Birds advancing lay dates with warming springs face greater risk of chick mortality.

Proc Natl Acad Sci U S A 2020 10 28;117(41):25590-25594. Epub 2020 Sep 28.

Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY 14853.

In response to a warming planet with earlier springs, migratory animals are adjusting the timing of essential life stages. Although these adjustments may be essential for keeping pace with resource phenology, they may prove insufficient, as evidenced by population declines in many species. However, even when species can match the tempo of climate change, other consequences may emerge when exposed to novel conditions earlier in the year. Read More

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October 2020

Maturity-associated considerations for training load, injury risk, and physical performance in youth soccer: One size does not fit all.

J Sport Health Sci 2020 Sep 19. Epub 2020 Sep 19.

School of Health Sciences, Liverpool Hope University, Liverpool, 16 9JD, UK.

Biological maturation can be defined as the timing and tempo of progress to achieving a mature state. The estimation of age of peak height velocity (PHV) or percentage of final estimated adult stature attainment (%EASA) is typically used to inform the training process in young athletes. In youth soccer, maturity-related changes in anthropometric and physical fitness characteristics are diverse among individuals, particularly around PHV. Read More

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September 2020

β-catenin signaling modulates the tempo of dendritic growth of adult-born hippocampal neurons.

EMBO J 2020 11 15;39(21):e104472. Epub 2020 Sep 15.

Institute of Biochemistry, Emil Fischer Center, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.

In adult hippocampal neurogenesis, stem/progenitor cells generate dentate granule neurons that contribute to hippocampal plasticity. The establishment of a morphologically defined dendritic arbor is central to the functional integration of adult-born neurons. We investigated the role of canonical Wnt/β-catenin signaling in dendritogenesis of adult-born neurons. Read More

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November 2020

The influence of performing gesture type on interpersonal musical timing, and the role of visual contact and tempo.

Acta Psychol (Amst) 2020 Oct 9;210:103166. Epub 2020 Sep 9.

IPEM, Dept. of Art, Music and Theatre Sciences, Ghent University, Miriam Makebaplein 1, 9000 Ghent, Belgium.

Bodily gestures play an important role in the communication of expressive intentions between humans. Music ensemble performance, as an outstanding example of nonverbal human communication, offers an exemplary context to study and understand the gestural control and communication of these expressive intentions. An important mechanism in music ensemble performance is the anticipation and control of interpersonal timing. Read More

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October 2020

Pubertal Synchrony and Depressive Symptoms: Differences by Race and Sex.

J Youth Adolesc 2020 Nov 9;49(11):2275-2284. Epub 2020 Sep 9.

Department of Psychology, Temple University, Philadelphia, PA, USA.

Individual differences in the timing and tempo of pubertal development have been shown to be related to depressive symptoms during adolescence, particularly among girls. Another measure of variability in pubertal development is pubertal synchrony, the degree to which the development of pubertal indicators (e.g. Read More

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November 2020

[Predictive effects of pubertal timing and tempo on adolescent depressive symptoms: a 6-year prospective cohort study].

Zhonghua Yu Fang Yi Xue Za Zhi 2020 Jul;54(7):747-752

Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei 230032, China.

To examine the prospective association of pubertal timing and tempo with depressive symptoms in adolescents. Since 2013, 2 084 students in grade 1-3 were selected from two primary schools in Bengbu, Anhui Province were selected by using convenience sampling method to establish the adolescence pubertal development cohort. Followed up for 6 years, physical examination, secondary sexual development evaluation (testicular volume for boys and breast development for girls) and depressive symptoms were evaluated biennially. Read More

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Prion-associated cerebral amyloid angiopathy is not exacerbated by human phosphorylated tau aggregates in scrapie-infected mice expressing anchorless prion protein.

Neurobiol Dis 2020 10 21;144:105057. Epub 2020 Aug 21.

Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South Fourth Street, Hamilton, MT 59840, USA.

Tau aggregates consisting of hyperphosphorylated tau fibrils are associated with many neurodegenerative diseases, including Alzheimer's disease, Pick's disease, frontotemporal dementia, and progressive supranuclear palsy. Tau may contribute to the pathogenesis of these diseases, collectively referred to as tauopathies. In human genetic prion diseases, tau aggregates are detected in association with amyloid plaques consisting of prion protein (PrP). Read More

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October 2020

Human adaptation over the past 40,000 years.

Iain Mathieson

Curr Opin Genet Dev 2020 06 1;62:97-104. Epub 2020 Aug 1.

Department of Genetics, Perelman School of Medicine, University of Pennsylvania, United States. Electronic address:

Over the past few years several methodological and data-driven advances have greatly improved our ability to robustly detect genomic signatures of selection in humans. New methods applied to large samples of present-day genomes provide increased power, while ancient DNA allows precise estimation of timing and tempo. However, despite these advances, we are still limited in our ability to translate these signatures into understanding about which traits were actually under selection, and why. Read More

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Working time dimensions and well-being: a cross-national study of Finnish and German health care employees.

Chronobiol Int 2020 Sep-Oct;37(9-10):1312-1324. Epub 2020 Jul 29.

Finnish Institute of Occupational Health, Work Ability and Working Careers, Helsinki, Finland.

Health care professionals often face irregular working hours and high work pace. We studied associations of the five working time dimensions duration (weekly working hours), timing (shift work and weekend work), on-call work, working time autonomy, and work tempo (deadline and performance pressure) with well-being among health care employees in Finland and Germany. We used data on working time dimensions and indicators of well-being (work-life conflict, poor perceived health, sleep difficulties, and fatigue) from a cohort of 5050 hospital employees (Working Hours in the Finnish Public Sector Study 2015, WHFPS) and 1450 employees in the health care sector in Germany responding to the German BAuA-Working Time Survey in 2015 (BAuA-WTS). Read More

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Weathering, alteration and reconstructing Earth's oxygenation.

Interface Focus 2020 Aug 12;10(4):20190140. Epub 2020 Jun 12.

Department of Geosciences, Eberhard-Karls University of Tuebingen, Tuebingen, Germany.

Deciphering the role-if any-that free oxygen levels played in controlling the timing and tempo of the radiation of complex life is one of the most fundamental questions in Earth and life sciences. Accurately reconstructing Earth's redox history is an essential part of tackling this question. Over the past few decades, there has been a proliferation of research employing geochemical redox proxies in an effort to tell the story of Earth's oxygenation. Read More

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The interplay of interval models and entrainment models in duration perception.

J Exp Psychol Hum Percept Perform 2020 Oct 2;46(10):1088-1104. Epub 2020 Jul 2.

Department of Cognitive Science.

Despite extensive research demonstrating the effect of temporal context on time perception, its underlying mechanisms remain poorly understood. One influential proposal to explain the temporal context effect is McAuley and Jones' (2003) framework that incorporates 2 classic timing models, interval and entrainment models. They demonstrated that listeners' duration estimates were shifted from reality in opposite directions when to-be-judged durations occurred earlier versus later than an expected beat, which is predicted by their entrainment models. Read More

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October 2020

Spontaneous and stimulus-driven rhythmic behaviors in ADHD adults and controls.

Neuropsychologia 2020 09 26;146:107544. Epub 2020 Jun 26.

The Gonda Brain Research Center, Bar Ilan University, Ramat Gan, Israel. Electronic address:

Many aspects of human behavior are inherently rhythmic, requiring production of rhythmic motor actions as well as synchronizing to rhythms in the environment. It is well-established that individuals with ADHD exhibit deficits in temporal estimation and timing functions, which may impact their ability to accurately produce and interact with rhythmic stimuli. In the current study we seek to understand the specific aspects of rhythmic behavior that are implicated in ADHD. Read More

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September 2020

Childhood Adversity and Pubertal Development Among Puerto Rican Boys and Girls.

Psychosom Med 2020 06;82(5):487-494

From the Department of Epidemiology, Rollins School of Public Health (Suglia, Cammack), Emory University, Atlanta, Georgia; Department of Psychiatry, New York State Psychiatric Institute (Chen, McGlinchey, Bird, Duarte), and Departments of Biostatistics (Wang) and Epidemiology (April-Sanders), Mailman School of Public Health, Columbia University, New York, New York; School of Psychology (McGlinchey), Fairleigh Dickinson University, Teaneck, New Jersey; Kaiser Permanente Division of Research (Kubo), Oakland, California; and Behavioral Science Research Institute (Canino), University of Puerto Rico, San Juan, Puerto Rico.

Objective: Evidence stemming largely from retrospective studies suggests that childhood adversity (CA) is associated with earlier age at menarche, a marker of pubertal timing, among girls. Little is known about associations with pubertal tempo among boys or racial/ethnic minorities. We examined the association between CA and timing and tempo of pubertal development among boys and girls. Read More

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Sociodemographic predictors of early postnatal growth: evidence from a Chilean infancy cohort.

BMJ Open 2020 06 3;10(6):e033695. Epub 2020 Jun 3.

Department of Nutrition and UNC Nutrition Research Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Objectives: Infant anthropometric growth varies across socioeconomic factors, including maternal education and income, and may serve as an indicator of environmental influences in early life with long-term health consequences. Previous research has identified sociodemographic gradients in growth with a focus on the first year and beyond, but estimates are sparse for growth before 6 months. Thus, our objective was to examine the relationship between sociodemographic factors and infant growth patterns between birth and 5 months of age. Read More

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Pubertal Development: What's Normal/What's Not.

Clin Obstet Gynecol 2020 09;63(3):491-503

Division of Adolescent and Transition Medicine, Cincinnati Children's Hospital Medical Center.

Onset of puberty, as defined by breast stage 2, appears to be starting at younger ages since the 1940s. There is an ongoing controversy regarding what is normative, as well as what is normal, and the evaluation that is deemed necessary for girls maturing before 8 years of age. There are potential implications of earlier pubertal timing, including psychosocial consequences during adolescence, as well as longer term risks, such as breast cancer and cardiometabolic risks. Read More

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September 2020

Basic timekeeping deficit in the Beat-based Form of Congenital Amusia.

Sci Rep 2020 05 20;10(1):8325. Epub 2020 May 20.

International Laboratory for Brain, Music, and Sound Research, Montréal, Québec, H3C 3J7, Canada.

Humans have the capacity to match movements' timing with the beat of music. Yet some individuals show marked difficulties. The causes of these difficulties remain to be determined. Read More

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