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Efficient Synthesis of Topologically Linked Three-Ring DNA Catenanes.

Chembiochem 2016 06 23;17(12):1127-31. Epub 2016 May 23.

College of Food Science and Engineering, Ocean University of China, Qingdao, 266003, China.

Topologically controlled DNA catenanes are promising elements for the construction of molecular machines but present a significant effort in DNA nanotechnology. We report an efficient approach for preparing linear three-ring catenanes (L3C) composed of single-stranded DNA. The linking number was strictly controlled by using short complementary regions (6 nt) between each two DNA rings. Read More

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