Analyst 2021 May 4. Epub 2021 May 4.
Joint Mass Spectrometry Centre, Chair of Analytical Chemistry, University of Rostock, 18059 Rostock, Germany. and Joint Mass Spectrometry Centre, Cooperation Group "Comprehensive Molecular Analytics" (CMA), Helmholtz Zentrum München, 81379 München, Germany.
We developed a novel fast gas chromatography (fastGC) instrument with integrated sampling of volatile organic compounds (VOCs) and detection by single-photon ionisation (SPI) time-of-flight mass spectrometry (TOFMS). A consumable-free electrical modulator rapidly cools down to -55 °C to trap VOCs and inject them on a short chromatographic column by prompt heating to 300 °C, followed by carrier gas exchange from air to helium. Due to the low thermal mass and optical heating, the fastGC is operated within total runtimes including cooling for 30 s and 15 s, referring to hyper-fast GC, and at a constantly increasing temperature ramp from 30 °C to 280 °C. Read More