157,584 results match your criteria time literature

Medullary thyroid carcinoma (MTC): unusual metastatic sites.

Endocrinol Diabetes Metab Case Rep 2021 Sep 1;2021. Epub 2021 Sep 1.

Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Summary: Medullary thyroid carcinoma (MTC) has a varying clinical course; distant metastases are frequently present even at diagnosis. We present two MTC cases with unusual metastatic sites. Two female patients are presented with slow progressive MTC. Read More

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September 2021

Between a rock and a hard place: Ethics, nurses' safety, and the right to protest during the COVID-19 pandemic.

Int Nurs Rev 2021 Sep;68(3):270-278

Department of Nursing, Walter Sisulu University, Mthatha, South Africa.

Aim: In this paper, we critically discuss the ethics of nurses' choice to strike during the COVID-19 pandemic, considering legal and ethical arguments, overlaying the Ubuntu philosophy, an African ethic.

Background: The recent unprecedented coronavirus disease pandemic and the increased reports on the absence of personal protective equipment in South Africa places many health workers' lives at risk. Nurses spend most of their time with patients, which exposes them to fatal risks as they work in unsafe environments. Read More

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September 2021

Rewinding the molecular clock in the genus Carabus (Coleoptera: Carabidae) in light of fossil evidence and the Gondwana split: A reanalysis.

PLoS One 2021 22;16(9):e0256679. Epub 2021 Sep 22.

Institute of Biosciences, General and Systematic Zoology, University of Rostock, Rostock, Germany.

Molecular clocks have become powerful tools given increasing sequencing and fossil resources. However, calibration analyses outcomes depend on the choice of priors. Here, we revisited the seminal dating study published by Andújar and coworkers of the genus Carabus proposing that prior choices need re-evaluation. Read More

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September 2021

Real-World Treatment Patterns and Healthcare Costs in Patients with Psoriatic Arthritis Treated with Ixekizumab: A Retrospective Study.

ACR Open Rheumatol 2021 Sep 22. Epub 2021 Sep 22.

Hospital of the University of Pennsylvania, Philadelphia.

Objective: To describe adherence, persistence, discontinuation, restarting, switching, dosing, and health care costs among patients with psoriatic arthritis (PsA) treated with ixekizumab (IXE).

Methods: MarketScan administrative claims databases were used to select adults (≥18 years) initiating IXE between January 1, 2016, and June 30, 2019, for this retrospective study (earliest IXE claim = index). Eligible patients had one or more PsA diagnoses during the 12 months preceding the index and had 12 months of follow-up time after the index. Read More

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September 2021

Does the wearing of masks change voice and speech parameters?

Eur Arch Otorhinolaryngol 2021 Sep 22. Epub 2021 Sep 22.

Voice and Swallowing Clinic, Department of Otolaryngology Head and Neck Surgery, Cliniques Universitaires Saint-Luc, 10 avenue Hippocrate, 1200, Brussels, Belgium.

Purpose: The authors aim to review available reports on the potential effects of masks on voice and speech parameters.

Methods: A literature search was conducted using MEDLINE and Google Scholar databases through July 2021. Several targeted populations, mask scenarios and methodologies were approached. Read More

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September 2021

Cost-effectiveness analysis comparing intensity-modulated radiotherapy with conformational radiotherapy (3D-RT) for prostate cancer in the brazilian health system.

Rev Assoc Med Bras (1992) 2021 Jun;67(5):724-730

Instituto de Biociência da Universidade do Estado de São Paulo - Botucatu (SP), Brazil.

Objective: The intensity-modulated radiotherapy (IMRT) has been established as the standard external-beam radiation technique to treat prostate cancer in several countries. In Brazil, the public health system and the National Health Agency do not reimburse its utilization. This study compared the cost-effectiveness of IMRT and tridimensional radiotherapy (3D-RT) from a payer's perspective. Read More

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Can Wearable Sweat Lactate Sensors Contribute to Sports Physiology?

ACS Sens 2021 Sep 22. Epub 2021 Sep 22.

Department of Chemistry, KTH Royal Institute of Technology, Teknikringen 30, SE-100 44 Stockholm, Sweden.

The rise of wearable sensors to measure lactate content in human sweat during sports activities has attracted the attention of physiologists given the potential of these "analytical tools" to provide real-time information. Beyond the assessment of the sensing technology , which, in fact, has not rigorously been validated yet in controlled conditions, there are many open questions about the true usefulness of such wearable sensors in real scenarios. On the one hand, the evidence for the origin of sweat lactate (e. Read More

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September 2021

analysis of n-acetylcysteine (NAC) interference with the international normalized ratio (INR).

Clin Toxicol (Phila) 2021 Sep 22:1-4. Epub 2021 Sep 22.

Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, MD, USA.

Background: Previous literature suggests a laboratory interference of n-acetylcysteine (NAC) with prothrombin time (PT) and the international normalized ratio (INR). Early publications focused on this interaction in the setting of an acetaminophen overdose and evaluated the INR of patients receiving intravenous NAC. However, there is limited literature describing the concentration-effect relationship of NAC to INR measurement in the absence of acetaminophen-induced hepatotoxicity at therapeutic NAC concentrations. Read More

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September 2021

Arthroscopic Subtalar Joint Arthrodesis: Topical Review.

Foot Ankle Int 2021 Sep 22:10711007211035397. Epub 2021 Sep 22.

Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, Surrey, United Kingdom.

Background: Advances in foot and ankle arthroscopy over the last 2 decades have allowed for subtalar joint arthrodesis to be performed arthroscopically. The potential advantages of the arthroscopic technique include higher fusion rates, lower complications, reduced perioperative morbidity, and accelerated rehabilitation. Arthroscopic arthrodesis may, however, not be appropriate in the setting of complex deformity correction or the need for other open procedures. Read More

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September 2021

Early Outcomes of Scapholunate Injuries With Concomitant Distal Radius Fractures.

Hand (N Y) 2021 Sep 9;16(5):650-656. Epub 2019 Dec 9.

Mayo Clinic, Rochester MN, USA.

There is limited literature regarding the treatment of concomitant scapholunate ligament (SL) injuries in acute distal radius fractures (DRFs). We hypothesized that surgical treatment of SL injuries in adult patients with DRFs leads to improved functional outcomes. A retrospective review was made of 42 adult patients who underwent surgical treatment of a DRF with a SL injury between 2005 and 2013. Read More

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September 2021

[Project to Improve Satisfaction in the Conscription Physical Examinations Service].

Hu Li Za Zhi 2021 Oct;68(5):65-73

MSN, RN, Supervisor, Department of Nursing, National Taiwan University Hospital, Hsin-Chu Branch, Taiwan, ROC.

Background & Problems: In response to a decrease in satisfaction to 69.3%, we resolved to optimize the process of conducting conscription physical examinations. After an investigatory panel conducted an analysis, the following problems were identified. Read More

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October 2021

[Applying Virtual Reality Assisted Critical Thinking Training Programs Among Nurse Practitioners].

Shih-Chun Lin

Hu Li Za Zhi 2021 Oct;68(5):18-23

MS, RN, NP, Supervisor, Department of Nursing, Buddhist Dalin Tzu Chi Hospital, Taiwan, ROC.

The three-dimensional virtual world generated in virtual reality (VR) environments involves vision, hearing, touch, and potentially other user senses. VR environments are designed to closely simulate real situations/scenarios, allowing users to observe and engage in experiences free of time and space restrictions. Virtual patients are an extension of virtual reality. Read More

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October 2021

Use of Thromboelastography in the Evaluation and Management of Patients With Traumatic Brain Injury: A Systematic Review and Meta-Analysis.

Crit Care Explor 2021 Sep 14;3(9):e0526. Epub 2021 Sep 14.

Department of Surgery, Division of Traumatology, Surgical Critical Care & Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

Traumatic brain injury is associated with coagulopathy that increases mortality risk. Viscoelastic hemostatic assays such as thromboelastography (Haemonetics SA, Signy, Switzerland) provide rapid coagulopathy assessment and may be particularly useful for goal-directed treatment of traumatic brain injury patients. We conducted a systematic review to assess thromboelastography in the evaluation and management of coagulopathy in traumatic brain injury patients. Read More

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September 2021

A narrative review of fluorescence imaging in robotic-assisted surgery.

Laparosc Surg 2021 Jul 25;5. Epub 2021 Jul 25.

Department of Research, Intuitive Surgical, Inc., Sunnyvale, CA, USA.

Objective: In this review, we provide examples of applications of fluorescence imaging in urologic, gynecologic, general, and endocrine surgeries.

Background: While robotic-assisted surgery has helped increase the availability of minimally invasive procedures across surgical specialties, there remains an opportunity to reduce adverse events associated with open, laparoscopic, and robotic-assisted methods. In 2011, fluorescence imaging was introduced as an option to the da Vinci Surgical System, and has been standard equipment since 2014. Read More

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A mobile app for delirium screening.

JAMIA Open 2021 Apr 20;4(2):ooab027. Epub 2021 May 20.

Division of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

Objective: The objective of this study is to describe the algorithm and technical implementation of a mobile app that uses adaptive testing to assess an efficient mobile app for the diagnosis of delirium.

Materials And Methods: The app was used as part of a NIH-funded project to assess the feasibility, effectiveness, administration time, and costs of the 2-step delirium identification protocol when performed by physicians and nurses, and certified nursing assistants (CNA). The cohort included 535 hospitalized patients aged 79. Read More

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Discrepancies between Conference Abstracts and Published Manuscripts in Plastic Surgery Studies: A Retrospective Review.

Plast Reconstr Surg Glob Open 2021 Sep 17;9(9):e3828. Epub 2021 Sep 17.

Department of Plastic and Oral Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Mass.

Background: Inconsistency in results and outcomes between presented abstracts and corresponding published articles can negatively affect clinical education and care. The objective of this study was to describe the frequency of clinically meaningful change in results and outcomes between abstracts presented at the American Association of Plastic Surgeons annual conference and the corresponding published articles, and to determine risk factors associated with discrepancies.

Methods: All abstracts delivered as oral presentations at the American Association of Plastic Surgeons conference (2006-2016) were reviewed. Read More

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September 2021

K-wire Made Easy by Premarking Wire Trajectory on the Skin in Management of Finger Fractures.

Plast Reconstr Surg Glob Open 2021 Sep 17;9(9):e3797. Epub 2021 Sep 17.

Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia.

Background: Hand injury in general and fractures in particular are among the most common complaints of hand trauma patients presenting to our emergency department. Depending on fracture types, geometry, locations, and stability, treatment options may vary from close reduction and splinting to close reduction and K-wire fixation, and finally, to open reduction and internal fixation. The aim of the study was to prove that premarking of K-wire trajectory helps reduce procedure and fluoroscopy time, as well as the number of wire-insertion attempts, and minimize bone and soft tissue injury in the management of phalangeal finger fractures. Read More

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September 2021

Advancing urban ethnopharmacology: a modern concept of sustainability, conservation and cross-cultural adaptations of medicinal plant lore in the urban environment.

Conserv Physiol 2021 16;9(1):coab073. Epub 2021 Sep 16.

Ethnopharmacology and Natural Product Research Laboratory, Department of Life Sciences, Presidency University, 86/1 College Street, Kolkata, 700073, West Bengal, India.

The discipline 'urban ethnopharmacology' emerged as a collection of traditional knowledge, ancient civilizations, history and folklore being circulated since generations, usage of botanical products, palaeobotany and agronomy. Non-traditional botanical knowledge increases the availability of healthcare and other essential products to the underprivileged masses. Intercultural medicine essentially involves 'practices in healthcare that bridge indigenous medicine and western medicine, where both are considered as complementary'. Read More

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September 2021

Bird's-Eye View of COVID-19 Knowledge, Attitude and Practice Among Emergency Physicians in the Kingdom of Bahrain: A Cross-Sectional Study.

Open Access Emerg Med 2021 14;13:415-423. Epub 2021 Sep 14.

Emergency Department, Bahrain Defence Force Hospital, West Riffa, Bahrain.

Background: Coronavirus 2019 (COVID-19) has exemplified the crucial role played by emergency physicians on the frontlines, by triaging, quarantining and treating myriad patients in time. Despite this, there exists a dearth of literature comprehensively assessing the knowledge and awareness of these health-care workers on the disease in the Kingdom of Bahrain. This study was designed to evaluate the knowledge, attitude, and practice (KAP) of emergency physicians in the Kingdom of Bahrain towards COVID-19. Read More

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September 2021

Epidemiology of Sepsis-Associated Acute Kidney Injury in Beijing, China: A Descriptive Analysis.

Int J Gen Med 2021 14;14:5631-5649. Epub 2021 Sep 14.

Department of Intensive Care Unit, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.

Background: Sepsis is the most common contributing factor towards development of acute kidney injury (AKI), which is strongly associated to poor prognostic outcomes. There are numerous epidemiological studies about sepsis-associated acute kidney injury (S-AKI), however current literature is limited with the majority of studies being conducted only in the intensive care unit (ICU) setting. The aim of this study was to assess the epidemiology of S-AKI in all hospitalized in-patients. Read More

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September 2021

Prediction of coating thickness for polyelectrolyte multilayers via machine learning.

Sci Rep 2021 Sep 21;11(1):18702. Epub 2021 Sep 21.

SPARTHA Medical, 67100, Strasbourg, France.

Layer-by-layer (LbL) deposition method of polyelectrolytes is a versatile way of developing functional nanoscale coatings. Even though the mechanisms of LbL film development are well-established, currently there are no predictive models that can link film components with their final properties. The current health crisis has shown the importance of accelerated development of biomedical solutions such as antiviral coatings, and the implementation of machine learning methodologies for coating development can enable achieving this. Read More

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September 2021

Treatment of acute aneurysmal subarachnoid haemorrhage with primary flow diversion: 5-year single-centre experience.

Clin Radiol 2021 Sep 18. Epub 2021 Sep 18.

Neuroradiology Department, Royal Victoria Hospital, Belfast, UK.

Aim: To evaluate the safety and efficacy of treatment of patients presenting with acute aneurysmal subarachnoid haemorrhage (SAH) with primary flow-diverting stents (FDS; with or without adjuncts), with comparison to the published literature.

Materials And Methods: A retrospective single-centre review was undertaken of prospectively obtained data on patients treated for SAH over a 60-month period. Of 354 patients treated for SAH during that time period, 24 patients with a total of 25 aneurysms were identified. Read More

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September 2021

Treatment of bipolar disorders in older adults: a review.

Ann Gen Psychiatry 2021 Sep 21;20(1):45. Epub 2021 Sep 21.

Bereich Forschung & Wissenschaft, LWL-Klinik, Marsbruchstr. 179, 44287, Dortmund, Germany.

Background: Old age bipolar disorder has been an orphan of psychiatric research for a long time despite the fact that bipolar disorder (BD)-I and II together may affect 0.5-1.0% of the elderly. Read More

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September 2021

An improved method for the effect estimation of the intermediate event on the outcome based on the susceptible pre-identification.

BMC Med Res Methodol 2021 Sep 21;21(1):192. Epub 2021 Sep 21.

Department of Health Statistics, Faculty of Preventive Medicine, Air Force Medical University, No.169 Changle West Road, Xi'an, 710032, Shaanxi, China.

Background: In follow-up studies, the occurrence of the intermediate event may influence the risk of the outcome of interest. Existing methods estimate the effect of the intermediate event by including a time-varying covariate in the outcome model. However, the insusceptible fraction to the intermediate event in the study population has not been considered in the literature, leading to effect estimation bias due to the inaccurate dataset. Read More

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September 2021

The high potency of polymeric nanoparticles in the drug delivery system for hypertension treatment; A systematic review.

Curr Hypertens Rev 2021 Sep 21. Epub 2021 Sep 21.

Cardiovascular Research Center, Lorestan University of Medical Sciences, Khorramabad. Iran.

Background: Polymeric nanomaterials with size ranging from 10 to 1000 nm are one of the most widely used types of nanoparticles with ideal properties in the drug delivery systems. Here, we decided to systematically review the antihypertensive effects of polymeric nanomaterials in vitro, in vivo, and clinical trials.

Methods: The present review was conducted based on the 06- PRISMA guideline; whereas five English databases, including Scopus, PubMed, Web of Science, EMBASE, and Google Scholar without time limitation were used for searching the publications related to antihypertensive effects of natural and synthetic polymeric nanoparticles. Read More

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September 2021

3D MRI in Musculoskeletal Oncology.

Semin Musculoskelet Radiol 2021 Jun 21;25(3):418-424. Epub 2021 Sep 21.

The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Advances in magnetic resonance imaging (MRI) technology now enable the feasible three-dimensional (3D) acquisition of images. With respect to the imaging of musculoskeletal (MSK) tumors, literature is beginning to accumulate on the use of 3D MRI acquisition for tumor detection and characterization. The benefits of 3D MRI, including general advantages, such as decreased acquisition time, isotropic resolution, and increased image quality, are not only inherently useful for tumor imaging, but they also contribute to the feasibility of more specialized tumor-imaging techniques, such as whole-body MRI, and are reviewed here. Read More

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Depth of thermal dispersion of monopolar radiofrequency heating in the vaginal wall.

Biomed Phys Eng Express 2021 Sep 21. Epub 2021 Sep 21.

Center for Devices and Radiological Health, Office of Science and Engineering Laboratories, Division of Applied Mechanics, US Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Maryland, 20993, UNITED STATES.

The use of energy-based devices to treat genitourinary syndrome of menopause, termed vaginal thermotherapy (VTT), has gained significant interest in recent years. Among the primary safety concerns of this relatively new procedure is the possibility of unintentionally heating tissues adjacent to the vaginal wall, i.e. Read More

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September 2021

When in America, do as the Americans? The evolution of health behaviors and outcomes across immigrant cohorts.

Econ Hum Biol 2021 Sep 14;43:101063. Epub 2021 Sep 14.

Department of Economics, Illinois Wesleyan University, 1402 Park Street, SFH 320, Bloomington, IL 61702, USA. Electronic address:

This study seeks to understand US immigrants' health-related behaviors and outcomes across arrival cohorts. We simultaneously examine risky consumption choices (smoking and drinking) and physical health conditions (asthma, diabetes, vision problems, and coronary heart diseases) using data from the National Health Interview Surveys (1989-2018). We incorporate cohort fixed-effects and the interactions between cohort effects and years since immigration into our empirical framework to capture the dynamics of immigrant health over time. Read More

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September 2021

Anti-interleukin-5 in the Management of Eosinophilic Asthma: A Review of Effectiveness, Safety, and Budgetary Impact From the Perspective of the Brazilian Health System.

Value Health Reg Issues 2021 Sep 18;26:169-181. Epub 2021 Sep 18.

Universidade Federal de Mato Grosso - UFMT/Universidade de Várzea Grande-MT, Cuiabá-MT, Brasil.

Objectives: To evaluate the efficacy and safety of anti-interleukin-5 class therapy agents in the treatment of eosinophilic asthma and the financial impact of these drugs on the Brazilian and Mato Grosso public health systems.

Methods: The literature review in important databases was guided by a structured research question including patient or population, intervention, comparator, outcome and type of study. The retrieved studies went through a screening, selection, data extraction, and methodological quality assessment process. Read More

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September 2021

Key particle properties of shells for cadmium chemisorption.

Chemosphere 2021 Sep 16;287(Pt 3):132257. Epub 2021 Sep 16.

Department of Applied Sciences, Muroran Institute of Technology, 050-8585, Hokkaido, Japan. Electronic address:

Previous studies on cadmium adsorption of calcium carbonate have found that polymorph, and, crystallinity are influential factors for adsorbing cadmium ions. The predominant factor for cadmium adsorption has yet to be elucidated because these factors are linked. To overcome this, here each factor is investigated separately. Read More

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September 2021