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Effects of omega 3 polyunsaturated fatty acids, antioxidants and/or non-steroidal inflammatory drugs in the brain of neonatal rats exposed to intermittent hypoxia.

Int J Dev Neurosci 2021 May 9. Epub 2021 May 9.

Department of Pediatrics, Division of Neonatal-Perinatal Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY, 11203, USA.

Preterm infants experience frequent arterial oxygen desaturations during oxygen therapy, or intermittent hypoxia (IH). Neonatal IH increases oxidative distress which contributes to neuroinflammation and brain injury. We tested the hypotheses that exposure to neonatal IH is detrimental to the immature brain, and that early supplementation with antioxidants and/or omega 3 polyunsaturated fatty acids (n-3 PUFAs) combined with non-steroidal anti-inflammatory drugs (NSAIDs) is protective. Read More

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Elucidating ROS signaling networks and physiological changes involved in nanoscale zero valent iron primed rice seed germination sensu stricto.

Free Radic Biol Med 2021 May 6. Epub 2021 May 6.

Centre of Advanced Study, Department of Botany, Calcutta University, 35, Ballygange Circular Road, Kolkata-19, India. Electronic address:

Reactive oxygen species (ROS) play pivotal roles during seed dormancy and germination. Metabolically active cells of seeds generate ROS and successful germination is governed by internal ROS contents, maintained within an optimum "oxidative window" by several ROS scavengers. Although ROS was previously considered hazardous, optimum ROS generation in seeds can mediate early seed germination by acting as messengers for cell signaling involved in endosperm weakening, stored food mobilization, etc. Read More

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Decoding the microstructural properties of white matter using realistic models.

Neuroimage 2021 May 5:118138. Epub 2021 May 5.

Radboud University, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands.

Multi-echo gradient echo (ME-GRE) magnetic resonance signal evolution in white matter has a strong dependence on the orientation of myelinated axons with respect to the main static field. Although analytical solutions have been able to predict some of the white matter (WM) signal behaviour of the hollow cylinder model, it has been shown that realistic models of WM offer a better description of the signal behaviour observed. In this work, we present a pipeline to (i) generate realistic 2D WM models with their microstructure based on real axon morphology with adjustable fiber volume fraction (FVF) and g-ratio. Read More

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Predictors of Traumatic Nerve Injury and Nerve Recovery following Humeral Shaft Fractures: Short title: Traumatic Nerve Palsy after Humeral Shaft Fracture.

J Shoulder Elbow Surg 2021 May 5. Epub 2021 May 5.

Department of Orthopaedic Surgery, MetroHealth Medical Center, Cleveland, OH, USA. Electronic address:

Introduction: Nerve palsy is common after humeral shaft fracture with the radial nerve being the most commonly injured nerve. Isolated nerve injuries usually recover spontaneously and operative intervention is rarely indicated. Our goal was to study the predictors of traumatic nerve injury and recovery in a large cohort of patients with humeral shaft fractures. Read More

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3-month, 6-month, 9-month, and 12-month respiratory outcomes in patients following COVID-19-related hospitalisation: a prospective study.

Lancet Respir Med 2021 May 5. Epub 2021 May 5.

Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK; Institute for Life Sciences, University of Southampton, Southampton, UK; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, UK. Electronic address:

Background: The consequences of COVID-19 in those who recover from acute infection requiring hospitalisation have yet to be clearly defined. We aimed to describe the temporal trends in respiratory outcomes over 12 months in patients hospitalised for severe COVID-19 and to investigate the associated risk factors.

Methods: In this prospective, longitudinal, cohort study, patients admitted to hospital for severe COVID-19 who did not require mechanical ventilation were prospectively followed up at 3 months, 6 months, 9 months, and 12 months after discharge from Renmin Hospital of Wuhan University, Wuhan, China. Read More

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Long-term follow-up after acute achilles tendon rupture - Does treatment strategy influence functional outcomes?

Foot (Edinb) 2021 Jan 13;47:101769. Epub 2021 Jan 13.

Orthopaedic Research Unit, Aalborg University Hospital, Aalborg, Denmark; Physiotherapy and Occupational Therapy, Aalborg University Hospital, Aalborg, Denmark; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address:

Background: Patients struggle to fully recover after an Achilles tendon rupture. Although several studies has investigated surgical and non-surgical treatment, the best treatment is still uncertain. The aim of this study was to investigate long-term patient-reported outcomes and objective measures 4 years after acute Achilles tendon rupture and compare whether outcomes differed between patients treated on basis of the previous regimen preferring surgical treatment and the new regimen preferring functional rehabilitation. Read More

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January 2021

Connecting With Trauma Patients After Discharge: A Phone Call Follow-Up Study.

J Trauma Nurs 2021 May-Jun 01;28(3):179-185

Royal North Shore Hospital, Sydney, New South Wales, Australia.

Background: Traumatic injury is sudden and unexpected. It may lead to long-standing physical and physiological consequences. Approximately 10% of the world's disease burden is attributable to traumatic injuries. Read More

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Bladder management in children with transverse myelitis.

J Pediatr Urol 2021 Apr 21. Epub 2021 Apr 21.

Department of Pediatric Urology, Children's Medical Center, Dallas, TX, USA. Electronic address:

Background: Patients with transverse myelitis (TM) often present with urinary retention. While many recover their bladder function, some have persistent voiding dysfunction, and both intermediate and long-term outcomes are variable.

Objective: In patients who develop urinary retention requiring clean intermittent catheterization (CIC) at onset of TM, we sought to assess factors associated with improved voiding function and the risk of requiring persistent CIC over time. Read More

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Water immersion tolerance by larval instars of stable fly, Stomoxys calcitrans, L1758 (Diptera: Muscidae) impairs the fitness performance of their subsequent stages.

Steve B S Baleba

BMC Ecol Evol 2021 May 4;21(1):78. Epub 2021 May 4.

International Centre of Insect Physiology and Ecology (icipe), P.O. Box 30772-00100, Nairobi, Kenya.

Background: In holometabolous insects, environmental factors experienced in pre-imaginal life stages affect the life-history traits within that stage and can also influence subsequent life stages. Here, I assessed tolerance to water immersion by the larval instars of the stable fly, Stomoxys calcitrans L. (Diptera: Muscidae) and its impact on the life-history traits of their subsequent life stages. Read More

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Effects of whitening toothpaste and bleaching treatment on resin composite discoloration caused by cigarette smoke and electronic vapor aerosol.

Am J Dent 2021 Apr;34(2):63-69

University of Rochester Eastman Institute for Oral Health, Rochester, NY, USA,

Purpose: To compare the effects of whitening toothpaste and bleaching with 6% hydrogen peroxide (H2O2) on discoloration of dental resin composite caused by cigarette smoke (CS) and electronic vapor product (EVP) aerosol.

Methods: 40 resin composite discs were divided into three groups: 15 each for CS and EVP aerosol exposure and 10 for air exposure (control). Exposures were performed for 15 days, with daily brushing with regular toothpaste. Read More

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Sustainable recovery of neodymium and dysprosium from waters through seaweeds: Influence of operational parameters.

Chemosphere 2021 Apr 16;280:130600. Epub 2021 Apr 16.

Department of Chemistry, University of Aveiro, Aveiro, Portugal; LAQV-REQUIMTE - Associated Laboratory for Green Chemistry, University of Aveiro, Aveiro, Portugal; LCA - Central Laboratory of Analysis, University of Aveiro, Aveiro, Portugal.

The high demand for greener energy and technological innovation require some crucial elements, such as the rare earths Nd and Dy. Being considered two of the most critical elements (high supply risk), it is vital to recover them from wastes/wastewaters, for later reuse. Here, the influence of operational parameters, such as biosorbent stock density (0. Read More

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Transient dynamics during kelp forest recovery from fishing across multiple trophic levels.

Ecol Appl 2021 May 3:e2367. Epub 2021 May 3.

Department of Environmental Science and Policy, University of California Davis, Davis.

Outcomes of management efforts to recover or restore populations of harvested species can be highly dependent on environmental and community context. Predator-prey interactions can alter recovery trajectories, and the timing of management actions within multi-trophic level harvest scenarios may influence the dynamics of recovery and lead to management trade-offs. Recent work using a generalist predator-prey model suggests that management promoting synchronized recovery of predators and prey leads to faster and less variable recovery trajectories than sequential recovery (predator- or prey-first). Read More

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Developing a Multi-channel Beamformer by Enhancing Spatially Constrained ICA for Recovery of Correlated EEG Sources.

J Biomed Phys Eng 2021 Apr 1;11(2):205-214. Epub 2021 Apr 1.

MD, Iranian Centre of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.

Background: Brain source imaging based on electroencephalogram (EEG) data aims to recover the neuron populations' activity producing the scalp potentials. This procedure is known as the EEG inverse problem. Recently, beamformers have gained a lot of consideration in the EEG inverse problem. Read More

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The Relationship of Magnesium Level with the Recovery of Parathyroid Function in Post-thyroidectomy Hypoparathyroidism.

Sisli Etfal Hastan Tip Bul 2021 17;55(1):33-41. Epub 2021 Mar 17.

Department of General Surgery, University of Health Sciences Turkey, Sisli Hamidiye Etfal Teaching and Research Hospital, Istanbul, Turkey.

Objectives: Hypocalcemia is the most common complication and acute parathyroid gland insufficiency is the main cause of it after thyroidectomy. In this study, we aimed to evaluate the relationship between the recovery time of parathyroid gland function and patient characteristics, preoperative and postoperative electrolyte changes, and intraoperative parathyroid findings in patients with postoperative hypoparathyroidism.

Methods: Patients who underwent total thyroidectomy (TT) with or without central neck dissection ± lateral neck dissection with a parathyroid hormone (PTH) value of <15 pg/mL within the postoperative 4th hour were included in this study. Read More

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Magnetic Fluid Hyperthermia as Treatment Option for Pancreatic Cancer Cells and Pancreatic Cancer Organoids.

Int J Nanomedicine 2021 23;16:2965-2981. Epub 2021 Apr 23.

Department of General, Visceral and Transplant Surgery, RWTH Aachen University Hospital, Aachen, Germany.

Introduction: Pancreatic ductal adenocarcinoma (PDAC) is a cancer with a meager prognosis due to its chemotherapy resistance. A new treatment method may be magnetic fluid hyperthermia (MFH). Magnetoliposomes (ML), consisting of superparamagnetic iron oxide nanoparticles (SPION) stabilized with a phospholipid-bilayer, are exposed to an alternating magnetic field (AMF) to generate heat. Read More

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Molecular detection and identification of and spp. in one-humped camel () breeds in Egypt.

Vet World 2021 Mar 12;14(3):625-633. Epub 2021 Mar 12.

Department of Animal Medicine, Faculty of Veterinary Medicine, Aswan University, Aswan, 37916, Egypt.

Background And Aim: Camels are a unique source of milk and meat, which helps recover from several diseases that affect humans worldwide. In Egypt, one of the great obstacles for this industry is tick-borne diseases. This study aimed to characterize blood parasite infections, such as (. Read More

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Performance Validity Testing in Patients Presenting to a Specialty Clinic With a Mild Traumatic Brain Injury.

J Head Trauma Rehabil 2021 Apr 30. Epub 2021 Apr 30.

Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (Drs Sherry, Ernst, French, and Collins); and Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania (Drs Sherry, French, Eagle, Collins, and Kontos).

Objective: To evaluate predictors of performance validity testing (PVT) and clinical outcome in patients presenting to a specialty clinic with a mild traumatic brain injury (mTBI).

Setting: An outpatient mTBI specialty clinic.

Participants: Seventy-six (47% female) patients aged 16 to 66 (mean = 40. Read More

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The effect of neomycin inclusion in milk replacer on the health, growth, and performance of male Holstein calves during preweaning.

J Dairy Sci 2021 Apr 29. Epub 2021 Apr 29.

Department of Animal Biosciences, Animal Science and Nutrition, University of Guelph, Guelph, Ontario, Canada N1G 1Y2. Electronic address:

The prophylactic use of oral antimicrobials, such as neomycin, in milk replacer (MR) or whole milk is a common practice in calf-rearing that is thought to aid in preventing disease. Heavy reliance on antimicrobials is of concern not only because of the development of antimicrobial resistance, but also because of the potentially negative effects on health. The objective of this study was to investigate the effects of neomycin on calf health and growth performance. Read More

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Capacity of an ecologically key urchin to recover from extreme events: Physiological impacts of heatwaves and the road to recovery.

Sci Total Environ 2021 Apr 23;785:147281. Epub 2021 Apr 23.

The Swire Institute of Marine Science and School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China. Electronic address:

Heatwaves are increasing in frequency and intensity, with substantial impacts on ecosystems and species which maintain their function. Whether or not species are harmed by heatwave conditions by being pushed beyond their physiological bounds can depend on whether energy replacement is sufficient to enable recovery from acute stress. We exposed an ecologically important sea urchin, Heliocidaris erythrogramma, to experimental marine heatwave scenarios in context with recent summer heat anomalies in moderate (25 °C), and strong heatwave (26 °C) conditions for 10 days, followed by a 10-day recovery period at normal summer temperature (23 °C). Read More

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Comprehensive recovery of arsenic and antimony from arsenic-rich copper smelter dust.

J Hazard Mater 2021 Jul 9;413:125365. Epub 2021 Feb 9.

College of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, China.

In view of reducing contaminant and recovery arsenic and antimony, a novel technology was proposed to recover arsenic and antimony from arsenic-rich copper smelter dust comprehensively. The technique route includes three stages: arsenic and antimony trioxides were leached from the copper smelter dust with hydrochloric acid; trivalent arsenic ions (As) were then reduced to less toxic simple arsenic (As) by sodium hypophosphate (NaHPO) and recovered; and stepwise recovery of antimony by SbCl was achieved by the continuous distillation technique. The results indicates that the leaching efficiency of As and Sb was over 97. Read More

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Efficient Route Management Method for Mobile Nodes in 6TiSCH Network.

Sensors (Basel) 2021 Apr 28;21(9). Epub 2021 Apr 28.

Department of Information Convergence Engineering, Pusan National University, Busan 46241, Korea.

The combination of time slotted access and channel hopping technology in IEEE 802.15 TSCH networks enables high reliability and low power operation to meet the stability and real-time requirements of industrial applications. Basically, TSCH and RPL, a routing protocol for TSCH, are proposed for static nodes that generate fewer control messages, so they allow collisions in shared cells when they exchange control messages. Read More

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A Hybrid Visual Tracking Algorithm Based on SOM Network and Correlation Filter.

Sensors (Basel) 2021 Apr 19;21(8). Epub 2021 Apr 19.

College of Computer & Information Science, Southwest University, Chongqing 400715, China.

To meet the challenge of video target tracking, based on a self-organization mapping network (SOM) and correlation filter, a long-term visual tracking algorithm is proposed. Objects in different videos or images often have completely different appearance, therefore, the self-organization mapping neural network with the characteristics of signal processing mechanism of human brain neurons is used to perform adaptive and unsupervised features learning. A reliable method of robust target tracking is proposed, based on multiple adaptive correlation filters with a memory function of target appearance at the same time. Read More

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Zebrafish Optomotor Response and Morphology Are Altered by Transient, Developmental Exposure to Bisphenol-A.

J Dev Biol 2021 Apr 2;9(2). Epub 2021 Apr 2.

Department of Biology, American University, 4400 Massachusetts Ave NW, Washington, DC 20016, USA.

Estrogen-specific endocrine disrupting compounds (EDCs) are potent modulators of neural and visual development and common environmental contaminants. Using zebrafish, we examined the long-term impact of abnormal estrogenic signaling by testing the effects of acute, early exposure to bisphenol-A (BPA), a weak estrogen agonist, on later visually guided behaviors. Zebrafish aged 24 h postfertilization (hpf), 72 hpf, and 7 days postfertilization (dpf) were exposed to 0. Read More

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Molecular Biomechanics Controls Protein Mixing and Segregation in Adherent Membranes.

Int J Mol Sci 2021 Apr 2;22(7). Epub 2021 Apr 2.

PULS Group, Institute for Theoretical Physics and Interdisciplinary Center for Nanostructured Films, Friedrich-Alexander-University Erlangen-Nürnberg, Cauerstrasse 3, 91058 Erlangen, Germany.

Cells interact with their environment by forming complex structures involving a multitude of proteins within assemblies in the plasma membrane. Despite the omnipresence of these assemblies, a number of questions about the correlations between the organisation of domains and the biomechanical properties of the involved proteins, namely their length, flexibility and affinity, as well as about the coupling to the elastic, fluctuating membrane, remain open. Here we address these issues by developing an effective Kinetic Monte Carlo simulation to model membrane adhesion. Read More

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Clinical Analysis for Long-Term Sporadic Bovine Viral Diarrhea Transmitted by Calves with an Acute Infection of Bovine Viral Diarrhea Virus 2.

Viruses 2021 04 4;13(4). Epub 2021 Apr 4.

Division of Pathology and Pathophysiology, Hokkaido Research Station, National Institute of Animal Health, NARO, Sapporo, Hokkaido 062-0045, Japan.

Bovine viral diarrhea virus (BVDV) is a viral pathogen associated with serious problems in the cattle industry. Cattle persistently infected (PI) with BVDV are mild or asymptomatic; however, they become a source of BVDV transmission to other cattle. Hence, it is important to rapidly identify and remove the PI animals from cattle herds. Read More

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Hydrochemical changes of a spring due to the May 30, 2014 Ms 6.1 Yingjiang earthquake, southwest China.

Environ Pollut 2021 Apr 17;284:117125. Epub 2021 Apr 17.

State Key Laboratory of Biogeology and Environmental Geology & MOE Key Laboratory of Groundwater Circulation and Environmental Evolution, China University of Geosciences, Beijing, 100083, China; School of Water Resources and Environment, China University of Geosciences, Beijing, 100083, China. Electronic address:

Groundwater chemistry can be affected by and related to earthquakes, thus it is crucial to understand the hydrochemical changes and associated processes caused by earthquakes for post-seismic groundwater utilization. Here we reported the major ion concentrations changes of the Ganze Spring in response to the May 30, 2014 Ms 6.1 Yingjiang earthquake, southwest China based on the daily time series (from 1st January 2012 to 20th July 2014) of Ca, Mg and HCO concentrations, as well as data of bulk strain and Peak Ground Velocity (PGV) recorded at a nearby station. Read More

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Stress testing and myocardial perfusion imaging for patients after recovery from severe COVID-19 infection requiring hospitalization: A single-center experience.

J Nucl Cardiol 2021 Apr 26. Epub 2021 Apr 26.

Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, LHRB 326, 701 19th Street South, Birmingham, AL, 35294, USA.

Background: As the coronavirus pandemic progresses, patients that have recovered from COVID-19-related hospitalization require resumption of care for other medical issues. Thus far, the literature has not detailed the experience of stress testing in this patient population.

Methods: We retrospectively reviewed patients that recovered from COVID-19-related hospitalizations and underwent SPECT MPI studies at the University of Alabama at Birmingham Medical Center. Read More

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Shape Memory Alloy (SMA) Actuator With Embedded Liquid Metal Curvature Sensor for Closed-Loop Control.

Front Robot AI 2021 11;8:599650. Epub 2021 Mar 11.

Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA, United States.

We introduce a soft robot actuator composed of a pre-stressed elastomer film embedded with shape memory alloy (SMA) and a liquid metal (LM) curvature sensor. SMA-based actuators are commonly used as electrically-powered limbs to enable walking, crawling, and swimming of soft robots. However, they are susceptible to overheating and long-term degradation if they are electrically stimulated before they have time to mechanically recover from their previous activation cycle. Read More

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Guidance on date marking and related food information: part 2 (food information).

EFSA J 2021 Apr 22;19(4):e06510. Epub 2021 Apr 22.

A risk-based approach was used to develop guidance to be followed by food business operators (FBOs) when deciding on food information relating to storage conditions and/or time limits for consumption after opening a food package and thawing of frozen foods. After opening the package, contamination may occur, introducing new pathogens into the food and the intrinsic (e.g. Read More

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Analysis of voice changes after thyroidectomy using the thyroidectomy-related voice and symptom questionnaire.

Auris Nasus Larynx 2021 Apr 22. Epub 2021 Apr 22.

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address:

Objective: After thyroidectomy, many patients suffer from voice problems and vague neck discomfort. The Thyroidectomy-related Voice and Symptom Questionnaire (TVSQ) is a self-administered questionnaire used to evaluate pre- and post-operative vocal status as well as throat and neck discomfort. We investigated voice conditions in thyroidectomy patients using the TVSQ as well as correlations between TVSQ responses and objective voice parameters. Read More

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