J ECT 2021 Apr 26. Epub 2021 Apr 26.
From the Department for Affective Disorders Department of Clinical Epidemiology, Aarhus University Hospital Psychiatric Centre Amager, Mental Health Services Capital Region of Denmark, Aarhus Centre for Neuropsychiatric Depression Research, Mental Health Centre Glostrup, Glostrup, Denmark.
Objectives: Severe depression is associated with an increased risk of developing dementia, however, whether treatment with electroconvulsive therapy (ECT) modify this risk remains unknown.
Methods: In this matched cohort study, 1089 consecutive in-patients with affective disorders, receiving ECT during the period 1982 to 2000, were matched with 3011 in-patients with affective disorders not treated with ECT (non-ECT), and 108,867 individuals randomly selected from the background population. The comparison cohorts were matched on sex, age, and the non-ECT cohort was further matched according to diagnoses and admission period and hospital. Read More