11,714 results match your criteria third ventricular

Endoscopic Endonasal Approach for Giant Pituitary Adenoma Occupying The Entire Third Ventricle: Surgical Results and A Review of Literature.

World Neurosurg 2021 Jul 19. Epub 2021 Jul 19.

Department of Neurosurgery , Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India - 695011. Electronic address:

Background: Pituitary macroadenomas, occasionally, disrupt the sellar diaphragm and extend directly to the third ventricle causing hydrocephalus.

Objective: We present the results of a single stage extended endoscopic approach for managing giant pituitary adenomas occupying the entire third ventricle.

Methods: A retrospective study of all giant pituitary adenomas, occupying the entire third ventricle, operated via the endoscopic endonasal approach between January 2016 and December 2020 was performed. Read More

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Endoscopic third ventriculostomy before surgery of third ventricle and posterior fossa tumours decreases the risk of secondary hydrocephalus and early postoperative complications.

Neurosurg Rev 2021 Jul 22. Epub 2021 Jul 22.

Department of Neurosurgery, Wroclaw Medical University, Borowska str. 213, 50-556, Wroclaw, Poland.

Endoscopic third ventriculostomy (ETV) is an effective treatment for obstructive hydrocephalus (HCP) at the level of third or fourth ventricle. To date, there is no consensus regarding its role as intervention preceding the operation of tumour removal. The aim of this prospective open-label controlled study is to assess if ETV prevents secondary HCP after tumour removal and if ETV influences the early results of tumour surgery. Read More

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Stem cell therapy for dilated cardiomyopathy.

Cochrane Database Syst Rev 2021 Jul 21;7:CD013433. Epub 2021 Jul 21.

Interdisciplinary Centre for Health Studies CIESAL, Universidad de Valparaíso, Viña del Mar, Chile.

Background: Stem cell therapy (SCT) has been proposed as an alternative treatment for dilated cardiomyopathy (DCM), nonetheless its effectiveness remains debatable.

Objectives: To assess the effectiveness and safety of SCT in adults with non-ischaemic DCM.

Search Methods: We searched CENTRAL in the Cochrane Library, MEDLINE, and Embase for relevant trials in November 2020. Read More

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Ictal asystole: an uncommon but significant cause of transient loss of consciousness-a case series.

BMJ Case Rep 2021 Jul 20;14(7). Epub 2021 Jul 20.

Department of Medicine for the Elderly, Queen Elizabeth University Hospital Campus, Glasgow, UK.

Ictal bradycardia and asystole are rare, but potentially serious complications of epileptic seizures. We present a case series of three such patients diagnosed through our syncope service. For two patients, treatment with anticonvulsant therapy alone achieved symptom control. Read More

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Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction.

Eur Heart J 2021 Jul 19. Epub 2021 Jul 19.

Department of Biology, Stanford University, Stanford, CA 94305, USA.

Aims: Non-compaction cardiomyopathy is a devastating genetic disease caused by insufficient consolidation of ventricular wall muscle that can result in inadequate cardiac performance. Despite being the third most common cardiomyopathy, the mechanisms underlying the disease, including the cell types involved, are poorly understood. We have previously shown that endothelial cell-specific deletion of the chromatin remodeller gene Ino80 results in defective coronary vessel development that leads to ventricular non-compaction in embryonic mouse hearts. Read More

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Complications of implantable cardioverter-defibrillator treatment in arrhythmogenic right ventricular cardiomyopathy.

Europace 2021 Jul 19. Epub 2021 Jul 19.

Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Aims: Treatment with implantable cardioverter-defibrillators (ICD) is a cornerstone for prevention of sudden cardiac death in arrhythmogenic right ventricular cardiomyopathy (ARVC). We aimed at describing the complications associated with ICD treatment in a multinational cohort with long-term follow-up.

Methods And Results: The Nordic ARVC registry was established in 2010 and encompasses a large multinational cohort of ARVC patients, including their clinical characteristics, treatment, and events during follow-up. Read More

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Predictive Modeling of Secondary Pulmonary Hypertension in Left Ventricular Diastolic Dysfunction.

Front Physiol 2021 1;12:666915. Epub 2021 Jul 1.

Department of Applied and Computational Mathematics and Statistics, University of Notre Dame, Notre Dame, IN, United States.

Diastolic dysfunction is a common pathology occurring in about one third of patients affected by heart failure. This condition may not be associated with a marked decrease in cardiac output or systemic pressure and therefore is more difficult to diagnose than its systolic counterpart. Compromised relaxation or increased stiffness of the left ventricle induces an increase in the upstream pulmonary pressures, and is classified as secondary or group II pulmonary hypertension (2018 Nice classification). Read More

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Left ventricular mural thrombi with multisystem thrombosis in patients with COVID-19 and myocardial injury: a case series.

Eur Heart J Case Rep 2021 Jun 26;5(6):ytab239. Epub 2021 Jun 26.

Division of Cardiology, Newark Beth Israel Medical Center, 201 Lyons Ave, Newark, NJ 07112, USA.

Background: Cardiovascular and thromboembolic complications have been reported in patients with Coronavirus disease-2019 (COVID-19)-related severe respiratory distress syndrome. Although myocarditis associated with COVID-19 pneumonia has been described, evidence of left ventricular (LV) mural thrombi with other multisystem events has not been reported.

Case Summary: We report two cases with severe COVID-19 pneumonia and myocardial injury with large LV thrombi and other multisystem thrombotic events. Read More

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Recent Experience: Corticosteroids as a First-line Therapy in Children With Multisystem Inflammatory Syndrome and COVID-19-related Myocardial Damage.

Pediatr Infect Dis J 2021 Jul 13. Epub 2021 Jul 13.

From the Cardiology Department, Mother and Child Health Institute of Serbia School of Medicine, University of Belgrade Immunology Department, Mother and Child Health Institute of Serbia Intensive Care Unit, Mother and Child Health Institute of Serbia Surgery Department, Mother and Child Health Institute of Serbia Institute of Medical Physiology "Rihard Burian", Belgrade, Serbia.

Background: Cardiovascular complications with myocarditis in multisystem inflammatory syndrome in children (MIS-C) associated with severe acute respiratory syndrome coronavirus 2 infection have been reported, but the optimal therapeutic strategy remains unknown.

Methods: A retrospective cohort study included 19 patients with acute left ventricular systolic dysfunction associated with MIS-C, average years of age 13.2 ± 3. Read More

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Transesophageal echocardiography probe induced recurrent VF in a child with severe RV dysfunction: Report of a rare case.

J Card Surg 2021 Jul 14. Epub 2021 Jul 14.

Department of Cardiac Anaesthesia and Cardiothoracic and Vascular Surgery, GB Pant Hospital (GIPMER), New Delhi, India.

The safety of transesophageal echocardiography (TEE) probes has been documented in pediatric patients (neonates, infants, and small children even < 2.5 kg). The overall safety profile of TEE probe is quite favorable with a reported incidence of complications of 1%-3%. Read More

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[Diagnostic value of FNDC5 in patients with subclinical diabetic cardiomyopathy].

Zhonghua Xin Xue Guan Bing Za Zhi 2021 Jul 24;49(7):687-693. Epub 2021 Jul 24.

Department of Endocrinology, Third Affiliated Hospital of Soochow University, Suzhou 213000, China.

To estimate the diagnostic value of fibronectin type Ⅲ-domain containing protein 5 (FNDC5) in subclinical diabetic cardiomyopathy. A total of 94 patients with type 2 diabetes (T2DM), who were hospitalized from April 2018 to June 2019 in the Third Affiliated Hospital of Soochow University, were enrolled in this study. Patients were divided into T2DM with cardiac dysfunction (subclinical DCM) group (=47) and T2DM without cardiac dysfunction (non-DCM) group (=47) according to echocardiography and gated myocardial perfusion imaging results. Read More

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J wave syndromes: What's new?: J wave syndromes.

Trends Cardiovasc Med 2021 Jul 10. Epub 2021 Jul 10.

Lankenau Institute for Medical Research, Wynnewood PA.

Among the inherited ion channelopathies associated with potentially life-threatening ventricular arrhythmia syndromes in nominally structurally normal hearts are the J wave syndromes, which include the Brugada (BrS) and early repolarization (ERS) syndromes. These ion channelopathies are responsible for sudden cardiac death (SCD), most often in young adults in the third and fourth decade of life. Our principal goal in this review is to briefly outline the clinical characteristics, as well as the molecular, ionic, cellular, and genetic mechanisms underlying these primary electrical diseases that have challenged the cardiology community over the past two decades. Read More

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The V6-V1 interpeak interval: a novel criterion for the diagnosis of left bundle branch capture.

Europace 2021 Jul 12. Epub 2021 Jul 12.

Geisinger Heart Institute, Geisinger Commonwealth School of Medicine, Wilkes-Barre, PA, USA.

Aims: We hypothesized that during left bundle branch (LBB) area pacing, the various possible combinations of direct capture/non-capture of the septal myocardium and the LBB result in distinct patterns of right and left ventricular activation. This could translate into different combinations of R-wave peak time (RWPT) in V1 and V6. Consequently, the V6-V1 interpeak interval could differentiate the three types of LBB area capture: non-selective (ns-)LBB, selective (s-)LBB, and left ventricular septal (LVS). Read More

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Long term effects of mild severity COVID‑19 on right ventricular functions.

Int J Cardiovasc Imaging 2021 Jul 12. Epub 2021 Jul 12.

Department of Cardiology, Suleyman Demirel University, Isparta, Turkey.

Coronavirus disease 2019 (COVID-19) is a newly recognized infectious disease that has spread rapidly. COVID-19 has been associated with a number of cardiovascular involvements, including ventricular functions. The aim of our study was to evaluate the right ventricular functions of mild severity COVID-19 patients 3 months after, and compare them to the right ventricular functions of healthy volunteers. Read More

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Postoperative hydrocephalus is a high-risk lethal factor for patients with low-grade optic pathway glioma.

Br J Neurosurg 2021 Jul 9:1-7. Epub 2021 Jul 9.

Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, PR China.

Objectives: To explore the prognostic factors of patients with low-grade optic pathway glioma (OPG) and the optimal treatment to reduce the incidence of postoperative hydrocephalus.

Patients And Methods: This single-center study retrospectively analyzed data from 66 patients with OPGs who underwent surgery. The patients were followed, and overall survival (OS) and progression-free survival (PFS) were determined. Read More

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Occult pulmonary arterial hypertension in patients with previous pulmonary tuberculosis.

Afr J Thorac Crit Care Med 2020 1;26(4). Epub 2020 Dec 1.

Division of Pulmonology, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Background: Pulmonary tuberculosis (TB) still causes a significant public healthcare burden. Despite successful treatment, TB can lead to permanent lung damage and pulmonary hypertension (PH). PH can also occur in the absence of significant lung damage, leading clinicians to question whether pulmonary TB may cause pulmonary arterial hypertension (PAH), an entity that has not been otherwise described. Read More

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December 2020

Transient Cardiac Dysfunction Following a Cerebrovascular Accident.

Cureus 2021 Jun 29;13(6):e16023. Epub 2021 Jun 29.

Internal Medicine, Jersey Shore University Medical Center/Saint Francis Medical Center Program, Trenton, USA.

Acute cerebral injuries are often accompanied by sudden electrocardiogram (ECG) changes such as cardiac arrhythmias, QT prolongation, and abnormal T-wave morphology. One rare phenomenon is "cerebral T-waves", which are T-waves observed in the context of stroke and described as transient, symmetric, and deeply inverted. The classic cerebral T wave is defined as a T-wave inversion of ≥5 mm depth in at least four contiguous precordial leads, and it is more commonly observed in the setting of acute ischemic stroke rather than hemorrhagic stroke. Read More

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Case Report: Prenatal Diagnosis and Treatment of Fetal Autoimmune-Associated First-Degree Atrioventricular Block: First Report From China.

Front Cardiovasc Med 2021 21;8:683486. Epub 2021 Jun 21.

Department of Paediatric Cardiology, West China Second University Hospital, Sichuan University, Chengdu, China.

The rapid progression from fetal first-degree atrioventricular block (AVB) to third-degree AVB had been reported. However, how to define fetal first-degree AVB with proper technique and the necessity of the treatment for fetal autoimmune-associated first-degree AVB are still controversial. To explore the diagnosis and the effect of treatment for fetal first-degree AVB. Read More

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A Rare Case of Third Ventricular Glioblastoma.

Medeni Med J 2021 18;36(2):167-171. Epub 2021 Jun 18.

Cantonal Hospital Zenica, Department of Radiology, Bosnia and Herzegovina.

Glioblastoma, also known as glioblastoma multiforme, is an aggressive type of cancer that is made up of abnormal astrocytic cells, but also contain a mixture of different cell types (including blood vessels) and areas of necrosis. It is often seen in the brain and spinal cord, but glioblastomas are rarely found in the third ventricle. In this case, it was diagnosed in a 22-year-old male patient and we intended to draw attention to its atypical localization and surgical access to this third ventricle glioblastoma. Read More

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The Monocyte to High-Density Lipoprotein Cholesterol Ratio Is Associated with Left Ventricular Diastolic Function in Patients with No Significant Perfusion Abnormality.

Int Heart J 2021 Jul 6. Epub 2021 Jul 6.

Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences.

The monocyte to high-density lipoprotein cholesterol (HDL-C) ratio has been considered to be a prognostic marker. Whether this ratio is associated with left ventricular (LV) diastolic function remains undetermined. We tested the hypothesis that the monocyte to HDL-C ratio is associated with LV diastolic parameters derived from gated myocardial perfusion single-photon emission computed tomography (SPECT) in patients with no significant perfusion abnormality. Read More

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Analysis of left ventricular function, left ventricular outflow tract and aortic valve area using computed tomography: Influence of reconstruction parameters on measurement accuracy.

Br J Radiol 2021 Aug 8;94(1124):20201306. Epub 2021 Jul 8.

Department of Cardiology, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany.

Objectives: Computed tomography (CT) allows reproducible assessment of left ventricular (LV) function, left ventricular outflow tract area (LVOT) and aortic valve area (AVA). We evaluated the influence of image reconstruction parameters on these measurements.

Methods: We analyzed 45 contrast-enhanced, retrospectively ECG-gated CT datasets acquired on a third-generation dual source system. Read More

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Elevated Plasma Homocysteine Level Associated with Further Left Ventricular Structure and Function Damages in Type 2 Diabetic Patients: A Three-Dimensional Speckle Tracking Echocardiography Study.

Metab Syndr Relat Disord 2021 Jul 5. Epub 2021 Jul 5.

Department of Ultrasound, Xinqiao Hospital, The Third Military Medical University, Chongqing, China.

The aims of this study were to explore the left ventricular (LV) structural remodeling and its risk factors in type 2 diabetes mellitus (T2DM) patients with or without hyperhomocysteinemia (hHcy) and to detect the accompanied LV dysfunction using three-dimensional speckle tracking echocardiography (3DSTE). There were totally 80 T2DM patients with undamaged LV ejection fraction (≥55%) in this study, 40 of whom were also diagnosed with hHcy as co-morbidity. Forty age- and gender-matched controls were also recruited. Read More

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Arcuate nucleus, median eminence, and hypophysial pars tuberalis.

Handb Clin Neurol 2021 ;180:227-251

Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

The arcuate nucleus (ARC) is located in the mediobasal hypothalamus and forms a morphological and functional entity with the median eminence (ME), the ARC-ME. The ARC comprises several distinct types of neurons controlling prolactin release, food intake, and metabolism as well as reproduction and onset of puberty. The ME lacks a blood-brain barrier and provides an entry for peripheral signals (nutrients, leptin, ghrelin). Read More

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January 2021

Circulating Soluble Suppression of Tumorigenicity 2 Predicts Recurrence After Radiofrequency Ablation of Persistent Atrial Fibrillation.

Front Cardiovasc Med 2021 17;8:653312. Epub 2021 Jun 17.

Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

A more extensively fibrotic left atrium contributes to atrial fibrillation (AF) occurrence, persistence, and recurrence. The soluble suppression of tumorigenicity 2 (sST2) has emerged as a ventricular fibrotic biomarker for patients with heart failure. The present study is to investigate associations between circulating sST2 and risk of recurrence after ablation in AF patients. Read More

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Endoscopic resection of a low-grade ependymoma of the pineal region.

Surg Neurol Int 2021 14;12:279. Epub 2021 Jun 14.

Department of Neurosurgery, Geneva University Hospitals, Geneva, Switzerland.

Background: Full endoscopic resection of solid brain tumors represents a challenge for neurosurgeons. This can be achieved with modern technology and advanced surgical tools.

Case Description: A 23-years-old male was referred to our unit with raised intracranial pressure. Read More

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Effectiveness of medical therapy for treatment of idiopathic frequent premature ventricular complexes.

J Cardiovasc Electrophysiol 2021 Jul 2. Epub 2021 Jul 2.

Heart Rhythm Services, Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada.

Introduction: The relative effectiveness of medical therapy compared with a conservative approach of monitoring in patients with idiopathic frequent premature ventricular complexes (PVCs) is uncertain. We evaluated the effectiveness of medical versus conservative therapy for frequent PVCs.

Methods: Patients with frequent PVCs (≥5%) were prospectively enrolled in this cohort study between 2016 and 2020. Read More

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Endoscopic Third Ventriculostomy in the Fourth Ventricle Outlet Obstruction Associated with Chiari Malformation Type I and Syringomyelia: Case Report.

Asian J Neurosurg 2021 Jan-Mar;16(1):170-173. Epub 2021 Feb 23.

Department of Neurosurgery, National Hospital Center, Nouakchott, Mauritania.

Hydrocephalus by the fourth ventricle outlet obstruction (FVOO) associated with a Chiari malformation type I and syringomyelia is a well-known entity but a rare situation in clinical practice. Although suboccipital craniectomy with the opening of the obstruction membrane appears to be the most physiological approach, by restoring the original pathway of cerebrospinal fluid flow, the endoscopic third ventriculostomy (ETV) represents an important minimally invasive alternative. We report the case of an adult patient with tetra ventricular hydrocephalus by FVOO associated with Chiari malformation and syringomyelia. Read More

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February 2021

Cardiac Magnetic Resonance to Detect the Underlying Substrate in Patients with Frequent Idiopathic Ventricular Arrhythmias.

Diagnostics (Basel) 2021 Jun 18;11(6). Epub 2021 Jun 18.

First Department of Cardiology, AHEPA Hospital, Faculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, 546 36 Thessaloniki, Greece.

Background: A routine diagnostic work-up does not identify structural abnormalities in a substantial proportion of patients with idiopathic ventricular arrhythmias (VAs). We investigated the added value of cardiac magnetic resonance (CMR) imaging in this group of patients.

Methods: A single-centre prospective study was undertaken of 72 patients (mean age 46 ± 16 years; 53% females) with frequent premature ventricular contractions (PVCs ≥ 500/24 h) and/or non-sustained ventricular tachycardia (NSVT), an otherwise normal electrocardiogram, normal echocardiography and no coronary artery disease. Read More

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The effect of long-term left ventricular assist device support on flow-sensitive plasma microRNA levels.

Int J Cardiol 2021 Jun 29. Epub 2021 Jun 29.

Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

Background: Implantation of current generation left ventricular assist devices (LVADs) in the treatment of end-stage heart failure (HF), not only improves HF symptoms and end-organ perfusion, but also leads to cellular and molecular responses, presumably in response to the continuous flow generated by these devices. MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression in multiple biological processes, including the pathogenesis of HF. In our study, we examined the influence of long-term LVAD support on changes in flow-sensitive miRNAs in plasma. Read More

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Post-discharge arrhythmic risk stratification of patients with acute myocarditis and life-threatening ventricular tachyarrhythmias.

Eur J Heart Fail 2021 Jul 1. Epub 2021 Jul 1.

Cardiothoracovascular Department, Azienda Sanitaria Universitaria Integrata di Trieste and University of Trieste, Trieste, Italy.

Aims: The outcomes of patients presenting with acute myocarditis and life-threatening ventricular arrhythmias (LT-VA) are unclear. The aim of this study was to assess the incidence and predictors of recurrent major arrhythmic events (MAEs) after hospital discharge in this patient population.

Methods And Results: We retrospectively analysed 156 patients (median age 44 years; 77% male) discharged with a diagnosis of acute myocarditis and LT-VA from 16 hospitals worldwide. Read More

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