21,424 results match your criteria thromboembolism medical


Primary pulmonary artery sarcoma versus pulmonary thromboembolism: a multimodal imaging comparison.

J Thromb Thrombolysis 2021 May 7. Epub 2021 May 7.

Gonda Vascular Center, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

Primary pulmonary artery sarcoma (PPAS) is a rare malignancy that is commonly mistaken for pulmonary embolism due to similarities in clinical presentation and radiographic findings. Distinct radiographic findings to help differentiate between the two diseases are highlighted in the case presented. (1) Several nuances in various imaging modalities have been identified to help distinguish pulmonary artery sarcoma from pulmonary thromboembolic disease. Read More

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Prevalence of Venous Thromboembolism Following Acute Spinal Cord Injury in an Urban Inner City Hospital.

Int J Spine Surg 2021 May 7. Epub 2021 May 7.

Temple University Department of Orthopedic Surgery and Sports Medicine, Philadelphia, Pennsylvania.

Background: Venous thromboembolism (VTE) is known to occur at high rates in patients who suffer spinal cord injury (SCI). Large population studies in the United States have shown a prevalence of approximately 4-5%, with some studies suggesting higher prevalence. While the specific mechanism behind increased VTE incidence in the SCI population is unknown, it is likely tied to immobility and functional decline. Read More

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Timing of bleeding and thromboembolism associated with endoscopic submucosal dissection for gastric cancer in Japan.

J Gastroenterol Hepatol 2021 May 7. Epub 2021 May 7.

Department of Gastroenterology, Kanazawa University Hospital.

Objective: This study aimed to reveal the timing of bleeding and thromboembolism associated with endoscopic submucosal dissection (ESD) for early gastric cancer (EGC).

Methods: We retrospectively reviewed 10,320 patients who underwent ESD for EGC during November 2013-October 2016. We evaluated overall bleeding rates and their inter-group differences. Read More

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Diagnostic Value of D-dimer in Detecting Pulmonary Embolism in Patients with Acute COPD Exacerbation.

Tanaffos 2020 Dec;19(4):371-379

Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Signs and symptoms of chronic obstructive pulmonary disease (COPD) exacerbation may overlap with pulmonary embolism. Patients with acute COPD exacerbations have higher level of D-dimer which may D-dimer lead to false detection of pulmonary thromboembolism (PTE). In this study diagnostic value of D-dimer for diagnosis of pulmonary embolism during acute exacerbation in patients with COPD was investigated. Read More

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December 2020

Clinical Utility of Red Cell Distribution Width in Patients with Pleural Effusion.

Tanaffos 2020 Dec;19(4):364-370

Tuberculosis and Lung Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Background: The red cell distribution width (RDW) value has been recently recognized as a valuable biomarker in clinical practice. The RDW value has not been evaluated so far in patients with pleural effusion. Thus, this study aimed to investigate whether RDW could distinguish between exudative and transudative pleural effusions. Read More

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December 2020

Associations with thrombosis are stronger for antiphosphatidylserine/prothrombin antibodies than for the Sydney criteria antiphospholipid antibody tests in SLE.

Lupus 2021 May 6:9612033211014570. Epub 2021 May 6.

Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

Objectives: Antiphosphatidylserine/prothrombin complex antibodies (aPS/PT) are risk factors for thrombosis, yet further validation of their clinical relevance in different ethnic groups is required. We investigated the performance of aPS/PT of IgA/G/M isotypes among Sudanese and Swedish systemic lupus erythematosus (SLE) patients.

Methods: Consecutive SLE patients/matched controls from Sudan (n = 91/102) and Sweden (n = 332/163) were included. Read More

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Safety Monitoring of the Janssen (Johnson & Johnson) COVID-19 Vaccine - United States, March-April 2021.

MMWR Morb Mortal Wkly Rep 2021 May 7;70(18):680-684. Epub 2021 May 7.

CDC COVID-19 Response Team.

On February 27, 2021, the Food and Drug Administration (FDA) issued an Emergency Use Authorization (EUA) for Janssen (Ad.26.COV2. Read More

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Biopsy of an intracardiac paraganglioma in a dog using a fluoroscopically guided endovascular technique.

J Vet Intern Med 2021 May 6. Epub 2021 May 6.

Department of Pathology, Microbiology, and Immunology, University of California-Davis, Davis, California, USA.

A 10-year-old female spayed mixed breed dog was evaluated for diarrhea and vomiting. Diagnostic imaging demonstrated the presence of an intracardiac mass. A modified Seldinger technique was used to access the right jugular vein, and an endomyocardial biopsy forceps was introduced through a sheath to obtain several biopsies. Read More

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Homoarginine and methylarginines independently predict long-term outcome in patients presenting with suspicion of venous thromboembolism.

Sci Rep 2021 May 5;11(1):9569. Epub 2021 May 5.

Department of Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.

Endogenous arginine derivatives homoarginine, asymmetric dimethylarginine (ADMA) and symmetric dimethyarginine (SDMA) are independent mortality predictors in atherosclerotic cardiovascular disease (CVD). Our study reports the first analysis, whether homoarginine, ADMA and SDMA predict venous thromboembolism (VTE) recurrence and overall mortality in patients with suspected acute VTE. We assessed serum levels of homoarginine, ADMA and SDMA by LC-MS/MS in 865 individuals from a prospective consecutive cohort of patients with clinical suspicion of VTE. Read More

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Screening for the presence of scleroedema adultorum of Buschke in patients with diabetes mellitus: newly diagnosed patients had a high prevalence of dyslipidaemia.

Lipids Health Dis 2021 May 5;20(1):47. Epub 2021 May 5.

Department of Rheumatology and Immunology, Medical School, University of Pécs, Akác u. 1, Pécs, H-7632, Hungary.

Background: Scleroedema adultorum of Buschke is a rare disorder characterized by fibromucinous thickening of the dermis that manifests mainly at the nape of the neck and on the upper back and shoulders. This study screened patients with diabetes mellitus for skin hardening caused by scleroedema adultorum of Buschke and characterized the clinical and laboratory findings in patients with newly identified cases, with a focus on lipid metabolism abnormalities and vascular complications.

Methods: Out of 113 consecutive patients with diabetes, 11 (9. Read More

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Prevalence of atrial fibrillation and outcomes in older long-term care residents: a systematic review.

Age Ageing 2021 May;50(3):744-757

Department of Cardiovascular and Metabolic Medicine, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.

Background: anticoagulation is integral to stroke prevention for atrial fibrillation (AF), but there is evidence of under-treatment in older people in long-term care (LTC).

Objective: to synthesise evidence on the prevalence and outcomes (stroke, mortality or bleeding) of AF in LTC and the factors associated with the prescription of anticoagulation.

Methods: studies were identified from Medline, CINAHL, PsycINFO, Scopus and Web of Science from inception to 31 October 2019. Read More

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Soluble P-selectin levels in patients with obstructive sleep apnea: a systematic review and meta-analysis.

Eur Arch Otorhinolaryngol 2021 May 5. Epub 2021 May 5.

Department of Internal Medicine, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, 310022, China.

Purpose: Obstructive sleep apnea (OSA) patients are at increased risk for cardiovascular disease, stroke, atherosclerosis, hypertension, and venous thromboembolism. Elevated soluble P-selectin (sP-selectin) levels are also associated with increased risk of above diseases. But whether sP-selectin levels in OSA patients are higher than their counterparts remain unclear, since previous studies yielded inconsistent results. Read More

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Acute Limb Ischemia as the Initial Severe Presentation in COVID-19.

Cureus 2021 Mar 31;13(3):e14226. Epub 2021 Mar 31.

Cardiology, St. Joseph's University Medical Center, Paterson, USA.

Coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is characterized by an overwhelming inflammatory response in a subset of patients, resulting in respiratory compromise, multiorgan failure, and death. A common complication seen in patients hospitalized with COVID-19 infections is the development of venous and arterial thromboemboli. This occurs especially in patients who suffer from severe respiratory or systemic manifestations on the COVID-19 spectrum of disease. Read More

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Knowledge, attitude, and practice regarding atrial fibrillation among primary care physicians: the potential role of postgraduate training.

Malays Fam Physician 2021 Mar 7;16(1):39-49. Epub 2021 Feb 7.

MFamMed (UM), FRACGP, FAMM. Professor, Department of Family Medicine, International Medical University, Seremban Campus, Seremban, Negeri Sembilan, Malaysia.

Introduction: Atrial fibrillation (AF) is known to lead to stroke and thromboembolism, causing a five-fold increase in the risk of stroke and almost doubling the mortality rate. Optimal anticoagulant therapy is effective in reducing AF-related death. However, prescription of anticoagulants in AF in East Asian countries has been low, ranging from 0. Read More

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A case of inferior vena cava atresia complicated by bilateral deep vein thrombosis.

Radiol Case Rep 2021 Jun 18;16(6):1548-1551. Epub 2021 Apr 18.

Division of Interventional Radiology, Akron Children's Hospital, 214 W Bowery St, Akron, Akron, OH, 44308, USA.

In this report, we describe a case of deep vein thrombosis with suspected congenital inferior vena cava atresia treated with thrombolysis, angioplasty, and bilateral "kissing" iliac stent placement. An 18-year-old male presented with left common iliac vein thrombus and suspected congenital inferior vena cava atresia. He was treated over 4 days and discharged on anticoagulation which was continued long-term. Read More

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Complications of thoracoscopic talc insufflation for the treatment of malignant pleural effusions: a meta-analysis.

J Cardiothorac Surg 2021 May 4;16(1):125. Epub 2021 May 4.

Department of Chest Surgery, The Fourth Medical Center of PLA General Hospital, No.51, Fucheng Road, Haidian District, Beijing, 100048, China.

Background: Talc pleurodesis is an effective treatment for malignant pleural effusions (MPEs). This study was designed to estimate complication rates of thoracoscopic talc insufflation.

Methods: Literature search was conducted in electronic databases and studies were selected if they reported complication rates of thoracoscopic talc insufflation in cancer patients with MPEs. Read More

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Papillary Fibroelastoma in Differential Diagnosis of Left Atrial Appendage Masses.

Tex Heart Inst J 2021 Jan;48(1)

Department of Cardiology, University of Rostock Heart Center, Rostock, Germany.

Papillary fibroelastomas are benign tumors that usually originate from cardiac valves but may have other endocardial origins. We report the cases of 2 patients in whom left atrial appendage masses were initially diagnosed as thrombus. They were treated for embolic stroke and their symptoms resolved; however, their left atrial appendage masses did not regress. Read More

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January 2021

COVID-19-related coagulopathy: a review of pathophysiology and pharmaceutical management.

Cell Biol Int 2021 May 4. Epub 2021 May 4.

Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

December 2019 will never be forgotten in the history of medicine when an outbreak of pneumonia of unknown etiology in Wuhan, China sooner or later prompted the World Health Organization (WHO) to issue a public health warning emergency. This is not the first nor will it be the last time that a member of β-coronaviruses (CoVs) is waging a full-scale war against human health. Notwithstanding the fact that pneumonia is the primary symptom of the novel coronavirus (2019nCoV; designated as SARS-CoV-2), the emergence of severe disease mainly due to the injury of non-pulmonary organs at the shadow of coagulopathy leaves no choice, in some cases, rather than a dreadful death. Read More

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Cancer is associated with inferior outcome in patients with ischemic stroke.

J Neurol 2021 May 4. Epub 2021 May 4.

Department of Neurology, University Hospital and University of Zurich, CH-8091, Zurich, Switzerland.

Background: Whether patients with stroke and cancer exhibit specific characteristics has remained controversial.

Methods: Medical records of patients with ischemic stroke in 2014 or 2015 registered in the Swiss Stroke Registry of Zurich were retrospectively analyzed and integrated with regional cancer registry data. Associations of clinical and outcome parameters with cancer diagnosed up to 5 years prior to stroke were tested. Read More

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Fondaparinux Pre-, Peri-, and/or Postpartum for the Prophylaxis/Treatment of Venous Thromboembolism (FondaPPP).

Clin Appl Thromb Hemost 2021 Jan-Dec;27:10760296211014575

Aspen Pharma, München, Germany.

We analyzed data for women who received fondaparinux for ≥7 days during pregnancy. The study retrospectively included women who received fondaparinux pre-, peri- and/or postpartum for ≥7 days for prophylaxis/venous thromboembolism (VTE) treatment at German specialist centers (2004-2010). Data on pregnancy, VTE risk factors, anticoagulant treatment, pregnancy outcome and adverse events were extracted from medical records. Read More

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Atrial cardiopathy in embolic stroke of undetermined source.

Brain Behav 2021 May 4:e02160. Epub 2021 May 4.

Department of Neurology, Beijing Shijiitan Hospital, Capital Medical University, Beijing, China.

Introduction: Atrial cardiopathy is one of the most common potential sources of thromboembolism for embolic stroke of undetermined source (ESUS). The study aims to investigate the incidence of atrial cardiopathy (defined by severe left atrial enlargement (sLAE) or elevated serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) > 250 pg/ml) in patients with ESUS and compare with other stroke subtypes.

Methods: We retrospectively collected data of 936 consecutive patients with diffusion-weighted imaging-confirmed acute ischemic stroke. Read More

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Changes of fibrinolytic system in thrombolytic resuscitation of pulmonary thromboembolism-induced cardiac arrest model.

Int Wound J 2021 May 4. Epub 2021 May 4.

Department of Emergency, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

The objective of this study is to explore the changes in the coagulation and fibrinolysis system in an animal model with pulmonary embolism after cardiopulmonary bypass and to provide a theoretical basis for clinical practice. An animal model of cardiac arrest due to pulmonary embolism was established for venous thrombus (10-15 mL) in the left external jugular vein of 21 pigs. Computed tomography (CT) pulmonary arteriography was performed after the recovery of the underlying state, cardiac arrest state and spontaneous circulation, and then thrombolysis and cardiopulmonary resuscitation (recombinant tissue plasminogen activator [t-PA] 50 mg) were performed immediately. Read More

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Perioperative Safety of Tofacitinib in Surgical Ulcerative Colitis Patients.

Colorectal Dis 2021 May 3. Epub 2021 May 3.

Division of Colon and Rectal Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Background: Literature regarding monoclonal antibodies and increased postoperative complications in inflammatory bowel disease remains controversial. No study has investigated tofacitinib. We sought to determine preoperative exposure to small molecule inhibitors, tofacitinib, and postoperative outcomes. Read More

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Atrial fibrillation evolution and rhythm control strategy following left appendage closure: new insights from the prospective FLAAC registry.

BMC Cardiovasc Disord 2021 May 3;21(1):227. Epub 2021 May 3.

Inserm, CIC 1430, Henri Mondor University Hospital, Creteil, France.

Background: Percutaneous left atrial appendage (LAA) closure is an alternative to oral anticoagulation (OAC) for atrial fibrillation (AF) patients with high thromboembolism risk, particularly with contraindications to OAC. The LAA itself could possess proarrhythmogenic properties. As patients undergoing LAA closure could be candidates for cardioversion or ablation, we aimed to evaluate AF disease progression following LAA closure and the outcome of patients undergoing a rhythm control strategy after the procedure. Read More

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The Clinical Applicability of Primary Thromboprophylaxis in Ambulatory Patients With Pancreatic Cancer.

Pancreas 2021 Apr;50(4):494-499

Section of Thrombosis and Benign Hematology, The University of Texas MD Anderson Cancer Center, Houston, TX.

Abstract: Thromboembolism is a leading cause of death in ambulatory patients with cancer. Patients with pancreatic adenocarcinoma have a very high risk of developing venous thromboembolism, especially within the first 6 months of diagnosis. Although primary thromboprophylaxis could reduce this risk, there are unresolved questions concerning choice of agents for anticoagulation, duration of anticoagulation treatment, and criteria for patient selection. Read More

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eSIMPLER: A Dynamic, Electronic Health Record-Integrated Checklist for Clinical Decision Support During PICU Daily Rounds.

Pediatr Crit Care Med 2021 May 3. Epub 2021 May 3.

Division of Critical Care Medicine, Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, MA. Computational Health Informatics Program, Boston Children's Hospital, Boston, MA. Department of Anaesthesia, Harvard Medical School, Boston, MA. Department of Cardiovascular and Critical Care Nursing, Medical-Surgical Intensive Care Unit, Boston Children's Hospital, Boston, MA. Anesthesia Information Services, Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, MA.

Objectives: Design, implement, and evaluate a rounding checklist with deeply embedded, dynamic electronic health record integration.

Design: Before-after quality-improvement study.

Setting: Quaternary PICU in an academic, free-standing children's hospital. Read More

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New-Onset Depression After Total Knee Arthroplasty: Consideration of the At-Risk Patient.

J Arthroplasty 2021 Apr 18. Epub 2021 Apr 18.

Department of Orthopaedic Surgery, Atlanta, GA.

Background: Postoperative new-onset depression (NOD) has gained recent attention as a previously unrecognized complication which may put patients at risk for poor outcomes after elective total hip arthroplasty. We aimed to investigate risk factors for the development of NOD after total knee arthroplasty (TKA) and assess its association with postoperative complications.

Methods: This is a retrospective, population-level investigation of elective TKA patients. Read More

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Diagnostic accuracy of D-Dimer testing for recurrent venous thromboembolism: A systematic review with meta-analysis.: VTE recurrence and D-dimer.

Eur J Intern Med 2021 Apr 28. Epub 2021 Apr 28.

Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.

Objective: Venous thromboembolism (VTE) recurrence is a major concern after a first symptomatic episode, potentially impacting survival and healthcare needs in community, hospital and rehabilitation settings. We evaluated the association of D-Dimer positivity after oral anticoagulant therapy (OAT) discontinuation with VTE recurrence.

Methods: PubMed, Web of Science, Scopus and EMBASE databases were systematically searched. Read More

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Empiric use of anticoagulation in hospitalized patients with COVID-19: a propensity score-matched study of risks and benefits.

Biomark Res 2021 May 1;9(1):29. Epub 2021 May 1.

Department of Medicine, New York City Health + Hospitals, Lincoln Medical Center, Bronx, New York, USA.

Background: Hospitalized patients with COVID-19 demonstrate a higher risk of developing thromboembolism. Anticoagulation (AC) has been proposed for high-risk patients, even without confirmed thromboembolism. However, benefits and risks of AC are not well assessed due to insufficient clinical data. Read More

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