76,885 results match your criteria three mental


Experiences of nursing students during clinical education in mental health clinics: A phenomenological qualitative study.

Nurse Educ Pract 2021 Jun 4;54:103113. Epub 2021 Jun 4.

Department of Psychiatric Nursing, Health Sciences Faculty, Zonguldak Bülent Ecevit University, Kozlu, Zonguldak, Turkey. Electronic address:

Aim: Nursing students have both positive and negative experiences during clinical education. This study was conducted to identify experiences of nursing students during clinical education in mental health clinics.

Design: This phenomenological qualitative design study was conducted with 4th year undergraduate nursing students from a university in Turkey to identify their experiences specifically in mental health clinics. Read More

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Benzofuranyl-2-imidazoles as imidazoline I receptor ligands for Alzheimer's disease.

Eur J Med Chem 2021 May 20;222:113540. Epub 2021 May 20.

Laboratory of Medicinal Chemistry (Associated Unit to CSIC), Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII, 27-31, E-08028, Barcelona, Spain. Electronic address:

Recent findings unveil the pharmacological modulation of imidazoline I receptors (I-IR) as a novel strategy to face unmet medical neurodegenerative diseases. In this work, we report the chemical characterization, three-dimensional quantitative structure-activity relationship (3D-QSAR) and ADMET in silico of a family of benzofuranyl-2-imidazoles that exhibit affinity against human brain I-IR and most of them have been predicted to be brain permeable. Acute treatment in mice with 2-(2-benzofuranyl)-2-imidazole, known as LSL60101 (garsevil), showed non-warning properties in the ADMET studies and an optimal pharmacokinetic profile. Read More

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Co-occurring risk and protective factors and regulatory behavior of infants living in low-income homes.

Infant Behav Dev 2021 Jun 9;64:101598. Epub 2021 Jun 9.

Crane Center for Early Childhood Research and Policy, The Ohio State University, United States.

Early self-regulation is a foundation for lifelong wellness and can be shaped by the interplay among several vital exposures. In this study, we examined the emergence of reliable profiles based upon exposure to risk and protective factors in infancy, determined if sociodemographic resources predict profile membership, and determined if these profiles predict early regulatory behaviors in a sample of infants reared in low-income homes. Data were collected from a sample of primarily Black or White mother-infant dyads living in low-income homes in the Midwest (n = 222) during the infants' first year of life (mean maternal age at enrollment: 26. Read More

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The representational structure of mental states generalizes across target people and stimulus modalities.

Neuroimage 2021 Jun 9;238:118258. Epub 2021 Jun 9.

Department of Psychology, Princeton University, Princeton, NJ 08544, United States; Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, United States.

Each individual experiences mental states in their own idiosyncratic way, yet perceivers can accurately understand a huge variety of states across unique individuals. How do they accomplish this feat? Do people think about their own anger in the same ways as another person's anger? Is reading about someone's anxiety the same as seeing it? Here, we test the hypothesis that a common conceptual core unites mental state representations across contexts. Across three studies, participants judged the mental states of multiple targets, including a generic other, the self, a socially close other, and a socially distant other. Read More

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Ensuring patient and public involvement in the transition to AI-assisted mental health care: A systematic scoping review and agenda for design justice.

Health Expect 2021 Jun 12. Epub 2021 Jun 12.

Surrey Heartlands Health and Care Partnership, Guildford and Waverley CCG, Guildford, UK.

Background: Machine-learning algorithms and big data analytics, popularly known as 'artificial intelligence' (AI), are being developed and taken up globally. Patient and public involvement (PPI) in the transition to AI-assisted health care is essential for design justice based on diverse patient needs.

Objective: To inform the future development of PPI in AI-assisted health care by exploring public engagement in the conceptualization, design, development, testing, implementation, use and evaluation of AI technologies for mental health. Read More

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Bioethics in Africa: A contextually enlightened analysis of three cases.

Dev World Bioeth 2021 Jun 11. Epub 2021 Jun 11.

Across sub-Saharan Africa, bioethics is an emerging field of scholarly inquiry, informed by contextual features distinct to the region. A cultural mix comprised of Euro-American influences, indigenous traditions, Christian faiths and Muslim communities, a bioethics for the sub-Saharan region must be responsive to this milieu. This paper asks, what values and methods can best promote the practice of bioethics in Africa? We set forth a strategy that leans one way or another in response to contextual features of a particular setting. Read More

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Pneumocephalus with meningitis secondary to an old traumatic anterior cranial fossa defect.

BMJ Case Rep 2021 Jun 11;14(6). Epub 2021 Jun 11.

Emergency Medicine, Kasturba Hospital Manipal, Manipal, Karnataka, India.

We report a case of a 30-year-old man who presented with altered mental status, fever, headache and vomiting for 3 days. An initial CT scan of the brain revealed the presence of pneumocephalus with a bony defect in the anterior cranial fossa. The pneumocephalus was not explained initially and the patient was re-examined for any signs of trauma to the face, and a review of the history revealed a series of three traumatic events months prior to this illness. Read More

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Prospective, Randomized, Double-Blinded Clinical Trial Comparing PEEK and Allograft Spacers in Patients Undergoing Transforaminal Lumbar Interbody Fusion Surgeries.

Spine J 2021 Jun 8. Epub 2021 Jun 8.

Boulder Neurosurgical Associates, Boulder, Colorado, USA; Justin Parker Neurological Institute, Boulder, Colorado, USA. Electronic address:

Background Context: Allograft and polyether-ether-ketone (PEEK) radiographic, biomechanical, histological properties have been extensively studied and both spacers have their advantages and shortcomings. There are no comparative randomized or double-blinded spinal fusion clinical trials reported to date.

Purpose: The study's primary objective was to prospectively investigate clinical and radiological outcomes in patients undergoing lumbar interbody fusions and randomized to receive either PEEK or structural bone allografts. Read More

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Identifying research priorities to improve the health of incarcerated populations: results of citizens' juries in Australian prisons.

Lancet Public Health 2021 Jun 8. Epub 2021 Jun 8.

School of Population Health, University of New South Wales (UNSW Sydney), Sydney, NSW, Australia.

Health disparities in incarcerated populations should guide investment in the health care and research of these communities. Although users of health-care services are important in providing input into decisions about research, the voices of people in prison are absent regarding research into their health. In this Health Policy paper, we present priorities for research into the health of people in prison according to people in prison themselves. Read More

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Persistent visual dysfunction following PRES due to COVID-19: Case series and literature review.

Eur J Neurol 2021 Jun 11. Epub 2021 Jun 11.

Department of Ophthalmology, Colorado University School of Medicine, 1675 North Aurora Ct. F731, Aurora, CO, 80045, USA.

Background: The full spectrum of neurological sequelae in COVID-19 is beginning to emerge. SARS-CoV-2 has the potential to cause both direct and indirect brain vascular endothelial damage through infection and inflammation that may result in long-term neurological signs and symptoms. We sought to illuminate persistent neuro-ophthalmological deficits that may be seen following posterior reversible encephalopathy syndrome (PRES) due to COVID-19. Read More

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The Implementation of Home Office Work in a Large Psychiatric University Hospital in Switzerland during the Covid-19 Pandemic: A Field Report.

JMIR Ment Health 2021 May 31. Epub 2021 May 31.

University Psychiatric Clinics Basel (UPK), University of Basel, Basel, CH.

Background: During the Covid-19 pandemic in 2020, psychiatric hospitals all over the world had to adapt their services to the prevailing governmental regulations. As a consequence, home office (HO) and telepsychiatry boomed.

Objective: To evaluate the potential of HO use, its adoption, and the association of HO use with employees' mental health in a large Psychiatric University Hospital in Switzerland. Read More

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Development and Validation of a Patient-Reported Outcome Measure of Ataxia.

Mov Disord 2021 Jun 11. Epub 2021 Jun 11.

Global Health Outcomes and Epidemiology, Biohaven Pharmaceuticals, New Haven, Connecticut, USA.

Background: Assessment of cerebellar ataxia has been confined to rating scales, gait laboratories, and wearable sensors agnostic to patient input.

Objectives: The objective of this study was to develop a Patient-Reported Outcome Measure of Ataxia.

Methods: (1) The conceptual framework, item pool development, and domain selection were developed using online surveys completed by 147 ataxia patients. Read More

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Influence of age on postural control during dual task: a centre of pressure motion and electromyographic analysis.

Aging Clin Exp Res 2021 Jun 11. Epub 2021 Jun 11.

Sport and Exercise Medicine Division, Department of Medicine, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy.

Background: Dual task influences postural control. A cognitive task seems to reduce muscle excitation during a postural balance, especially in older adults (OA).

Aim: The aim of this study is to evaluate the effect of three cognitive tasks on muscle excitation and static postural control in OA and young adults (YA) in an upright posture maintenance task. Read More

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Decellularized nerve extracellular matrix/chitosan crosslinked by genipin to prepare a moldable nerve repair material.

Cell Tissue Bank 2021 Jun 11. Epub 2021 Jun 11.

Department of Human Anatomy, College of Basic Medical Sciences, Binzhou Medical University, Yantai, 264003, People's Republic of China.

Decellularized nerve extracellular matrix (NECM) composited with chitosan are moldable materials suitable for spinal cord repair. But the rapid biodegradation of the materials may interrupt neural tissue reconstruction in vivo. To improve the stability of the materials, the materials produced by NECM and chitosan hydrogels were crosslinked by genipine, glutaraldehyde or ultraviolet ray. Read More

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[The sensorimotor domain in the research domain criteria system: progress and perspectives].

Nervenarzt 2021 Jun 11. Epub 2021 Jun 11.

Zentrum für Psychosoziale Medizin, Klinik für Allgemeine Psychiatrie, Universität Heidelberg, Heidelberg, Deutschland.

Over the past three decades research interest in hypokinetic, hyperkinetic, sensorimotor and psychomotor abnormalities in mental disorders has steadily increased. This development has led to an increasing number of scientific initiatives that have not only highlighted the clinical need for early detection of extrapyramidal motor symptoms, tardive dyskinesia and catatonia but also provided numerous neurobiological findings and clinically relevant results based on the pathology of the sensorimotor system in patients with mental disorders. In view of these developments in January 2019 the National Institute of Mental Health (NIMH) research domain criteria (RDoC) initiative introduced a sixth domain called the sensorimotor domain to address deficits in the sensorimotor system and associated behavioral abnormalities. Read More

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In Orthopaedic Speciality Care, Longer Explanations Are Not More Caring or More Satisfying.

Clin Orthop Relat Res 2021 Jun 11. Epub 2021 Jun 11.

Department of Surgery and Perioperative Care, Dell Medical School, the University of Texas at Austin, Austin, TX, USA.

Background: Research consistently documents no correlation between the duration of a musculoskeletal specialty care visit and patient experience (perceived empathy of the specialist and satisfaction with care). Based on a combination of clinical experience and other lines of research, we speculate that longer visits are often related to discordance between specialist and patient interpretation of symptoms and weighting of available test and treatment options. If this is true, then the specific duration of time discussing the specialist's interpretations and options with the patient (expertise transfer) might correlate with satisfaction with care and perceived empathy of the clinician even if the total visit time does not. Read More

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Longitudinal trajectories of metabolic syndrome on different neurocognitive domains: a cohort study from the Taiwan biobank.

Aging (Albany NY) 2021 Jun 11;13. Epub 2021 Jun 11.

Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China.

Metabolic syndrome (MetS) brings considerable effects on cognitive function, but trajectories within remain unclear. We investigated the interactions between distinct MetS components and cognitive domains. A total of 5693 participants from the Taiwan biobank during 2008-2018 were enrolled. Read More

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Short Term, Oral Supplementation with Optimized Curcumin Does Not Impair Performance Improvements Associated with High Intensity Interval Training.

J Diet Suppl 2021 Jun 11:1-14. Epub 2021 Jun 11.

School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO, USA.

Curcumin may improve athletic performance through a reduction in inflammation following exercise and improve mental states of well-being. The purpose of this investigation was to explore the effects of a 14 day HIIT intervention and oral supplementation with Longvida optimized curcumin on athletic performance, lactate response, and well-being. Sixteen males and twenty females participated in a double-blinded, randomized, placebo-controlled trial to explore the effects of Longvida(R) optimized curcumin (1. Read More

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EXPRESS: Stroke in India: a systematic review of the incidence, prevalence and case fatality.

Int J Stroke 2021 Jun 11:17474930211027834. Epub 2021 Jun 11.

The George Institute for Global Health, Mental Health, The University of New South Wales, Newtown, New South Wales, Australia.

Background: The burden of stroke is increasing in India; stroke is now the fourth leading cause of death and the fifth leading cause of disability. Previous research suggests that the incidence of stroke in India ranges between 105 and 152/100,000 people per year. However, there is a paucity of available data and a lack of uniform methods across published studies. Read More

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An evaluation of the nutritional status of elderly with the use of the MNA questionnaire and determination of factors contributing to malnutrition. A pilot study.

Rocz Panstw Zakl Hig 2021 ;72(2):175-183

University of Life Science, Faculty of Food Science and Biotechnology, Department of Chemistry, Akademicka street 15, 20-950, Lublin, Poland.

Background: In the elderly, nutrition significantly influences biological aging and physiological and pathological changes in the body. A balanced diet and physical activity are the key to good physical and mental health.

Objective: The aim of this study was: (1) to perform nutritional screening tests in senior citizens residing in eastern Poland and (2) to evaluate the risk of malnutrition in elderly people who live with their families, seniors who live independently, and residents of nursing homes. Read More

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January 2021

The added value of palliative day care centres: A full-population cross-sectional survey among clients and their family caregivers in Flanders, Belgium.

Health Soc Care Community 2021 Jun 11. Epub 2021 Jun 11.

End-of-Life Care Research Group, Vrije Universiteit Brussel (VUB) & Ghent University, Ghent, Belgium.

In addition to palliative care delivery at home or in hospital, palliative day care centres occupy an in-between position in palliative care. In palliative day care centres, multidisciplinary teams provide holistic care and support for people with (chronic) life-limiting conditions, or clients, in a homely surrounding, allowing them to remain living at home while attending a specialist palliative care service. This study aims to evaluate palliative day care centres from a user perspective. Read More

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Opinions and experiences of nursing students about evaluating the sexual health of individuals with mental disorders: A qualitative study.

Perspect Psychiatr Care 2021 Jun 10. Epub 2021 Jun 10.

Department of Mental Health and Psychiatric Nursing, Florence Nightingale Nursing Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Purpose: To explore the views and experiences of nursing students about evaluating the sexual health of individuals with mental disorders.

Design And Methods: A phenomenological approach was used. The purposeful sampling method gathered 11 nursing students. Read More

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Assembling the Career Firefighter Health Study cohort: A methods overview.

Am J Ind Med 2021 Jun 10. Epub 2021 Jun 10.

Bureau of Health Services, Fire Department of the City of New York, Brooklyn, New York, USA.

Background: Studies of World Trade Center (WTC)-exposed rescue/recovery workers report the increased occurrence of health conditions after work at the WTC disaster site. However, the extent to which these associations are due to WTC exposure is unclear, in part due to the lack of suitable comparison groups. Accordingly, we identified a previously assembled National Institute for Occupational Safety and Health (NIOSH) cohort of career firefighters from three US cities (n = 29,992). Read More

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Deep learning-based amyloid PET positivity classification model in the Alzheimer's disease continuum by using 2-[F]FDG PET.

EJNMMI Res 2021 Jun 10;11(1):56. Epub 2021 Jun 10.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.

Background: Considering the limited accessibility of amyloid position emission tomography (PET) in patients with dementia, we proposed a deep learning (DL)-based amyloid PET positivity classification model from PET images with 2-deoxy-2-[fluorine-18]fluoro-D-glucose (2-[F]FDG).

Methods: We used 2-[F]FDG PET datasets from the Alzheimer's Disease Neuroimaging Initiative and Korean Brain Aging Study for the Early diagnosis and prediction of Alzheimer's disease for model development. Moreover, we used an independent dataset from another hospital. Read More

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Neuroergonomic Stress Assessment with Two Different Methodologies, in a Manual Repetitive Task-Product Assembly.

Comput Intell Neurosci 2021 18;2021:5561153. Epub 2021 May 18.

Tecnológico Nacional De México, Instituto Tecnológico de Ciudad Juárez, División de Estudios de Posgrado e Investigación, Av. Tecnológico No. 1340 C.P. 32500 Cd. Juárez, Chihuahua, Mexico.

Emotions are a fundamental part of mental health and human behavior. In the workplace, optimal performance of employees is necessary for productivity enhancements and its relation to the quality of a manufacturing product, therefore leading a company to advantages and competitiveness. This means that the workplace staff must remain in a neutral or a calm emotional state, for an adequate job performance. Read More

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The Effect of Vocabulary Depth and Breadth on English Listening Comprehension Can Depend on How Comprehension Is Measured.

Front Psychol 2021 25;12:657573. Epub 2021 May 25.

School of Foreign Languages, Anhui Agricultural University, Hefei, China.

This study examines the relative contribution of vocabulary breadth (VB) and vocabulary depth (VD) to three different listening comprehension measures. One hundred and thirteen English majors were given VB and VD tests, and three listening comprehension tests. Based on three pairs of hierarchical multiple regression analyses, we found that the relative contribution of VB and VD varied across the three listening comprehension tests. Read More

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Measuring Prospective Imagery: Psychometric Properties of the Chinese Version of the Prospective Imagery Task.

Front Psychol 2021 25;12:645127. Epub 2021 May 25.

Center of Mental Health Education and Research, Jiangxi Normal University, Nanchang, China.

Objective: Prospective negative imagery is suggested to play an important role in the development and maintenance of anxiety and depression. The Prospective Imagery Task (PIT) was developed to assess prospective imagery. Given the importance of prospective imagery for mental health in the Chinese cultural context, our objective was to examine the psychometric properties of the PIT in a Chinese sample. Read More

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