Am J Gastroenterol 2021 Apr 8. Epub 2021 Apr 8.
University of California San Francisco, San Francisco, California, USA; National Institutes of Health Bethesda, Maryland, USA; University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA; Virginia Commonwealth University, Richmond, Virginia, USA; Massachusetts General Hospital; Harvard Medical School, Boston, Massachusetts, USA; Washington University School of Medicine, St. Louis, Missouri, USA; University of Michigan, Ann Arbor, Michigan, USA.
Introduction: Fatty liver disease (FLD) influences liver disease progression and liver cancer risk. We investigated the impact of FLD on liver disease severity in a large North American cohort with chronic hepatitis B virus (HBV).
Methods: Liver biopsies from 420 hepatitis B surface antigen-positive adults enrolled in the Hepatitis B Research Network and who were not on HBV therapy in the previous month were evaluated for inflammation and fibrosis. Read More