7,550 results match your criteria third parturition

Effect of maternal overnutrition on predisposition to insulin resistance in the foal: Foal skeletal muscle development and insulin signaling.

Domest Anim Endocrinol 2021 Jul 2;77:106648. Epub 2021 Jul 2.

Department of Animal Science, Texas A&M University, College Station, Texas 77843. Electronic address:

Skeletal muscle plays an integral role in the ability of a horse to perform at high levels. Shifts in skeletal muscle development in response to maternal plane of nutrition may have substantial and lasting impacts on athletic performance and whole-body metabolism. Therefore, sixteen Quarter Horse mares were used in a completely randomized design and maintained at a body condition score (BCS) 6 until start of third trimester. Read More

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Case Report of Ogilvie's Syndrome Following Emergency Haemostatic Subtotal Abdominal Hysterectomy at University Teaching Hospital of Butare, Rwanda.

East Afr Health Res J 2020 26;4(1):17-19. Epub 2020 Jun 26.

College of Medicine and Health Sciences, University of Rwanda.

Background: Acute colonic pseudo-obstruction or Ogilvie's syndrome is a rare condition that usually develops due to a dysregulated autonomic nervous system following a medical or surgical condition. With delayed diagnosis, it may lead to bowel ischemia and perforation with poor prognosis.

Case: We report a case of a 33 years old female, Gravida 1, Para1, who developed severe abdominal distension following abdominal haemostatic hysterectomy due to a severe postpartum haemorrhage and shock requiring epinephrine infusion after a spontaneous vaginal delivery. Read More

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[Avoidability of fetal deaths: reflections on the Brazilian List of Avoidable Causes of Deaths through interventions by the Brazilian Unified National Health System].

Cad Saude Publica 2021 19;37(7):e00265920. Epub 2021 Jul 19.

Departamento de Patologia, Universidade Federal Fluminense, Niterói, Brasil.

Although the Brazilian List of Avoidable Causes of Deaths (LBE in Portuguese), in its version for children under 5 years of age (LBE < 5), does not include stillbirths, some studies have used the list with or without adaptations. We present a proposal for adaptation of the LBE for stillbirths (LBE-OF in Portuguese) and the results of its application to stillbirths in the State of Rio de Janeiro, Brazil, in 2018, compared to the results with LBE < 5. We reviewed the categories from the 10th revision of the International Classification of Diseases (ICD-10) in the LBE < 5 and reassigned them in the avoidability groups, according to time of death in relation to delivery and the causes consistent with stillbirths. Read More

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Shock caused by spontaneous rupture uterine vessels during puerperal period: a case report and literature review.

Eur Rev Med Pharmacol Sci 2021 Jul;25(13):4451-4455

Tianjin Third Central Hospital, Obstetrics & Gynecology Department, Hedong District, China; Technology Research Central of Public Health Ministry, Tianjin, China.

Hemoperitoneum caused by spontaneous rupture of uterine vessels during delivery is relatively rare in obstetric hemorrhage, and even rarer during the puerperal period. It can be life-threatening without timely diagnosis and treatment; therefore, the literature on this topic is very scarce. To explore its etiology and identify its diagnosis and treatment principle, we are reporting a case of shock caused by spontaneous rupture of uterine vessels admitted in our hospital. Read More

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Prenatal Stress and Psychiatric Symptoms During Early Phases of the COVID-19 Pandemic in Italy.

Int J Womens Health 2021 6;13:653-662. Epub 2021 Jul 6.

Unit of Psychiatry, Department of Medicine (DAME), University of Udine, Udine, Italy.

Purpose: In February 2020, Italy became the first European country to face the coronavirus disease 2019 (COVID-19) outbreak. The concerns of infection, financial worries, loss of freedom, and isolation during the ongoing pandemic can lead to negative psychological effects, including anxiety, depression, and obsessive-compulsive disorder. The main aim of our study was to evaluate the relationship between pandemic-related stress and pregnancy-specific stress and assess their role in the development of psychiatric symptoms. Read More

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Case Report: Clinical and Pharmacokinetic Profile of Lithium Monotherapy in Exclusive Breastfeeding. A Follow-Up Case Series.

Front Pharmacol 2021 24;12:647414. Epub 2021 Jun 24.

Perinatal Mental Health Clinic-BCN Unit, Department of Psychiatry and Psychology, Hospital Clínic, Department of Medicine, Institute of Neuroscience, University of Barcelona (UB), Institut D'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), and Centro de Investigación Biomédica en Red en Salud Mental (CIBERSAM), Barcelona, Spain.

Most guidelines advise that women taking lithium should not breastfeed. The variation in transfer is just one reason behind this advice. To present clinical and pharmacokinetic data of nine mother-infant pairs exposed to lithium monotherapy during late pregnancy and exclusive breastfeeding at the Perinatal Psychiatric Unit (2006-2018). Read More

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Managing Reproduction Emergencies in the Field: Part 2: Parturient and Periparturient Conditions.

Vet Clin North Am Equine Pract 2021 Aug;37(2):367-405

Department of Animal Sciences, Cal Poly University San Luis Obispo, 1 Grand Avenue, San Luis Obispo, CA 93407, USA. Electronic address:

Selected conditions affecting broodmares are discussed, including arterial rupture, dystocia, foal support with ex utero intrapartum treatment, uterine prolapse, postpartum colic, the metritis/sepsis/systemic inflammatory response syndrome complex, and retained fetal membranes. Postpartum colic beyond third-stage labor contractions should prompt comprehensive evaluation for direct injuries to the reproductive tract or indirect injury of the intestinal tract. Mares with perforation or rupture of the uterus are typically recognized 1 to 3 days after foaling, with depression, fever, and leukopenia; laminitis and progression to founder can be fulminant. Read More

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Recommendations for improving primiparous women's childbirth experience: results from a multiphase study in Iran.

Reprod Health 2021 Jul 6;18(1):146. Epub 2021 Jul 6.

Social Determinants of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Background: Women's satisfaction with childbirth experience is considered as one of the quality indicators of the maternity services across the world. However, there is no guideline for improving the experience of childbirth in Iran that is suitable for women with different cultural, economic, and social statuses. The aim of this study is to make recommendations for practice and propose a clinical guideline for improving the experience of women with vaginal births. Read More

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Editorial: Maternal SARS-CoV-2 Infection and Pregnancy Outcomes from Current Global Study Data.

Dinah V Parums

Med Sci Monit 2021 Jul 5;27:e933831. Epub 2021 Jul 5.

Science Editor, Medical Science Monitor, International Scientific Information, Inc., Mellville, NY, USA.

During the global COVID-19 pandemic, data from clinical studies, systematic review, and population registry data have shown that when compared with non-pregnant women, SARS-CoV-2 infection in pregnancy is associated with a small increase in risk to the mother. Large cohort studies and registry data collected from 2020 have included the US Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET), COVI-PREG, the UK and Global Pregnancy and Neonatal Outcomes in COVID-19 (PAN-COVID) study, the American Academy of Pediatrics (AAP) Section on Neonatal-Perinatal Medicine (SONPM) National Perinatal COVID-19 Registry, the Swedish Pregnancy Register, and the Canadian Surveillance of COVID-19 in Pregnancy (CANCOVID-Preg) registry. Recently published data have shown that most maternal infections with SARS-CoV-2 occur during the third trimester and result in a small increase in hospital admission, admission to the intensive care unit (ICU), mechanical ventilation, preterm birth, and increased cesarean sections in mothers infected with SARS-CoV-2. Read More

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Short-term outcome of pregnant women vaccinated by BNT162b2 mRNA COVID-19 vaccine.

Ultrasound Obstet Gynecol 2021 Jul 1. Epub 2021 Jul 1.

Department of Obstetrics and Gynecology, Sheba Medical Center, Tel -Hashomer, Israel.

Objective: To determine the immunogenicity and reactogenicity of Pfizer's BNT162b2 COVID-19 vaccine among pregnant women compared with non-pregnant women, and to evaluate the obstetric outcome following vaccination.

Methods: An observational case-control study of pregnant women, who were vaccinated by a 2-dose regimen of BNT162b2 vaccine during gestation between January-February 2021 (study group) and were compared to age-matched non-pregnant women who received the vaccine during the same time period (control group). Participants received a digital questionnaire 1-4 weeks after the second dose and were asked to provide information regarding demographics, medications, medical history, history of prior SARS-CoV-2 infection, timing of COVID-19 vaccine doses, and side effects after each vaccine dose. Read More

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Human Coronavirus Infections and Pregnancy.

Matern Fetal Med 2021 Jan 21;3(1):53-65. Epub 2020 Sep 21.

Department of Obstetrics and Gynecology, Third People's Hospital of Shenzhen, Shenzhen, Guangdong 518020, China.

Human coronavirus (HCoV) causes potentially fatal respiratory disease. Pregnancy is a physiological state that predisposes women to viral infection. In this review, we aim to present advances in the pathogenesis, clinical features, diagnosis, and treatment in HCoV in pregnancy. Read More

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January 2021

Differences in obstetric healthcare utilization and delivery complications before and after the COVID-19 pandemic - a retrospective study.

J Matern Fetal Neonatal Med 2021 Jun 28:1-6. Epub 2021 Jun 28.

Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel.

Purpose: To investigate the effect of the COVID-19 pandemic on healthcare utilization related to labor and delivery and to assess the effect of the COVID-19 pandemic on intra-partum and delivery complications.

Methods: This retrospective study was performed at a university-affiliated, tertiary medical center. It included women admitted to the delivery room from 1 March 2020 to 23 July 2020 during the first wave of the COVID-19 pandemic. Read More

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Development and validation of a predictive model for severe postpartum hemorrhage in women undergoing vaginal delivery: A retrospective cohort study.

Int J Gynaecol Obstet 2021 Jun 24. Epub 2021 Jun 24.

Department of Obstetrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou City, Guangdong Province, China.

Objective: To develop a predictive tool to accurately screen women at high risk of severe postpartum hemorrhage (SPPH) undergoing vaginal delivery.

Methods: We analyzed 28 150 mothers who underwent vaginal delivery after 28 weeks of pregnancy in the Third Affiliated Hospital of Guangzhou Medical University from January 2015 to August 2019. Two-thirds of the cohort were randomly allocated to a training set (n = 18 766) and the rest to a validation set (n = 9384). Read More

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Appendicitis with concurrent COVID-19 infection in a patient during the third trimester of pregnancy.

BMJ Case Rep 2021 Jun 23;14(6). Epub 2021 Jun 23.

Obstetrics and Gynaecology, Shrewsbury and Telford Hospital NHS Trust Maternity Services, Telford, UK.

This article presents an unusual case of appendicitis in pregnancy complicated by the novel coronavirus (SARS-CoV-2). The novel coronavirus has affected the way medicine is practised across most parts of the world with over 160 000 000 global cases to date. Tackling management of these cases is more complex when other pathological processes are ongoing. Read More

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Bundle to care for newborn children of mothers with suspected or confirmed diagnosis of COVID-19.

Rev Gaucha Enferm 2021 18;42(spe):e20200391. Epub 2021 Jun 18.

Universidade Federal do Triângulo Mineiro (UFTM). Uberaba, Minas Gerais, Brasil.

Objective: To build and validate the contents of a bundle for the care of newborn children of mothers with suspected or confirmed diagnosis of COVID-19 in the delivery room and in the rooming-in care.

Method: Methodological research, developed in 2020 in three stages: bibliographic survey, construction of the instrument in Google Forms® and content validation by seven judges. The initial instrument consisted of seven nursing care. Read More

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Wiad Lek 2021 ;74(4):934-939


Objective: The aim: To obtain the first national estimates of the current prevalence rate of SSI after CSEC and antimicrobial resistance of causing pathogens in Ukraine.

Patients And Methods: Materials and methods: We performed a retrospective multhicentre cogort study based surveillance data was conducted from May 2017 to December 2019. The study population consisted of all women who had a cesarean section in 11 regional women hospitals of Ukraine. Read More

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Fetal heart rate mirrors maternal temperature during posterior fossa craniotomy: a case report.

Int J Obstet Anesth 2021 Aug 25;47:103193. Epub 2021 May 25.

Department of Anesthesiology, Perioperative, and Pain Medicine, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA. Electronic address:

While it is well known that maternal temperature affects fetal heart rate, the exact relationship is not well described. The circumstances accompanying most cases of maternal hypothermia and rewarming (e.g. Read More

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Pelvic floor dysfunction one year after first childbirth in relation to perineal tear severity.

Sci Rep 2021 Jun 15;11(1):12560. Epub 2021 Jun 15.

Department of Clinical Sciences, Obstetrics and Gynecology, Umeå University, 901 87, Umeå, Sweden.

The aims of this study were to evaluate pelvic floor dysfunction symptoms one year after delivery and investigate whether adverse functional outcomes after childbirth were related to the degree of perineal injury. A prospective cohort of 776 primiparas were included. Self-reported pelvic floor function data were obtained using a web-based questionnaire. Read More

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Obstetric Lacerations: Prevention and Repair.

Am Fam Physician 2021 06;103(12):745-752

Travis Air Force Base Family Medicine Residency, Travis Air Force Base, CA, USA.

Obstetric lacerations are a common complication of vaginal delivery. Lacerations can lead to chronic pain and urinary and fecal incontinence. Perineal lacerations are defined by the depth of musculature involved, with fourth-degree lacerations disrupting the anal sphincter and the underlying rectal mucosa and first-degree lacerations having no perineal muscle involvement. Read More

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Randomized Trial of Fetal Surgery for Severe Left Diaphragmatic Hernia.

N Engl J Med 2021 07 8;385(2):107-118. Epub 2021 Jun 8.

From the Department of Obstetrics and Gynecology, KU Leuven (J.A.D., F.M.R.) and Academic Department of Development and Regeneration, Biomedical Sciences, University Hospitals KU Leuven, Leuven, Belgium (J.A.D., B.V.C., F.M.R.); King's College Hospital (K.H.N.) and the Institute for Women's Health, University College London Hospital (J.A.D.) - both in London; Hospital Antoine-Béclère, Université Paris-Saclay, Clamart, France (A.B.); Hospital Clinic and Sant Joan de Déu, Barcelona (E.G.); Mount Sinai Hospital, Toronto (G.R.); Hospital Maggiore Policlinico, Milan (N.P.); the National Center for Child Health and Development, Tokyo (H.S.); Children's Memorial Hermann Hospital, Houston (A.J.); the Medical University of Warsaw, Warsaw, Poland (M.W.); and University Hospital Bonn, Bonn, Germany (C.B.).

Background: Observational studies have shown that fetoscopic endoluminal tracheal occlusion (FETO) has been associated with increased survival among infants with severe pulmonary hypoplasia due to isolated congenital diaphragmatic hernia on the left side, but data from randomized trials are lacking.

Methods: In this open-label trial conducted at centers with experience in FETO and other types of prenatal surgery, we randomly assigned, in a 1:1 ratio, women carrying singleton fetuses with severe isolated congenital diaphragmatic hernia on the left side to FETO at 27 to 29 weeks of gestation or expectant care. Both treatments were followed by standardized postnatal care. Read More

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Obstetric anal sphincter injury following previous vaginal delivery.

Int Urogynecol J 2021 Jun 8. Epub 2021 Jun 8.

Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, PO Box 12000, Jerusalem, Ein Kerem, Israel.

Introduction And Hypothesis: Obstetric anal sphincter injury (OASI) is a debilitating complication of vaginal delivery. The aim of this study was to identify risk factors for OASI in women with a previous vaginal delivery. We further attempted to detect specific risk factors for severe OASI in this subgroup. Read More

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Maternal bile acid profile and subtype analysis of intrahepatic cholestasis of pregnancy.

Orphanet J Rare Dis 2021 06 7;16(1):259. Epub 2021 Jun 7.

The Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Background: ICP pregnant women have a unique profile of serum bile acid metabolism, thus the early and accurate identification of ICP patients is beneficial to early appropriate treatment and improvement of pregnancy outcomes. In this study, ultra-high performance liquid chromatography-mass spectrometry/mass spectrometry (UPLC-MS/MS) was used to analyze the 15 types of serum bile acid profiles among patients with ICP in third trimester, patients with cholelithiasis, and patients with hepatitis B virus. The ICP diagnostic model established by partial least squares-discriminant analysis (PLS-DA) was used to screen the differential bile acids for clinical subtypes of ICP. Read More

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19-hydroxy Steroids in the Aromatase Reaction: Review on Expression and Potential Functions.

J Endocr Soc 2021 Jul 23;5(7):bvab050. Epub 2021 Mar 23.

Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.

Scientific evidence related to the aromatase reaction in various biological processes spanning from mid-1960 to today is abundant; however, as our analytical sensitivity increases, a new look at the old chemical reaction is necessary. Here, we review an irreversible aromatase reaction from the substrate androstenedione. It proceeds in 3 consecutive steps. Read More

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A clinical audit of management of third and fourth degree perineal tears.

J Pak Med Assoc 2021 May;71(5):1446-1449

Department of Obstetrics and Gynecology, Aga Khan University, Karachi, Pakistan.

Objective: To perform a clinical audit of the practices related to the management of third and fourth degree perineal tears.

Methods: The retrorspective study was conducted in 2019 at the Aga Khan University Hospital, Karachi, and comprised medical records from January 2008 to December 2018 of women having singleton term vaginal delivery and sustaining obstetric anal sphincter injuries. The change in practices regarding tear management was compared with a previous audit done at the same institution in 2008. Read More

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Analysis of in vitro fertilization/intracytoplasmic sperm injection outcomes in infertile women with a history of thyroid cancer: a retrospective study.

Reprod Biol Endocrinol 2021 Jun 4;19(1):82. Epub 2021 Jun 4.

Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, 49 North Garden Rd, Beijing, 100191, China.

Background: Recent studies have revealed that women with infertility have a higher risk of thyroid cancer (TC) than fertile women. However, studies on whether a history of thyroid cancer affects clinical outcomes in women who conceive using in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) are scarce. We investigate whether a history of thyroid cancer (TC) affects the in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) outcomes and increases the risk of adverse obstetric outcomes in women with infertility. Read More

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A gastrointestinal nematode in pregnant and lactating mice alters maternal and neonatal microbiomes.

Int J Parasitol 2021 May 31. Epub 2021 May 31.

Institute of Parasitology, McGill University (Macdonald Campus), 21 111 Lakeshore Road, Ste-Anne-de-Bellevue, Québec H9X 3V9, Canada. Electronic address:

The maternal microbiome is understood to be the principal source of the neonatal microbiome but the consequences of intestinal nematodes on pregnant and lactating mothers and implications for the neonatal microbiome are unknown. Using pregnant CD1 mice infected with Heligmosomoides bakeri, we investigated the microbiomes in maternal tissues (intestine, vagina, and milk) and in the neonatal stomach using MiSeq sequencing of bacterial 16S rRNA genes. Our first hypothesis was that maternal nematode infection altered the maternal intestinal, vaginal, and milk microbiomes and associated metabolic pathways. Read More

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Obstetric and Perinatal Outcomes after Very Early Preterm Premature Rupture of Membranes (PPROM)-A Retrospective Analysis over the Period 2000-2020.

Medicina (Kaunas) 2021 May 11;57(5). Epub 2021 May 11.

Department of Obstetrics and Gynecology, University Hospital of Jerez de la Frontera, Faculty of Medicine, University of Cadiz, 11407 Cadiz, Spain.

: Pre-term premature rupture of membranes (PPROM) responds for one third of preterm births, and it is associated with other complications that increase the risk of maternal or fetal poor outcome. To reduce uncertainty and provide accurate information to patients, the analysis of the large series is of great importance. In order to learn about the evolution over the time of the obstetric and perinatal outcomes in cases of PPROM at, or before, 28 weeks (very early PPROM) managed with an expectant/conservative protocol, we have designed the present study. Read More

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Effectiveness of psychological interventions in the treatment of perinatal depression: A systematic review of systematic reviews and meta-analyses.

J Affect Disord 2021 08 13;291:294-306. Epub 2021 May 13.

Department of Psychiatry, Eginition Hospital, University of Athens, Greece.

Background: Perinatal depression is a high prevalent mental health problem with serious consequences. Evidence about effective psychological interventions in treating perinatal depression has been increasing, but it lacks a comprehensive synthesis of findings.

Methods: A systematic review of systematic reviews and meta-analyses concerning the effectiveness of psychological interventions in treating perinatal depression (depression during pregnancy and the first 12 months postpartum) in adult women was conducted. Read More

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Intrapartum interventions and outcomes for women and children following induction of labour at term in uncomplicated pregnancies: a 16-year population-based linked data study.

BMJ Open 2021 05 31;11(6):e047040. Epub 2021 May 31.

School of Nursing and Midwifery, Western Sydney University, Penrith South, New South Wales, Australia.

Objectives: We compared intrapartum interventions and outcomes for mothers, neonates and children up to 16 years, for induction of labour (IOL) versus spontaneous labour onset in uncomplicated term pregnancies with live births.

Design: We used population linked data from New South Wales, Australia (2001-2016) for healthy women giving birth at 37+0 to 41+6 weeks. Descriptive statistics and logistic regression were performed for intrapartum interventions, postnatal maternal and neonatal outcomes, and long-term child outcomes adjusted for maternal age, country of birth, socioeconomic status, parity and gestational age. Read More

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A randomized pilot clinical trial of pravastatin versus placebo in pregnant patients at high risk of preeclampsia.

Am J Obstet Gynecol 2021 May 24. Epub 2021 May 24.

Department of Obstetrics and Gynecology, University of Texas Medical Branch at Galveston, Galveston, TX.

Background: Preeclampsia remains a major cause of maternal and neonatal morbidity and mortality. Biologic plausibility, compelling preliminary data, and a pilot clinical trial support the safety and utility of pravastatin for the prevention of preeclampsia.

Objective: We previously reported the results of a phase I clinical trial using a low dose (10 mg) of pravastatin in high-risk pregnant women. Read More

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