12,641 results match your criteria thyroid scan

It's All Due to the Thyroid: Lessons Learnt From a Patient's Perspective.

Cureus 2021 Jun 23;13(6):e15876. Epub 2021 Jun 23.

Endocrinology, Wyoming Medical Center, Casper, USA.

Symptoms associated with thyroid pathology can mimic and overlap with a myriad of other diagnostic possibilities. Based on the patient's educational status, underlying fear, anxiety, online medical search, the patient can erroneously attribute various symptoms to thyroid pathology. We present a case of a 79-year-old female with a history of Hashimoto's hypothyroidism, meningioma, who erroneously attributed many of her symptoms to hypothyroidism despite having normal thyroid labs. Read More

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Should fluorodeoxyglucose positron emission tomography/computed tomography be the first-line imaging investigation for restaging the laryngeal carcinoma patients?

World J Nucl Med 2021 Apr-Jun;20(2):164-171. Epub 2021 Feb 12.

Department of Medical Oncology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India.

Posttreatment detection of residual/recurrence disease in the head and neck cancers is not an easy task. Treatment induces changes create difficulties in diagnosis on conventional imaging (computed tomography [CT], magnetic resonance imaging) as well as macroscopic inspection (direct laryngoscopy). Hence, we evaluate the diagnostic performance of contract-enhanced F-18 fluorodeoxyglucose positron emission tomography (FDG PET)/CT in restaging of laryngeal carcinoma Postchemotherapy-surgery and/or radiation therapy. Read More

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February 2021

Trends in the utilization of nuclear medicine technology in Jamaica: Audit of a private facility.

World J Nucl Med 2021 Apr-Jun;20(2):129-132. Epub 2020 Sep 14.

Department of Basic Medical Sciences, Faculty of Medical Sciences, University of the West Indies, Kingston, Jamaica.

This study sought to evaluate the types and frequencies of nuclear medicine studies that were carried out at a privately-run nuclear medicine facility in Kingston, Jamaica. Previous studies of this nature have not been done among this population, therefore the researchers sought to gather data which may prove to be useful for the growth of nuclear medicine practice in Jamaica. The study was a nonexperimental, retrospective study which involved an assessment of the records of all nuclear medicine patients who received a radiopharmaceutical during January 01, 2017, to December 31, 2018. Read More

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September 2020

Incidental Pituitary Adenoma on MIBI Parathyroid Imaging.

Clin Nucl Med 2021 Jul 26. Epub 2021 Jul 26.

From the Nuclear Medicine Unit/Radiology and Medical City, King Saud Medical City, Riyadh, Saudi Arabia.

Abstract: A 77-year-old man with a case of hyperthyroidism with high parathyroid hormone (41 pmol/L), low vitamin D, and normal thyroid-stimulating hormone. The SPECT/CT fused images confirmed the evidence of retrotracheal hyperdense mass approximately 1.0 cm of diameter below the lower pole of the right thyroid lobe with increased uptake, highly suggestive of typical parathyroid adenoma. Read More

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Primary Extra-Osseous Ewing Sarcoma of the Thyroid: A Case Report and Review of the Literature.

Head Neck Pathol 2021 Jul 26. Epub 2021 Jul 26.

Department of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland.

Extra-osseous Ewing sarcoma (ES) is a rare and aggressive malignant tumor found in a variety of organs. Primary ES of the thyroid is exceedingly rare and few cases have been documented to date. We describe the case of a 54-year old woman with a history of breast carcinoma in whom a unique hypermetabolic left thyroid nodule was identified during a follow-up PET-CT scan. Read More

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Metastatic Malignant Struma Ovarii and Graves' Disease: A Rare Occurrence.

AACE Clin Case Rep 2021 Jul-Aug;7(4):243-246. Epub 2021 Jan 6.

Tan Tock Seng Hospital, Department of Endocrinology, Novena, Singapore.

Objective: Malignant struma ovarii (SO) is a rare condition. Although there have been a few reported cases of malignant SO with coexisting Graves' disease (GD), the exact incidence of metastasis in these cases is not known. We report a rare case of metastatic malignant SO coexisting with GD. Read More

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January 2021

Concomitant Langerhans cell histiocytosis of cervical lymph nodes in adult patients with papillary thyroid carcinoma: A report of two cases and review of the literature.

Autops Case Rep 2021 12;11:e2021253. Epub 2021 Mar 12.

King Hussein Cancer Center, Department of Pathology and Laboratory Medicine, Amman, Jordan.

Objective: : Langerhans cell histiocytosis (LCH) is an uncommon entity of unknown etiology. It contains a wide range of clinical presentations. The discovery of oncogenic mutation in LCH has provided additional evidence that LCH is a neoplasm. Read More

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Two Cases of Atraumatic Laryngeal Fractures.

J Voice 2021 Jul 19. Epub 2021 Jul 19.

European Institute for ORL-HNS, Department of ENT-HNS, Sint-Augustine's, GZA Hospital, Antwerp, Belgium.

Introduction And Aim: Atraumatic laryngeal fractures are extremely rare and are most commonly provoked by sneezing or coughing. Only seven cases have been described in medical literature, and only one case described a fracture after swallowing. We present two cases of atraumatic laryngeal fracture after swallowing. Read More

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False-Positive 123I-Uptake Mimics Metastatic Lung Disease in a Patient With Interstitial Lung Disease Secondary to Scleroderma.

Clin Nucl Med 2021 Jul 20. Epub 2021 Jul 20.

From the Lewis Katz School of Medicine at Temple University Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Temple Health System, Lewis Katz School of Medicine, Philadelphia, PA.

Abstract: A 59-year-old woman with a history of papillary thyroid cancer status post total thyroidectomy and 131I ablation therapy presented with lower back pain and leg weakness. MRI of the lumbar spine revealed homogenously enhancing lesions at L1-L2 and L3-L4. Subsequent whole-body 123I-Na scan demonstrated significant 123I retention in the mid to distal esophagus, as well as diffuse uptake in basal segments of the lungs bilaterally. Read More

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Decision Making When Cancer Becomes Chronic: Needs Assessment for a Web-Based Medullary Thyroid Carcinoma Patient Decision Aid.

JMIR Form Res 2021 Jul 16;5(7):e27484. Epub 2021 Jul 16.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

Background: In cancers with a chronic phase, patients and family caregivers face difficult decisions such as whether to start a novel therapy, whether to enroll in a clinical trial, and when to stop treatment. These decisions are complex, require an understanding of uncertainty, and necessitate the consideration of patients' informed preferences. For some cancers, such as medullary thyroid carcinoma, these decisions may also involve significant out-of-pocket costs and effects on family members. Read More

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Tzila Zwas

Harefuah 2021 Jul;160(7):468-473

Institute of Nuclear Medicine, The Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel.

Introduction: Nuclear medicine (NM) in Israel started in 1952 with the use of isotopes in medicine, using I-131 for thyroid disorders, initiated by Prof. Czerniak, founder of the profession. The first institute opened in 1954. Read More

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The sodium iodide symporter (NIS): novel applications for radionuclide imaging and treatment.

Endocr Relat Cancer 2021 Jul 1. Epub 2021 Jul 1.

J Morris, Division of Endocrinology, Diabetes, Metabolism and Nutrition, and Division of Medical Oncology, Mayo Clinic Minnesota, Rochester, United States.

Cloning of the sodium iodide symporter (NIS) 25 years ago has opened an exciting chapter in molecular thyroidology with the characterization of NIS as one of the most powerful theranostic genes and the development of a promising gene therapy strategy based on image-guided selective NIS gene transfer in non-thyroidal tumors followed by application of 131I or alternative radionuclides, such as 188Re and 211At. Over the past 2 decades significant progress has been made in the development of the NIS gene therapy concept, from local NIS gene delivery, towards promising new applications in disseminated disease, in particular, through the use of oncolytic viruses, non-viral polyplexes, and genetically engineered MSCs as highly effective, highly selective and flexible gene delivery vehicles. In addition to allowing the robust therapeutic application of radioiodine in non-thyroid cancer settings, these studies have also been able to take advantage of NIS as a sensitive reporter gene that allows temporal and spatial monitoring of vector biodistribution, replication, and elimination - critically important issues for preclinical development and clinical translation. Read More

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3D Printed Larynx as a Novel Simulation Tool for Window Elaboration in Medialization Laryngoplasty.

J Voice 2021 Jul 10. Epub 2021 Jul 10.

Division of Otolaryngology, Pontificia Universidad Javeriana, Hospital Universitario San Ignacio, Bogotá, Colombia.

Objective: Surgical simulation training in residents has declined due to the limited exposure to cadaveric specimens. Three-dimensional (3D)-printing technology is rapidly taking an important role in different medical areas, especially in surgical specialties. It provides an alternative for resident simulation practices and for developing surgical skills before exposure to real settings. Read More

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Growth hormone cocktail improves hepatopulmonary syndrome secondary to hypopituitarism: A case report.

World J Clin Cases 2021 Jun;9(18):4852-4858

Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.

Background: Metabolic associated fatty liver disease frequently occurs in patients with hypopituitarism and growth hormone (GH) deficiency. Some patients may develop to hepatopulmonary syndrome (HPS). HPS has a poor prognosis and liver transplantation is regarded as the only approach to cure it. Read More

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Multiple endocrine neoplasia type 1 - a case report.

Pol Merkur Lekarski 2021 Jun;49(291):217-220

I.Ya. Horbachevsky Ternopil National Medical University of Ministry of Health Care of Ukraine.

Multiple endocrine neoplasia type 1 is a rare hereditary disease with an autosomal dominant type of inheritance characterized by high penetrance and the presence of hyperplasia and neoplasia in at least two different endocrine organs. The most often synchronously or consistently developing tumors are in the thyroid glands, the gastrointestinal tract and the adenohypophysis.

A Case Study: A patient 41-year-old with multiple endocrine neoplasia type 1 was treated with radiolabeled somatostatin analogues as a new promising treatment for patients with inoperable or metastatic neuroendocrine tumors. Read More

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Prognostic factors of restrictive myopathy in thyroid eye disease.

Sci Rep 2021 Jul 2;11(1):13781. Epub 2021 Jul 2.

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Korea.

To investigate the prognostic factors of extraocular muscle restriction in patients with thyroid eye disease (TED), 65 patients with TED and restrictive myopathy were evaluated. Demographics, clinical activity score (CAS), smoking status, thyroid disease status, thyroid hormone status, thyroid autoantibody status, orbital computed tomography (CT) scan at initial presentation, and treatment regimens were assessed. The movements of the most severely affected extraocular muscles were categorized into five grades. Read More

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Prevalence of incidental thyroid malignancy on routine F-fluorodeoxyglucose PET-CT in a large teaching hospital.

Eur J Hybrid Imaging 2020 Nov 16;4(1):21. Epub 2020 Nov 16.

Department of Radiology, Ninewells Hospital, James Arrott Drive, Dundee, DD2 1SY, Scotland, UK.

Purpose: To quantify incidental thyroid pathology including malignancy on routine F-FDG PET-CT scans To compare standardised uptake values (SUV) in thyroid malignancy subtypes METHODS AND MATERIALS: This is a retrospective study of all F-FDG PET-CT scans (n = 6179) performed in a teaching hospital between June 2010 and May 2019. RIS database search of reports for the word "thyroid" was performed. Studies with evidence of thyroid uptake were included. Read More

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November 2020

Photobiomodulation laser therapy in a Lenvatinib-related osteonecrosis of the jaw: A case report.

J Clin Exp Dent 2021 Jun 1;13(6):e626-e629. Epub 2021 Jun 1.

Oral Medicine and Oral Surgery Department, University Institute of Health Sciences (IUCS), Gandra 4585-116, Portugal.

Background: Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse drug reaction often presenting as a post-surgery complication that may interfere in the quality of the patient's life. In the last decade, additionally to bisphosphonates, other drugs have been associated with MRONJ including other antiresorptive, antiangiogenic or multitarget drugs such as levantinib. The data on MRONJ associated to lenvatinib is scarce with no guidelines for best management option. Read More

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Early benefits of a secondary fracture prevention programme.

Hip Int 2021 Jun 27:11207000211027476. Epub 2021 Jun 27.

Shaare Zedek Medical Centre, Jerusalem, Israel.

Introduction: The most successful programme for secondary fracture prevention is the FLS (fracture liaison service) model. Our orthopaedic department carried out a prospective randomised study to measure the effectiveness of a 4-step intervention programme. The findings in this study reveal important additional clinical benefits to having an orthopaedic-based FLS programme and evaluates the usefulness of fracture risk tools. Read More

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Added Value of Postoperative Radioiodine Scan for Staging and Risk Stratification in Papillary Thyroid Microcarcinoma.

J ASEAN Fed Endocr Soc 2021 27;36(1):64-68. Epub 2021 Apr 27.

Nuclear Medicine Division, Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Objective: The complete staging and risk stratification of Papillary thyroid microcarcinoma (PTMC) is usually not done due to its theoretically low recurrence rates. This study aimed to determine the value of postoperative radioiodine diagnostic scan and SPECT/CT for the accurate staging and risk stratification in PTMC patients.

Methodology: This study was a retrospective review of PTMC patients from January 2014 to May 2017 who underwent I-131 scans. Read More

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A case report of concurrence of aberrant extracranial internal carotid artery and nonrecurrent laryngeal nerve in a patient of advanced thyroid carcinoma invading hypopharynx.

Gland Surg 2021 May;10(5):1786-1791

Department of Otolaryngology, Head & Neck Surgery, Peking University First Hospital, Beijing, China.

Aberrant extracranial internal carotid artery and nonrecurrent laryngeal nerve (NRLN) are neurovascular anomalies, which clinicians should be aware of to prevent severe complications while performing transoral or open surgery in the head and neck area. These two variants can occur simultaneously because of similar etiology of embryological maldevelopment of arch arteries. In this study, a 64-year-old woman complaining of hoarseness presented a bulge in the left hypopharynx. Read More

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Bilateral breast myxedema caused by Graves' disease and responsive to multipoint subcutaneous injection of long-acting glucocorticoid: Case report.

Medicine (Baltimore) 2021 Jun;100(25):e26469

Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, Branch of National Clinical Research Center for Metabolic Disease, Hubei.

Rationale: With the absence of ophthalmopathy, thyroid dermopathy especially lesions at atypical locations is a very rare presentation. We herein report an original case of bilateral breast myxedema caused by Grave's disease.

Patient Concerns: A 21-year-old unmarried woman presented with a 4-month history of Grave's disease and a 1-month history of progressive bilateral breast enlargement. Read More

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Radiofrequency ablation for treatment of thyroid follicular neoplasm with low SUV in PET/CT study.

Int J Hyperthermia 2021 ;38(1):963-969

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Objectives: To evaluate the feasibility of radiofrequency ablation (RFA) on follicular neoplasm with low standard uptake value (SUV) in a Positron emission tomography (PET/CT) study.

Methods: From January 2018 to July 2019, 86 consecutive patients were diagnosed with follicular neoplasm. Of the patients, 28 with PET/CT scans were enrolled in this study. Read More

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Novel presentation of the c.1856A > G (p.Asp619Gly) TSHR gene-activating variant: relapsing hyperthyroidism in three subsequent generations manifesting in early childhood and an in vitro functional study.

Hormones (Athens) 2021 Jun 18. Epub 2021 Jun 18.

Vera Vavrova Laboratory/VIAL, Department of Pediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.

Background: Familial non-autoimmune hyperthyroidism is a rare disease caused by germline activating variants in the thyroid-stimulating hormone receptor (TSHR) gene. The c.1856A > G (p. Read More

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Tunica vaginalis testis metastasis as the first clinical manifestation of pancreatic adenocarcinoma: A case report.

World J Clin Cases 2021 Jun;9(17):4244-4252

Department of Andrology, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.

Background: Metastases from pancreas or ampullary malignancies are common, but the spread to testicle and paratesticular tissue is exceedingly rare. To the best of our knowledge, fewer than 30 cases have been reported in the literature. More rarely, metastasis to tunica vaginalis testis occurs without involvement of the testes and epididymis. Read More

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Factors predicting the risk of biochemical incomplete response in well-differentiated thyroid cancer after total thyroidectomy.

Nucl Med Commun 2021 Jun 14. Epub 2021 Jun 14.

Department of Nuclear Medicine Department of Biostatistics and Health Informatics, SGPGIMS, Lucknow, India.

Background: Differentiated thyroid cancer (DTC) is the most common endocrine carcinoma with an overall good prognosis. However, persistent or recurrent disease (P/R disease) and incomplete biochemical response (BIR) are causes of morbidity. Histopathology and TNM stage may not predict P/R disease and BIR in all patients. Read More

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Decreased Expression of Ileal Thyroid Hormone Transporters in a Hypothyroid Patient: A Case Report.

Front Endocrinol (Lausanne) 2021 26;12:664839. Epub 2021 May 26.

Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.

Background: Malabsorption of levothyroxine (LT4) is a common problem faced in clinical practice. It is usually solved, if there are no complexities including gastrointestinal absorption disorder, by taking medicines on an empty stomach and avoiding foods interfering with LT4. Herein we present a rare case of a patient exhibiting malabsorption of LT4 with decreased membranous expression of ileal transporters. Read More

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The Value of Pre-Ablative I-131 Scan for Clinical Management in Patients With Differentiated Thyroid Carcinoma.

Front Endocrinol (Lausanne) 2021 28;12:655676. Epub 2021 May 28.

Department of Internal Medicine, Division of Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.

Background: A diagnostic I-131 (Dx) scan is used to detect a thyroid remnant or metastases before treatment of differentiated thyroid cancer (DTC) with I-131. The aim of this study is to specify in which patients with DTC a Dx scan could have an additional value, by studying the effect of the Dx scan on clinical management.

Methods: Patients with DTC, treated with I-131 after thyroidectomy were included in this retrospective cohort study. Read More

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Synchronous incidental double parathyroid adenomas and papillary thyroid carcinoma: A case report with literature review.

Niger J Clin Pract 2021 Jun;24(6):954-963

Fellow, Breast and Endocrine Surgery, King Saud University, Riyadh, Saudi Arabia.

The association between parathyroid and thyroid diseases is not uncommon; however, the concurrent presence of parathyroid adenoma and thyroid cancer is rare. Awareness of this situation will enable clinicians to consider possible parathyroid pathology in patients with papillary thyroid cancer. The presence of parathyroid adenoma leading to primary hyperparathyroidism and the coexistence of thyroid papillary cancer is rare. Read More

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Synchronous thyroid cancer on the edge: Incidentalomas of 18F-FDG PET/CT in clinical practice.

Niger J Clin Pract 2021 Jun;24(6):937-942

Department of Nuclear Medicine, Gulhane Training and Research Hospital, Ankara, Turkey.

Aims: The objective of this study was to discuss the outcomes of the oncology patients whose PET/CT scans show incidental focal thyroid 18F-FDG uptake.

Methods: This retrospective analysis examined 2575 18F-FDG PET/CT scans from 1803 patients with no known thyroid cancer history. The survival rates were analyzed for patients with and without cytopathological evaluation. Read More

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