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Cryopreservation Studies on Silver Carp (Hypophthalmichthys molitrix) Embryos.

Cryo Letters 2021 May-Jun;42(3):178-187

3Department of Animal and Fish Production, College of Agricultural and Food Sciences, King Faisal University, Al-Ahsa, Kingdom of Saudi Arabia.

Background: Cryopreservation is an effective tool for the preservation of live biological materials.

Objective: This study examined the suitability of cryopreservation protocols and the effectiveness of ultrasound for silver carp embryos.

Materials And Methods: Embryos at three developmental stages were exposed to 10, 15, 20, and 25% of five cryoprotectants (CPAs), namely propylene glycol (PG), dimethylformamide (DFA), DMSO, MeOH, and ethylene glycol (EG) for 20 min. Read More

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Management of childhood and adolescent latent tuberculous infection (LTBI) in Germany, Austria and Switzerland.

PLoS One 2021 10;16(5):e0250387. Epub 2021 May 10.

Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité -Universitätsmedizin, Berlin, Germany.

Background: Majority of active tuberculosis (TB) cases in children in low-incidence countries are due to rapid progression of infection (latent TB infection (LTBI)) to disease. We aimed to assess common practice for managing paediatric LTBI in Austria, Germany and Switzerland prior to the publication of the first joint national guideline for paediatric TB in 2017.

Methods: Online-based survey amongst pediatricians, practitioners and staff working in the public health sector between July and November 2017. Read More

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First Report of Alfalfa Anthracnose Caused by in Xinjiang, China.

Plant Dis 2021 May 10. Epub 2021 May 10.

Bazhou Agricultural Technology Promotion Center, plant protection , korla, xinjiang, China;

Alfalfa ( L.) is widely planted in the world as one of the most important leguminous forage crops, and it is also the first choice of forage crops for animal feed in Xinjiang. In June 2018, alfalfa plants with typical anthracnose symptoms were observed in 75% of alfalfa fields in Hutubi County, Xinjiang, China. Read More

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Exploring the association of early life physical activity and risk of dementia: a systematic review.

Minerva Med 2021 May 10. Epub 2021 May 10.

NESMOS Department, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.

Introduction: Physical activity has been included in the list of twelve modifiable risk factors for dementia, despite conflicting results from observational and controlled studies. In particular it is not clear whether physical inactivity near the time of dementia diagnosis is a consequence or cause of dementia. We review all available studies reporting the possible association between having engaged in PA before 60 years of age and the risk of dementia. Read More

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Antibiotyping and Genotyping of Extensively Drug Resistant (XDR) Salmonella Spp. Isolated from Clinical Samples of Lahore, Pakistan.

J Appl Microbiol 2021 May 9. Epub 2021 May 9.

Department of Microbiology, Faculty of Life Sciences, University of Central Punjab, Lahore, Pakistan, 54590.

Aims: Antibiotic resistance is a major problem in Salmonella enterica serovar Typhi. Objective of this study was to evaluate the prevalence of XDR Salmonella among local population of Lahore and genotyping of isolates for antibiotic resistant genes.

Methods And Results: A total of 200 blood samples from suspected typhoid fever patients were collected. Read More

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Reference Values for Five-Repetition Chair Stand Test Among Middle-Aged and Elderly Community-Dwelling Chinese Adults.

Front Med (Lausanne) 2021 21;8:659107. Epub 2021 Apr 21.

Clinical Research Center, Shengjing Hospital of China Medical University, Shenyang, China.

Previous studies on the five-repetition chair stand test (CS-5) are limited by the representativeness of the sample or the lack of reference equations for CS-5. Defined reference values for CS-5 in a large population are not available for middle-aged and elderly Chinese adults. We established age- and sex-stratified reference values for CS-5 times in a large population in China, and to investigate the associations between demographic and anthropometric factors and CS-5 times. Read More

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Conversion surgery in patients with pancreatic cancer and peritoneal metastasis.

J Gastrointest Oncol 2021 Apr;12(Suppl 1):S110-S117

Department of Surgery, Kansai Medical University, Hirakata, Japan.

Background: Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal malignancies globally. We have previously explored the clinical efficacy of intraperitoneal (IP) paclitaxel therapy for patients with PDAC and peritoneal metastasis, which demonstrated favourable response and disease control rates. However, the real implications of conversion surgery after IP therapy remain unclear. Read More

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Toxicology and Pharmacokinetics Study of Intradiscal Injection of Simvastatin in Rabbits.

Front Pharmacol 2021 23;12:582309. Epub 2021 Apr 23.

Department of Orthopaedic Surgery, College of Medicine, University of Cincinnati, Cincinnati, OH, United States.

To test the pharmacokinetics and toxicology of whole organs and tissues after intradiscal injection of simvastatin in rabbits. To provide the information needed to support human clinical trials. Twelve male and twelve female rabbits were randomly divided into four groups: control group (0 mg/ml), low dose group (0. Read More

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Green banking initiatives: a qualitative study on Indian banking sector.

Environ Dev Sustain 2021 May 2:1-27. Epub 2021 May 2.

Department of Management, Birla Institute of Technology, Mesra (Ranchi), Noida Campus, A-7, Sector- 1, Gautam Buddh Nagar, Noida, 201301 India.

The environmental concern is on rise in all types of business; however, banking assumes a special niche due to its ability to influence the economic growth and development of the country. The present study proposes conceptual model of Green banking initiatives and studies the impact of three Green banking initiatives, viz. green products development, green corporate social responsibility and green internal process on two possible outcomes, viz. Read More

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Assessment of knowledge of oral pathologists and postgraduate students on safe laboratory practices during the COVID-19 pandemic.

J Oral Maxillofac Pathol 2020 Sep-Dec;24(3):437-445. Epub 2021 Jan 9.

Department of Oral Pathology and Microbiology, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India.

Background: Oral pathologists are involved in laboratory diagnosis and receive specimens of biopsy, oral cytologic smears and samples for hematology, biochemistry and microbiology and thus are at a risk for laboratory-acquired infections, which may occur inadvertently and can be considered as an occupational hazard.

Aim And Objectives: This study was conducted during the coronavirus disease (COVID-19) pandemic to assess the knowledge of oral pathologists and oral pathology postgraduate students regarding the safe laboratory practices, procedures and guidelines.

Materials And Methods: The study was a cross-sectional online questionnaire-based study. Read More

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January 2021

Audio-vestibular Abnormalities in Patients With Vitiligo: A Prospective Case-control Study.

Otol Neurotol 2021 Jun;42(5):e514-e520

Faculty of Medicine, Tanta University, Tanta, Egypt.

Introduction: Vitiligo is a disease that is characterized by a deficit of functional melanocytes all over the body including the inner ear.

Objectives: To study the effect of the reduction of melanocytes on the audio-vestibular system in patients with vitiligo.

Subjects And Methodology: Our study included 35 patients with vitiligo (study group) and 35 healthy volunteers (control group). Read More

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Reduced impact of viral load of HHV-6 in liquor on severity of AESD due to exanthema subitum: A case report and literature review.

Brain Dev 2021 May 7. Epub 2021 May 7.

Department of Neurology, Nagano Children's Hospital, Azumino, Japan. Electronic address:

Background: The most common causative pathogen of acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) was reported as HHV-6. Although excitotoxic injury with delayed neuronal death is considered to be a possible pathogenesis of AESD, the detailed pathophysiology remains unclear.

Case Presentation: We present a twelve-month-old girl with AESD due to HHV-6 primary infection. Read More

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Comparison of IVUS and multi-dimensional contrast imaging modalities for characterization of chronic occlusive iliofemoral venous disease: a systematic review.

J Vasc Surg Venous Lymphat Disord 2021 May 6. Epub 2021 May 6.

The RANE Center for Venous and Lymphatic Diseases, Jackson, MS 39216.

Background: Techniques to diagnose and treat chronic iliofemoral venous obstruction (CIVO) continue to evolve. Intravascular ultrasound (IVUS) displays real-time cross-sectional venous anatomy and can be used to guide venous interventions. However, being invasive, it is not a suitable initial screening tool. Read More

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Children's understanding of epilepsy: A qualitative study.

Epilepsy Behav 2021 May 5;120:107994. Epub 2021 May 5.

Usher Institute, The University of Edinburgh, UK; Muir Maxwell Epilepsy Centre, Centre for Clinical Brain Sciences, The University of Edinburgh, UK; Department of Paediatric Neurosciences, Royal Hospital for Sick Children, Edinburgh, UK; Child Life and Health, MRC Centre for Reproductive Health, The University of Edinburgh, Edinburgh, UK.

Purpose: To use a qualitative research approach to determine children's understandings of epilepsy and their epilepsy treatment.

Methods: Children aged 7-16 years with physician-confirmed active epilepsy (i.e. Read More

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StackIL6: a stacking ensemble model for improving the prediction of IL-6 inducing peptides.

Brief Bioinform 2021 May 8. Epub 2021 May 8.

Center of Data Mining and Biomedical Informatics, Faculty of Medical Technology, Mahidol University, Bangkok 10700, Thailand.

The release of interleukin (IL)-6 is stimulated by antigenic peptides from pathogens as well as by immune cells for activating aggressive inflammation. IL-6 inducing peptides are derived from pathogens and can be used as diagnostic biomarkers for predicting various stages of disease severity as well as being used as IL-6 inhibitors for the suppression of aggressive multi-signaling immune responses. Thus, the accurate identification of IL-6 inducing peptides is of great importance for investigating their mechanism of action as well as for developing diagnostic and immunotherapeutic applications. Read More

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Impact of wearing a surgical and cloth mask during cycle exercise.

Appl Physiol Nutr Metab 2021 May 7. Epub 2021 May 7.

University of Waterloo, 8430, Department of Kinesiology, BMH 1110, 200 University Avenue West, Waterloo, Ontario, Canada, N2L 3G1;

We sought to determine the impact of wearing cloth or surgical masks on the cardiopulmonary responses to moderate-intensity exercise. Twelve subjects (n=5 females) completed three, 8-min cycling trials while breathing through a: non-rebreathing valve (laboratory control), cloth, or surgical mask. Heart rate (HR), oxyhemoglobin saturation (SpO2), breathing frequency (Fb), mouth pressure, partial pressure of end-tidal carbon dioxide (PetCO2) and oxygen (PetO2), dyspnea, were measured throughout exercise. Read More

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The Impact of Locomotor Speed on the Human Metatarsophalangeal Joint Kinematics.

Front Bioeng Biotechnol 2021 20;9:644582. Epub 2021 Apr 20.

Key Laboratory of Bionic Engineering, Ministry of Education, Jilin University, Changchun, China.

This paper aims to further our previous study to investigate the effect of speed on the human metatarsophalangeal (MP) joint kinematics during running on level ground. The 3D motion of the foot segments was captured by a twelve-camera motion analysis system, and the ground reaction forces and moments were recorded by using a six-force plate array. The relative movement between the tarsometatarsi (hindfoot) and phalanges (forefoot) segments were recorded to obtain the 3D orientation and position of the functional axis (FA) of the MP joint. Read More

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Disease Spectrum of Breast Cancer Susceptibility Genes.

Front Oncol 2021 20;11:663419. Epub 2021 Apr 20.

Division of Surgical Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.

Background: Pathogenic variants in cancer susceptibility genes can increase the risk of a spectrum of diseases, which clinicians must manage for their patients. We evaluated the disease spectrum of breast cancer susceptibility genes (BCSGs) with the aim of developing a comprehensive resource of gene-disease associations for clinicians.

Methods: Twelve genes (, and ), all of which have been conclusively established as BCSGs by the Clinical Genome Resource (ClinGen) and/or the NCCN guidelines, were investigated. Read More

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Blood Purification Techniques, Inflammatory Mediators and Mortality in COVID-19 Patients.

Tanaffos 2020 Dec;19(4):291-299

Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Inflammatory mediators are an important component in the pathophysiology of the coronavirus disease 2019 (COVID-19). This study aimed to assess the effects of reducing inflammatory mediators using hemoperfusion (HP) and continuous renal replacement therapy (CRRT) on the mortality of patients with COVID-19.

Materials And Methods: Twelve patients with confirmed diagnosis of COVID-19 were included. Read More

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December 2020

Microvascular Dysfunction in Patients with Critical COVID-19, A Pilot Study.

Shock 2021 May 4. Epub 2021 May 4.

Karolinska Institutet, Department of Clinical Sciences, Danderyd University Hospital, Division of Internal medicine and Infectious diseases, Stockholm, Sweden.

Background: Endothelial and microvascular dysfunction may be a key pathogenic feature of severe COVID-19. The aim of this study was to investigate endothelial-dependent and endothelial-independent skin microvascular reactivity in patients with critical COVID-19.

Methods: Twelve patients with COVID-19 treated with non-invasive or invasive mechanical ventilation were included in the study. Read More

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Embodied Knowledge - the Phenomenon of Subjective Health Complaints reflected upon by Norwegian Psychomotor Physiotherapy specialists.

Physiother Theory Pract 2021 May 7:1-12. Epub 2021 May 7.

Faculty of Health Sciences, Department of Physiotherapy, Oslo Metropolitan University, Oslo, Norway.

: Many patients report subjective health complaints (SHCs) during primary health care consultations. : To elucidate Norwegian Psychomotor Physiotherapy (NPMP) specialists' clinical experiences in treatment of patients suffering from SHCs. : Twelve NPMP specialists were interviewed. Read More

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Clinical outcome of a conservative approach to giant cell tumor of ankle and foot bones.

Foot (Edinb) 2021 Jan 11;47:101766. Epub 2021 Jan 11.

Musculoskeletal Oncology, Max Institute of Cancer Care, Saket, New Delhi, India.

Giant cell tumor of the bone (GCTB) affecting foot and ankle is rare, and the literature available on their clinical behavior and reconstructive options is scarce. Many authors consider these sites a special subset with high rates of local recurrence. Eighteen patients with GCTB of foot and ankle were treated from (March 2014 to February 2020). Read More

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January 2021

The Healthy Taiwanese Eating Approach is inversely associated with all-cause and cause-specific mortality: A prospective study on the Nutrition and Health Survey in Taiwan, 1993-1996.

PLoS One 2021 6;16(5):e0251189. Epub 2021 May 6.

Institute of Population Health Science, National Health Research Institutes, Miaoli, Taiwan, R.O.C.

Background: Few longitudinal studies have investigated the association between foods/dietary pattern and mortality risk in the Asian population. We investigated the prospective association between foods/dietary pattern and risk of death among ethnic Chinese adults in Taiwan.

Methods: The study population included 2475 young and middle-aged adults (aged 18-65 years at baseline) who completed the questionnaires and physical examinations in the Nutrition and Health Survey in Taiwan from 1993 to 1996. Read More

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Initiation of student participation in practice: An audio diary study of international clinical placements.

Med Teach 2021 May 6:1-7. Epub 2021 May 6.

Parnassia Psychiatric Institute, The Hague, The Netherlands.

Background: Differences in professional practice might hinder initiation of student participation during international placements, and thereby limit workplace learning. This study explores how healthcare students overcome differences in professional practice during initiation of international placements.

Methods: Twelve first-year physiotherapy students recorded individual audio diaries during the first month of international clinical placement. Read More

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Efficacy of a low-dose praziquantel and fenbendazole protocol in the treatment of asymptomatic schistosomiasis in dogs.

J Vet Intern Med 2021 May 6. Epub 2021 May 6.

Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.

Background: Established treatment protocols for schistosomiasis (Heterobilharzia americana) in dogs are expensive. Anecdotal reports suggest that lower doses of praziquantel, combined with fenbendazole, may eliminate asymptomatic infections.

Objectives: Evaluate the efficacy of a low-dose praziquantel and fenbendazole protocol to manage asymptomatic schistosomiasis in dogs and compare fecal saline sedimentation (FSS) and fecal PCR (FPCR) for therapeutic monitoring. Read More

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Structural and Functional adaptation of the lingual papillae of the Egyptian fruit bat (Rousettus aegyptiacus): Specific Adaptive feeding Strategies.

Folia Morphol (Warsz) 2021 May 6. Epub 2021 May 6.

Faculty of Veterinary Medicine, Kafrelsheikh University, Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Kafrelsheikh University, 33511 Kafrelsheikh, Egypt., Kafrelsheikh, Egypt.

The current investigation was directed to clarify the correlations between the feeding strategy and lingual structure of the Egyptian fruit bat captured from the Egyptian east desert. The current work depends on twelve adult Egyptian fruit bats that observed grossly and with the help of the stereo, light, and scanning electron microscope. There were three types of the lingual papillae; one mechanical filiform and two gustatory (fungiform and circumvallate). Read More

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Donor defects after lymph vessel transplantation and free vascularized lymph node transfer: A comparison and evaluation of complications.

World J Transplant 2021 Apr;11(4):129-137

Division of Plastic Surgery, Department for Trauma Surgery, Orthopedics and Plastic Surgery, University Medical Center Goettingen, Goettingen 37075, Lower Saxony, Germany.

Background: Secondary lymphedema after surgical interventions is a progressive, chronic disease that is still not completely curable. Over the past years, a multitude of surgical therapy options have been described.

Aim: To summarize the single-center complications in lymph vessel (LVTx) and free vascularized lymph node transfer (VLNT). Read More

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Helpful post-diagnostic services for young onset dementia: Findings and recommendations from the Angela project.

Health Soc Care Community 2021 May 5. Epub 2021 May 5.

Faculty of Health Studies, Centre for Applied Dementia Studies, University of Bradford, Bradford, UK.

There is a significant lack of evidence regarding optimum models for service provision in young onset dementia (YOD). Our study aim was to gather detailed information about services experienced as helpful by those with YOD and family carers. The objective was to identify the core features of these services to inform service design, delivery and improvements. Read More

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Free-Breathing Abdominal Magnetic Resonance Fingerprinting Using a Pilot Tone Navigator.

J Magn Reson Imaging 2021 May 5. Epub 2021 May 5.

Department of Radiology, Case Western Reserve University, Cleveland, Ohio, USA.

Background: Quantitative T1 and T2 mapping in the abdomen provides valuable information in tissue characterization but is technically challenging due to respiratory motions. The proposed technique integrates magnetic resonance fingerprinting (MRF) and pilot tone (PT) navigator with retrospective gating to provide simultaneous quantification of multiple tissue properties in a single acquisition without breath-holding or patient set-up.

Purpose: To develop a free-breathing abdominal MRF technique for quantitative mapping in the abdomen. Read More

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COVID-19: first long-term care facility outbreak in the Netherlands following cross-border introduction from Germany, March 2020.

BMC Infect Dis 2021 May 4;21(1):418. Epub 2021 May 4.

Department of Sexual Health, Infectious Diseases, and Environmental Health, South Limburg Public Health Service, PO-Box 33, 6400 AA, Heerlen, The Netherlands.

Background: The Dutch province of Limburg borders the German district of Heinsberg, which had a large cluster of COVID-19 cases linked to local carnival activities before any cases were reported in the Netherlands. However, Heinsberg was not included as an area reporting local or community transmission per the national case definition at the time. In early March, two residents from a long-term care facility (LTCF) in Sittard, a Dutch town located in close vicinity to the district of Heinsberg, tested positive for COVID-19. Read More

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