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Assessment of patients' cumulative doses in one year and collective dose to population through CT examinations.

Eur J Radiol 2021 Jul 22;142:109871. Epub 2021 Jul 22.

Centre de recherche du Centre hospitalier universitaire de Sherbrooke (CRCHUS), Sherbrooke, Québec, Canada; Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre hospitalier universitaire de Sherbrooke (CIUSSS de l'Estrie - CHUS), Sherbrooke, Québec, Canada; Department of Nuclear Medicine and Radiobiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Canada.

Purpose: To estimate percentage of patients undergoing multiple CT exams leading to cumulative effective dose (CED) of more than 25, 50, 75 and 100 mSv in one year and assess per capita and the collective effective dose.

Methods: Data from a regional hospital network was collected retrospectively using radiation dose monitoring system at 6 facilities with 8 CT scanners. The data was analyzed to find number of patients in different dose groups, their age, gender, number of CT exams and exams needed to reach 100 mSv based on age groups. Read More

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Geographic barriers to achieving universal health coverage: evidence from rural Madagascar.

Health Policy Plan 2021 Jul 31. Epub 2021 Jul 31.

NGO PIVOT, BP23 Ranomafana, 312 Ifanadiana, Madagascar.

Poor geographic access can persist even when affordable and well-functioning health systems are in place, limiting efforts for universal health coverage (UHC). It is unclear how to balance support for health facilities and community health workers in UHC national strategies. The goal of this study was to evaluate how a health system strengthening (HSS) intervention aimed towards UHC affected the geographic access to primary care in a rural district of Madagascar. Read More

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Trends in healthcare utilisation during COVID-19: a longitudinal study from the UK.

BMJ Open 2021 Jul 30;11(7):e048151. Epub 2021 Jul 30.

Cigna Europe, Greenock, UK.

Objective: The first wave of the COVID-19 pandemic had a major impact on healthcare utilisation. The aim of this retrospective review was to quantify how utilisation of non-COVID care changed during this time so as to gain insight and inform planning of future services during potential second and subsequent waves.

Methods And Analysis: A longitudinal design was used to analyse anonymous private UK health insurer datasets covering the period of January 2018 to August 2020. Read More

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Real-world implementation of video-observed therapy in an urban TB program in the United States.

Int J Tuberc Lung Dis 2021 Aug;25(8):655-661

Division of Infectious Diseases, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Video directly observed therapy (vDOT) was introduced to increase flexibility and meet patient-specific needs for TB treatment. This study aimed to assess the reach and effectiveness of vDOT for TB treatment under routine conditions in Alameda County, CA, USA, a busy, urban setting, from 2018 to 2020. We prospectively evaluated routinely collected data to estimate 1) reach (proportion of patients initiated on vDOT vs. Read More

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A particle swarm optimization improved BP neural network intelligent model for electrocardiogram classification.

BMC Med Inform Decis Mak 2021 Jul 30;21(Suppl 2):99. Epub 2021 Jul 30.

Department of Biomedical Engineering, School of Material Science and Engineering, South China University of Technology, Guangzhou, 510006, China.

Background: As proven to reflect the work state of heart and physiological situation objectively, electrocardiogram (ECG) is widely used in the assessment of human health, especially the diagnosis of heart disease. The accuracy and reliability of abnormal ECG (AECG) decision depend to a large extent on the feature extraction. However, it is often uneasy or even impossible to obtain accurate features, as the detection process of ECG is easily disturbed by the external environment. Read More

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Comparison of surfactant mass transfer with drop formation times from dynamic interfacial tension measurements in microchannels.

J Colloid Interface Sci 2021 Jul 16;605:204-213. Epub 2021 Jul 16.

ThAMeS Multiphase, Department of Chemical Engineering, University College London, Torrington Place, London, WC1E 7JE, UK. Electronic address:

Dynamic interfacial tension was studied experimentally during drop formation in a flow-focusing microchannel. A low viscosity silicone oil (4.6 mPa s) was the continuous phase and a mixture of 48% w/w water and 52% w/w glycerol was the dispersed phase. Read More

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SARS-CoV-2 Antibodies and Associated Factors at Different Hospitalization Time Points in 192 COVID-19 Cases.

J Appl Lab Med 2021 Jul 30. Epub 2021 Jul 30.

Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.

Background: We launched a retrospective analysis of SARS-CoV-2 antibodies in 192 patients with COVID-19, aiming to depict the kinetic profile of SARS-CoV-2 antibodies and explore the factors related to SARS-CoV-2 antibody expression.

Methods: Data on 192 confirmed patients with COVID-19 between January and February 2020 was collected from the designated hospital that received patients with COVID-19 in Guangzhou, China. Moreover, a cohort of 130 suspected patients with COVID-19 and 209 healthy people were also enrolled in this study. Read More

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Error-free PAM-4 transmission by a high-speed plastic optical fiber without forward error correction.

Opt Lett 2021 Aug;46(15):3709-3712

This Letter reports, to the best of our knowledge, the first study in which error-free four-level pulse-amplitude modulation (PAM-4) transmission has been achieved using a graded-index plastic optical fiber (GI POF) without the use of forward error correction (FEC) techniques, at a high data rate (>50/), for short-reach applications (10 m). The GI POF that is developed has the characteristic microscopic heterogeneities in the fiber core material, which provide distinct mode coupling and significantly stabilize PAM-4 data transmission. The results of the study in this Letter indicate that the GI POF achieves highly stable PAM-4 transmission without the need for the current FEC techniques, which seriously increase the communication delay and power consumption of the transmission systems. Read More

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Insights into enhanced removal of 1,2-dichloroethane by amorphous boron-enhanced Fenton system: Performances and mechanisms.

J Hazard Mater 2021 Jul 9;420:126589. Epub 2021 Jul 9.

State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, East China University of Science and Technology, Shanghai 200237, China. Electronic address:

In this study, amorphous boron was employed as a reductant in traditional Fenton system for the first time to accelerate the regeneration of Fe(II). The degradation of 1,2-dichloroethane (DCA) was only 40.0% in Fenton system, while in the presence of amorphous boron, it could reach to 93. Read More

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The influence of biofilm maturation on fluoride's anticaries efficacy.

Clin Oral Investig 2021 Jul 30. Epub 2021 Jul 30.

Department of Cariology, Operative Dentistry and Dental Public Health, School of Dentistry, Indiana University, 415 Lansing Street, Indianapolis, IN, 46202-2876, USA.

Objectives: (1) To explore the influence of biofilm maturation and timing of exposure on fluoride anticaries efficacy and (2) to explore biofilm recovery post-treatment.

Methods: Bovine enamel specimens were utilized in a pH cycling model (28 subgroups [n = 18]). Each subgroup received different treatments [exposure]: sodium fluoride [NaF]; stannous fluoride [SnF]; amine fluoride [AmF]; and de-ionized water [DIW], at a specific period: early: days 1-4; middle: days 3-6; and late: days 7-10. Read More

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Migratory pattern of the coronavirus disease 2019 and high fatality rates among kidney transplant recipients: report from the Brazilian Multicenter Cohort Study.

J Bras Nefrol 2021 Jul 28. Epub 2021 Jul 28.

Universidade Federal de São Paulo, Hospital do Rim, São Paulo, SP, Brasil.

Introduction: The unprecedented coronavirus disease 2019 (COVID-19) pandemic has affected kidney transplant (KT) recipients, with worldwide fatality rates around 25%. Considering the well-known Brazilian socio-demographic disparities, this report describes for the first time the main outcomes of COVID-19 in KT recipients according to Brazilian geographic regions.

Methods: This multicenter national retrospective analysis included data from KT recipients with confirmed COVID-19 between March and November 2020. Read More

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Phytoremediation potential of forage mulberry ( Roxb.) for cadmium contaminated paddy soils.

Int J Phytoremediation 2021 Jul 30:1-7. Epub 2021 Jul 30.

The Sericultural Research Institute of Hunan Province, Changsha, China.

Mulberry is an important material to utilize the Cd polluted farmland in China and planting forage mulberry is a new development direction. This study aimed to investigate the changes of annual biomass and Cd content in shoot of Guisangyou 62, Guisangyou 12 and Yuesang 11 in field XT-C1, XT-X1 and ZZ-M1 under the pressure of Cd in 3 years. The Cd extraction ability of forage mulberry was analyzed, and the safety of forage mulberry was also discussed. Read More

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"I was not able to keep myself away from tending to her immediate needs": Primary Care Physicians' Perspectives of Serious Illness Conversations at Community Health Centers.

J Gen Intern Med 2021 Jul 29. Epub 2021 Jul 29.

Department of Family and Social Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.

Purpose: Seriously ill patients in low-income and minority populations have lower rates of advance care planning. Initiatives that promote serious illness (SI) conversations in community health centers (CHCs) can reach broad, diverse patient populations. This qualitative study explored the experiences of primary care physicians in conducting SI conversations at CHCs in order to understand challenges and needs in this setting. Read More

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Pulsed Electromagnetic Field Affects the Development of Postmenopausal Osteoporotic Women with Vertebral Fractures.

Biomed Res Int 2021 16;2021:4650057. Epub 2021 Jul 16.

Department of Orthopedics, Qinghai Provincial People's Hospital, Qinhai, China.

Background: Postoperative pain, dysfunction, and significant bone loss may occur after vertebral fractures, which will lead to the occurrence of refractures and shorten the survival time, so postoperative rehabilitation is very important. Pulsed electromagnetic field therapy is noninvasive, pain-relieving, and beneficial to reduce bone loss and is an important treatment for patients to recover after surgery. Therefore, this study analyzed the effect of postmenopausal women's vertebral fracture rehabilitation after pulsed electromagnetic field treatment. Read More

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Potassium Iodide Tablets Instead of a Saturated Solution Preoperatively for Reaching Euthyroidism Quickly in Refractory Graves' Disease.

Cureus 2021 Jun 23;13(6):e15854. Epub 2021 Jun 23.

Polyclinic for Endocrinology, Diabetes and Preventive Medicine, University Hospital of Cologne, Cologne, DEU.

The optional use of a saturated solution of potassium iodide in the immediate preoperative period to reach euthyroidism is included both in the American Thyroid Association (ATA) and in the European Thyroid Association (ETA) guidelines for the treatment of Graves' disease (GD). The recent literature though, shows that it does not translate to more clinically meaningful differences in surgical outcome. In our experience, potassium iodide should not be seen as a means for reducing operative time or complications; it is an effective way for reaching euthyroidism quickly. Read More

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Clinical Characteristics, Treatment and Evolution of Splenic and Nodal Marginal Zone Lymphomas-Retrospective and Multicentric Analysis of Portuguese Centers.

Clin Lymphoma Myeloma Leuk 2021 Jun 24. Epub 2021 Jun 24.

Centro Hospitalar e Universitário do Porto, Hospital Geral de Santo António, Porto, Portugal.

Introduction: Treatment of Splenic (SMZL) and Nodal (NMZL) Marginal Zone Lymphoma is not consensual. Histologic transformation (HT) to aggressive lymphoma is a poorly understood event, with an unfavorable outcome.

Objectives: Describe the clinical characteristics, treatment, outcomes and incidence of HT. Read More

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COVEPIC (Cognitive and spOrt Virtual EPIC training) investigating the effects of home-based physical exercise and cognitive training on cognitive and physical functions in community-dwelling older adults: study protocol of a randomized single-blinded clinical trial.

Trials 2021 Jul 29;22(1):505. Epub 2021 Jul 29.

Research center and Centre ÉPIC, Montreal Heart Institute, Université de Montréal, Montréal, Québec, H1T 1 N6, Canada.

Background: In the context of the COVID-19 pandemic, lockdown and social distancing measures are applied to prevent the spread of the virus. It is well known that confinement and social isolation can have a negative impact on physical and mental health, including cognition. Physical activity and cognitive training can help enhance older adults' cognitive and physical health and prevent the negative collateral impacts of social isolation and physical inactivity. Read More

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A stability perspective of bio-inspired UAVs performing dynamic soaring optimally.

Bioinspir Biomim 2021 Jul 29. Epub 2021 Jul 29.

Air University, Aerospace & Aviation Campus, Air University, Aerospace & Aviation Campus, Kamra, 44200, PAKISTAN.

Dynamic soaring phenomenon, exhibited by soaring birds, has long been a biological inspiration for the aerospace and control engineering communities. If this fascinating phenomenon, which allows soaring birds to perform almost un-powered flights using wind shear, can be mimicked by Unmanned-Aerial-Vehicles (UAVs), then UAVs performance have a substantial potential to enhance technologically and economically as well. Even though there have been considerable amount of research covering the modeling, optimization, control and simulation aspects of different UAVs performing dynamic soaring, there is little to non conclusive work analyzing the stability of such UAVs about the soaring orbits. Read More

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Enhanced depletion of antibiotics and accelerated estabilization of dissolved organic matter by hydrothermal pretreatment during composting of oxytetracycline fermentation residue.

Bioresour Technol 2021 Jul 22;339:125618. Epub 2021 Jul 22.

College of Environmental Science and Engineering, Tongji University, Shanghai 200092, PR China.

In this study, the feasibility of employing hydrothermal pretreatment (HTPT) to improve the composting of oxytetracycline fermentation residue (OFR) was evaluated by investigating the depletion of oxytetracycline (OTC) and evolution of dissolved organic matter (DOM). HTPT drastically declined the final content of OTC and its main transformation intermediates in OFR compost from 89.96 to 2. Read More

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Novel DyO/ZnO-Au ternary nanocomposites: Green synthesis using pomegranate fruit extract, characterization and their photocatalytic and antibacterial properties.

Bioorg Chem 2021 Jul 23;115:105204. Epub 2021 Jul 23.

Department of Chemistry, Mahabad Branch, Islamic Azad University, Mahabad, Iran. Electronic address:

In this study for the first time, high efficient, eco-friendly and novel DyO/ZnO-Au ternary nanocomposites (Dy/ZnO-AuNCs) were prepared in presence of pomegranate fruit (PF) extract as capping and reducing agents (Dy/[email protected]). The influence of various parameters such as basic agents, reducing agents, sonication power, and sonication time were performed to reach the optimum condition. The formation of the products was characterized by FT-IR, HRTEM, XRD, FE-SEM, TEM, EDX and DRS techniques. Read More

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Hemodynamic impact of increasing time between fentanyl and propofol administration during anesthesia induction: a randomised, clinical trial.

Braz J Anesthesiol 2021 Jul 26. Epub 2021 Jul 26.

Hospital Central de la Defensa Gómez Ulla-IMIDEF, Critical Care and Pain Unit, Department of Anesthesia, Madrid, Spain.

Background And Objective: Anesthesia induction can produce severe propofol dose-dependent hypotension. Fentanyl coadministration reduces the catecholaminergic response to orotracheal intubation allowing propofol dose reduction. The aim of this study is to determine whether the hemodynamic response is improved by increasing the time between fentanyl and propofol administration and reducing the dose of the latter without increasing the time to achieve optimal hypnosis. Read More

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Preparation of low molecular chitosan by microwave-induced plasma desorption/ionization technology.

Int J Biol Macromol 2021 Jul 26. Epub 2021 Jul 26.

Research Center of Analytical Instrumentation, Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry & Materials Science, Northwest University, Xi'an, Shaanxi 710069, China. Electronic address:

Compared with high molecular weight chitosan (HMWC), low molecular weight chitosan (LMWC) has better solubility and biological activity. However, there is no quick and environmentally friendly to prepare low molecular chitosan. In this study, microwave induced plasma desorption/ionization (MIPDI) was used for the first time to prepare LMWC through the degradation processes of HMWC. Read More

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Food insecurity and mental health of women during COVID-19: Evidence from a developing country.

PLoS One 2021 29;16(7):e0255392. Epub 2021 Jul 29.

Centre for Development Economics and Sustainability, Department of Economics, Monash University, Melbourne, Australia.

Background: This study examines the association between food insecurity and mental health of women during the COVID-19 pandemic in a resource poor setting.

Materials And Methods: Data were collected at two time-points (wave 1 and 2) from 2402 women, one per household, participating in a larger study during extended COVID-19 lockdown in the rural areas of the southwest region of Bangladesh. The primary outcome of the analyses is the association between food insecurity, measured using the Food Insecurity Experience Scale (FIES), and stress level, measured using the Perceived Stress Scale (PSS), for women during the lockdown. Read More

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Topological network based drug repurposing for coronavirus 2019.

PLoS One 2021 29;16(7):e0255270. Epub 2021 Jul 29.

Department of Electrical Engineering and Computer Science, KTH Royal Institute of Technology, Stockholm, Sweden.

The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has become the current health concern and threat to the entire world. Thus, the world needs the fast recognition of appropriate drugs to restrict the spread of this disease. The global effort started to identify the best drug compounds to treat COVID-19, but going through a series of clinical trials and our lack of information about the details of the virus's performance has slowed down the time to reach this goal. Read More

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Role-Based Framing of Older Adults Linked to Decreased Ageism Over 210 Years: Evidence From a 600-Million-Word Historical Corpus.

Gerontologist 2021 Jul 29. Epub 2021 Jul 29.

Lee Kuan Yew School of Public Policy, National University of Singapore, Singapore.

Background And Objectives: Older adults are exhibiting greater diversity in their aging trajectories. This has led to movements by the World Health Organization and AARP to reframe aging. We compare role-based framing and age-based framing of older adults over 210 years-a time span beyond the reach of traditional methods-and elucidate their respective sentiments and narratives. Read More

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Efficient energy transfer from Bi to Mn in CaZnOS for WLED application.

Dalton Trans 2021 Jul 29. Epub 2021 Jul 29.

School of Materials Science and Engineering, Shanghai University, Shanghai, 200072, P.R. China.

A series of Bi3+ and Mn2+ co-doped CaZnOS phosphors with a tunable emission color have been synthesized by a high temperature solid-state reaction method. Their crystal structure, spectroscopic properties, energy transfer and thermal quenching have been investigated systematically. An intense blue-green emission band at 485 nm and a red emission band at 616 nm were observed at an excitation wavelength of 375 nm, owing to the 3P1,0 → 1S0 transition of Bi3+ and the 4T1(4G) → 6A1(6S) transition of Mn2+, respectively. Read More

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Multi-step ahead thermal warning network for energy storage system based on the core temperature detection.

Sci Rep 2021 Jul 28;11(1):15332. Epub 2021 Jul 28.

Key Laboratory of Smart Grid of Ministry of Education, Tianjin University, Tianjin, 300072, China.

The energy storage system is an important part of the energy system. Lithium-ion batteries have been widely used in energy storage systems because of their high energy density and long life. However, the temperature is still the key factor hindering the further development of lithium-ion battery energy storage systems. Read More

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Antidepressant and anti-amnesic effects of the aqueous lyophilisate of the leaves of Leptadenia arborea on an animal model of cognitive deficit associated depression.

Biomed Pharmacother 2020 Oct 17;130:110603. Epub 2020 Aug 17.

Department of Biological Sciences, Faculty of Science, University of Maroua, P.O. Box 46, Maroua, Cameroon.

Leptadenia arborea (Asclepiadaceae) is a plant used in traditional medicine to treat syphilis, migraine, and mental illnesses. The aim of our study was to investigate possible antidepressant and anti-amnesic effects of the aqueous lyophilisate of the leaves of Leptadenia arborea in an animal model of cognitive deficit associated depression. Swiss albino adult mice of both sexes were used for this study. Read More

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October 2020

Task Oriented Training Activities Post Stroke Will Produce Measurable Alterations in Brain Plasticity Concurrent with Skill Improvement.

Top Stroke Rehabil 2021 Jul 28:1-14. Epub 2021 Jul 28.

Department of Exercise and Nutrition Science, George Washington University, Washington, DC, USA.

Background: Task-oriented training with upper extremity (UE) skilled movements has been established as a method to regain function post stroke. Although improved UE function has been shown after this type of therapy, there is minimal evidence that brain plasticity is associated with this training. The accelerated skill acquisition program (ASAP) is an example of an approach for promoting UE function using targeting movements. Read More

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Gaze control during reaching is flexibly modulated to optimize task outcome.

J Neurophysiol 2021 07 28. Epub 2021 Jul 28.

The Brain and Mind Institute, University of Western Ontario, London, Ontario, Canada.

When reaching for an object with the hand, the gaze is usually directed at the target. In a laboratory setting, fixation is strongly maintained at the reach target until the reaching is completed, a phenomenon known as "gaze-anchoring". While conventional accounts of such tight eye-hand coordination have often emphasized the internal synergetic linkage between both motor systems, more recent optimal control theories regard motor coordination as the adaptive solution to task requirements. Read More

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